检索结果-南通市图书馆

Role of gut microbiota in cardiovascular diseases

World Journal of Cardiology 2020年第4期12卷 110-122页

作者： marko novakovic Amit Rout Thomas Kingsley Robert Kirchoff Amteshwar Singh Vipin Verma Ravi Kant Rahul Chaudhary Department of Internal Medicine Sinai Hospital of BaltimoreBaltimoreMD 21215United States Department of Internal Medicine Division of Hospital Internal MedicineMayo ClinicRochesterMN 55905United States Department of Internal Medicine Division of Hospital MedicineJohns Hopkins University School of MedicineBaltimoreMD 21205United States Department of Internal Medicine Medical University of South Carolina/AnMed CampusCharlestonSC 29425United States Division of Endocrinology Diabetes and NutritionMedical University of South Carolina/Anmed CampusAndersonSC 29621United States

The human gut is colonized by a community of microbiota,primarily bacteria,that exist in a symbiotic relationship with the *** microbiota-host interactions play a critical role in the regulation of human *** changes to the composition of gut microbiota,referred to as gut dysbiosis,has been linked to the development and progression of numerous diseases,including cardiovascular disease(CVD).Imbalances in host-microbial interaction impair homeostatic mechanisms that regulate health and can activate multiple pathways leading to CVD risk factor *** CVD risk factors,including aging,obesity,dietary patterns,and a sedentary lifestyle,have been shown to induce gut *** is associated with intestinal inflammation and reduced integrity of the gut barrier,which in turn increases circulating levels of bacterial structural components and microbial metabolites,including trimethylamine-N-oxide and short-chain fatty acids,that may facilitate the development of *** article reviews the normal function and composition of the gut microbiome,mechanisms leading to the leaky gut syndrome,its mechanistic link to CVD and potential novel therapeutic approaches aimed towards restoring gut microbiome and CVD *** CVD is the leading cause of deaths globally,investigating the gut microbiota as a locus of intervention presents a novel and clinically relevant avenue for future research.

关键词： Cardiovascular disease Coronary artery disease Gut microbiota Dysbiosis Thrombosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：