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Embracing different languages and local differences:Coconstructive patient simulation strengthens host countries’clinical training in psychiatry

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World Journal of Psychiatry 2024年第1期14卷 111-118页

作者： Şafak ErayÇamlı Büşra Ece Yavuz Meliha Feyza Gök Idil Yazgan Yanki Yazgan Ayelet Brand-Gothelf Doron Gothelf Doron Amsalem Andrés martin Department of Child and Adolescent Psychiatry Bursa UludağUniversity Faculty of MedicineBursa 16059 Turkey Yale University School of Medicine New HavenCT 06510United States Güzel Günler Clinic Beşiktaş/İstanbul 34335 Turkey Child Study Center Yale School of MedicineNew HavenCT 06520United States The Feinberg Child Study Center Schneider Children's Medical Center of IsraelTel Aviv UniversityPetach Tikvah 4920235Israel The Child Psychiatry Division Edmond and Lily Safra Children’s HospitalSheba Medical CenterTel HashomerRamat Gan 52561Israel Faculty of Medicine and Sagol School of Neuroscience Tel Aviv UniversityTel Aviv 6997801Israel Department of Psychiatry Columbia University Vagelos College of Physicians and SurgeonsNew YorkNY 10032United States

BACKGROUND Global education in psychiatry is heavily influenced by knowledge from Western,high-income countries,which obscures local voices and *** To adapt a human simulation model to psychiatric education in a context that is specific to local languages and *** We conducted an observational study consisting of six human simulation sessions with standardized patients from two host countries,speaking their native languages,and following an adaptation of the co-constructive patient simulation(CCPS)*** local faculty became increasingly familiar with the CCPS approach,they took on the role of facilitators—in their country’s native *** Fifty-three learners participated:19 child and adolescent psychiatry trainees and 3 faculty members in Türkiye(as a group that met online during 3 consecutive months);and 24 trainees and 7 faculty in Israel(divided into 3 groups,in parallel in-person sessions during a single training day).Each of the six cases reflected local realities and clinical challenges,and was associated with specific learning goals identified by each case-writing *** Human simulation has not been fully incorporated into psychiatric education:The creation of immersive clinical experiences and the strengthening of reflective practice are two areas ripe for *** adaptations of CCPS can also strengthen local and regional networks and psychiatric communities of ***,the model can help question and press against hegemonies in psychiatric training that overshadow local expertise.

关键词： Human simulation Standardized patients Medical education Psychiatric education Capacity building Local languages

Projected near-surface wind speed and wind energy over Central Asia using dynamical downscaling with bias-corrected global climate models

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Advances in Climate Change Research 2024年第4期15卷 669-679页

作者： Jin-Lin ZHA Ting CHUAN Yuan QIU Jian WU De-Ming ZHAO Wen-Xuan FAN Yan-Jun LYU Hui-Ping JIANG Kai-Qiang DENG Miguel ANDRES-martin Cesar AZORIN-MOLINA Deliang CHEN Key Laboratory of Atmospheric Environment and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunming 650091China Key Laboratory of Regional Climate and Environment for Temperate East Asia Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China Center for Energy&Environmental Policy Research Beijing Institute of Technology Beijing 100081China Key Laboratory of Regional Sustainable Development Modeling Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China International Research Center of Big Data for Sustainable Development Goals Beijing 100094China School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Centro de Investigaciones Sobre Desertificacion Consejo Superior de Investigaciones Cientificas(CIDECSIC-UV-Generalitat Valenciana)ClimateAtmosphere and Ocean Laboratory(Climatoc-Lab)Moncada 46113Spain Regional Climate Group.Deparment of Earth Sciences University of GothenburgGothenburg 40530Sweden

Wind energy development in Central Asia can help alleviate drought and fragile ***,current studies mainly used the global climate models(GCMs)to project wind speed and *** simulated biases in GCMs remain prominent,which induce a large uncertainty in the projected *** reduce the uncertainties of projected near-surface wind speed(NSW)and better serve the wind energy development in Central Asia,the Weather Research and Forecasting(WRF)model with bias-corrected GCMs was *** with the outputs of GCMs,dynamical downscaling acquired using the WRF model can better capture the high-and low-value centres of NSWS,especially those of Central Asia's ***,the simulated NSWS bias was also *** future changes in wind speed and wind energy,under the Representative Concentration Pathway 4.5(RCP4.5)scenario,NSWS during 2031-2050 is projected to decrease compared with that in *** magnitude of NSwS reduction during 2031-2050 willreach 0.1 m s^(-1).and the maximum reduction is projected to occur over the central and western regions(>0.2 m s^(-1)).Furthermore,future wind power density(WPD)can reveal nonstationarity and strong volatility,although a downward trend is expected during *** addition,the higher frequency of wind speeds at the turbine hub height exceeding 3.0 m s^(-1)can render the plain regions more suitable for wind energy development than the mountains from 2031 to *** study can serve as a guide in gaining insights into future changes in wind energy across Central Asia and provide a scientific basis for decision makers in the formulation of policies for addressing climate change.

关键词： Near-surface wind speed Wind power density Dynamical downscaling Central Asia WRF

Late-onset Very long-chain acyl-CoA dehydrogenase deficiency diagnosis complicated by fulminant myocarditis in adult patient

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Journal of Intensive Medicine 2024年第3期4卷 400-402页

作者： martin Gérard Clair Douillard Julien Poissy Mehdi Marzouk Christophe Vinsonneau Intensive Care Unit Centre Hospitalier de Bethune-BeuvryBethuneFrance Endocrinology diabetologymetabolism departmentLille reference centre of inborn errors of metabolismLille University HospitalLilleFrance Inserm U1285 CHU LillePôle de réanimationCNRSUMR 8576-UGSF-Unitéde Glycobiologie Structurale et FonctionnelleUniv.LilleLilleFrance

Introduction A 21-year-old woman presented to the emergency department with fatigue,abdominal pain and *** physical activity in school was strictly *** had no family medical history and no personal history but reported frequent episodes of nausea and vomiting lasting 2 to 7 days during the past two years,as well as a weight loss of 9 kg due to reactive anorexia(Body Mass Index 17.5),without triggering factors or *** gastrointestinal symptoms led to the detection of isolated elevated transaminases(aspartate aminotransferase[AST]190 U/L and alanine aminotransferase[ALT]170 U/L);however,the patient did not pursue the proposed etiological *** has been using cannabis once a day for several years,with an increase in consumption over the past year,but no *** reported no other recent change in her habits.

关键词： diagnosis patient elevated

Movement analysis in the diagnosis and management of Parkinson’s disease

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Neural Regeneration Research 2025年第2期20卷 485-486页

作者： Johannes Burtscher Nicolas Bourdillon Jules MJanssen Daalen Aurélien Patoz Julien FBally martin Kopp Davide Malatesta Bastiaan RBloem Institute of Sport Sciences University of LausanneLausanneSwitzerland Radboud University Medical Center Department of NeurologyDonders Institute for BrainCognition and BehaviorCenter of Expertise for Parkinson and Movement DisordersNijmegenThe Netherlands Radboud University Medical Center Department of Medical BioSciencesNijmegenThe Netherlands Research and Development Department Volodalen Swiss Sport LabAigleSwitzerland Service of Neurology Department of Clinical NeurosciencesLausanne University Hospital(CHUV)and University of Lausanne(UNIL)LausanneSwitzerland Department of Sport Science University of InnsbruckInnsbruckAustria

Challenges in the diagnosis and treatment of Parkinson’s disease:Parkinson’s disease(PD)is an increasingly prevalent neurodegenerative disease,at first sight primarily characterized by motor symptoms,although non-motor symptoms also constitute a major part of the overall ***,this disease cannot be diagnosed reliably until a large part of the vulnerable dopaminergic neurons has been irretrievably lost,and the disease progresses *** biological criteria for PD have been proposed recently and might eventually improve early diagnosis,but they require further validation,and their use will initially be restricted to a research environment(Darweesh et al.,2024).

关键词： diagnosis Clinical eventually

Effect of Thermal Cycles on Creep Behavior of Bituminous Binder in Hot Regions

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Journal of Civil Engineering and Architecture 2024年第7期18卷 334-339页

作者： Bachir Glaoui Mahdjoub Bendjima M'hamed Merbouh martin Van de Ven Laboratoire de la Fiabilité des Matériaux et Structures en Régions Sahariennes(FIMAS) Université de Béchar B.P.417Béchar08000Algérie Laboratory of Road and Railway Engineering TU DelftP.O.Box 50482600 GA DelftThe Netherlands

This research is devoted to the study of creep behavior of asphalt binder in hot *** binder was subjected to thermal cycles due to the variation of temperature from day to *** cycles produce a heating-cooling *** evaluate the effect of climate change in laboratory,the DSR(dynamic shear rheometer)was used,and the results found with the nine samples were *** thermal cycles led to aging and therefore hardening of the ***,a rheological model was proposed that can represent the curves obtained experimentally,where it is able to describe the creep behavior of binders tested.A new model is proposed that correlates well with the experimental curves,which is called A+2 K.

关键词： Bitumen temperature heating/cooling DSR BBR model

A Comparison of Hydrothermal Aging, SO₂ and Propene Poisoning Effects on NH₃-SCR over Cu-ZSM-5 and Cu-SAPO-34 Catalysts

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Journal of Materials Science and Chemical Engineering 2024年第5期12卷 10-28页

作者： Kouadio Brou Albert Koffi Konan martin Zran Van Eric-Simon Horo Kone Unité de Formation et de Recherche des Sciences et de Technologies (UFR ST) Universit&#233 Alassane Ouattara Bouak&#233 C&#244te d&#8217Ivoire Unité de Formation et de Recherche Environnement (UFR E) Universit&#233 Jean Lorougnon Gu&#233d&#233 Daloa C&#244te d&#8217Ivoire Unité de Formation et de Recherche des Sciences des Structures de la Mati&#232re et de Technologie (UFR SSMT) Abidjan C&#244te d&#8217Ivoire

This study was aimed to investigate the effects of hydrothermal aging, propene and SO2 poisoning on the ammonia-selective catalytic reduction (NH3-SCR) performance of both Cu-SAPO-34 and Cu-ZSM-5. The catalytic activities of fresh, aged and poisoned samples were tested in ammonia-selective catalytic reduction (NH3-SCR) of NOx conditions. The XRD, TG and N2-desorption results showed that the structures of the Cu-SAPO-34 and Cu-ZSM-5 remained intact after 750˚C hydrothermally aged, SO2 and propene poisoned. After hydrothermal aging at 750˚C for 12 h, the NO reduction performance of Cu-ZSM-5 was significantly reduced at lower temperatures, while that of Cu-SAPO-34 was less affected. Moreover, Cu-SAPO-34 catalyst showed high NO conversion with SO2 or propene compared to Cu-ZSM-5. However, Cu-ZSM-5 showed a larger drop in catalytic activity with SO2 or propene compared to Cu-SAPO-34 catalyst. The H2-TPR results showed that Cu2 ions could be reduced to Cu and Cu0 for Cu-ZSM-5, while no significant transformation of copper species was observed for Cu-SAPO-34. Meanwhile, the UV-vis DRS results showed that CuO species were formed in Cu-ZSM-5, while little changes were observed for the Cu-SAPO-34. Cu-SAPO-34 showed high sulfur and hydrocarbon poison resistance compared to Cu-ZSM-5. In summary, Cu-SAPO-34 with small-pore zeolite showed higher hydrothermal stability and better hydrocarbon and sulfur poison resistant than Cu-ZSM-5 with medium-pore.

关键词： Hydrothermal Aging Propene and SO2Poisoning Ammonia-Selective Catalytic Reduction(NH3-SCR) Cu-SAPO-34 Cu-ZSM-5

Assessing the Impact of Gold Mining on the Quality of Water Resources in the Commune of Meguet, Burkina Faso

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Journal of Water Resource and Protection 2024年第4期16卷 281-292页

作者： Issoufou Ouedraogo Samuel Lankoande Yacouba Konate Boukary Sawadogo Nicolas Kagambega martin Lompo Higher School of Engineering (ESI) University of Fada N&#8217Gourma Fada N&#8217Gourma Burkina Faso Geosciences and Environment Laboratory (LaGE) Joseph KI-ZERBO University Ouagadougou Burkina Faso Water Hydro-Systems and Agriculture Laboratory (LEHSA) International Institute of Water and Environmental Engineering (2iE) Ouagadougou Burkina Faso

Despite its often illegal nature, artisanal gold mining in Burkina Faso contributes to the economic and social development of the country. However, the rudimentary techniques used in gold panning have a significant impact on the environment due to inappropriate practices and the use of various chemical substances. This study aims to assess the impact of artisanal gold mining on the quality of water resources in a rural community at Méguet, Burkina Faso. To this end, surface and groundwater samples were collected and analyzed at the BUMIGEB laboratory. Field results show that the waters are slightly alkaline (6.97 < pH < 8.1), weakly mineralized and conductive (124 < EC < 543 μS/cm), with temperatures ranging from 24.6˚C to 31.6˚C. In addition, trace metals (TMEs) analyzed from surface and subsurface waters show very high levels, generally deviating from the levels recommended by WHO guidelines for Burkina Faso. Trace metals contamination of water resources in the commune of Méguet is mainly due to Fe (3.78 - 11.12 mg/kg), Hg (0.03 - 0.29 mg/kg), As (0.01- 6.31 mg/kg) and Pb (0.01 - 3.8 mg/kg). This study can serve as a basis for guiding national environmental policies to protect the water resources of the Méguet mine.

关键词： Gold Panning Water Quality Trace Metal Méguet Burkina Faso

A Bioequivalence Study of Empagliflozin/Metformin Fixed-Dose Combination in Healthy Subjects under Fasting Conditions

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Journal of Biosciences and Medicines 2024年第9期12卷 235-250页

作者： Evelyn Pena Alfredo Inatti Anyoly Taly José Chacón Xenon Serrano-martin Department of Clinical Research Industrias Biocontrolled C.A. Grupo Leti S.A.V. Guarenas Venezuela Department of Research & Development Industrias Biocontrolled C.A. Grupo Leti S.A.V. Guarenas Venezuela Department of Medical Megat Laboratories Quito Ecuador

Background: This study evaluated the bioequivalence of empagliflozin 12.5 mg/metformin 1000 mg tablets compared to Synjardy® (Empagliflozin 12.5 mg/metformin 1000 mg) tablets in healthy male subjects under fasting conditions. Methods: This was a phase I, randomized, single-dose, two-period, two-sequence, crossover study to evaluate the bioequivalence (BE) profiles of two fixed-dose combinations (FDCs) of empagliflozin/metformin. Cmax, AUC0-t and AUC0-∞ from test and reference formulations were evaluated to access BE. The plasma concentrations were measured using a validated liquid chromatography-mass spectrometry (LC-MS/MS) method. Of the 24 subjects enrolled, 23 completed both periods of the study. The two formulations test and reference were considered bioequivalent if 90% confidence interval (CI) fell within 80.00% - 125.00% for Cmax, AUC0-t and AUC0-∞. Tolerability and safety were assessed throughout the study. Results: The pharmacokinetic (PK) parameters were similar between the test product (T) and reference product (R) Synjardy®. The 90% CI of the test/reference ratios of log-transformed PK parameters point estimates was Cmax: 89.87% (85.68% - 94.27%), AUC0-t: 87.91% (83.65% - 92.39%) and AUC0-∞: 87.16% (82.80% - 91.75%) to empagliflozin and Cmax: 92.19% (87.95% - 96.65%), AUC0-t: 91.38% (84.42% - 98.91%) and AUC0-∞: 93.78% (83.82% - 104.93%) to metformin respectively (90% CI for all PK parameters fell within 80.00% - 125.00%). Conclusion: Our results demonstrated BE between the test and reference formulations of oral tablets of empagliflozin 12.5 mg/metformin 1000 mg (FDC) in healthy male subjects under fasting conditions.

关键词： Bioequivalence Fix Dose Combinations Pharmacokinetic Empagliflozin

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从欧洲到中国,JUAL与防水行业共成长

中国建筑防水 2024年第8期 6-8页

作者： martin Thomsen 优尔屋面科技(苏州)有限公司江苏苏州215000

值此中国建筑防水协会成立40周年之际,JUAL(优尔)作为协会及其金属屋面分会、单层屋面分会的会员,谨向协会致以最诚挚的祝贺和美好的祝愿!回望这过去的岁月,在欧洲勤耕不辍的JUAL和在中国精业笃行的防水协会就好像两条平行线,相互陌生... 详细信息

值此中国建筑防水协会成立40周年之际,JUAL(优尔)作为协会及其金属屋面分会、单层屋面分会的会员,谨向协会致以最诚挚的祝贺和美好的祝愿!回望这过去的岁月,在欧洲勤耕不辍的JUAL和在中国精业笃行的防水协会就好像两条平行线,相互陌生、并无交集;不曾想,我们彼此仿佛有着始于地球两端冥冥中注定的缘分,终有一天会为了同一份事业奔赴而来,相聚在一起。

关键词：中国建筑防水防水行业金属屋面防水协会平行线