检索结果-南通市图书馆

Na.opa.ticle Ta.geting with a.tibodies in the Centra. Nervous System

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedica. Engineering Frontiers 2023年第1期4卷 159-176页

作者： Ju Hyun Lee Da.a.V.chapman W.mark Sa.tzma. Depa.tment of Biomedica. Engineering Yale UniversityNew HavenCTUSA

Trea.ments for disea.e in the centra. nervous system(CNS)a.e limited beca.se of difficulties in a.ent penetra.ion through the blood-bra.n ba.rier,a.hieving optima. dosing,a.d mitiga.ing off-ta.get *** prospect of precision medicine in CNS trea.ment suggests a. opportunity for thera.eutic na.otechnology,which offers tuna.ility a.d a.a.ta.ility to a.dress specific disea.es a. well a. ta.geta.ility when combined with a.tibodies(a.s).Here,we review the stra.egies to a.ta.h a.s to na.opa.ticles(NPs),including conventiona. a.proa.hes of chemisorption a.d physisorption a. well a. a.tempts to combine irreversible a. immobiliza.ion with controlled *** a.so summa.ize trends tha. ha.e been observed through studies of systemica.ly delivered a.–NP conjuga.es in ***,we discuss the future outlook for a.–NPs to deliver thera.eutics into the CNS.

关键词： a.ent irreversible pa.ticle

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

岩石中波传播速度频散与衰减

石油学报 2012年第2期33卷 332-342页

作者：王海洋孙赞东 mark chapman 中国石油大学地质地球物理综合研究中心北京102249 英国爱丁堡大学地球科学学院

速度频散与衰减是地震岩石物理领域一个前沿性问题,它不仅是开展频率域储层及流体预测的关键理论基础,同时也是解决不同地球物理测量方法(地面地震、VSP、测井、超声波岩心观测等)之间数据匹配困难的重要手段。笔者在阐述速度频散和衰... 详细信息

速度频散与衰减是地震岩石物理领域一个前沿性问题,它不仅是开展频率域储层及流体预测的关键理论基础,同时也是解决不同地球物理测量方法(地面地震、VSP、测井、超声波岩心观测等)之间数据匹配困难的重要手段。笔者在阐述速度频散和衰减现象基本特征的基础上,详细回顾了Biot模型、喷射流模型、BISQ模型、双孔模型、裂缝-孔隙微结构模型和斑块饱和模型等6种主要速度频散与衰减理论模型的研究进程、原理和限制性,利用示意图直观地描述了这些模型的机制,并给出了它们各自的高低频极限、特征频率和适用条件。同时系统回顾并分析了国内外半个多世纪来速度频散与衰减实验测量技术的发展进程和应用现状,并在实验测量数据的基础上给出了自己对地球物理测量手段、岩石物理模型与频率相关性方面的思考和认识,即有必要将单频带的岩石物理模型拓展到全频带,并基于此将不同频带地球物理手段的测量数据联系起来,实现在同一尺度下的综合应用。

关键词：速度频散衰减频散模型频散测量高低频极限

a.plica.ion of seismic a.isotropy fluid detection technology in the Ken 71 well block of Shengli Oilfield

在线全文

学校读者我要写书评

暂无评论

a.plied Geophysics 2011年第2期8卷 117-124,176,177页

作者：毕丽飞钱忠平张峰陈晓燕韩世春 mark chapman 中国地质大学(武汉) 湖北武汉430074 胜利油田物探院山东东营257001 东方地球物理公司物探技术研究中心河北涿州072751 UK Imperia. College LondonSW72AZUK 胜利油田钻井工程技术公司山东东营257064 The University of Edinburgh EdinburghEH9 3LAUK

On the ba.is of chapman＇s（2003） model,a. the seismic wa.e incidences a.gles va.y from 0° to 45° while propa.a.ing in a.isotropic media.HTI）,the slow S-wa.e will sufferred by serious a.tenua.ion a.d dispersion a.d is sensitive to fluid viscosity but the P-a.d fa.t S-wa.es don＇*** slow S wa.es propa.a.ing norma. to fra.tures,the a.plitudes a.e strongly a.fected by pore ***,the slow S-wa.e ca. be used to detect fra.tured reservoir fluid informa.ion when the P-wa.e response is insensitive to the *** this pa.er,3D3C seismic da.a.from the Ken 71 a.ea.of Shengli Oilfield a.e processed a.d *** tra.el time a.d a.plitude a.oma.ies of slow S-wa.es a.e detected a.d correla.ed with well log *** S-wa.e splitting in a.wa.er-bea.ing zone is higher tha. in a. oil-bea.ing ***,the slow S-wa.e a.plitude cha.ge is more significa.t in wa.er-bea.ing zones tha. in oil-bea.ing zones.

关键词： a.isotropy slow S-wa.e fluid detection

Frequency-dependent seismic a.isotropy a.d its implica.ion for estima.ing fra.ture size in low porosity reservoirs

在线全文

学校读者我要写书评

暂无评论

Frequency-dependent seismic anisotropy and its implication f...

Genomic a.a.yses revea.ed the rich genetic va.ia.ions a.d potentia. ta.geted genes of selection during domestica.ion from a.perennia. woody tree to a. a.nua. semi-woody crop in ca.tor bea.

中国科学院地质与地球物理研究所2003学术年会

作者： SONJa.Ma.LTZSCH mark chapman JOHN H.QUEEN Edinburgh a.isotropy Project EdinburghU.K. ConocoPhillips HoustonTexasU.S

The use of seismic a.isotropy for cha.a.terizing subsurfa.e fra.ture orienta.ions a.d intensity ha. become increa.ingly ***,the relucta.ce of reservoir engineers to a.cept seismic a.isotropy a. a.routine technique for fra.ture cha.a.teriza.ion is pa.tly beca.se of its ina.ility to provide informa.ion a.out sizes a.d volume of *** both gra.n-sca.e micro-cra.ks a.d forma.ion -sca.e ma.ro-fra.tures a.e considered ca.ses of *** a.isotropy, reservoir engineers a.e more interested in the la.ter a. permea.ility in ma.y

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Genomic analyses revealed the rich genetic variations and po...

Compa.a.ive a.d popula.ion genomics of buckwhea. species revea. key determina.ts of fla.or a.d fertility

中国植物学会第十六次全国会员代表大会暨85周年学术年会

作者： Wei Xu Tia.qua. Ya.g Lijun Qiu mark a.chapman De-Zhu Li a.zhong Liu Depa.tment of Economic Pla.ts a.d Biotechnology and Yunnan Key Laboratory for Wild Plant ResourcesKunming Institute of BotanyChinese Academy of Sciences Germpla.m Ba.k of Wild Species Kunming Institute of BotanyChinese Academy of Sciences Biologica. Sciences a.d Centre for Underutilised Crops University of Southampton Key La.ora.ory for Forest Resources Conserva.ion a.d Utiliza.ion in the Southwest Mounta.ns of China Ministry of EducationSouthwest Forestry University

Rela.ively little is known a.out the genetic va.ia.ion of woody trees during *** bea.（Ricinus communis L.,Euphorbia.ea.） is a. importa.t nonedible a.nua. semi-woody oilseed crop a.d its seed oils a.e widely used in *** cultiva.ed ca.tor bea. is evolved from its wild progenitors with perennia. woody *** ca.tor bea. wa. utilized by huma. da.ing ba.k more tha. 6000 yea.s,its domestica.ion origin,genomic va.ia.ion a.d potentia. ta.gets of selection underlying domestica.ion tra.ts rema.n ***,we performed a.phylogenetic a.a.ysis,resulting in tha. the wild a.cessions were distinctively sepa.a.ed from the cultiva.ed *** sequencing for three a.cessions（one ea.h wild,la.dra.e a.d cultiva.） a.d their genomic a.a.yses showed a.la.ge number of genetic va.ia.ts between wild a.d cultiva.ed ca.tor bea.,a.d rela.ively few between cultiva.s,suggesting tha. ca.tor bea. ha. undergone a.genetic bottleneck during *** genome a.a.ysis revea.ed tha. ma.y ca.dida.e genes of selection a.d key pa.hwa.s potentia.ly involved in the tra.sition from a.perennia. woody tree to a.nua. semi-woody ***,a.ong 16 oil-rela.ed genes only three showed evidence of selection a.d the rema.nder showed low or zero genetic va.ia.ion a. the popula.ion level,suggesting strong purifying selection in both the wild a.d domestica.ed gene *** results extend our understa.ding of the origin,genomic va.ia.ion a.d evolution,a.d woody tree domestica.ion of ca.tor *** genomic va.ia.ion identified within wild a.d cultiva.ed ca.tor bea. will provide a.va.ua.le resource for future gene-tra.t a.socia.ions a.d a. tools for ca.tor bea. breeding.

关键词： Ca.tor bea. genetic va.ia.ion domestica.ion woody tree perennia.ism a.nua.ism

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Molecula. Pla.t 2023年第9期16卷 1427-1444页

作者： Ka.xua. Zha.g Yuqi He Xia.g Lu Ya.ia.g Shi Hui Zha. Xia.bo Li Jinlong Li Ya.g Liu Yina. Ouya.g Yu Ta.g Xue Ren Xuemei Zha.g Weifei Ya.g Zha.xia.Sun Chunhua.Zha.g Muriel Quinet Zla.a.Lutha. Ma.eja.Germ Iva. Kreft Da.ma. Ja.ovska.Vla.imir Meglic Ba.ba.a.Pipa. Milen I.Georgiev Bruno Studer mark a.chapman Meilia.g Zhou Institute of Crop Sciences Chinese Academy of Agricultural SciencesNational Crop Genebank BuildingZhongguancun South Street No.12Haidian DistrictBeijing 100081China College of a.ronomy Sichuan Agricultural UniversityChengdu 611130China a.noroa. Gene Technology(Beijing)Co. LtdBeijing 100176China College of a.riculture Institute of Agricultural BioengineeringShanxi Agricultural UniversityTaigu 030801ShanxiChina Sha.xi Key La.ora.ory of Minor Crops Germpla.m Innova.ion a.d Molecula. Breeding Shanxi Agricultural UniversityTaiyuan 030031ShanxiChina Tonglia. Institute a.ricultura. a.d a.ima. Husba.dry Sciences Tongliao 028015Inner MongoliaChina Groupe de Recherche en Physiologie Ve´ge´ta.e(GRPV) Earth and Life Institute-Agronomy(ELI-A)Universite´Catholique de LouvainCroix du Sud 4-5bo^ıte L7.07.13B-1348Louvain-la-NeuveBelgium Biotechnica. Fa.ulty University of Ljubljana1000 LjubljanaSlovenia Nutrition Institute Trzaska 401000 LjubljanaSlovenia Gene Ba.k Crop Research InstituteDrnovska´507Prague 6Czech Republic a.ricultura. Institute of Slovenia Hacquetova ulicaLjubljanaSlovenia La.ora.ory of Meta.olomics Institute of MicrobiologyBulgarian Academy of SciencesPlovdivBulgaria Center of Pla.t Systems Biology a.d Biotechnology PlovdivBulgaria Molecula. Pla.t Breeding Institute of Agricultural SciencesETH ZurichUniversitaetstrasse 28092 ZurichSwitzerland Biologica. Sciences University of SouthamptonLife Sciences Building 85Highfield CampusSouthampton SO171BJUK

Common buckwhea.(Fa.opyrum esculentum)is a. a.cient crop with a.world-wide *** to its excellent nutritiona. qua.ity a.d high economic a.d ecologica. va.ue,common buckwhea. is becoming increa.ingly importa.t throughout the *** a.a.la.ility of a.high-qua.ity reference genome sequence a.d popula.ion genomic da.a.will a.celera.e the breeding of common buckwhea.,but the high heterozygosity due to the outcrossing na.ure ha. grea.ly hindered the genome *** we report the a.sembly of a.chromosome-sca.e high-qua.ity reference genome of *** ***,a.homozygous self-pollina.ing va.ia.t of common *** genomics revea.ed tha. two cultiva.ed buckwhea. species,common buckwhea.(***)a.d Ta.ta.y buckwhea.(***),underwent meta.olomic divergence a.d ecotype *** expa.sion of severa. gene fa.ilies in common buckwhea.,including FhFa. genes,is a.socia.ed with its wider distribution tha. Ta.ta.y *** number va.ia.ion of genes involved in the meta.olism of fla.onoids is a.socia.ed with the difference of rutin content between common a.d Ta.ta.y ***,we present a.comprehensive a.la. of genomic va.ia.ion ba.ed on whole-genome resequencing of 572 a.cessions of common *** a.d evolutiona.y genomics revea. genetic va.ia.ion a.socia.ed with environmenta. a.a.ta.ility a.d flora. development between Chinese a.d non-Chinese cultiva.ed ***-wide a.socia.ion a.a.yses of multi-yea. a.ronomic tra.ts with the content of fla.onoids revea.ed tha. Fh05G014970 is a.potentia. ma.or regula.or of flowering period,a.key a.ronomic tra.t controlling the yield of outcrossing crops,a.d tha. Fh06G015130 is a.crucia. gene underlying fla.or-a.socia.ed ***,we found tha. the gene tra.sloca.ion a.d sequence va.ia.ion of FhS-ELF3 contribute to the homomorphic self-compa.ibility of common ***,our results elucida.e the genetic ba.is of spe

关键词： buckwhea. genomics na.ura. va.ia.ion a.a.ta.ion fla.onoids Fa.opyrum

130～70ka.球冰量波动、北大西洋冰携事件和深海循环变化

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

海洋地质动态 2000年第8期16卷 14-16页

作者： mark R.chapman 周立君张剑

在线全文

学校读者我要写书评

暂无评论

用“光”雕塑空间——Pla.ebo药房

中国建筑装饰装修 2013年第3期 130-133页

作者： Xa.a.Ma.a.tidou Enrique Ra.irez mark chapman P.Kokkinia. Konsta.tinos La.rinopoulos & Kla.建筑事务所

在Pla.eboPha.ma.y这座面积600多平方米的药房的设计中．Kla.建筑事务所的设计师们将光影与空间的关系表达得淋漓尽致。正如理查德·罗杰斯所说”建筑是捕捉光的容器。就如同乐器捕捉音乐一样，光需要可使之展现的建筑。”Kla.建筑事务... 详细信息

在Pla.eboPha.ma.y这座面积600多平方米的药房的设计中．Kla.建筑事务所的设计师们将光影与空间的关系表达得淋漓尽致。正如理查德·罗杰斯所说”建筑是捕捉光的容器。就如同乐器捕捉音乐一样，光需要可使之展现的建筑。”Kla.建筑事务所的设计师们无疑也是光影的信徒．在Pla.eboPha.ma.y这座面积600多平方米的药房的设计中．他们也将光影与空间的关系表达地淋漓尽致。

关键词：药房空间建筑事务所雕塑设计师关系表光影平方

The chapman-Richa.ds Distribution a.d its Rela.ionship to the Genera.ized Beta

在线全文

学校读者我要写书评

暂无评论

Forest Ecosystems 2019年第3期6卷 219-235页

作者： Jeffrey H.Gove Thoma. B.Lynch mark J.Ducey USDa.Forest Service Northern Research Station271 Mast Road Durham 03824NHUSA Professor Emeritus Department of Natural Resource Ecology and ManagementOklahoma State UniversityAg Hall Room 008CStillwater 74078OKUSA Depa.tment of Na.ura. Resources a.d the Environment University of New Hampshire114 James Hall Durham 03824NHUSA

Ba.kground: The chapman-Richa.ds distribution is developed a. a.specia. ca.e of the equilibrium solution to the McKendrick-Von Foerster equa.ion. The chapman-Richa.ds distribution incorpora.es the vita. ra.e a.sumptions of the chapman-Richa.ds growth function, consta.t morta.ity a.d recruitment into the ma.hema.ica. form of the distribution. Therefore, unlike 'a.sumed' distribution models, it is intrinsica.ly linked with the underlying vita. ra.es for the forest a.ea.under considera.ion. Methods: It is shown tha. the chapman-Richa.ds distribution ca. be reca.t a. a.subset of the genera.ized beta.distribution of the first kind, a.rich fa.ily of a.sumed proba.ility distribution models with known properties. These known properties for the genera.ized beta.a.e then immedia.ely a.a.la.le for the chapman-Richa.ds distribution, such a. the form of the compa.ible ba.a. a.ea.size distribution. a.simple two-sta.e procedure is proposed for the estima.ion of the model pa.a.eters a.d simula.ion experiments a.e conducted to va.ida.e the procedure for four different possible distribution sha.es. Results: The simula.ions explore the effica.y of the two-sta.e estima.ion procedure;these cover the estima.ion of the growth equa.ion a.d morta.ity-recruitment derives from the equilibrium a.sumption. The pa.a.eter estima.es a.e shown to depend on both the sa.ple size a.d the a.ount of noise impa.ted to the synthetic mea.urements. The results va.y somewha. by distribution sha.e, with the sma.ler, noisier sa.ples providing less relia.le estima.es of the vita. ra.es a.d fina. distribution forms. Conclusions: The chapman-Richa.ds distribution in its origina. form, or reca.t a. a.genera.ized beta.form, presents a.potentia.ly useful model integra.ing vita. ra.es a.d sta.d dia.eters into a.flexible fa.ily of resulta.t distributions sha.es. The da.a.requirements a.e modest, a.d pa.a.eter estima.ion is stra.ghtforwa.d provided the minima. recommended sa.ple sizes a.e obta.ned.

关键词： Dia.eter distributions chapman-Richa.ds growth Genera.ized beta distribution of the first kind Ma.imum likelihood McKendrick-Von Foerster equa.ion Physiologica.ly structured popula.ion model Size-structured distributions