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Plateau archives of lithosphere dynamics,cryosphere and paleoclimate:The formation of Cretaceous desert basins in east Asia

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Geoscience Frontiers 2022年第6期13卷 170-181页

作者： Chihua Wu Juan pedro Rodríguez-López M.Santosh State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu 610059China PAGODA Research Group(Plateau&Global Desert Basins Research Group) Institute of Sedimentary GeologyChengdu University of TechnologyChengdu 610059China Permafrost Laboratory Department of GeographyUniversity of SussexFalmerBrighton BN19SJUnited Kingdom School of Earth Science and Resources China University of Geosciences29 Xueyuan RoadBeijing 100083China Department of Earth Sciences University of AdelaideSA 5005Australia

Southeastern Eurasia is a global window to the Cretaceous paleoclimate and lithosphere *** contains one of the most complete and complex sedimentary records of Mesozoic desert basins on planet *** this study,we perform the spatio-temporal tracking of 96 Cretaceous palaeoclimate indicators during 79 Myr which reveal that the plateau paleoclimate archives from East Asia resulted from an Early to Mid-Cretaceous ocean–atmosphere coupling and a shift to a preponderant role of Late Cretaceous lithosphere dynamics and tectonic forcing on high-altitude depositional systems linked to the subduction margins of the Tethys and Paleo-Pacific realms beneath the Eurasian *** crustal response to tectonic processes linked with the spatio-temporal evolution of the Tethyan and Paleo-Pacific margins defined the configuration of major sedimentary basins on this *** significant increase and decrease in the number of active sedimentary basins that occur during the Cretaceous,from 16 in the Early Cretaceous,to 28 in the Mid-Cretaceous,and a decreasing to 20 sedimentary basins in the Late Cretaceous,is a direct response of lithospheric dynamics associated with the two main subduction zones(Tethys and Pacific domains).A shift in subduction style from an Early Cretaceous Paleo-Pacific Plate slab roll back to a Late Cretaceous flat-slab mode might have triggered regional plateau uplift,blocked intraplate volcanism,thus enhancing the denudation and sediment availability,and created wind corridors that led to the construction and accumulation of extensive Late Cretaceous aeolian sandy deserts(ergs)that covered Mid-Cretaceous plateau *** the same time,plateau uplift associated with crustal thickening following terrane assembly in the Tethyan margin triggered altitudinal cryospheric processes in sandy desert *** of an active Cretaceous cryosphere in China include ValanginianHauterivian glacial debris flows,Early Aptian geochemical signature of melt w

关键词： Cretaceous Cryosphere Aeolian Plateau Subduction Asia

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Validation and adaptation of the Physical Activity Enjoyment Scale (PACES) in fitness group exercisers

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Journal of Sport and Health Science 2020年第4期9卷 352-357页

作者： pedro Teques Luıs Calmeiro Carlos Silva Carla Borrego N2i Polytechnic Institute of Maia Research CentreMaia 4475-690Portugal CIPER Interdisciplinary Centre for the Study of Human PerformanceCruz Quebrada 1499-002Portugal Abertay University School of Social and Health SciencesDundee DD11HGUK Polytechnic Institute of Santarem Sport Sciences School of Rio MaiorSantarem 2001-904Portugal CIEQV—Life Quality Research Center Santarem 2001-904Portugal

Background:Recently,Mullen et al.(2011)presented an 8-item version of the Physical Activity Enjoyment Scale(PACES)that provides a valid instrument for assessing enjoyment in physical *** present paper investigated the psychometric properties of a Portuguese adaptation of ***:After a process of back-to-back translation into Portuguese,395 members of fitness centers who ranged in age from 18 to 66 years(31.11§8.90,mean§SD)completed the translated version of the *** average,participants had 3.2 years of experience in fitness group classes and practiced for approximately 3.3 times per ***:An initial exploratory factor analysis(n=139)revealed a unidimensional structure with factor loadings ranging from 0.79 to *** also showed acceptable internal consistency.A confirmatory factor analysis in an independent sample(n=256)provided additional support for the unidimensional structure of the *** addition,moderate positive correlations between enjoyment and intrinsic and identified regulation,and moderate negative correlations between enjoyment and external and amotivation,demonstrate the convergent validity of the ***,measurement invariance between 2 independent samples was also ***:The 8-item Portuguese version of PACES is a valid and reliable instrument for measuring enjoyment of physical activity in Portuguese adult fitness exercisers,and it is therefore suitable to use as a measure of affect in exercise adherence interventions studies.

关键词： Confirmatory factor analysis Construct validity Enjoyment Exploratory factor analysis Fitness Measurement invariance Self-determination theory

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Pedestrian street and its effect on economic sustainability of a historical Middle Eastern city:The case of Chaharbagh Abbasi in Isfahan,Iran

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Geography and Sustainability 2023年第3期4卷 188-199页

作者： Soudabeh Shahmoradi Sayyed Mahdi Abtahi pedro Guimaraes Department of urban planning Iranian Knowledge-Based Company of Pezhvak Tarh IranianIsfahan Science and Technology TownIsfahan University of Technology BlvdIsfahanIran Department of Civil Engineering Isfahan University of TechnologyIsfahanIran Centre of Geographical Studies Associated Laboratory TERRAInstitute of Geography and Spatial PlanningLisboaPortugal

Pedestrianization is an urban revitalization strategy to enhance sustainability and livability in car-oriented *** many studies in this research field,the effects of pedestrianization on the economy of cities in developing countries still need further ***,the impact of this strategy on the tenant mix of com-mercial and historical areas in Middle East countries is *** address these inadequacies,we considered Chaharbagh Abbasi street,located in the heart of Isfahan,Iran,and investigated the impact of a pedestrianization project with particular emphasis on how it affects the economic sustainability of existent commercial ***-and post-project data along with field observations and quantifications used to assess structural replacements in trade,were analyzed with SPSS and ArcGIS *** results revealed unexpected outcomes,such as the closure of some traditional businesses(27.5%),a stagnation in sales(69%)and a decrease in job offers(84%)leading the local economy to a fragile ***,it was found that the footfall volume increased by 64% and 73% from the retailers’and pedestrians’*** evolution along with a wide opening of food and beverage stores(approximately 60%)makes the post-pedestrianization results more promising than earlier *** conclusion,these findings reinforce the importance of pedestrian streets in revitalizing economic activities in historical and commercial areas from the perspective of economic *** to the lack of similar investigations in Middle East countries,these findings can support decision-makers and urban planners to take preventive measures in preserving the diversity of individual small shops for upcoming urban rehabilitation projects in terms of pedestrianization.

关键词： Urban planning Pedestrianization Chaharbagh abbasi Sustainable Development Goals(SDGs) Economic sustainability Historic city centers

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Pacing profiles and tactical behaviors of elite runners

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Journal of Sport and Health Science 2021年第5期10卷 537-549页

作者： Arturo Casado Brian Hanley pedro Jimenez-Reyes Andrew Renfree Faculty of Health Sciences Isabel I UniversityBurgos 09003Spain Carnegie School of Sports Leeds Beckett UniversityLeeds LS63QSUK Centre for Sport Studies Rey Juan Carlos UniversityMadrid 28943Spain Institute of Sport and Exercise Science University of WorcesterWorcester WR26AJUK

The pacing behaviors used by elite athletes differ among individual sports,necessitating the study of sport-specific pacing ***,pacing behaviors adopted by elite runners differ depending on race ***“all-out”strategy,characterized by initial rapid acceleration and reduction in speed in the later stages,is observed during 100 m and 200 m events;400 m runners also display positive pacing patterns,which is characterized by a reduction in speed throughout the ***,800 m runners typically adopt a positive pacing strategy during paced“meet”***,during championship races,depending on the tactical approaches used by dominant athletes,pacing can be either positive or negative(characterized by an increase in speed throughout).A U-shaped pacing strategy(characterized by a faster start and end than during the middle part of the race)is evident during world record performances at meet races in 1500 m,5000 m,and 10,000 m *** a parabolic J-shaped pacing profile(in which the start is faster than the middle part of the race but is slower than the endspurt)can be observed during championship 1500 m races,a negative pacing strategy with microvariations of pace is adopted by 5000 m and 10,000 m runners in championship *** cross country and marathon championship races are characterized by a positive pacing strategy;whereas a U-shaped pacing strategy,which is the result of a fast endspurt,is adopted by 3000 m steeplechasers and half *** contrast,recent world record marathon performances have been characterized by even pacing,which emphasizes the differences between championship and meet races at distances longer than 800 *** reviewed suggest further recommendations for *** the whole race,800 m runners should avoid running wide on the *** turn,during major championship events,1500 m,5000 m,and 10,000 m runners should try to run close to the inside of the track as much as possible during t

关键词： Athletics Distance running Pacing Sprinting

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Effects of Imazethapyr-Based Herbicide Formulation in the Zebrafish (Danio rerio) Hepatocyte Cell Line (ZF-L): Cytotoxicity and Oxidative Stress

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Journal of Environmental Protection 2024年第6期15卷 747-765页

作者： Edila Maria Kickhöfel Ferrer Milena Mattes Cerveira pedro Henrique Flores Da Cruz Cleiton Jesus Andrade Pereira Lucas Moraes Berneira Claudio Martin Pereira de Pereira Nathalia Stark Pedra Roselia Maria Spanevello Jean Carlos Bauer Vieira Clarissa Piccinin Frizzo Mateus Tavares Kütter Janice Luehring Giongo Rodrigo de Almeida Vaucher Center of Chemical Pharmaceutical and Food Sciences Microorganism Biochemistry and Molecular Biology Research Laboratory (LAPEBBIOM) Federal University of Pelotas (UFPEL) Pelotas Rio Grande do Sul Brazil Center of Chemical Pharmaceutical and Food Sciences Laboratory for Lipidomic and Bio-Organic Research Bioforensic Research Group Federal University of Pelotas (UFPEL) Pelotas Rio Grande do Sul Brazil Center of Chemical Pharmaceutical and Food Sciences Neurochemistry Inflammation and Cancer Laboratory Federal University of Pelotas (UFPEL) Pelotas Rio Grande do Sul Brazil Department of Chemistry Heterocycle Chemistry Center (NUQUIMHE) Federal University of Santa Maria (UFSM) Santa Maria Rio Grande do Sul Brazil Department of Microbiology and Parasitology Biology Institute Federal University of Pelotas (UFPEL) Pelotas Rio Grande do Sul Brazil

Seizures of agrochemical formulations have increased in Brazil and Rio Grande do Sul is among the Brazilian states with the highest number of seizures of these products obtained illicitly. The use of illicit formulations can cause significant harm to agricultural production, the environment, and non-target species. This study evaluated the cytotoxicity and oxidative stress of a seized formulation containing the herbicide imazethapyr (IMZT). Characterization of the herbicide included gas chromatography-mass spectrometry (GC-MS) and thermal analyses (thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)). Hemolytic and cytotoxicity assays in ZF-L hepatic cells showed IC50 values of 12.75 µg/mL, 3.01 µg/mL, 2.67 µg/mL, and 1.61 µg/mL for erythrocytes, [3(4,5-dimethyl)-2 bromide-5 diphenyl tetrazolium] (MTT), neutral red (NR), and lactate dehydrogenase (LDH) assays, respectively. The median IC50 of 2.84 µg/mL was used in oxidative stress assays, revealing increased reactive oxygen species (ROS) production, reduced total sulfhydryl content, and decreased superoxide dismutase (SOD) and catalase (CAT) activity. This study is the first to report in vitro oxidative stress induced by IMZT in the ZF-L cell line, emphasizing the importance of in vitro assays for assessing the toxic effects of seized agrochemicals on human health and the environment.

关键词： Agrochemical Imidazolinone Zebrafish Cell Viability Oxidative Damage

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Bilateral hip heterotopic ossification with sciatic nerve compression on a paediatric patient–An individualized surgical approach: A case report

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World Journal of Orthopedics 2022年第8期13卷 768-774页

作者： João pedro Gouveia Nóbrega pedro Jordão Joana Arcângelo Department of Orthopaedics Hospital Dr.Nélio MendonçaFunchal 9000-243Portugal Department of Orthopaedics Hospital Dona EstefâniaLisboa 1169-045Portugal

BACKGROUND Neurogenic heterotopic ossification is an acquired serious complication described in patients with central nervous system disorders and defined by bone formation in non-osseous *** SUMMARY We present an unusual case of a 13-yr-old boy presenting with hip pain and severe gait impairment 5 mo after the diagnosis of hemiplegia following a spontaneous intracerebral *** tomography revealed bilateral heterotopic ossification of both the paretic and the non-paretic limbs,with entrapment of the sciatic *** choice of surgical or nonsurgical management of such patients depends on the timing of diagnosis,the symptoms,and the extent of maturation of the ossified *** resection remains the only treatment with proven,evidence-based *** choice of surgical approach largely depends on the location of the ossified *** We believe the plane of dissection presented is a satisfactory option for resection of a posteromedial mass and sciatic nerve release.

关键词： Hip Heterotopic ossification Pediatrics Orthopedics Ressection surgery Case report

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Testing the hypothesis of subtypes of nonadherence in schizophrenia and schizoaffective disorder:A prospective study

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World Journal of Psychiatry 2020年第11期10卷 260-271页

作者： Dulcinea Vega Francisco J Acosta pedro Saavedra Department of Psychiatry University of Las Palmas de Gran CanariaLas Palmas de Gran Canaria 35016Las PalmasThe Canary IslandsSpain Department of Psychiatry Insular University Hospital Department of Mental Health General Management of Healthcare Programs Canary Islands Health ServiceLas Palmas de Gran Canaria 35004Las PalmasThe Canary IslandsSpain Research Network on Health Services for Chronic Conditions(REDISSEC) Carlos III Health InstituteMadrid 28029Spain Department of Mathematics University of Las Palmas de Gran CanariaLas Palmas de Gran Canaria 35016Las PalmasThe Canary IslandsSpain

BACKGROUND Nonadherence is a major problem in the treatment of psychotic *** has been hypothesized that nonadherent patients with schizophrenia are not a homogeneous population and subtypes of nonadherence might exist,but this hypothesis has not been specifically *** To test the hypothesis of subtypes of nonadherence in schizophrenia and schizoaffective *** This prospective study included 110 consecutively admitted patients diagnosed with schizophrenia or schizoaffective *** were performed at baseline and at 6 mo follow-up after ***,clinical,psychopathological and treatment-related variables were *** was defined as the concurrence of adherence to antipsychotic treatment and outpatient follow-up during the six-month *** to antipsychotic treatment was defined as the concurrence of objective and subjective ***-four patients(58%)fulfilled nonadherence criteria at the end of the followup period and were categorized according to their subtype of *** In nonadherent patients(n=64),32(50%)fulfilled criteria of intentional nonadherence,and 32(50%)of unintentional nonadherence(UNA).Unintentional nonadherent patients,as compared to intentional nonadherent patients,are characterized by older age,lower educational level,worse cognitive and negative symptoms,greater severity,worse knowledge of their treatment regimen,greater prevalence of supervision of the treatment,lower number of prior hospitalizations and greater use of nonpsychiatric treatment,anticholinergics and *** educational level(OR=26.1;95%CI:2.819-241),worse treatment knowledge at six months(OR per unit=0.904;95%CI:0.853-0.957)and nonpsychiatric treatment at six months(OR=15.8;95%CI:1.790-139)were independently associated to *** Differentiated subtypes of nonadherence according to intentionality seem to exist in patients with schizophrenia and schizoaffective ***

关键词： Adherence Hospitalization Psychosis Hypothesis Unintentional nonadherence Intentional nonadherence

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Beacon-Less Geographic Routing in Real Wireless Sensor Networks

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Journal of Computer Science & Technology 2008年第3期23卷 438-450页

作者： Juan A.Sánchez Rafael Marín-Pérez pedro M.Ruiz Department of Information and Communications Engineering University of MurciaSpain

Geographic Routing （GR） algorithms require nodes to periodically transmit HELLO messages to allow neighbors to know their positions （beaconing mechanism）. Beacon-less routing algorithms have recently been proposed to reduce the control overheads due to these messages. However, existing beacon-less algorithms have not considered realistic physical layers. Therefore, those algorithms cannot work properly in realistic scenarios. In this paper we present a new beacon-less routing protocol called BOSS. Its design is based on the conclusions of our open-field experiments using Tmote-sky sensors. BOSS is adapted to error-prone networks and incorporates a new mechanism to reduce collisions and duplicate messages produced during the selection of the next forwarder node. We compare BOSS with Beacon-Less Routing （BLR） and Contention-Based Forwarding （CBF） algorithms through extensive simulations. The results show that our scheme is able to *** almost perfect packet delivery ratio （like BLR） while having a low bandwidth consumption （even lower than CBF）. Additionally, we carried out an empirical evaluation in a real testbed that shows the correctness of our simulation results.

关键词： geographic routing beacon-less forwarding performance evaluation real deployment

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Mining Gene Expression Profiles:An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decomposition

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Genomics, Proteomics & Bioinformatics 2010年第3期8卷 200-210页

作者： Ferran Reverter Esteban Vegas pedro Sánchez Department of Statistics Faculty of BiologyUniversity of Barcelona

The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualization tools are used to identify genes with similar profiles in microarray studies. Given the large number of genes recorded in microarray experiments, gene expression data are generally displayed on a low dimensional plot, based on linear methods. However, microarray data show nonlinearity, due to high-order terms of interaction between genes, so alternative approaches, such as kernel methods, may be more appropriate. We introduce a technique that combines kernel principal component analysis （KPCA） and Biplot to visualize gene expression profiles. Our approach relies on the singular value decomposition of the input matrix and incorporates an additional step that involves KPCA. The main properties of our method are the extraction of nonlinear features and the preservation of the input variables （genes） in the output display. We apply this algorithm to colon tumor, leukemia and lymphoma datasets. Our approach reveals the underlying structure of the gene expression profiles and provides a more intuitive understanding of the gene and sample association.

关键词： kernel method biplot gene expression profile dimension reduction

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Degradative solvent extraction of subbituminous coal with deep eutectic solvent and effect of reaction conditions on products

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Carbon Resources Conversion 2023年第1期6卷 43-50页

作者： pedro Domingos Dauce Ryo Suzuki Ayano Nakamura Kenji Murakami Department of Material Science Graduate School of Engineering ScienceAkita University1-1 Tegata Gakuen-tyoAkita-shiAkita 010-8502Japan

A degradative solvent extraction method for upgrading low-rank coal was performed at 200-350◦C for 90 min to obtain a substance dissolved in the solvent at room temperature(Soluble).Because the resulting mixture exhibited a high carbon content without ash,it could be readily used as a ***,deep eutectic solvents(DESs)have attracted attention for improving the Soluble yield and decreasing the oxygen content in *** is known to cleave oxygen-containing functional groups in biomass and is considered effective for deoxidizing low-rank ***,DES was prepared by mixing choline chloride,FeCl3⋅6H2O,and Adaro subbituminous coal(AD)and then added to 1-methylnaphthalene(1-MN)in a non-polar solvent,followed by degradative solvent extraction in the range of 200-350◦*** effects of reaction temperature and added DES amount on the product yield and the composition were *** the reaction temperature and amount of DES added increased,the Soluble yield and carbon content *** was also found that the thermal decomposition temperature and oxygen content decreased with the increasing DES *** decrease indicates that DES promotes the deoxygenation and decomposition of AD and increases the soluble yield of the fuel source.

关键词： Low-rank coal Degradative solvent extraction Deep eutectic solvent Reaction temperature Upgrading

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