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程序员 2010年第9期 38-41页

作者： Alex martelli Andrew Stellman Jennifer Greene

采访手记：Google的开发工作是非常严谨的，Alex martelli作为Google的一名高级技术主管，一直从事着软件开发中最严谨的那一面工作。本文Alex介绍了Google在打造出色团队方面的成功经验。

关键词： Google 访谈录软件开发成功经验

Numerical Study of Switching Behavior in Finite Media Subject to 3D Ferroelectric-Paraelectric Interactions and Inspection of Calibration Effects

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Numerical Mathematics(Theory,Methods and Applications) 2021年第1期14卷 113-143页

作者： P.-W.martelli S.M.Mefire Universite de Lorraine CNRSIECLF-54000 NancyFrance

We study numerically the switching behavior aspects and calibration effects relative to finite media embedding fully a three-dimensional ferroelectric layer in a paraelectric *** approach makes use of the Ginzburg-Landau formalism in combination with the electrostatics *** associated discrete nonlinear system,which arises from finite element approximations,is solved by an inexact Newton *** resulting numerical experiments highlight the effects of a balance between the physical and geometrical *** particular,the same state switchings can be retrieved from different ferroelectric layer sizes by acting upon the physical characteristic of the paraelectric *** platelet samples are in parallelepipedic and cylindrical configurations involved in these experiments.

关键词： Electroactive media ferroelectricity electrostatics Ginzburg-Landau systems finite elements inexact Newton methods numerical simulations

Structural properties of water confined by phospholipid membranes

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Frontiers of physics 2018年第1期13卷 57-64页

作者： Fausto martelli Hsin-Yu Ko Carles Calero Borallo Giancarlo Franzese Department of Chemistry Princeton University Princeton NJ 08544 USA Seccio de Fisica Estadlstica i Interdisciplinaria-Departament de Fisica de la Materia Condensada Facultat de Fisica Universitat de -Barcelona Mart i Franqus 1 08028 Barcelona Spain Institute of Nanoscience and Nanotechnology (IN2UB) Universitat de Barcelona Av. Joan XXIII S/N 08028 Barcelona Spain

Biological membranes are essential for cell life and hydration. Water provides the driving force for the assembly and stability of many cell components. Here, we study the structural properties of water in a phospholipid membrane. We characterize the local structures, inspecting the intermediate range order （IRO） and adopting a sensitive local order metric recently proposed by martelli et al. that measures and grades the degree of overlap of the local environment with the structures of perfect ice. Close to the membrane, water acquires a high IRO and changes its dynamical properties; i.e., its translational and rotational degrees of freedom slow in a region that extends over - 1 nm from the membrane interface. Surprisingly, we show that at distances as far as -~ 2.5 mn from the interface, although the bulk-like dynamics are recovered, the IRO of water is still slightly higher than that in the bulk under the same thermodynamic conditions. Therefore, the water-membrane interface has a structural effect at ambient conditions that propagates further than the often-invoked 1-nm length scale. Consequently, this should be considered when analyzing experimental data of water confined by membranes and could help us to understand the role of water in biological systems.

关键词： confined water dimyristoylphosphatidylcholines DMPC order parameter

Could the improvement of obesity-related co-morbidities depend on modified gut hormones secretion?

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World Journal of Gastroenterology 2014年第44期20卷 16649-16664页

作者： Carmine Finelli Maria Carmela Padula Giuseppe martelli Giovanni Tarantino Center of Obesity and Eating Disorders Stella Maris Mediterraneum Foundation Department of Science University of Basilicata Potenza Department of Clinical Medicine and Surgery Federico Ⅱ University Medical School of Naples Centro Ricerche Oncologiche di Mercogliano Istituto Nazionale Per Lo Studio E La Cura Dei Tumori "Fondazione Giovanni Pascale" IRCCS

Obesity and its associated diseases are a worldwide epidemic disease. Usual weight loss cures- as diets, physical activity, behavior therapy and pharmacotherapy- have been continuously implemented but still have relatively poor long-term success and mainly scarce adherence. Bariatric surgery is to date the most effective long term treatment for morbid obesity and it has been proven to reduce obesity-related co-morbidities, among them nonalcoholic fatty liver disease, and mortality. This article summarizes such variations in gut hormones following the current metabolic surgery procedures. The profile of gut hormonal changes after bariatric surgery represents a strategy for the individuation of the most performing surgical procedures to achieve clinical results. About this topic, experts suggest that the individuation of the crosslink among the gut hormones, microbiome, the obesity and the bariatric surgery could lead to new and more specific therapeutic interventions for severe obesity and its co-morbidities, also non surgical.

关键词： Obesity Bariatric surgery Gut hormones Nonalcoholic fatty liver disease Microbiome

Turbine Blade Boundary Layer Separation Suppression via Synthetic Jet: an Experimental and Numerical Study

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Journal of Thermal Science 2012年第5期21卷 404-412页

作者： Bernardini C. Carnevale M. Manna M. martelli F. Simoni D. Zunino P. Università degli Studi di Firenze Firenze Italy Università degli Studi di Napoli Federico Ⅱ Napoli Italy Università degli Studi di Firenze FirenzeItaly Università degli Studi di Genova Genova Italy

The present paper focuses on the analysis of a synthetic jet device (with a zero net massflow rate) on a separated boundary layer. Separation has been obtained on a flat plate installed within a converging-diverging test section specifically designed to attain a local velocity distribution typical of a high-lift LPT blade. Both experimental and numerical investigations have been carried out. Unsteady RANS results have been compared with experiments in terms of time-averaged velocity and turbulence intensity distributions. Two different Reynolds number cases have been investigated, namely Re = 200,000 and Re = 70,000, which characterize low-pressure turbine operating conditions during take-off/landing and cruise. A range of synthetic jet aerodynamic parameters (Strouhal number and blowing ratio) has been tested in order to analyze the features of control-separated boundary layer interaction for the aforementioned Reynolds numbers.

关键词： Synthetic Jet Separated Flow Active Flow Control Unsteady Flow Ultra High Lift LPT.

Light propagation through biological tissue and other diffusive media : theory, solutions, and software

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Sexual maturity,seasonal estrus,and gestation in female Indo-Pacific bottlenose dolphins Tursiops aduncus inferred from serum reproductive hormones

1000年

作者： Fabrizio martelli et al

Includes bibliographical references and index.

ISBN: (纸本)9780819476586;0819476587

Includes bibliographical references and index.

关键词： Light Tissues

来源：畅想之星图书光盘版（南... 评论

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Integrative Zoology 2021年第4期16卷 575-585页

作者： Peijun ZHANG Zhengzhi WEI Suk-Wai HUI Grant ABEL Paolo martelli Yujiang HAO Songhai LI Marine Mammal and Marine Bioacoustics Laboratory Institute of Deep-sea Science and EngineeringChinese Academy of SciencesSanyaChina University of Chinese Academy of Sciences BeijingChina Ocean Park Hong Kong Hong Kong SARChina Seattle Aquarium SeattleWAUSA Institute of HydrobiologyChinese Academy of Sciences WuhanChina

Reproductive hormones in serum concentrations of progesterone,estradiol,and testosterone in female Indo-Pacific bottlenose dolphins(Tursiops aduncus,n=12)housed in Ocean Park Hong Kong were investigated in the present *** showed that,onset of puberty of captive Indo-Pacific bottlenose dolphins was at 5 years while sexual maturity was at *** serum progesterone concentrations in non-pregnant sexually mature individuals was 0.33(0.25–0.97)ng/mL(interquartile),significantly higher than in immature ones 0.26(0.25–0.38)ng/*** study found significant difference in serum estradiol concentrations between individuals at the onset of puberty(9.5±1.7 ng/mL,±SD)and not(below detection limit 9 pg/mL).A slightly seasonal breeding pattern,with progesterone values tend to be higher from February to October(0.38[0.25–1.07]ng/mL)was *** pregnancy,serum progesterone concentrations range from 10.54±8.74 ng/mL(indexed month post-conception[IMPC]0)to 25.49±12.06 ng/mL(IMPC 2),and display a bimodal pattern with 2 peaks in early-(25.49±12.06 ng/mL,IMPC 2)and late-pregnancy(21.71±10.25 ng/mL,IMPC 12),*** estradiol concentrations can seldom be detected in early-pregnancy and increase constantly in mid-(9.45±1.83 pg/mL)and late-pregnancy(11.88±3.81 pg/mL),with a spike(15.45±6.78 pg/mL)1 month prior to *** testosterone concentrations elevate significantly in IMPC 7(0.36±0.10 ng/mL)compared to other months(0.16±0.10 ng/mL)of the *** present study provides normal concentration profiles for some reproductive hormones in female Indo-Pacific bottlenose dolphins and can contribute to the breeding monitoring of this ***,our study would shed further light on the reproductive physiology of small cetaceans.

关键词： cetacean estradiol pregnancy progesterone testosterone

Comprehensive lumped parameter and multibody approach for the dynamic simulation of agricultural tractors with tyre–soil interaction

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IET Cyber-Systems and Robotics 2023年第3期5卷 1-23页

作者： Massimo martelli Damiano Chiarabelli Silvia Gessi Pietro Marani Emiliano Mucchi Marco Polastri Institute of Sciences and Technologies for Sustainable Energy and Mobility CNR‐STEMSNational Research CouncilFerraraItaly Department of Engineering University of FerraraFerraraItaly

Modern agricultural tractors are complex systems,in which multiple physical(and technological)domains interact to reach a wide set of competing goals,including work operational performance and energy *** complexity translates to the dynamic,multi‐domain simulation models implemented to serve as digital twins,for rapid prototyping and effective pre‐tuning,prior to bench and on‐field ***,a suitable simulation framework should have the capability to focus both on the vehicle as a whole and on individual *** each of the latter,multiple options should be available,with different levels of detail,to properly address the relevant phenomena,depending on the specific focus,for an optimal balance between accuracy and computation *** methodology proposed here by the authors is based on the lumped parameter approach and integrates the models for the following subsystems in a modular context:internal combustion engine,hydromechanical transmission,vehicle body,and tyre–soil *** model is completed by a load cycle module that generates stimulus time histories to reproduce the work load under real operating *** capability is affected by vertical load on the wheels,which is even more relevant if the vehicle is travelling on an uncompacted soil and subject to a variable drawbar pull force as it is when *** vertical load is,in turn,heavily affected by vehicle dynamics,which can be accurately modelled via a full multibody *** presented lumped parameter model is intended as a powerful simulation tool to evaluate tractor performance,both in terms of fuel consumption and traction dynamics,by considering the cascade phenomena from the wheel–ground interaction to the engine,passing through the dynamics of vehicle bodies and their mass *** capabilities and numerical results are presented for the simulation of a realistic ploughing operation.

关键词： agricultural tractor digital twin lumped parameter simulation,multibody powertrain tyre-soil interaction

Photoluminescence of CdSe Nanowires Grown With and Without Metal Catalyst

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Nano Research 2011年第4期4卷 343-359页

作者： Andrea Fasoli Alan Colli Faustino martelli Simone Pisana Ping Heng Tan Andrea C. Ferrari Department of Engineering University of Cambridge Cambridge CB3 0FA UK Nokia Research Centre Broers Building （East Forum） Cambridge CB3 0GT UK lstituto per la Microelettronica e i Microsistemi del CNR 00133 Rome Italy SKLSM Institute of Semiconductors Chinese Academy of Sciences Beijing 100083 China

We present temperature and power dependent photoluminescence measurements on CdSe nanowires synthesized via vapor-phase with and without the use of a metal catalyst. Nanowires produced without a catalyst can be optimized to yield higher quantum efficiency, and narrower and spatially uniform emission, when compared to the catalyst-assisted ones. Emission at energies lower than the band-edge is also found in both cases. By combining spatially-resolved photoluminescence and electron microscopy on the same nanowires, we show that catalyst-free nanowires exhibit a low-energy peak with sharp phonon replica, whereas for catalyst-assisted nanowires low-energy emission is linked to the presence of nanostructures with extended morphological defects.

关键词： CdSe nanowires photoluminescence

Effectiveness of BNT162b2 and CoronaVac vaccines against omicron in children aged 5 to 11 years

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World Journal of Pediatrics 2023年第10期19卷 949-960页

作者： Eduardo A.Oliveira Maria Christina L.Oliveira Ana Cristina Simões e Silva Enrico A.Colosimo Robert H.Mak Mariana A.Vasconcelos Ludmila R.Silva Daniella B.martelli Clara C.Pinhati Hercílio martelli-Júnior Department of Pediatrics Health Sciences Postgraduate ProgramSchool of MedicineFederal University of Minas Gerais(UFMG)R.Engenheiro Amaro Lanari 389/501Belo HorizonteMG30130-100Brazil Department of Statistics Federal University of Minas GeraisBelo HorizonteMGBrazil Department of Pediatrics Rady Children’s HospitalUniversity of CaliforniaLa JollaSan DiegoCAUSA Health Science/Postgraduate Program in Nursing.School of Nursing Federal University of Minas Gerais(UFMG)Belo HorizonteMG30130-100Brazil Health Science/Primary Care Postgraduate Program State University of Montes Claros(Unimontes)Montes ClarosMG39401-089Brazil

Background This study aimed to estimate vaccine effectiveness(VE)against omicron variant infection and severe corona virus disease 2019(COVID-19)in children aged 5–11 years hospitalized with acute respiratory *** A test-negative,case–control analysis was conducted from February 2022 to June *** enrolled 6950 eligible children,including 1102 cases and 5848 *** was calculated after immunization with one and two doses of BNT162b2 or *** outcomes were hospitalization with acute respiratory symptoms and detection of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection and severe *** adjusted odds ratio for the association of prior vaccination and outcomes was used to estimate *** For fully vaccinated children,the overall estimated VE against hospitalization with SARS-CoV-2 infection was 42%[95%confidence interval(CI)26 to 54].VE peaked at 29–42 days(67%,95%CI 40%to 82%)and then declined to 19%(95%CI,−20%to 45%)at 57–120 days after the second *** BNT162b2 vaccine had a similar VE against hospitalization with SARS-CoV-2 infection(45%,95%CI,20 to 61)compared to the CoronaVac vaccine(40%,95%CI,17%to 56%).Among cases,56(5%)children died;53(94.6%)were not fully *** cases,the two-dose schedule effectiveness against ICU admission,need for invasive ventilation,severe illness,and death were 10%(95%CI,−54%–45%),22%(95%CI−70%–68%),12%(95%CI,−62%–52%),and 16%(95%CI,−77%–75%),*** For hospitalized children aged 5–11 years during the omicron-predominant period in Brazil,two doses of both vaccines had moderate effectiveness against hospitalization with acute respiratory symptoms and SARS-CoV-2 infection and offered limited protection against endpoints of COVID-19 severity.

关键词： Children COVID-19 Effectiveness Omicron Vaccine