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Nevanlinna theory of meromorphic functions on annuli

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Science China Mathematics 2010年第3期53卷 547-554页

作者： LUND mark Department of Mathematics College of DuPage

In this survey paper, we discuss the recent development of Nevanlinna theory of meromorphic functions on annuli, which extends results in Nevanlinna theory in the complex plane or in a disk. In particular, we show that the approach taken on annuli is a unified treatment of functions meromorphic in the complex plane, a disk and an annulus. It allows one to obtain many results in the complex plane and in a disk as corollaries of our results in annuli.

关键词： Nevanlinna theory meromorphic function annulus

Biosphere 2’s Lessons about Living on Earth and in Space

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Space(Science & Technology) 2021年第1期2021卷 274-284页

作者： mark Nelson Institute of Ecotechnics(US/UK) USA

Biosphere 2,the largest and most biodiverse closed ecological system facility yet created,has contributed vital lessons for living with our planetary biosphere and for long-term habitation in *** the space life support perspective,Biosphere 2 contrasted with previous BLSS work by including areas based on Earth wilderness biomes in addition to its provision for human life support and by using a soil-based intensive agricultural system producing a complete human *** previous BLSS system had included domestic farm *** human and domestic animal wastes were also recycled and returned to the crop *** 2 was important as a first step towards learning how to miniaturize natural ecosystems and develop technological support systems compatible with *** 2’s mostly successful operation for three years(1991-1994)changed thinking among space life support scientists and the public at large about the need for minibiospheres for long-term habitation in *** an Earth systems laboratory,Biosphere 2 was one of the first attempts to make ecology an experimental science at a scale relevant to planetary issues such as climate change,regenerative agriculture,nutrient and water recycling,loss of biodiversity,and understanding of the roles wilderness biomes play in the Earth’s *** 2 aroused controversy because of narrow definitions and expectations of how science is to be *** cooperation between engineers and ecologists and the requirement to design a technosphere that supported the life inside without harming it have enormous relevance to what is required in our global *** of bioregenerative life support systems for near-term space applications such as initial Moon and/or Mars bases,will be severely limited by high costs of transport to space and so will rely on lighter weight,hydroponic systems of growing plants which will focus first on water and air regeneration and gradually increase its production of fo

关键词： Earth Biosphere bases

Structure-function studies of the influenza virus RNA polymerase PA subunit

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Science China(Life Sciences) 2009年第5期52卷 450-458页

作者： mark BARTLAM College of Life Sciences and Tianjin State Laboratory of Protein Science Nankai University

The influenza virus RNA-dependent RNA polymerase is a heterotrimeric complex (PA, PB1 and PB2) with multiple enzymatic activities for catalyzing viral RNA transcription and replication. The roles of PB1 and PB2 have been clearly defined, but PA is less well understood. The critical role of the polymerase complex in the influenza virus life cycle and high sequence conservation suggest it should be a major target for therapeutic intervention. However, until very recently, functional studies and drug discovery targeting the influenza polymerase have been hampered by the lack of three-dimensional structural information. We will review the recent progress in the structure and function of the PA subunit of influenza polymerase, and discuss prospects for the development of anti-influenza therapeutics based on available structures.

关键词： influenza polymerase PA subunit crystal structure endonuclease protein-protein interaction

Liver immunology and its role in inflammation and homeostasis

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Cellular & Molecular Immunology 2016年第3期13卷 267-276页

作者： mark W Robinson Cathal Harmon Cliona o'Farrelly School of Biochemistry and Immunology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin D2 Ireland School of Medicine TrinityBiomedical Sciences Institute Trinity College Dublin Dublin D2 Ireland

The human liver is usually perceived as a non-immunological organ engaged primarily in metabolic, nutrient storage and detoxification activities. However, we now know that the healthy liver is also a site of complex immunological activity mediated by a diverse immune cell repertoire as well as non-hematopoietic cell populations. In the nondiseased liver, metabolic and tissue remodeling functions require elements of inflammation. This inflammation, in combination with regular exposure to dietary and microbial products, creates the potential for excessive immune activation. In this complex microenvironment, the hepatic immune system tolerates harmless molecules while at the same time remaining alert to possible infectious agents, malignant cells or tissue damage. Upon appropriate immune activation to challenge by pathogens or tissue damage, mechanisms to resolve inflammation are essential to maintain liver homeostasis. Failure to clear ＇dangerous＇ stimuli or regulate appropriately activated immune mechanisms leads to pathological inflammation and disrupted tissue homeostasis characterized by the progressive development of fibrosis, cirrhosis and eventual liver failure. Hepatic inflammatory mechanisms therefore have a spectrum of roles in the healthy adult liver; they are essential to maintain tissue and organ homeostasis and, when dysregulated, are key drivers of the liver pathology associated with chronic infection, autoimmunity and malignancy. In this review, we explore the changing perception of inflammation and inflammatory mediators in normal liver homeostasis and propose targeting of liver-specific immune regulation pathways as a therapeutic approach to treat liver disease.

关键词： homeostasis immunology inflammation liver tolerance

Microstructural Evolution of Nb–V–Mo and V Containing TRIP-assisted Steels during Thermomechanical Processing

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Journal of Materials Science & Technology 2017年第4期33卷 311-320页

作者： Erfan Abbasi William mark Rainforth Department of Materials Science and Engineering The University of Sheffield

The microstructural evolution and precipitation behaviour of Nb–V–Mo and single V containing transformation induced plasticity assisted steels were investigated during thermomechanical processing. A plane strain compression testing machine was used to simulate the thermomechanical processing. Microstructures were characterised by optical microscopy, scanning-transmission electron microscopy and microanalysis, and X-ray diffraction analysis, and Vickers hardness was obtained from the deformed specimens. The resulting microstructure of both Nb–V–Mo and V steels at room temperature primarily consisted of an acicular/bainitic ferrite, retained austenite and martensite surrounded by allotriomorphic *** TEM analysis showed that a significant number of Nb（V,Mo）（C,N） precipitates were formed in the microstructure down to the finishing stage in Nb–V–Mo steel（i.e. 830℃）. It was also found that the V（C,N）precipitation primarily occurred in both ferrite and deformed austenite below the finishing stage. The results suggested that Nb–Mo additions considerably increased the temperature stability of microalloy precipitates and controlled the microstructural evolution of austenite. However, the microalloy precipitation did not cause a significant precipitation strengthening in both Nb–V–Mo and V steels at room temperature.

关键词： Microalloyed TRiP-assisted steel Thermomechanical processing Precipitation behaviour Microstructural evolution

Continuous Metadata in Continuous Integration,Stream Processing and Enterprise Dataops

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Data Intelligence 2023年第1期5卷 275-287页

作者： mark Underwood Data Kitchen Headquarters One Broadway14th Floor CambridgeMA 02142USA

Implementations of metadata tend to favor centralized,static *** depiction is at variance with the past decade of focus on big data,cloud native architectures and streaming *** data velocity can demand a correspondingly dynamic view of *** trends,which include Devops,CI/CD,Dataops and data fabric,are *** specific cloud native tools are reviewed and weaknesses in their current metadata use are *** are suggested which better exploit capabilities of streaming platform paradigms,in which metadata is continuously collected in dynamic *** cloud native software features are identified which could enable streamed metadata to power real time data fusion or fine tune automated reasoning through real time ontology updates.

关键词： Metadata real time data stream processing

Effect of rubrene:P3HT bilayer on photovoltaic performance of perovskite solar cells with electrodeposited Zno nanorods

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Journal of Energy Chemistry 2018年第2期27卷 455-462页

作者： Christian mark Pelicano Hisao Yanagi Graduate School of Materials Science Nara Institute of Science and Technology

Improved photovoltaic performance of perovskite solar cells is demonstrated through the synergistic effect of electrodeposited Zno nanorods and rubrene：P3HT bilayer as electron and hole-transporting layers,respectively. Highly crystalline Zno nanorods were obtained by electrochemical deposition in a chloride medium. Additionally, rubrene interlayer was able to passivate or cover the grain boundaries of perovskite film effectively that led to reduced leakage current. A perovskite solar cell optimized with Zno nanorods and rubrene：P3HT bilayer achieved a maximum efficiency of 4.9% showing reduced hysteresis behavior compared with the device having P3HT as the only hole-transporting layer. The application of longer nanorods led to better perovskite infiltration and shorter charge carrier path length. These results highlight the potential of electrodeposited Zno nanorods and rubrene：P3HT bilayer as charge selective layers for efficient perovskite solar cells.

关键词： Rubrene:P3HT bilayer Electrodeposited Zno nanorods Perovskite solar cells

The current perspective of the PA 1957 gas well pillar study and its implications for longwall gas well pillars

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International Journal of Mining Science and Technology 2021年第1期31卷 117-126页

作者： Peter Zhang Daniel Su Chris mark CDC NIoSH Pittsburgh Mining Research DivisionPittsburghPA 15236USA Mine Safety and Health Administration PittsburghPA 15217USA

Many states rely upon the Pennsylvania 1957 Gas Well Pillar Study to evaluate the coal barrier surrounding gas *** study included 77 gas well failure cases that occurred in the Pittsburgh and Freeport coal seams over a 25-year *** the time,coal was mined using the room-and-pillar mining method with full or partial pillar recovery,and square or rectangle pillars surrounding the gas wells were left to protect the *** study provided guidelines for pillar sizes under different overburden depths up to 213 m(700 ft).The 1957 study has also been used to determine gas well pillar sizes in longwall mines since longwall mining began in the 1970 *** original study was developed for room-and-pillar mining and could be applied to gas wells in longwall chain pillars under shallow ***,under deep cover,severe deformations in gas wells have occurred in longwall chain ***,with a better understanding of coal pillar mechanics,new insight into subsidence movements induced by retreat mining,and advances in numerical modeling,it has become both critically important and feasible to evaluate the adequacy of the 1957 study for longwall gas well *** this paper,the data from the 1957 study is analyzed from a new perspective by considering various factors,including overburden depth,failure location,failure time,pillar safety factor(SF),and floor *** pillar SF and floor pressure are calculated by considering abutment pressure induced by full pillar recovery.A statistical analysis is performed to find correlations between various factors and helps identify the most significant factors for the stability of gas wells influenced by retreat *** analyzing the data from the 1957 study,the guidelines for gas well pillars in the 1957 study are evaluated for their adequacy for roomand-pillar mining and their applicability to longwall *** modeling is used to model the stability of gas wells by quantifying the mining-induced s

关键词： Gas well pillar Pennsylvania 1957 gas well pillar study Room-and-pillar mining Longwall mining

Hybrid ecophysiological growth model for deciduous Populus tomentosa plantation in northern China

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Forest Ecosystems 2025年第1期 112-120页

作者： Serajis Salekin mark Bloomberg Benye Xi Jinqiang Liu Yang Liu Doudou Li Euan G.Mason Scion Research (New Zealand Forest Research Institute Ltd.) New Zealand School of Forestry University of Canterbury State Key Laboratory of Efficient Production of Forest Resources Beijing Forestry University Key Laboratory for Silviculture and Forest Ecosystem Research in Arid-and Semi-Arid Region of National Forestry and Grassland Administration Beijing Forestry University Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry University Institute of Medicinal Plant Development Chinese Academy of Medical Sciences Peking Union Medical College

Short rotation plantation forestry（SRF） is being widely adopted to increase wood production, in order to meet global demand for wood products. However, to ensure maximum gains from SRF, optimised management regimes need to be established by integrating robust predictions and an understanding of mechanisms underlying tree growth. Hybrid ecophysiological models, such as potentially useable light sum equation（PULSE） models, are useful tools requiring minimal input data that meet the requirements of SRF. PULSE models have been tested and calibrated for different evergreen conifers and broadleaves at both juvenile and mature stages of tree growth with coarse soil and climate data. Therefore, it is prudent to question: can adding detailed soil and climatic data reduce errors in this type of model? In addition, PULSE techniques have not been used to model deciduous species, which are a challenge for ecophysiological models due to their phenology. This study developed a PULSE model for a clonal Populus tomentosa plantation in northern China using detailed edaphic and climatic data. The results showed high precision and low bias in height（m） and basal area(m2·ha-1) predictions. While detailed edaphoclimatic data produce highly precise predictions and a good mechanistic understanding, the study suggested that local climatic data could also be employed. The study showed that PULSE modelling in combination with coarse level of edaphic and local climate data resulted in reasonably precise tree growth prediction and minimal bias.

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