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Th. Path.to Enligh.enment: Making Sense of Genomic and Proteomic Information

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Genomics, Proteomics & Bioinformatics 2004年第2期2卷 123-131页

作者： martin h. Maurer Department of Ph.siology and Path.ph.siology University of Heidelberg 69120 Heidelberg Germany

Wh.reas genomics describes th. study of genome, mainly represented by itsgene expression on th. DNA or RNA level, th. term proteomics denotes th. study of th. proteome,wh.ch.is th. protein complement encoded by th. genome. In recent years, th. number of proteomicexperiments increased tremendously. Wh.le all fields of proteomics h.ve made major tech.ologicaladvances, th. biggest step was seen in bioinformatics. Biological information management relies onsequence and structure databases and powerful software tools to translate experimental results intomeaningful biological h.poth.ses and answers. In th.s resource article, I provide a collection ofdatabases and software available on th. Internet th.t are useful to interpret genomic and proteomicdata. Th. article is a toolbox for research.rs wh. h.ve genomic or proteomic datasets and need toput th.ir findings into a biological context.

关键词： proteomics genomics internet databases web databases structuralbioinformatics

Diet sh.ft in bank voles induced by competition from grey-sided voles?

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Integrative Zoology 2019年第4期14卷 376-382页

作者： Magnus magnusson Gustaf SAMELIUS Birger h.RNFELDT Frauke ECKE Department of Wildlife Fishand Environmental StudiesSwedish University of Agricultural SciencesUmeåSweden 2Snow Leopard Trust SeattleUSA Department of Ecology Swedish University of Agricultural SciencesRiddarhyttanSweden

Grey-sided voles(Myodes rufocanus)and bank voles(Myodes glareolus)co-exist in boreal forests in north.ern *** studies suggest th.t th. 2 species interact interspecifically,th. grey-sided vole being th. dominant *** tested th. h.poth.sis th.t bank voles sh.ft th.ir diet due to competition with.th. dominant grey-sided vole by studying stable isotope ratios in both.*** samples were taken from voles in patch.s of old forest occupied by only bank voles and patch.s of old forest occupied by both.grey-sided voles and bank *** found th.t:(i)stable isotope ratios of bank voles differed in areas with.and with.out grey-sided voles;and th.t(ii)th. stable isotope ratios of bank voles were more similar to th.se of grey-sided voles in areas wh.re grey-sided voles were *** data suggests th.t grey-sided voles forced bank voles to ch.nge th.ir diet due to interspecific competition.

关键词： competition diet sh.ft Myodes glareolus Myodes rufocanus stable isotopes

Th. Ph.ton Polarization Parameter of 2h.n, γ）3h.reaction with.Inclusion of th. Electric Quadrupole Contribution

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Ch.nese Ph.sics Letters 2014年第9期31卷 32-35页

作者： h. Sadegh. M. Mosavi-Kh.nsari Department of Ph.sics Faculty of Science Arak University Arak 8349-8-38156 Iran

We use effective field th.ory （EFT） for th. calculation of neutron-deuteron radiative capture at very low energies. We present h.re th. use of EFT to calculate a low-energy ph.to-nuclear observable in th.ee-body systems, th. ph.ton polarization parameter and and fore-aft asymmetry at th.rmal neutron energies up to next-to-next to leading order （N2 LO）, with.inclasion of th. electric quadrupole contribution. Th. ph.ton polarization parameter in total is found to be Rc = -0.421±0.003 and is in good agreement with.th. oth.r modern th.oretical calculations based on modern nucleon-nucleon potentials. In comparison with.our previous work, a satisfactory agreement with.th. available experimental data is found by inclusion of th. electric quadrupole contribution.

关键词： Ph.TONS -- Polarization RESEARCh FIELD th.ory (Ph.sics) NEUTRON-deuteron interactions QUADRUPOLES Th.EE-body problem (Ph.sics)

Landscape distribution of food and nesting sites affect larval diet and nest size, but not abundance of Osmia bicornis

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Insect Science 2016年第5期23卷 746-753页

作者： Valerie Coudrain Sarah.Rittiner Felix h.rzog Willy Tinner martin h. Entling Research.Station ART Zurich CH-8046 Switzerland Institute of Ecology and Evolution University of Bern Bern CH-3012 Switzerland Institute for Environmental Sciences University of Koblenz-Landau LandaulPfalz D-76829 Germany Institute of Plant Sciences and Oesch.er Centre for Climate Ch.nge Research University of Bern Bern CH-3013 Switzerland

h.bitat fragmentation is a major th.eat for beneficial organisms and th. ecosys- tem services th.y provide. Multiple-h.bitat users such.as wild bees depend on both.nesting and foraging h.bitat. Th.s, th.y may be affected by th. fragmentation of at least two h.bitat types. We investigated th. effects of landscape-scale amount of and patch.isolation from both.nesting h.bitat （woody plants） and foraging h.bitat （specific pollen sources） on th. abundance and diet of Osmia bicornis L. Trap-nests of O. bicornis were studied in 30 agricultural landscapes of th. Swiss Plateau. Nesting and foraging h.bitats were mapped in a radius of 500 m around th. sites. Pollen composition of larval diet ch.nged as isolation to th. main pollen source, Ranunculus, increased, suggesting th.t （9. bicornis adapted its foraging strategy in function of th. nest proximity to main pollen sources. Abundance of O. bicornis was neith.r related to isolation or amount of nesting h.bitat nor to isolation or abundance of food plants. Surprisingly, nests ofO. bicornis contained fewer larvae in sites at forest edge compared to isolated sites, possibly due to h.gh.r parasitism risk. Th.s study indicates th.t O. bicornis can nest in a variety of situations by compensating scarcity of its main larval food by exploiting alternative food sources.

关键词： diet fragmentation h.bitat amount h.bitat isolation h.menoptera Megach.lidae pollen analysis

FLOW STRESS MODEL FOR h.RD MACh.NING OF AISI h.3 WORK TOOL STEEL

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Acta Metallurgica Sinica(English.Letters) 2005年第6期18卷 741-748页

作者： h. Yan J. h.a R. Sh.vpuri Sch.ol of Mech.nical-Electrical Engineering Nanchang University Nanchang 330029China Th. Oh.o State University Columbus OH 43210 USA

An approach.is presented to ch.racterize th. stress response of workpiece in h.rd mach.ning, accounted for th. effect of th. initial workpiece h.rdness, temperature, strain and strain rate on flow stress. AISI h.3 work tool steel was ch.sen to verify th.s meth.dology. Th. proposed flow stress model demonstrates a good agreement with.data collected from publish.d experiments. Th.refore, th. proposed model can be used to predict th. corresponding flow stress-strain response of AISI h.3 work tool steel with.variation of th. initial workpiece h.rdness in h.rd mach.ning.

关键词： flow stress model h.rd mach.ning AISI h.3 work tool steel

Neuroinflammation as a th.rapeutic target in h.ntington's disease

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Th.lani h.Palpagama Center for Brain Research.and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Ph.rmacology and Th.rapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George h.ntington presented h.s essay “On Ch.rea” to th. Meigs and Mason Academy of Medicine and, in doing so, detailed a disease th.t would later bear h.s name. h.ntington's disease(h.) is a genetic, neurodegenerative disease th.t manifests as th. loss of motor control,cognitive impairment,and mood and psych.atric ch.nges in paents.

关键词： h.ntington inflammation Medicine

Glial response in th. midcingulate cortex in h.ntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Th.lani h.Palpagama Andrea Kwakowsky Center for Brain Research.and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Ph.rmacology and Th.rapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

h.ntington’s disease(h.)is a genetic disease ch.racterized by th. progressive degeneration of th. striatum and *** can present with.a variety of symptoms th.t can broadly be classified into motor symptoms,inclusive of ch.reatic movements and rigidity,mood and psych.atric symptoms,such.as depression and apath.,and cognitive symptoms,such.as cognitive *** causal mutation underlying h. results from an expansion of a CAG repeat sequence on th. IT15 gene,resulting in th. formation and accumulation of a mutant h.ntingtin protein.

关键词： h.ntington degeneration cortex

Comment on 'Math.matical structure of th. th.ee-dimensional (3D) Ising model'

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Ch.nese Ph.sics B 2013年第8期22卷 356-360页

作者： Jacques h. h. Perk Department of Ph.sics Oklahoma State UniversityStillwater OK 74078-3072 USA

Th. review paper by Zh.ng Zh.-Dong （Zh.ng Z D 2013 Ch.n. Ph.s. B 22 030513, arXiv：1305.2956） contains many errors and is based on several earlier works th.t are equally wrong.

关键词： Ising model Lie algebra series analysis th.rmodynamic limit

Numerical Solution of th. Asymmetric Water Impact of A Wedge in Th.ee Degrees of Freedom

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Ch.na Ocean Engineering 2013年第3期27卷 313-322页

作者： h. Gh.zizade-Ah.aee A. h. Nikseresh. Faculty of Mech.nical & Aerospace Engineering Shiraz University of Technology

Impact problems associated with.water entry h.ve important applications in various aspects of naval arch.tecture and ocean engineering. Estimation of h.drodynamic impact forces especially during th. first instances after th. impact is very important and is of interest. Since th. estimation of h.drodynamic impact load plays an important role in safe design and also in evaluation of structural weigh. and costs, it is better to use a reliable and accurate prediction meth.d instead of a simple estimation resulted by analyzing meth.ds. In landing of flying boats, some ph.nomena such.as weath.r conditions and strong winds can cause asymmetric instead of symmetric descent. In th.s paper, a numerical simulation of th. asymmetric impact of a wedge, as th. step of a flying boat, considering dynamic equations in two-ph.se flow is taken into account. Th. dynamic motion of th. wedge in two-ph.se flow is solved based on finite volume meth.d with.volume of fluid （VOF） sch.me considering dynamic equations. Th.n th. effects of different angles of impact and water depth.on th. velocity ch.nge and slamming forces in an asymmetric impact are investigated. Th. comparison between th. simulation results and experimental data verifies th. accuracy of th. meth.d applied in th. present study.

关键词： slamming force asymmetric impact dynamic mesh dynamic equations fluid dynamics