检索结果-南通市图书馆

Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue

World Journal of Gastroenterology 2017年第6期23卷 1018-1029页

作者： Sanne van Erp Ece Ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch mark van buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong Department of Gastroenterology and Hepatology Leiden University Medical Center C.J.Gorter Center Leiden University Medical Center Department of Radiology Leiden University Medical Center Department of Medical Statistics Leiden University Medical Center Center for Inflammatory Bowel Diseases University of California Los Angeles Department of Gastroenterology and Hepatology University Medical Center Utrecht Department of Psychiatry Leiden University Medical Center Department of Rheumatology Leiden University Medical Center Department of Neuropsychology Leiden University Medical Center Department of Radiology Leiden University Medical CenterLeiden

AIM To evaluate brain involvement in quiescent Crohn's disease (CD) patients with fatigue using quantitative magnetic resonance imaging(MRI).METHODS Multiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue(defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study *** Reduced glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine(P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow(P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P < 0.001). Cognitive functioning scores related to memory (P = 0.007) and executive functioning (P = 0.02) were lower in CD patients and both scores showed correlation with depression and anxiety. No correlation was found subcortical volumes between CD patients and controls in the T1-weighted analysis. In addition, no correlation was found between mental status and MRI *** This work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.

关键词：磁性的回声成像全身的发炎疲劳 Crohns 疾病认知

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Causes of Cretaceous subduction termination below South China and Borneo:Was the Proto-South China Sea underlain by an oceanic plateau?

引用

Geoscience Frontiers 2024年第2期15卷 100-124页

作者： Suzanna H.A.van de Lagemaat Licheng Cao Junaidi Asis Eldert L.Advokaat Paul R.D.Mason mark J.Dekkers Douwe J.J.van Hinsbergen Department of Earth Sciences Utrecht UniversityUtrechtthe Netherlands College of Marine Science and Technology China University of GeosciencesWuhanChina Faculty of Science and Natural Resources Universiti Malaysia SabahKota KinabaluMalaysia

The South China,Indochina,and Borneo margins surrounding the South China Sea contain long-lived arcs that became inactive at approximately 85 Ma,even though an embayment of oceanic crust(the‘Proto-South China Sea’)remained in the intervening *** oceanic crust eventually subducted in the Cenozoic below Borneo and the Cagayan arc,while the modern South China Sea opened in its *** investigate the enigmatic cessation of Mesozoic subduction below South China and Borneo,we studied a fragment of oceanic crust and overlying trench-fill sediments that accreted to NW Borneo during the final stages of Paleo-Pacific *** on radiolarian biostratigraphy of cherts overlying the pillow basalts and detrital zircon geochronology of the trench-fill,we constrained the minimum age of the oceanic crust during accretion to 40 *** shows that subduction cessation was not related to ridge *** analysis of pillow basalts revealed an enriched mid-ocean ridge basalt signature comparable to oceanic *** paleomagnetism,we show that this fragment of oceanic crust was not part of the Izanagi Plate but was part of a plate(the‘Pontus’Plate)separated from the Izanagi Plate by a subduction *** on the minimum 40 Ma age of the oceanic crust and its geochemistry,we suggest that Mesozoic subduction below South China and Borneo stopped when an oceanic plateau entered the trench,while the eastern plate margin with the Izanagi Plate remained *** show how our findings offer opportunities to restore plate configurations of the Panthalassa-Tethys junction region.

关键词： Proto-South China Sea Paleomagnetism Geochemistry Borneo Paleo-Pacific Izanagi Plate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Metabolic syndrome and the urinary microbiome of patients undergoing percutaneous nephrolithotomy

引用

Asian Journal of Urology 2024年第2期11卷 316-323页

作者： Ryan A.Dornbier Chirag P.Doshi Shalin C.Desai Petar Bajic Michelle van Kuiken mark Khemmani Ahmer V.Farooq Larissa Bresler Thomas M.T.Turk Alan J.Wolfe Kristin G.Baldea Loyola University Medical Center Department of UrologyMaywoodILUSA Loyola University Chicago Department of Microbiology and ImmunologyMaywoodILUSA

Objective:To identify possible stone-promoting microbes,we compared the profiles of microbes grown from stones of patients with and without metabolic syndrome(MetS).The association between MetS and urinary stone disease is well established,but the exact pathophysiologic relationship remains *** evidence suggests urinary tract dysbiosis may lead to increased nephrolithiasis ***:At the time of percutaneous nephrolithotomy,bladder urine and stone fragments were collected from patients with and without *** sample types were subjected to expanded quantitative urine culture(EQUC)and 16 S ribosomal RNA gene ***:Fifty-seven patients included 12 controls(21.1%)and 45 MetS patients(78.9%).Both cohorts were similar with respect to demographics and non-MetS *** controls had uric acid stone *** EQUC,bacteria were detected more frequently in MetS stones(42.2%)compared to controls(8.3%)(p=0.041).Bacteria also were more abundant in stones of MetS patients compared to *** validate our EQUC results,we performed 16 S ribosomal RNA gene *** 12/16(75.0%)sequence-positive stones,EQUC reliably isolated at least one species of the sequenced *** were detected in both“infectious”and“non-infectious”stone ***:Bacteria are more common and more abundant in MetS stones than control *** findings support a role for bacteria in urinary stone disease for patients with MetS regardless of stone composition.

关键词： Nephrolithiasis Urolithiasis Metabolic syndrome Urinary microbiome Percutaneous nephrolithotomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Exercise training improves long-term memory in obese mice

引用

Life Metabolism 2024年第1期3卷 37-50页

作者： Oliver K.Fuller Casey L.Egan Tina L.Robinson Nimna Perera Heidy K.Latchman Lauren V.Terry Emma D.McLennan Carolina Chavez Emma L.Burrows John W.Scott Robyn M.Murphy Henriette van Praag Martin Whitham mark A.Febbraio Monash Institute of Pharmaceutical Sciences Monash UniversityMelbourneVictoria3052Australia La Trobe Institute for Molecular Science La Trobe UniversityMelbourneVictoria3086Australia Florey Institute of Neuroscience and Mental Health University of MelbourneMelbourneVictoria3052Australia Department of Biomedical Sciences Charles E.Schmidt College of Medicineand Stiles-Nicholson Brain InstituteFlorida Atlantic UniversityJupiterFL 33458United States College of Life and Environmental Sciences University of BirminghamEdgbastonBirmingham B152TTUnited Kingdom

Obesity has been linked to a range of pathologies,including *** contrast,regular physical activity is associated with the prevention or reduced progression of ***,physical activity can improve memory and spatial cognition,reduce age-related cognitive decline,and preserve brain volume,but the mechanisms are not fully ***,we investigated whether any detrimental effects of high-fat diet(HFD)-induced obesity on cognition,motor behavior,adult hippocampal neurogenesis,and brain-derived neurotrophic factor(BDNF)could be mitigated by voluntary exercise training in male C57Bl/6 ***-induced impairment of motor function was not reversed by ***,voluntary wheel running improved long-term memory and increased hippocampal neurogenesis,suggesting that regular physical activity may prevent cognitive decline in obesity.

关键词： obesity exercise cognition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modulating p-type doping of two-dimensional material palladium diselenide

引用

Nano Research 2024年第4期17卷 3232-3244页

作者： Jiali Yang Yu Liu En-Yang Wang Jinbo Pang Shirong Huang Thomas Gemming Jinshun Bi Alicja Bachmatiuk Hao Jia Shu-Xian Hu Chongyun Jiang Hong Liu Gianaurelio Cuniberti Weijia Zhou mark H Rümmeli Institute for Advanced Interdisciplinary Research(iAIR) University of JinanJinan 250022China Institute for Materials Chemistry Leibniz Institute for Solid State and Materials Research Dresden(IFW Dresden)20 Helmholtz StrasseDresden 01069Germany State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China College of Energy Soochow Institute for Energy and Materials Innovations Soochow UniversitySuzhou 215006China Key Laboratory of Advanced Carbon Materials and Wearable Energy Technologies of Jiangsu Province Soochow UniversitySuzhou 215006China School of Integrated Circuits University of Chinese Academy of SciencesBeijing 101408China Institute of Microelectronics of Tianjin Binhai New Area Tianjin 300451China Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Lukasiewicz Research Network PORT Polish Center for Technology DevelopmentStablowicka 147Wroclaw 54-066Poland School of Mathematics and Physics University of Science and Technology BeijingBeijing 100083China College of electronic information and optical engineering Nankai UniversityTianjin 300350China Centre of Polymer and Carbon Materials Polish Academy of SciencesM.Curie Sklodowskiej 34Zabrze 41-819Poland Center for Energy and Environmental Technologies VŠB-Technical University of Ostrava17.Listopadu 15Ostrava 70833Czech Republic State Key Laboratory of Crystal Materials Center of Bio&Micro/Nano Functional MaterialsShandong UniversityJinan 250100China Dresden Center for Computational Materials Science Technische Universität DresdenDresden 01062Germany Dresden Center for Intelligent Materials(GCL DCIM) Technische Universität DresdenDresden 01062Germany Institute for Materials Science and Max Bergmann Center of Biomaterials Technische Universität DresdenDresden 01069Germany Center for Advancing Electronics Dresden Technische Universität DresdenDresden 01069Germany

The van der Waals heterostructures have evolved as novel materials for complementing the Si-based semiconductor ***-10 noble metal dichalcogenides(e.g.,PtS_(2),PtSe_(2),PdS_(2),and PdSe_(2))have been listed into two-dimensional(2D)materials toolkit to assemble van der Waals *** them,PdSe_(2) demonstrates advantages of high stability in air,high mobility,and wide tunable ***,the regulation of p-type doping of PdSe_(2) remains unsolved problem prior to fabricating p–n junction as a fundamental platform of semiconductor ***,a quantitative method for the controllable doping of PdSe_(2) is yet to be *** this study,the doping level of PdSe_(2) was correlated with the concentration of Lewis acids,for example,SnCl_(4),used for *** the transfer characteristics,the threshold voltage(the gate voltage corresponding to the minimum drain current)increased after SnCl_(4) soaking ***_(2) transistors were soaked in SnCl_(4) solutions with five different *** threshold voltages from the as-obtained transfer curves were extracted for linear fitting to the threshold voltage versus doping concentration correlation *** study provides in-depth insights into the controllable p-type doping of PdSe_(2).It may also push forward the research of the regulation of conductivity behaviors of 2D materials.

关键词： two-dimensional(2D)materials Lewis acid treatment p-type doping field-effect transistors transfer characteristic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Direct evidence of microbiological water quality changes on bacterial quantity and community caused by plumbing system

引用

Journal of Environmental Sciences 2022年第6期34卷 175-183页

作者： Jun Li Anran Ren Ed van der mark Gang Liu Key Laboratory of Drinking Water Science and Technology Research Centre for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Dunea Water Company Plaza of the United Nations 11-15Zoetermeer 2700 ATthe Netherlands Sanitary engineering Department of Water managementFaculty of Civil Engineering and GeosciencesDelft University of TechnologyDelft 2600 GAthe Netherlands

Drinking water quality deteriorates from treatment plant to customer taps, especially in the plumbing system. There is no direct evidence about what the differences are contributed by plumbing system. This study compared the water quality in the water main and at customer tap by preparing a sampling tap on the water main. The biomass was quantified by adenosine triphosphate(ATP) and the microbial community was profiled by 454 *** results showed that in distribution pipes, biofilm contributed >94% of the total biomass,while loose deposits showed little contribution(< 2%) because of the low amount of loose deposits. The distribution of biological stable water had minor effects on the microbiocidal water quality regarding both quantity(ATP 1 ng/L vs. 1.7 ng/L) and community of the bacteria. Whereas the plumbing system has significant contribution to the increase of active biomass(1.7 ng/L vs. 2.9 ng/L) and the changes of bacterial community. The relative abundance of Sphingomonas spp. at tap(22%) was higher than that at water main(2%), while the relative abundance of Pseudomonas spp. in tap water(15%) was lower than that in the water from street water main(29%). Though only one location was prepared and studied, the present study showed that the protocol of making sampling tap on water main offered directly evidences about the impacts of plumbing system on tap water quality, which makes it possible to distinguish and study the processes in distribution system and plumbing system separately.

关键词： Drinking water distribution system Plumbing system Microbiological water quality Sampling program 454 pyrosequencing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Global change and biological invasions

引用

Journal of Plant Ecology 2022年第3期15卷 425-428页

作者： Yu-Long Feng Daolin Du mark van Kleunen Liaoning Key Laboratory for Biological Invasions and Global Changes College of Bioscience and BiotechnologyShenyang Agricultural UniversityShenyang 110866China School of the Environment and Safety Engineering Jiangsu UniversityZhenjiang 212013China Department of Biology University of KonstanzKonstanzGermany Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation Taizhou UniversityTaizhou 318000China

Invasion by exotic species is one of the serious socio-economic,environmental and ecological problems currently faced by *** invasions have changed the species composition,structure and function of ecosystems,and are seriously threatening global biodiversity,economy and human health(Iqbal et al.2021;Wang et al.2020;Yang et al.2021;Zhao et al.2020;Zheng et al.2015).Biological invasions have resulted in an economic loss of at least US$1.288 trillion over the past few decades worldwide(Diagne et al.2021).As a consequence of these far-reaching impacts,biological invasions have become a hot research topic in modern ecology,and attract major attention from international organizations,governments and scientists all over the world.

关键词： invasion consequence

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Supercurrent decay in ballistic magnetic Josephson junctions

引用

npj Computational Materials 2022年第1期8卷 186-196页

作者： HervéNess Ivan A.Sadovskyy Andrey E.Antipov mark van Schilfgaarde Roman M.Lutchyn Department of Physics King’s College LondonStrand CampusLondonWC2R 2LSUK Microsoft Quantum Microsoft Station QUniversity of CaliforniaSanta BarbaraCA93106USA National Renewable Energy Laboratory GoldenCO80401USA

We investigate transport properties of ballistic magnetic Josephson junctions and establish that suppression of supercurrent is an intrinsic property of the junctions,even in absence of *** studying the role of ferromagnet thickness,magnetization,and crystal orientation we show how the supercurrent decays exponentially with thickness and identify two mechanisms responsible for the effect:(i)large exchange splitting may gap out minority or majority carriers leading to the suppression of Andreev reflection in the junction,(ii)loss of synchronization between different modes due to the significant dispersion of the quasiparticle velocity with the transverse *** results for Nb/Ni/Nb junctions are in good agreement with recent experimental *** approach combines density functional theory and the Bogoliubov-de Gennes model and opens a path for material composition optimization in magnetic Josephson junctions and superconducting magnetic spin valves.

关键词： Josephson decay magnetic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diffusion tensor imaging in the courtroom:Distinction between scientific specificity and legally admissible evidence

引用

World Journal of Clinical Cases 2023年第19期11卷 4477-4497页

作者： Jennifer Christine van Velkinburgh mark D Herbst Stewart M Casper Science Communication Filipodia Publishing LLCSanta FeNM 87505United States Diagnostic Radiology Independent Diagnostic Radiology IncSt PetersburgFL 33711United States Personal Injury Law Casper&DeToledo LLCStamfordCT 06905United States

Interest and uptake of science and medicine peer-reviewed literature by readers outside of a paper’s topical subject,field or even discipline is *** the application of knowledge from one field or discipline to others can stimulate innovative solutions to problems facing modern society,it is also fraught with danger for *** the practice of law in the United States,academic papers are submitted to the courts as evidence in personal injury litigation from both the plaintiff(complainant)and *** transcendence of an academic publication over disciplinary boundaries is immediately met with the challenge of application by a group that inherently lacks in-depth knowledge on the scientific method,the practice of evidence-based medicine,or the publication process as a structured and internationally synthesized process involving peer review and guided by ethical standards and norms.A modern-day example of this is the ongoing conflict between the sensitivity of diffusion tensor imaging(DTI)and the legal standards for admissibility of evidence in litigation cases of mild traumatic brain injury(mTBI).In this review,we amalgamate the peer-reviewed research on DTI in mTBI with the court’s rationale underlying decisions to admit or exclude evidence of DTI abnormalities to support claims of brain *** found that the papers which are critical of the use of DTI in the courtroom reflect a primary misunderstanding about how diagnostic biomarkers differ legally from relevant and admissible *** clinical use of DTI to identify white matter abnormalities in the brain at the chronic stage is a valid methodology both clinically as well as forensically,contributes data that may or may not corroborate the existence of white matter damage,and should be admitted into evidence in personal injury trials if supported by a *** also delve into an aspect of science publication and peer review that can be manipulated by scientists and clinicians to

关键词： Diffuse axonal injury Mild brain injury Magnetic resonance imaging Neuroimaging Medicolegal Litigation Medical jurisprudence Ethics Peer review Publishing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Simultaneous screening and classification of diabetic retinopathy and age-related macular degeneration based on fundus photos——a prospective analysis of the RetCAD system

引用

International Journal of Ophthalmology(English edition) 2022年第12期15卷 1985-1993页

作者： Christos Skevas Hanah Weindler Max Levering Jonne Engelberts mark van Grinsven Toam Katz University Clinic Eppendorf Hamburg Hamburg 20246Germany Thirona B.V. Toernooiveld 3006525 ECNijmegenThe Netherlands

AIM:To assess the accuracy of an artificial intelligence(AI)based software(Ret CAD,Thirona,The Netherlands)to identify and grade age-related macular degeneration(AMD)and diabetic retinopathy(DR)simultaneously based on fundus ***:This prospective study included 1245 eyes of 630 patients attending an ophthalmology day-care *** photos were acquired and parallel graded by the Ret CAD AI software and by an expert reference examiner for image quality,and staging of AMD and *** was provided by a second expert examiner in case of disagreement between the AI software and the reference *** analysis was performed on eye-level and on patient-level,by summarizing the individual image level-gradings into and eye-level or patient-level score,*** performance of the Ret CAD system was measured using receiver operating characteristics(ROC)analysis and sensitivity and specificity for both AMD and DR were ***:The Ret CAD achieved an area under the ROC(Az)of 0.926 with a sensitivity of 84.6%at a specificity of 84.0%for image *** image level,the Ret CAD software achieved Az values of 0.964 and 0.961 with sensitivity/specificity pairs of 98.2%/79.1%and 83.9%/93.3%for AMD and DR,*** patient level,the Ret CAD software achieved Az values of 0.960 and 0.948 with sensitivity/specificity pairs of 97.3%/73.3%and 80.0%/90.1%for AMD and DR,*** adjudication by the second expert examiner sensitivity/specificity increases on patient-level to 98.6%/78.3%and 100.0%/92.3%for AMD and DR,***:The Ret CAD offers very good sensitivity and specificity compared to manual grading by experts and is in line with that obtained by similar automated grading *** Ret CAD AI software enables simultaneous grading of both AMD and DR based on the same fundus *** sensitivity may be adjusted according to the desired acceptable sensitivity and *** simplicity cloud base i

关键词： RetCAD age-related macular degeneration diabetic retinopathy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：