检索结果-南通市图书馆

中国科技教育 2013年第1期 10-12页

作者： anne Scott mary Whitehouse Chris Otter 陈彧(翻译) 约克大学科学教育组中国科协”做中学”科学教育实验项目教学中心(东南大学)

研究显示，学生眼中的好老师是这样的：能创造井然有序的学习环境；解释学生要做的事情并帮助他们完成；友好，能给予学生支持（Kyriacou，2009）。我们知道，一个好的教师应当具备的关键品质包括：

关键词：教师专业发展教与学课程设计科学学生支持学习环境老师

Safety and Tolerability of Edivoxetine for Long-Term Treatment of Major Depressive Disorder in Adult Patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Psychiatry 2014年第2期4卷 131-140页

作者： Tina M. Oakes James M. Martinez mary anne Dellva Celine Goldberger Beth A. Pangallo Mark E. Bangs Jonna Ahl William B. White Eli Lilly and Company Indianapolis USA University of Connecticut School of Medicine Farmington USA

This 12-month open-label, but dose-blinded extension phase, evaluated the safety and tolerability of flexibly-dosed edivoxetine (6, 9, 12 or 18 mg once daily) in patients (N = 397) with major depressive disorder, who completed the 10-week randomized, double-blind, placebo-controlled acute phase of the *** patients were treated with edivoxetine during the extension phase. The mean age of the patients was 45 years, and most were white females. Safety evaluations included assessment of treatment-emergent adverse events (TEAEs), laboratory and vital sign measures, and suicidality. Within-group t-tests based on a 2-sided significance level of 0.05 and 95% confidence levels were used to assess whether changes from baseline were statistically significant from zero. The overall completion rate was 54%. Adverse event was the most common (14.4%) reason for discontinuation, which included blood pressure increased (1.3%), heart rate increased (1.3%), anxiety (1.0%), and tachycardia (1.0%). At least 1 TEAE was reported by 72.3% of patients, of which headache (10.8%) and hyperhidrosis (10.1%) were the most common;2.8% of patients had ≥1 serious adverse events, and there were no completed suicides. No clinically relevant changes were observed in most laboratory measures. Potentially clinically significant changes in ALT values occurred in 1.8% of patients, and either normalized or had decreased by the last assessment. Mean increases in blood pressure and pulse were consistent with those observed in the acute phase and appeared to reach a plateau within 3 to 5 months of treatment. In conclusion, safety and tolerability findings during this long-term extension phase evaluation of edivoxetine were consistent with its norepinephrine reuptake inhibition profile.

关键词： Edivoxetine Norepinephrine Major Depressive Disorder Safety Tolerability

The face of conservation responding to a dynamically changing world

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2015年第5期10卷 436-452页

作者： Ruscena WIEDERHOLT anne M.TRAINOR Nicole MICHEL Patrick D.SHIREY Ronald R.SWAISGOOD Doug TALLAMY Susan C.COOK-PATTON School of Natural Resources and the Environment University of ArizonaTucsonArizonaUSA School of Forestry and Environmental Studies Yale UniversityNew HavenConnecticutUSA and The Nature ConservancyArlingtonVirginiaUSA School of Environment and Sustainability University of SaskatchewanSaskatchewanCanada R.A.Smith National OakmontPennsylvaniaUSA Division of Applied Animal Ecology San Diego Zoo Institute for Conservation ResearchCaliforniaUSA Department of Entomology and Wildlife Ecology University of DelawareNewarkDelawareUSA American Association for Advancement of Science WashingtonDCUSA

In its 40-year history,the science of conservation has faced unprecedented challenges in terms of environmental damage and rapid global change,and environmental problems are only increasing as greater demands are placed on limited natural *** science has been adapting to keep pace with these ***,we highlight contemporary and emerging trends and innovations in conservation science that we believe represent the most effective responses to biodiversity *** focus on specific areas where conservation science has had to adjust its approach to address emerging threats to biodiversity,including habitat destruction and degradation,climate change,declining populations and invasive *** also document changes in attitudes,norms and practices among conservation scientists.A key component to success is engaging and maintaining public support for conservation,which can be facilitated through the use of *** recent trends in conservation and management are innovative and will assist in optimizing conservation strategies,increasing our leverage with the general public and tackling our current environmental challenges.

关键词： global change management strategies paradigm shifts public engagement trends in conservation science

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

anne of Green Gables

Anne of Green Gables

Use of Perovskite-Type Lanthanum Nickelate Synthesized by the Polymeric Precursor Method in the Steam Reforming Reaction of Methane

作者： L.M. Montgomery edited by mary Henley Rubio and Elizabeth Waterston.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Materials Sciences and Applications 2012年第6期3卷 363-368页

作者： Daniele M.H.Martinelli Dulce M.A.Melo anne M.Garrido Pedrosa Antonio E.Martinelli Marcus A.de F.Melo mary K.S.Batista Roberto C.Bitencourt Department of Chemistry Federal University of Rio Grande do NorteCCETNatalBrazil Department of Chemistry Federal University of SergipeCCETSao CristóvaoBrazil Research Center Petrobras—Cenpes Rio de JaneiroBrazil

In the current work, LaNiO3 perovskite was synthesized using the polymeric precursor method. The materials were thermally treated at 300°C for 2 hours, subsequently supported on alumina or zirconia and finally calcined at 800°C for 4 hours. The resulting samples were characterized by X-ray diffraction, thermogravimetry, BET surface area and thermo-programmed reduction. Steam reforming reactions were carried out at 750°C and 6 bar during 4 hours using a pilot reactor under a H2O:CH4 ratio of 2.5. The mass of catalysts was about 5.7 g. X-ray diffraction patterns confirmed the formation of the perovskite structure in all samples prepared. The results also showed that lanthanum nickelate was more efficient when supported on alumina than zirconia. Finally, it was observed that the methane conversion was approximately 94% and the selectivity to hydrogen was about 70%. In all cases low selectivity to CO and CO2 was verified.

关键词： Lanthanum Nickelate Perovskite Polymeric Precursor Method Steam Reforming Reaction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

阿纳纳斯新社区规划

城市建筑 2017年第12期14卷 118-123页

作者： Dennis Pieprz Victor Eskinazi mary anne Ocampo Justin Garrison Lachlan Hicks Ponnapa Prakkamakul Anthony Fettes Lin Ye Zi Gu Sasaki事务所

阿纳纳斯新社区代表了一种大胆的推崇菲律宾农业、社会文化以及生态传承特色的城市发展方向。这种新的视野在不断变幻的城市地区背景下孕育了一种生态系统，它能够积极推动地区食品供给系统的可持续发展。通过保留社区在当地的作用和其... 详细信息

阿纳纳斯新社区代表了一种大胆的推崇菲律宾农业、社会文化以及生态传承特色的城市发展方向。这种新的视野在不断变幻的城市地区背景下孕育了一种生态系统，它能够积极推动地区食品供给系统的可持续发展。通过保留社区在当地的作用和其作为“马尼拉食物篮”的特性，吸取菲律宾重要的传统元素，为阿纳纳斯新社区提供一种全新的城市生活模式。

关键词：社区规划城市发展方向生态系统可持续发展社会文化城市地区供给系统传统元素

A phase 1b randomized clinical trial of CT1812 to measure Aβoligomer displacement in Alzheimer’s disease using an indwelling CSF catheter

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Translational Neurodegeneration 2023年第1期12卷 568-571页

作者： Kelsie M.LaBarbera Yvette I.Sheline Nicholas J.Izzo Carla M.Yuede Lora Waybright Raymond Yurko Hannah M.Edwards Woodrow D.Gardiner Kaj Blennow Henrik Zetterberg anne Börjesson-Hanson Roger Morgan Charles S.Davis Robert J.Guttendorf Lon S.Schneider Steven DeKosky Harry LeVine III Michael Grundman Anthony O.Caggiano John R.Cirrito Susan M.Catalano mary E.Hamby Cognition Therapeutics Inc. PittsburghPAUSA University of Pennsylvania PhiladelphiaUSA Washington University St.LouisUSA University of Gothenburg MölndalSweden Department of Psychiatry and Neurochemistry Institute of Neuroscience and PhysiologyThe Sahlgrenska Academy at the University of GothenburgMölndalSweden Clinical Neurochemistry Laboratory Sahlgrenska University HospitalMölndalSweden Department of Neurodegenerative Disease UCL Institute of NeurologyQueen SquareLondonUK UK Dementia Research Institute at UCL LondonUK Hong Kong Center for Neurodegenerative Diseases Clear Water BayHong KongChina Wisconsin Alzheimer’s Disease Research Center University of Wisconsin School of Medicine and Public HealthUniversity of Wisconsin-MadisonMadisonWIUSA Karolinska University Hospital StockholmSweden MedSurgPI LLCRaleighNCUSA CSD Biostatistics Inc.Oro ValleyAZUSA Aclairo Pharmaceutical Development Group IncViennaVAUSA Keck School of Medicine of USC Los AngelesCAUSA McKnight Brain Institute University of FloridaGainesvilleFLUSA Sanders-Brown Center on Aging University of KentuckyLexingtonKYUSA Global R&D Partners LLCSan DiegoCAUSA Department of Neurosciences University of CaliforniaSan DiegoUSA

Trial Registration:May 11th,2018 *** Identifier:NCT03522129 https://clini caltr ***/ct2/show/*** therapies for Alzheimer’s disease(AD)target a wide range of mechanisms,yet promising dis-ease-modifying therapies remain a huge unmet *** evidence indicates that the oligomeric form of amyloid-beta(Aβ)is a toxic species contributing to AD through synaptic damage and neuronal toxicity[1].

关键词： Alzheimer Aβ damage

韧性构想:基于社会生态学的菲律宾马尼拉大都会区城市设计

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

景观设计学（中英文） 2018年第4期6卷 98-114页

作者：斯蒂芬.F.格雷玛丽.安妮.奥坎普田乐王胤瑜 48 Quincy Street Gund Hall Cambridge MA 02138 USA

尽管城市韧性议题日益受到重视,但其理论研究仍大多局限于各学科范围内。本文以马尼拉大都会区为例,通过引入一种协调人类、自然与空间韧性的社会生态学设计方法实现韧性理论研究与实践的桥接,这里的"韧性"是指:由若干能够在不同时空维... 详细信息

尽管城市韧性议题日益受到重视,但其理论研究仍大多局限于各学科范围内。本文以马尼拉大都会区为例,通过引入一种协调人类、自然与空间韧性的社会生态学设计方法实现韧性理论研究与实践的桥接,这里的"韧性"是指:由若干能够在不同时空维度上预测并消解干扰的网络、系统与群体叠加而成的、基于特定场地和具体领域的复合体系,其具有在社会、生态和空间上实现新的平衡态的能力。这一概念包含了自然、人类和空间系统,并以历史研究、田野调查和实地走访等实证研究为依托。菲律宾政府正在实施向城外迁移人口以降低城市脆弱性的计划,对此,研究团队提出了三个城市韧性提升原则,试图通过整合正规和非正规社区来实现社会公平和生态和谐。这些原则包括:设计结合自然,而非抵抗自然;支持共享经济;致力于打破城市开发中的隔离现状。

关键词：韧性社会生态城市设计非正规性马尼拉大都会区