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Integrative multi-platform meta-analysis of hepatocellular carcinoma gene expression profiles for identifying prognostic and diagnostic biomarkers

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Genes & Diseases 2023年第4期10卷 1194-1196页

作者： maryam Gholizadeh Morteza Hadizadeh Seyed Reza Mazlooman Saeid Eslami Sadegh Raoufi Marziye Farsimadan maryam Rashidifar Marek Drozdzik Mehrnaz Mehrabani Department of Medical Informatics Faculty of MedicineMashhad University of Medical SciencesMashhad 91388-13944Iran Physiology Research Center Institute of NeuropharmacologyKerman University of Medical SciencesKerman ***Iran Department of Computer Engineering Central Tehran BranchIslamic Azad UniversityTehran ***Iran Modeling in Health Research Center Institute for Futures Studies in HealthKerman University of Medical SciencesKerman ***Iran Department of Biology Faculty of SciencesUniversity of GuilanRasht 13111-41937Iran Department of Plant Biotechnology Faculty of Life Science and BiotechnologyShahid Beheshti UniversityTehran 198396-3113Iran Department of Experimental and Clinical Pharmacology Pomeranian Medical UniversitySzczecin 70-111Poland

Hepatocellular carcinoma(HCC),as one of the most com-mon types of primary liver cancer(PLV),accounts for approximately 75%e90%of all PLV cases identified worldwide.^(1)Currently,the most effective treatment for HCC patients constitutes liver ***,due to high rates of recurrence a poor prognosis is predicted.^(2)Therefore,accurate HCC biomarkers are ur-gently needed to develop innovative *** of earlier investigations to identify biomarkers have been severely limited by sample size.

关键词： liver prognosis hepatocellular

Human-Animal Interactions in Disaster Settings:A Systematic Review

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International Journal of Disaster Risk Science 2023年第3期14卷 369-381页

作者： Haorui Wu Lindsay K.Heyland Mandy Yung maryam Schneider School of Social Work Faculty of HealthDalhousie UniversityHalifaxNS B3H 4R2Canada Department of Psychology Mount Saint Vincent UniversityHalifaxNSB3M2J6Canada

This systematic review aimed to assess the current knowledge of human-animal interactions(HAIs)in disaster settings and identify areas for future research.A Preferred Reporting Items for Systematic Reviews and Meta-Analyses search was conducted on three multidisciplinary databases,identifying English-language journal articles published between January 2000and February 2022 that explored the benefits of and challenges associated with HAI in disasters and *** review analyzed 94 articles using both quantitative and qualitative *** review found a paucity of universal terminology to describe the bidirectional relationship between humans and animals during disasters and a failure to include all animal types in every stage of disaster and emergency ***,research predominantly focused on the health and well-being benefits of HAI for humans rather than *** to promote social and environmental justice for humans and their co-inhabitants should support the welfare of both humans and animals in disaster *** recommendations were developed based on these findings to increase the inclusion of HAI in research,policy,and *** of the review included the exclusion of pre-2000 articles and all grey literature,limited research examining different combinations of animal and disaster types,and limited research outside of North America.

关键词： Emergency management Hazards and disaster research Human-animal bonds Human-animal interactions Human-animal welfare Inclusive Literature review

Major depressive disorders in patients with inflammatory bowel disease and rheumatoid arthritis

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World Journal of Clinical Cases 2023年第4期11卷 764-779页

作者： maryam Bilal Haider Brinda Basida Jasleen Kaur Department of Internal Medicine Detroit Medical CenterWayne State UniversitySinai Grace HospitalDetroitMI 48235United States Department of Geriatrics Rohde Island Hospital/Brown UniversityProvidenceRI 02903United States Department of Rheumatology St.Mary’s Ascension/Central Michigan UniversitySaginawMI 48601United States

BACKGROUND Various immune-mediated inflammatory diseases consisting of inflammatory bowel disease(IBD)and rheumatoid arthritis(RA),are found to have a substantial societal burden,increased healthcare costs,and progressive *** suggest that patients with vs without comorbid depression have a more significant disability,a lower likelihood of remission,and reduced adherence to *** interleukin(IL)-1β,tumor necrosis factor-α,and IL-6 contribute to developing depression by the impaired physiological responses to stress,resulting in increased pain,fever,fatigue,and lack thereof of interest,and thus poor long-term *** study emphasizes the timely recognition of the prevalence of major depressive disorder(MDD)in patients with RA and IBD combined,thus preventing *** To identify the prevalence level and temporal trends of depression in hospitalized IBD-RA *** All adult hospitalized patients from January 2000 to December 2019 in the nationwide inpatient sample(NIS)were *** study population included all patients with a primary or secondary IBD-RA overlap disease using corresponding international classification of diseases(ICD)-9 and ICD-10 *** includes Crohn’s disease and ulcerative *** study population was divided into IBD-RA without MDD(controls)and IBD-RA with MDD(cases).For group comparison between MDD vs no MDD,we used Student’s t-test for continuous variables and RaoScott Chi-square tests for categorical *** univariate analyses,we used logistic regression,and for multivariate analysis,we used a weighted multi-level mixed-effects *** attested all hypotheses with two-tailed significance level of 0.05(P<0.05 was considered significant).The outcome is to examine the temporal trends and prevalence of depression in patients with IBD-RA by gender,race,and *** A total of 133315 records were identified with IBD-RA overlap,of which 26155 patients(19.62%)had *** the IBD-RA

关键词： Inflammatory bowel disease Rheumatoid arthritis Depression Multimorbidity Epidemiology Demographics

A Wide Neighborhood Interior-Point Method for Cartesian P_(∗)(κ)-LCP over Symmetric Cones

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Journal of the Operations Research Society of China 2015年第3期3卷 331-345页

作者： Marzieh Sayadi Shahraki Hossein Mansouri maryam Zangiabadi Department of Applied Mathematics Faculty of Mathematical SciencesShahrekord UniversityP.O.Box 115ShahrekordIran

this paper,we propose an infeasible-interior-point method,based on a new wide neighborhood of the central path,for linear complementarity problems over symmetric cones with the Cartesian P_(∗)(κ)-*** convergence is shown for commutative class of search ***,we analyze the algorithm and obtain the complexity bounds,which coincide with the best-known results for the Cartesian P_(∗)(κ)-*** numerical tests are reported to illustrate our theoretical results.

关键词： Infeasible-interior-point method Symmetric cone optimization P_(∗)(κ)-property Wide neighborhood

A solvent-free synthesis of 1,2,3,5-tetrasubstituted pyrroles from enaminones and α-haloketones

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Chinese Chemical Letters 2011年第10期22卷 1219-1222页

作者： Issa Yavari maryam Ghazvini Leila Azad Tayebeh Sanaeishoar Department of Chemistry Science and Research BranchIslamic Azad UniversityTehranIran

A simple synthesis of 1,2,3,5-tetrasubstituted pyrrole derivatives from the reaction of enaminone withα-haloketones,under solvent-free conditions,is described.

关键词： 1H-Pyrrole Enaminone ar-Haloketone 1 3-Dicarbonyl compound Solvent-free

Spatial variability of soil development indices and their compatibility with soil taxonomic classes in a hilly landscape: a case study at Bandar village, Northern Iran

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山地科学学报（英文） 2016年第10期13卷 1746-1759页

作者： maryam OSAT Ahmad HEIDARI Mostafa KARIMIAN EGHBAL Shahla MAHMOODI Soil Science Department Agriculture and Natural Resources College University Of Tehran Soil Science Department College of Agriculture Tarbiat Modares University

Soil complexity and its multivariable nature restrict the precision of soil maps that are essential tools for soil sustainable management. Most methods developed for reducing impurities of soil map units focus on soil external properties. Taking into account the soil internal properties like geochemical weathering indices could increase the map unit's purity. However, the compatibility of these indices with Soil Taxonomic Classes has not been studied yet. This study has been performed in a hilly region with different soil types, vegetation and diverse topographic attributes to illustrate the spatial variability of soil weathering indices and their compatibility with Soil Taxonomic Classes. The grid sampling is at 100 m interval. Physico-chemical and total elemental analyses were performed on 184 and 56 soil samples respectively. Eight topographic attributes and 14 common soil development indices were determined. Principal components analysis(PCA) was done to identify the most important components. The results indicated that Morphological Index(MI) was the best index to show the degree ofsoil development in the studied region. Spatial distribution of Soil Taxonomic Classes showed relatively good compatibility with the first principal component(PC1), Vogt(V) and morphological indices. This study showed that using soil development indices with the conventional methods could be helpful tools in soil survey investigations.

关键词： Soil formation Spatial variability Weathering Topographic attributes

Improved Method for the Total Synthesis of Azaperone and Investigation of Its Electrochemical Behavior in Aqueous Solution

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Chemical Research in Chinese Universities 2022年第2期38卷 546-551页

作者： Mohammad Javad TAGHIZADEH maryam Saleh MOHAMMADNIA Masoumeh GHALKHANI Esmail SOHOULI Department of Chemistry Faculty of ScienceUniversity of Imam HosseinTehranIran Drug Applied Research Center Tabriz University of Medical SciencesTabrizIran Electrochemical Sensors Research Laboratory Department of ChemistryFaculty of ScienceShahid Rajaee Teacher Training UniversityLavizanP.O.Box ***TehranIran Young Researchers and Elites Club Science and Research BranchIslamic Azad UniversityTehranIran

Azaperone,with anti-anxiety and anti-aggressive activities used in veterinary medicine,is a member of the butyrophenone *** is ordinarily utilized for a wide range of indications,such as sedation,obstetrics,and *** this research,an improved synthetic route is presented for azaperone using a phase-transfer catalyst(PTC).In general,it was synthesized as a dopamine antagonist in four *** bis(2-chloroethyl)amine intermediate is easily obtained after the conversion of the alcohol groups into the chloride leaving group using thionyl chloride(95%yields).The alkylation of commercially available 2-amino pyridine in the presence of PTC was then carried out,giving 1-(pyridin-2-yl)piperazine with 75%yield.1-(Pyridin-2-yl)piperazine was finally alkylated using 4-chloro-1-(4-fluorophenyl)butan-1-one to achieve azaperone with 60%*** butyrophenone intermediate was obtained via the Friedel-Crafts reaction of fluorobenzene with 4-chlorobutyryl chloride in the presence of *** efficiency,gentle reaction conditions,and fast and simple procedure are the advantages of this ***,the electrochemical oxidation behaviour of azaperone was investigated using cyclic and differential pulse voltammetry *** voltammetric studies indicated an irreversible process for azaperone electro-oxidation with a peak potential of 0.78 V in a phosphate buffer solution(pH=7.0)***/AgCl(saturated KCl)*** value of the peak current *** azaperone concentration was enhanced linearly in the range of 10―70μmol/L,and the detection limit was found to be 3.33μmol/L.

关键词： Azaperone Anesthetic drug Chemical synthesis Butyrophenone class Electrochemical behavior

Melamine-formaldehyde resin supported H^+:A mild and inexpensive reagent for synthesis of coumarins under mild conditions

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Chinese Chemical Letters 2011年第11期22卷 1313-1316页

作者： Ramin Rezaei Leila Dorosty maryam Rajabzadeh Reza Khalifeh Department of Chemistry Firoozabad Branch Islamic Azad UniversityP.O.Box 74715-117 FiroozabadIran Department of Chemistry Faculty of Basic Sciences ShirazUniversity of TechnologyShiraz71555-313Iran

Melamine-formaldehyde resin supported H~＋ is used as an efficient catalyst in the Pechmann condensation reaction of phenols withβ-ketoesters,in solvent-free media leading to the formation of coumarin derivatives usi... 详细信息

关键词： Coumarins Phenols β-Ketoesters Melamine-formaldehyde resin Pechmann condensation Solvent-free

Corrosion and wear resistance of coatings produced on AZ31 Mg alloy by plasma electrolytic oxidation in silicate-based K2TiF6 containing solution:Effect of waveform

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Journal of Magnesium and Alloys 2022年第9期10卷 2574-2587页

作者： maryam Rahmati Keyvan Raeissi Mohammad Reza Toroghinejad Amin Hakimizad Monica Santamaria Department of Materials Engineering Isfahan University of TechnologyIsfahan 84156-83111Iran Yekta Mobaddel Pars Co. Science and Technology CampusYazd UniversityYazd 89158-18411Iran Dipartimento di Ingegneria Università di PalermoViale Delle ScienzeEd.690128PalermoItaly

In this research,plasma electrolytic oxidation coatings were prepared on AZ31 Mg alloy in a silicate-based solution containing K_(2)TiF_(6) using bipolar and soft sparking waveforms with 10,20,and 30%cathodic duty *** coatings displayed a net-like surface morphology consisted of irregular micro-pores,micro-cracks,fused oxide particles,and a sintered *** to the incorporation of TiO_(2) colloidal particles and the cathodic pulse repair effect,most of the micro-pores were ***-term corrosion performance of the coatings was investigated using electrochemical impedance spectroscopy during immersion in 3.5 wt.%NaCl solution up to 14 *** coating grown by the soft sparking waveform with a 20%cathodic duty cycle having the lowest porosity(6.2%)and a sharp layer concentrated in F element at the substrate/coating interface shows the highest corrosion *** friction coefficient of this coating has remained stable during the sliding even under 5 N normal load,showing relatively higher wear resistance than other *** coating produced using the equivalent unipolar waveform,as the reference specimen,showed the highest friction coefficient and the lowest wear resistance despite its highest micro-hardness.

关键词： Plasma electrolytic oxidation Pulsed waveforms AZ31 Mg alloy Dipotassium titanium hexafluoride Corrosion resistance Wear resistance