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Journal of Bionic Engineering 2020年第6期17卷 1209-1223页

作者： maryam mohammadi Sayed Mahmood Rabiee Saeed Hesaraki Department of Materials Engineering Babol Noshirvani University of TechmologyBabol 71167-47148Iran Nanotechnologv and Advanced Materials Materials and Energy Research CenterKaraj ***AlborzIran

The effect of concurrent attendance of two inhibitors of bone degradation,namely Alendronate(Aid)sodium trihydrate and Strontium(Sr),on Calcium Phosphate Cement(CPC)characteristics was *** this aim,5 wt%Strontium and 21 mM Alendronate sodium trihydrate were used in calcium phosphate cement and setting time,ion and drug release were ***264.7 and G cell were cultured on cement samples and Tartrate-Resistant Acid Phosphatase(TRAP),Alkaline phosphatase(ALP)activity and MTT assay were *** results of structural analysis indicated that 21 mM Aid did not let the cement ***,colloidal silica was added to the cement formula and successfully decreased the setting *** vitro tests showed Sr-loaded sample had a greater inhibitory effect on biocompatibility of G cells than Aid-loaded and Sr-Ald-loaded *** addition,the findings about osteoblast MTT and ALP activity indicated that Sr was more effective in osteogenic activity of G *** simultaneous presence of Aid and Sr in Calcium Phosphate Cement(CPC)was not as effective in its biocompatibility as the presence of Sr alone.

关键词： calcium phosphate cements drug release alendronate sodium trihydrate strontium RAW264.7 cell G cell

Mobilizing the seed storage oil in milk thistle (Silybum marianum) can supply energy for seed germination and early seedling growth and apply as TAGs breakdown marker

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Oil Crop Science 2023年第4期8卷 207-216页

作者： Mohammad Shahin Daneshmandi maryam mohammadi maryam Asadi Adele Robati Department of Plant Production Faculty of Agriculture Science and Natural ResourcesUniversity of Torbat HeydariehP.O.Box 95161-68595Torbat HeydariehIran

Milk thistle(Silybum marianum)is a crucial medicinal plant containing a large amount of *** the study,the changes in storage oil during seed germination and seedling transition from heterotrophic phases were *** results showed that seed oil decreased from 19.53%to 0.88%on the 7th day of seedling *** hydrolysis continued until the 4th day of germination with a low slope,but then increased the use of oils in seed germination end seedling growth *** results indicated that the quantitative changes in fatty acids,presented at lower amount,were relatively higher than dominant fatty *** were decreasing phenolic content in the developing seedlings,but overall,lowest level of total phenolic content can be attributed to the control(30.52 mg⋅100 g⋅Oil^(-1)).In contrast,the maximum peroxide value(2.58 meq⋅kg Oil^(-1))in the developing seedling was observed on the last day of the *** results showed that there was a significant correlation between saturated fatty acid,unsaturated fatty acid,and lipase ***,the correlation between lipase activity and polyunsaturated fatty acids was significantly higher than between lipase activity and monounsaturated fatty acids(R^(2)=90%and R^(2)=77%,respectively).Therefore,the lipolysis process acts selectively in milk thistle *** to the results,C12:0 exhibits a greater impact on the early seedling growth rather than on the germination process and is one of the determining factors in the transition from heterotroph to ***,it can be a marker for TAGs breakdown.

关键词： Fatty acid Lipase Milk thistle Lauric acid TAGs Total polyphenol

Phytochemical composition of the essential oil of different populations of Stachys lavandulifolia Vahl

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Asian Pacific Journal of Tropical Biomedicine 2013年第2期3卷 123-128页

作者： Abdollah Ghasemi Pirbalouti maryam mohammadi Shahrekord Branch Islamic Azad UniversityDepartment of Medicinal Plants Stockbridge School of Agriculture College of Natural SciencesUniversity of Massachusetts

Objective:To examine the chemical variability in inflorescences of wild populations of Stachys lavandulifolia Vahl(***)collected throughout two provinces(lsfahan and Chaharmahal va Bakhtiary),Southwest ***:The essential oils of *** Vahl from seven locations were obtained by hydro-distillation and analysed by gas chromatography and gas chromatography-mass ***:The results revealed that distinct differences in the content of compounds depending on region of sample *** main constituents of the essential oils wereα-thujone(0.3%-32.3%),α-pinene(trace to 37.3%),myrcene(0.5%-15.9%),β-phellandrene(1.1%-37.9%),germacrene D(0.4%-11.3%),△-cadinene(trace to 11.6%)and 1,4-methano-1 H-indene(trace to 10.1%).Conclusions:The results of the present study indicated that essential oil components of *** Vahl can be varied with genetic(ecotype),environmental conditions and geographic origin,In general,the essential oils of various populations of *** Vahl were rich in monoterpenoids and sesquiterpenoids.

关键词： Stachys lavandulifolia Vahl Lamiaceae Essential oil α-thujene α-pinene β-phellandrene Chemotype

A Randomized,Double Blinded,Placebo-Controlled Clinical Trial of Silymarin in Ulcerative Colitis

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Chinese Journal of Integrative Medicine 2015年第12期21卷 902-906页

作者： Mansoor Rastegarpanah Reza Malekzadeh Homayoun Vahedi maryam mohammadi Elham Elahi Meghedi Chaharmahali Tahereh Safarnavadeh Mohammad Abdollahi Digestive Disease Research Center Tehran University of Medical Sciences Faculty of Pharmacy Tehran University of Medical Sciences Pharmaceutical Sciences Research Center Tehran University of Medical Sciences Islamic Azad University Pharmaceutical Branch

Objective： To evaluate the clinical efficacy of silymarin in ulcerative colitis （UC） patients. Methods： A randomized double blinded placebo-controlled clinical trial was conducted in 80 UC patients whose disease had been documented and were in remission state between September 2009 and October 2010. Patients were assigned to silymarin group （42 cases） and placebo group （38 cases） using a random number table. Either silymarin （140 mg） or placebo （lactose mono-hydrate, corn starch magnesium stearate） tablets were given once daily for 6 months along with their standard therapy. The efficacies were assessed by disease activity index （DAI）, frequency difference of the disease flare-up, and paraclinical data. Results： Ten patients （4 in the silymarin group due to nausea and 6 in the placebo group due to disease flare-up and abdominal pain） discontinued the study. An improvement in hemoglobin level （11.8± 1.6 g/dL vs. 13.4± 1.2 g/dL, P〈0.05） and erythrocyte sedimentation rate （23.7 ＋_ 11.5 mm/h vs.10.8＋ 3.2 mm/h, P〈0.05） was observed in the silymarin group but not in the placebo group. DAI significantly decreased in the silymarin group and reached from 11.3 ± 3.5 to 10.7±2.8 （P〈0.05）. Thirty-five out of 38 patients in the silymarin group were in complete remission with no flare-up after 6 months as compared to 21 out of 32 patients in the placebo group （P=0.5000）. Conclusion： Silymarin as a natural supplement may be used in UC patients to maintain remission.

关键词： silymarin ulcerative colitis randomized controlled trial

Identification of Panton-Valentine leukocidin virulence gene in methicillin-resistant Staphylococcus aureus isolated from clinical specimens of burn patients in Zare Hospitals of Sari, Iran

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Journal of Acute Disease 2020年第3期9卷 121-125页

作者： Atefeh Ranjkesh Zahra Salari Mehrab Nejati Emad Behboudi Ali Ramezani Milad Zandi Mahmood Marzban Hadis Kiani Mina Bavi Mehdi Rabiei Roodsari Yousef Esvand Zibaee Samaneh Abbasi maryam mohammadi Elyasi Mehdi Parsanahad Shahram Jalilian Siminmohammadi Gorji Mina Owrang Faculty of Medicine Sari BranchIslamic Azad UniversitySariIran School of Medicine Bam University of Medical SciencesBamIran Department of Microbiology Faculty of MedicineGolestan University of Medical SciencesGorganIran Virology Department School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Nursing School of Tabas Birjand University of Medical SciencesBirjandIran Department of Virology School of Public HealthTehran University of Medical SciencesTehranIran Department of Laboratory Sciences Borujerd Branch Islamic Azad UniversityBorujerdIran Abadan Faculty of Medical Sciences AbadanIran School of Paramedical Sciences Dezful University of Medical SciencesDezfulIran

Objective:To identify the pathogenic gene of Panton-Valentine leukocidin in methicillin-resistant Staphylococcus aureus strain isolated from clinical specimens of burn patients in Shaheed Zare Burn ***:A total of 104 samples of Staphylococcus were collected and 78 aureus samples were isolated from Zare Hospital patients from November 2016 to July *** isolates were identified using a standard biochemical and laboratory methodology in accordance with CLSI principles,and disk agar diffusion antibiogram were performed to identify methicillin resistant *** the presence of the Panton-Valentine leukocidin gene was tested by ***:Of the methicillin-resistant Staphylococcus aureus samples,80%were negative for the Panton-Valentine leukocidin gene,and only 20%of the samples had Panton-Valentine leukocidin *** and female patients showed no significant difference in the positivity rate of Panton-Valentine leukocidin gene(16.12%vs.33.33%)(P=0.25).Besides,there was no significant difference in bacterial resistance or susceptibility to antibiotics between samples with or without the Panton-Valentine leukocidin ***:In recent years,increased resistance has been a serious *** resistance or susceptibility of Staphylococcus aureus strains to different antibiotics is different in different geographical locations.

关键词： Methicillin Resistance Panton-Valentine leukocidin PCR Staphylococcus aureus

Incorporation of 3-dimensional lycopodium with hydrophobic nature and interconnected nano-channels into polyvinylidene fluoride membranes for desalination applications by vacuum membrane distillation

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Frontiers of Chemical Science and Engineering 2023年第9期17卷 1162-1182页

作者： Saeed Seraj Toraj mohammadi maryam Ahmadzadeh Tofighy Center of Excellence for Membrane Research and Technology Department of ChemicalPetroleum and Gas EngineeringIran University of Science and Technology(IUST)Tehran***Iran

In the present research,for the first time,lycopodium as a novel nanofiller was incorporated into a polyvinylidene fluoride matrix to fabricate lycopodium/polyvinylidene fluoride flat-sheet membrane for desalination applications by vacuum membrane distillation *** prepared lycopodium/polyvinylidene fluoride membranes and lycopodium were characterized by field emission scanning electron microscopy,X-ray diffraction,Fourier transform infrared,energy dispersive X-ray,and mapping *** contact angle and liquid entry pressure measurements were also *** surface methodology was applied to optimize membrane structure and *** optimized lycopodium/polyvinylidene fluoride membrane exhibits superior performance compared to the neat polyvinylidene fluoride membrane in terms of flux,salt rejection,water contact angle,and *** vacuum membrane distillation experiments,using a 15000 ppm NaCl solution as a feed at 70℃,the neat polyvinylidene fluoride membrane,optimum membrane,and agglomerated membrane(with high lycopodium loading)demonstrated 3.80,25.20,and 14.83 LMH flux and 63.30%,99.99%,99.96%salt rejection,*** improvement in flux and salt rejection of the optimized membrane was related to the presence of lycopodium with hydrophobic nature and interconnected nano-channels in membrane *** was found that lycopodium,as the most hydrophobic material,effectively influences the membrane performance and structure for membrane distillation applications.

关键词： lycopodium hoprobhobicity vucuum embrane distillation desalination

Experimental measurement and correlation of solubility of β-carotene in pure and ethanol-modified subcritical water

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Chinese Journal of Chemical Engineering 2020年第10期28卷 2620-2625页

作者： Hadi Share mohammadi Ali Haghighi As maryam Khajenoori Faculty of Chemical Petroleum and Gas EngineeringSemnan UniversitySemnan 35131-19111Iran

For the first time,the solubility ofβ-carotene in pure and ethanol-modified subcritical water(SW)using the static method was *** experimental runs were performed at a temperature ranging from 298.15 to 403.15 K and 0–10%(w/w)of ethanol as a modifier at a constant pressure of 5 *** were analyzed by UV–vis *** solubility ofβ-carotene was found to range from 1.084×10^-8 to 227.1×10^-8 mol fractions in the subcritical water in above mentioned *** obtainedβ-carotene solubility data were correlated using the linear model and modified Apelblat *** obtained results showed the modified Apelblat model was better for estimating the solubility ofβ-carotene in *** values of the rootmean-square deviation(RMSD)between experimental and correlated data were calculated and used as the index of validity and accuracy for the ***,thermodynamic properties of the solution such as the Gibbs free energy of solution,enthalpy,and entropy of solution were estimated.

关键词： Subcritical water β-Carotene Solubility Semi-empirical model

Theoretical Study of Stability and Electronic Characteristics in Various Complexes of Psoralen as an Anticancer Drug in Gas Phase,Water and CCl_(4) Solutions

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Chemical Research in Chinese Universities 2022年第6期38卷 1414-1424页

作者： mohammadi Marziyeh MAHINIAN maryam KHANmohammadi Azadeh Department of Chemistry Faculty of ScienceVali-e-Asr University of RafsanjanP.O.Box:77176RafsanjanIran Department of Chemistry Payame Noor UniversityP.O.Box:19395-3697TehranIran

The present research employs density functional theory(DFT)computations to analyze the structure and energy of complexes formed by psoralen drug with alkali(Li^(+),Na^(+),K^(+))and alkaline earth(Be^(2+),Mg^(2+),Ca^(2+))metal *** computations are conducted on M06-2X/aug-cc-pVTZ level of theory in the gas phase and *** Atoms in Molecules(AIM)and natural bond orbital(NBO)analyses are applied to evaluating the characterization of bonds and the atomic charge distribution,*** results show that the absolute values of binding energies decrease with going from the gas phase to the ***,the considered complexes in the water(as a polar solvent)are more stable than the CCl_(4)(as a non-polar solvent).The DFT based chemical reactivity indices,such as molecular orbital energies,chemical potential,hardness and softness are also *** outcomes show that the considered complexes have high chemical stability and low reactivity from the gas phase to the ***,charge density distributions and chemical reactive sites of a typical complex explored in this study are obtained by molecular electrostatic potential surface.

关键词： Psoralen Cation-π Density function theory(DFT) Atoms in Molecules(AIM) Natural bond orbital(NBO)

Goal programming approach for sustainable forest management(case study in Iranian Caspian forests)

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Journal of Forestry Research 2014年第2期25卷 429-435页

作者： Soleiman mohammadi Limaei maryam Seddigh Kouhi Teymour Rostami Sharaji Department of Forestry Faculty of Natural ResourcesUniversity of Guilan

We used a goal programming technique to determine the optimal harvest volume for the Iranian Caspian forest. We collected data including volume, growth, wood price at forest roadside, and variable harvesting costs. The allometric method was used to quantify seques- trated carbon. Regression analysis was used to derive growth models. Expected mean price was estimated using wood price and variable harvesting costs. Questionnaire was used to determine the constraints and the equation coefficients of the goal programming model. The optimal volume was determined using the goal programming method according to multipurpose forest management. LINGO software was used for analysis. Results indicated that the optimum volumes of species were 250.25 ***-1 for beech, 59 ***-1 for hornbeam, 73 ***-1 for oak, 41 ***-1 for alder, and 32 ***-1 for other species. The total optimum volume is 455.25 ***-1.

关键词： goal programming sustainable forest management carbon sequestration Iranian Caspian forests

Nanoemulsified Mentha piperita and Eucalyptus globulus oils exhibit enhanced repellent activities against Anopheles stephensi

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Asian Pacific Journal of Tropical Medicine 2019年第11期12卷 520-527页

作者： Rahman mohammadi Mehdi Khoobdel maryam Negahban Solmaz Khani Health Research Center Life Style InstituteBaqiyatallah University of Medical SciencesTehranIran Iranian Research Institute of plant protection TehranIran Faculty of Agriculture Department of Plant ProtectionUniversity of TabrizTabrizIran

Objective:To formulate nanoemulsion from essential oils of Mentha(M.)piperita *** Eucalyptus(E.)globulus *** to compare their repellant activity with normal essential oils and N,N-diethyl-m toluamide(DEET)as a standard chemical ***:In this study,protection time of essential oils and DEET was evaluated on four human subjects using test cage,and their values were determined against Anopheles ***,ED50 values for the above essential oils were determined using the ASTM E951-94 *** compositions of essential oils were determined using GC-MS,and droplet size and zeta potential of the nanoemulsion were measured with dynamic light ***:The results(expressed as mean±SD)showed that protection time of *** 50%,*** Nano 50%,*** 50%,*** Nano 50%,and DEET 25%was(2.89±0.45)h,(4.17±0.28)h,(0.96±0.27)h,(5.51±0.02)h,and(6.10±0.47)h,***50 values were 29.10(95%CI:23.36-36.06)μg/cm^2 for Mentha,19.39(15.35-23.99)μg/cm^2 for Mentha Nano,36.10(28.70-48.01)μg/cm^2 for Eucalyptus,18.50(14.65-23.23)μg/cm^2 for Eucalyptus Nano,and 3.62(2.68-4.55)μg/cm^2 for DEET,*** Nano and *** Nano provided significantly longer protection than normal essential oils *** and ***(P<0.01).Conclusions:The preparation of nanoemulsion from the essential oils of *** and ***,significantly increases the protection time and reduces ED50 values of these essential oils,hence,*** Nano and *** Nano can be good alternatives to DEET and other chemical compounds.

关键词： Essential oil N,N-diethyl-m toluamide Nanoemulsion Eucalyptus Mentha Mosquito repellent