检索结果-南通市图书馆

Phylogenetic placement of bizarre karschiellid earwigs

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insect Science 2024年第3期31卷 989-992页

作者： Petr Kocárek Ivona Horká Vojtěch Bonczek markéta Kirstová Department of Biology and Ecology University of OstravaOstravaCzech Republic

Dear Editor,Karschiellidae are a mysterious group of earwigs that attract attention not only because of their interesting appearance and unexplained way of life but also mainly due to their unclear *** phylogenetic relationships of karschiellids remain speculative even 120 years since the family was described,above all due to the unavailability of DNA-grade material for molecular phylogenetic *** study includes successfully sequenced representatives of the Karschiellidae for the first time,and a probable evolutionary scheme and natural classification of karschiellids are proposed based on the constructed multigene phylogeny.

关键词： classification. phylogeny evolutionary

Management of monogenic diabetes in pregnancy:A narrative review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第1期15卷 15-23页

作者： Mohammad Sadiq Jeeyavudeen Sarah R Murray mark W J Strachan Metabolic Unit Western General HospitalEdinburgh EH42XUUnited Kingdom MRC Centre for Reproductive Health University of Edinburgh Queen’s Medical Research InstituteEdinburgh EH164TJUnited Kingdom

Pregnancy in women with monogenic diabetes is potentially complex,with significant implications for both maternal and fetal *** these,maturity-onset diabetes of the young(MODY)stands out as a prevalent monogenic diabetes subtype frequently encountered in clinical *** subtype of MODY requires a distinct approach tailored to the pregnancy,diverging from management strategies in non-pregnant *** MODY(GCK-MODY)typically does not require treatment outside of pregnancy,but special considerations arise when a woman with GCK-MODY becomes *** glycemic targets in GCK-MODY pregnancies are not exclusively dictated by the maternal/paternal MODY genotype but are also influenced by the genotype of the developing *** pregnancy,the choice between sulfonylurea or insulin for treating hepatocyte nuclear factor 1-alpha(HNF1A)-MODY and HNF4A-MODY depends on the mother’s specific circumstances and the available *** of other rarer MODY subtypes is individu-alized,with decisions made on a case-by-case ***,a collaborative approach involving expert diabetes and obstetric teams is crucial for the compre-hensive management of MODY pregnancies.

关键词： Diabetes Pregnancy Maturity-onset diabetes of the young Insulin Sulphonylurea Glucokinase Hepatocyte nuclear factor 1-alpha,hepatocyte nuclear factor 1-beta,and hepatocyte nuclear factor 4-alpha

Massive inferior wall aneurysm presenting with ventricular tachycardia and refractory cardiomyopathy requiring multiple interventions:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2024年第6期16卷 363-369页

作者： Anderson Anuforo Jake Charlamb Dan Draytsel mark Charlamb Department of Medicine SUNY Upstate Medical UniversitySyracuseNY 13210United States College of Medicine Norton College of MedicineSUNY Upstate Medical UniversitySyracuseNY 13210United States Division of Cardiology SUNY Upstate Medical UniversitySyracuseNY 13210United States

BACKGROUND Inferior wall left ventricular aneurysms are rare,they develop after transmural myocardial infarction(MI)and may be associated with poorer *** present a unique case of a large aneurysm of the inferior wall complicated by ventricular tachycardia(VT)and requiring surgical resection and mitral valve *** SUMMARY A 59-year-old male was admitted for VT one month after he had a delayed presentation for an inferior ST-segment elevation MI and was discovered to have a large true inferior wall aneurysm on echocardiography and confirmed on coronary computed tomography(CT)*** to the sustained VT,concern for aneurysm expansion,and persistent heart failure symptoms,the patient was referred for surgical resection of the aneurysm with patch repair,mitral valve replacement,and automated implantable cardioverter defibrillator insertion with significant improvement in functional and clinical *** Inferior wall aneurysms are rare and require close monitoring to identify electrical or contractile *** CT angiography can outline anatomic details and guide surgical intervention to ameliorate life-threatening complications and improve performance status.

关键词： Inferior wall aneurysm True aneurysm Ventricular tachycardia Electrophysiology Structural interventional cardiology Case report

Relative carcinogenicity of tacrolimus vs mycophenolate after solid organ transplantation and its implications for liver transplant care

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第4期16卷 650-660页

作者： Dorothy Liu mark M Youssef Josephine A Grace Marie Sinclair Department of Gastroenterology Austin HealthMelbourne 3084VictoriaAustralia Victorian Liver Transplant Unit Austin HealthMelbourne 3084VictoriaAustralia Department of Medicine University of MelbourneMelbourne 3084VictoriaAustralia

BACKGROUND De novo malignancy is a leading cause of late morbidity and mortality in liver transplant *** immunosuppression has been shown to contribute to post-transplant malignancy(PTM)*** is emerging evidence on the differential carcinogenic risk profile of individual immunosuppressive drugs,independent of the net effect of *** inhibitors such as tacrolimus may promote tumourigenesis,whereas mycophenolic acid(MPA),the active metabolite of mycophenolate mofetil,may limit tumour *** transplantation(LT)is relatively unique among solid organ transplantation in that immunosuppression monotherapy with either tacrolimus or MPA is often achievable,which makes careful consideration of the risk-benefit profile of these immunosuppression agents particularly relevant for this ***,there is limited clinical data on this subject in both LT and other solid organ transplant *** To investigate the relative carcinogenicity of tacrolimus and MPA in solid organ *** A literature search was conducted using MEDLINE and Embase databases using the key terms“solid organ transplantation”,“tacrolimus”,“mycophenolic acid”,and“carcinogenicity”,in order to identify relevant articles published in English between 1st January 2002 to 11th August *** terms,synonyms and explosion of MeSH terms,Boolean operators and truncations were also utilised in the *** lists of retrieved articles were also reviewed to identify any additional *** duplicates,abstracts from 1230 records were screened by a single reviewer,whereby 31 records were reviewed in ***-text articles were assessed for eligibility based on pre-specified inclusion and exclusion *** A total of 6 studies were included in this *** studies were large population registries or cohort studies,which varied in transplant era,type of organ transplanted and immunosuppression protocol us

关键词： Immunosuppression Solid organ transplantation Liver transplantation Carcinogenicity Tacrolimus Mycophenolate

On Two Types of Stability of Solutions to a Pair of Damped Coupled Nonlinear Evolution Equations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Pure Mathematics 2024年第5期14卷 354-366页

作者： mark Jones School of Computer Science and Mathematics Kingston University London UK

The stability of a set of spatially constant plane wave solutions to a pair of damped coupled nonlinear Schrödinger evolution equations is considered. The equations could model physical phenomena arising in fluid dynamics, fibre optics or electron plasmas. The main result is that any small perturbation to the solution remains small for all time. Here small is interpreted as being both in the supremum sense and the square integrable sense.

关键词： Nonlinear Schrödinger Equation Stability Capillary-Gravity Waves

Antimicrobial stewardship and targeted therapies in the changing landscape of maternal sepsis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Intensive Medicine 2024年第1期4卷 46-61页

作者： Nishel M Shah Esmita Charani Damien Ming Fook-Choe Cheah mark R Johnson Department of Metabolism Digestion and ReproductionImperial College LondonChelsea and Westminster HospitalLondonUK Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance Imperial College LondonLondonUK Division of Infectious Diseases and HIV Medicine Department of MedicineGroote Schuur HospitalUniversity of Cape TownCape TownSouth Africa Department of Infectious Diseases Imperial College LondonChelsea and Westminster HospitalLondonUK Department of Paediatrics Faculty of MedicineUniversiti Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia

Pregnant and postnatal women are a high-risk population particularly prone to rapid progression to sepsis with significant morbidity and mortality ***,severe maternal infections can have a serious detrimental impact on neonates with almost 1 million neonatal deaths annually attributed to maternal infection or *** this review we discuss the susceptibility of pregnant women and their specific physiological and immunological adaptations that contribute to their vulnerability to sepsis,the implications for the neonate,as well as the issues with antimicrobial stewardship and the challenges this poses when attempting to reach a balance between clinical care and urgent ***,we review advancements in the development of pregnancy-specific diagnostic and therapeutic approaches and how these can be used to optimize the care of pregnant women and neonates.

关键词： Sepsis Pregnancy Immunology Cardiovascular Personalised medicine Antibiotic stewardship

SARS-CoV-2 and innate immunity:the good,the bad,and the"goldilocks"

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2024年第2期21卷 171-183页

作者： Benjamin L.Sievers mark T.K.Cheng Kata Csiba Bo Meng Ravindra K.Gupta Department of Medicine University of CambridgeCambridgeUK Cambridge Institute of Therapeutic Immunology&Infectious Disease(CITID) Department of MedicineUniversity of CambridgeCambridgeUk

An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of *** about this interplay can not only help us identify biological mechanisms but also reveal pathogen vulnerabilities that can be leveraged *** humoral response to SARS-CoV-2 infection has been the focus of intense research,and the role of the innate immune system has received significantly less ***,we review current knowledge of the innate immune response to SARS-CoV-2 infection and the various means SARS-CoV-2 employs to evade innate defense *** also consider the role of innate immunity in SARS-CoV-2 vaccines and in the phenomenon of long COVID.

关键词： SARS-CoV-2 Innate immune response Interferon Cytokines Inflammation Antiviral targets

Females adopt sexual catalepsy to facilitate mating

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2024年第2期70卷 174-181页

作者： Jihe Liu Keke Liu Yu Tang Weihua Wang Xiang Xu Jianhui Liang Yonghong Xiao mark A.Elgar College of Life Sciences Jinggangshan UniversityJi'anJiangxi 343009China Pharmaceutical Center Tsinghua UniversityBeijing 100084China College of Life Sciences Hunan Normal UniversityChangshaHunan 410081China School of Pharmaceutical Sciences Peking UniversityBeijing 100083China School of BioSciences University of MelbourneMelbourneVictoria 3010Australia School of Life Sciences and Technology Tongii UniversityShanghai 200092China

Theory predicts that males and females of dioecious species typically engage in an evolutionary sexual conflict over the frequency and choice of mating *** sexual cannibalism,a particularly dramatic illustration of this conflict,is widespread in certain animal taxa including ***,females of some funnel weaving spiders that are generally aggressive to conspecifics enter a cataleptic state after male courtship,ensuring the males can mate without risk of *** this study,we demonstrated that the physical posture and duration,metabo-lites,and central neurotransmitters of females of Aterigena aculeata in sexual catalepsy closely resemble females in thanatosis but are distinct from those in anesthesia,indicating that the courted females feign death to eliminate the risk of potentially aggressive responses and thereby allow preferred males to *** the taxonomically widespread thanatosis,which generally represents a deceptive visual signal that acts against the interest of the receivers,sexual catalepsy of females in the funnel weaving spiders may deliver a sexual-receptive signal to the courting males and thereby benefit both the signal senders and ***,sexual catalepsy in *** may not reflect a conflict butrather a confluence of interest betweenthe sexes.

关键词： female catalepsy funnel weaving spiders mate choice mating strategy sexual behavior.

The Adventures Of Tom Sawyer Sawyer（十四）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

语数外学习(高中版上旬) 2024年第6期 85-90页

作者： mark Twain

CHAPTERⅫOne of the reasons why Tom’s mind had drifted away from its secret troubles was,that it had found a new and weighty matter to interest itself *** Thatcher had stopped coming to *** had struggled with his pride a few days,and tried to“whistle her down the wind”,but *** began to find himself hanging around her father’s house,nights,and feeling very *** was *** if she should die!There was distraction in the *** no longer took an interest in war,nor even in *** charm of life was gone;there was nothing but dreariness *** put

关键词：