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RNA and Protein Requirements for Eukaryotic Selenoprotein Synthesis

Biomedical and Environmental Sciences 1997年第2期10卷 182-189页

作者： MARLA J. BERRY GLOVER W. martin Ⅲ, AND SUSAN C. LOW(Thyroid Division, Department of Medicine, Brigham and Women’s Hospital Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts 02115,USA) Department of Medicine Brigham and Women's Hospital Boston Massachusetts USA.

Selenium has been recognized as an essential nutrient in animals since the 1950s. Demonstration of the role of dietary selenium in protection from oxidative stress foIlowed in the early 1970s, and was largely attributed to its presence as an integral part of cellular glutathione peroxidase. However, the functions of this enzyme did not explain many of the other effects of selenium deficiency. The identification of other mammalian selenoproteins during the last few years has provided new insights into the functions of this trace nutrient. The discovery that type 1 deiodinase (D1) is a selenoenzyme, in addition to unveiling an essential role for selenium in thyroid hormone action, has had more far-reaching implications. Studies of this protein opened the door for investigation of the requirements for eukaryotic selenoprotein synthesis,and the features that distinguish this pathway from the corresponding prokaryotic *** is present in a number of prokaryotic and eukaryotic proteins in the form of the unusual amino acid, selenocysteine. Incorporation of selenocysteine into these proteins requires a novel translation step in which UGA specifies selenocysteine insertion. Since UGA codons are typically recognized as translation stop signals, an intriguing question is raised: How does a cell recognize and distinguish a UGA selenocysteine codon from a UGA stop codon? In this review, we will focus on what is known about selenocysteine incorporation in eukaryotes, briefly summarizing initial studies and discussing a few recent advances in our understanding of this unique 'recoding' process

关键词： RNA and Protein Requirements for Eukaryotic Selenoprotein Synthesis UGA

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Elimination of Carbon, Nitrogen and Phosphorus in Domestic Wastewater through a Series of Anaerobic and Aerobic Reactors for a Developing Country like Benin

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American Journal of Analytical Chemistry 2015年第7期6卷 577-584页

作者： Senandemi E. R. Mahunon Akuemaho V. O. Akowanou martin P. Aina Benjamin K. Yao Dominique K. C. Sohounhloué Laboratoire des Sciences et Techniques de l’Eau (LSTE) Université d’Abomey-Calavi (UAC) Cotonou Benin Laboratoire de Procédés Industriels de Synthèse de l’Environnement et des Energies Nouvelles Institut National Polytechnique Félix Houphou&euml t-Boigny de Yamoussoukro Yamoussoukro C&ocirc te d’Ivoire Laboratoire d’Etude et de Recherche en Chimie Appliquée (LERCA) Ecole Polytechnique d’Abomey-Calavi (EPAC) Université d’Abomey-Calavi (UAC) Cotonou Bénin

Waste water treatment in order to preserve water resources is one of the major concerns in developing countries. This study aims to test the operating effectiveness of a pilot designed on a basis of several laboratory experiments, which consists of an anaerobic and aerobic pond in series. The test was performed through monitoring global parameters of pollution. The results of the analysis of these parameters indicate an elimination of 91% of suspended solids, 68% of COD, 77% of BOD5, 61% of nitrate and 81% of phosphorus. It was also noticed that the anaerobic pond removes most, carbonaceous organic materials and especially suspended matters;and the aerobic pond most, nitrogen and especially phosphorus. This study reveals the effectiveness of the series connection of an anaerobic and aerobic pond for domestic wastewater treatment.

关键词： Wastewater Anaerobic/Aerobic Pond Pilot

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Recovery Capacity, Haemodynamic and Blood Lactate Changes during Training and Competition in Elite Congolese Karate Athletes

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World Journal of Cardiovascular Diseases 2020年第5期10卷 257-273页

作者： Jean Georges André Moulongo Jean martin Moussoki Elvina Lys Surêche Massamba Fêtra Nella Massala Kitanga Bernard Packa Tchissambou Jean Robert Mabiala Babela Alphonse Massamba Laboratory of Sport Biosciences and Combat Sports Research Unit Higher Institute of Physical Education and Sports Marien NGOUABI University Brazzaville Congo Laboratory “Health and Adapted Physical Activities” Higher Institute of Physical Education and Sports Marien NGOUABI University Brazzaville Congo Pediatrics Department Brazzaville University Hospital and Faculty of Health Sciences Marien NGOUABI University Brazzaville Congo

Background: Rare are the studies which treated the effect of training and successive fights of karate on haemodynamic and blood lactate concentrations responses. Objectives: To evaluate and analyze the aerobic capacity of elite Congolese karate athletes, as well as their haemodynamic and blood lactate concentrations responses changes during Ruffier test and stimulated competition. Methods: Twelve karate athletes (6 seniors and 6 juniors) took part in the study. These karate athletes were selected within the national karate teams (senior and junior) of Congo-Brazzaville. Anthropometric, bioenergetic and haemodynamic (HR, SBP, DBP) parameters and blood lactate [La] concentrations were measured at rest, immediately after the end of Ruffier test and each fight (n = 3). Results: Peak aerobic power (PAP) and maximum oxygen uptake (VO2 max) values averaged 437 ± 23 watts and 57.61 ± 2.2 ml/kg/mn, values varying as function as age division (senior vs junior). The recovery index was 5.4 ± 3.4 for juniors and 6.8 ± 3.2 for seniors. SBP, HR and [La] concentrations increased significantly during fights, compared to the resting values. HRmax was 182.3 ± 1.6 bpm (89% theoretical HRmax) for seniors and 182.0 ± 13.5 bpm (86% theoretical HRmax) for juniors. Peak [La] concentrations were 10.3 ± 1.5 mmol/l for seniors and 10.8 ± 1.2 mmol/l for juniors. Conclusion: Congolese karate athletes call upon high levels of the anaerobic and aerobic capacities. The karate training program in Congo should emphasize more gold improvising lower body anaerobic power and endurance.

关键词： Karate Peak Aerobic Power Maximum Oxygen Uptake Heart Rate Blood Lactate

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习得性无助

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作者： (美)马丁·塞利格曼(martin E. P. Seligman)

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Preface

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Journal of Computer Science & Technology 2012年第6期27卷 1091-1091页

作者： Ralph R. martin School of Computer Science & Informatics Cardiff University U.K.

With the rapid development of various technologies from the Internet to mobile phones and cameras, visual data is now widely available in huge quantity and great variety, bringing significant opportunities for novel w... 详细信息

关键词： Preface CVM

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Python贝叶斯分析

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作者： (阿根廷)奥斯瓦尔多·马丁(Osvaldo martin)

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Cadaveric bone marrow mesenchymal stem cells:first experience treating a patient with large severe burns

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Burns & Trauma 2015年第2期3卷 74-82页

作者： Eduardo Mansilla Gustavo H.Marín Mirta Berges Silvia Scafatti Jaime Rivas Andrea Núñez martin Menvielle Roberto Lamonega Cecilia Gardiner Hugo Drago Flavio Sturla Mercedes Portas Silvia Bossi Maria Victoria Castuma Sandra Peña Luengas Gustavo Roque Karina Martire Jose Maria Tau Gabriel Orlandi Adrian Tarditti Tissue Engineering Regenerative Medicine and Cell Therapies LaboratoryCUCAIBAProvince of Buenos Aires Ministry of HealthTransplantation ProgramLa PlataProvince of Buenos AiresArgentina Burns and Plastic Surgery Department San Martín HospitalProvince of Buenos Aires Ministry of HealthLa PlataProvince of Buenos AiresArgentina Burns Hospital Buenos Aires CityArgentina Department of Chemistry Mayaguez CampusUniversity of Puerto RicoMayaguezPuerto RicoUSA.

Background:In January 2005,Rasulov et *** published"First experience in the use of bone marrow mesenchymal stem cells(MSCs)for the treatment of a patient with deep skin burns".Here,we present the first ever treated patient with cadaveric bone marrow mesenchymal stem cells(CMSCs)in the history of ***:A young man,who severely burned 60%of his total body surface with 30%of full-thickness burns while working with a grass trimmer that exploded,was involved in the *** were obtained from the bone marrow of a cadaver donor in a routine procurement procedure of CUCAIBA,the Province of Buenos Aires,Argentina,Ministry of Health,Transplantation Agency,cultured,expanded,and applied on the burned surfaces using a fibrin spray after early ***:So far,our preliminary experience and our early results have been very impressive showing an outstanding safety data as well as some impressive good results in the use of ***:Based on al this,we think that improvements in the use of stem cells for burns might be possible in the near future and a lot of time as well as many lives could be saved by many other research teams all over the *** will probably be a real scientific opportunity in Regenerative Medicine as well as in Transplantation.

关键词： Burns Cadaveric Transplantation Skin regeneration Mesenchymal stem cells

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宝洁制胜战略

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作者： (美)雷富礼(A.G. Lafley) (美)罗杰·马丁(Roger L. martin)

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冰与火之歌

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作者： (美)乔治 R·R·马丁(George R. R. martin)

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INTERNATIONAL SOCIETY FOR VETERINARY EPIDEMIOLOGY AND ECONOMICS

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中国微生态学杂志 1991年第1期3卷 55-55页

作者： S.Wayne martin Secretary International Management Committee

This letter is to announce the sixth meeting of the International Society of Veterinary Epidemiology and Economics which will be held in Ottawa,Canada,August 10-16th, 1991. We have chosen Carleton University as the physical location of the meeting. At that time of year, it provides very good meeting rooms,eating facilities and lodging for a price that will allow us to keep registration and related costs at reasonable levels. For those

关键词： announce facilities registration sixth eating letter chosen Canada costs concurrent

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