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Worldwide trends in esophageal cancer survival,by sub-site,morphology,and sex:an analysis of 696,974 adults diagnosed in 60 countries during 2000-2014(CONCORD-3)

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Cancer Communications 2023年第9期43卷 963-980页

作者： Melissa Matz Mikhail Valkov mario Šekerija Sabine Luttman Adele Caldarella Michel P Coleman Claudia Allemani the CONCORD Working Group Cancer Survival Group Department of Non-Communicable Disease EpidemiologyLondon School of Hygiene and Tropical MedicineLondon WC1E 7HTGreater LondonUnited Kingdom Department of Radiology Radiotherapy and OncologyNorthern State Medical UniversityArkhangelskArkhangelsk OblastRussia Croatian National Cancer Registry Croatian Institute of Public HealthZagrebZagreb CountyCroatia Bremen Cancer Registry BremenBremenGermany Tuscany Cancer Registry Istituto per lo studio e la prevenzione oncologicaFlorenceTuscanyItaly Cancer Division University College London Hospitals NHS Foundation TrustLondon NW1 2BUGreater LondonUnited Kingdom Members listed at the end of the article

Background Esophageal cancer survival is poor worldwide,though there is some *** in the distribution of anatomical sub-site and morphological sub-type may help explain international differences in survival for all esophageal cancers *** estimated survival by anatomic sub-site and morphological sub-type to understand further the impact of topography and morphology on international comparisons of esophageal cancer *** We estimated age-standardized one-year and five-year net survival among adults(15-99 years)diagnosed with esophageal cancer in each of 60 participating countries to monitor survival trends by calendar period of diagnosis(2000-2004,2005-2009,2010-2014),sub-site,morphology,and *** For adults diagnosed during 2010-2014,tumors in the lower third of the esophagus were the most common,followed by tumors of overlapping sub-site and sub-site not otherwise *** proportion of squamous cell carcinomas diagnosed during 2010-2014 was generally higher in Asian countries(50%-90%),while adenocarcinomas were more common in Europe,North America and Oceania(50%-60%).From 2000-2004 to 2010-2014,the proportion of squamous cell carcinoma generally decreased,and the proportion of adenocarcinoma *** time,there were few improvements in age-standardized five-year survival for each ***-standardized one-year survival was highest in Japan for both squamous cell carcinoma(67.7%)and adenocarcinoma(69.0%),ranging between 20%-60%in most other ***-standardized five-year survival from squamous cell carcinoma and adenocarcinoma was similar for most countries included,around 15%-20%for adults diagnosed during 2010-2014,though international variation was wider for squamous cell *** most countries,survival for both squamous cell carcinoma and adenocarcinoma increased by less than 5%between 2000-2004 and *** Esophageal cancer survival remains poor in many *** distributions

关键词： Cancer esophagus morphology survival topography trends

Estimating the Lost Economic Production Caused by Internal Displacement Because of Disasters

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International Journal of Disaster Risk Science 2018年第4期9卷 496-506页

作者： mario A.Salgado-Gálvez Centre Internacional de Metodes Numerics en Enginyeria(CIMNE) 08034 BarcelonaSpain

Disasters are a large cause of internal displacement at the global level, in 2017 alone affecting more than19 million people. This dimension of disaster risk is usually overlooked in many disaster risk management strategies and assessments. It is only very recently that efforts to quantify displacement risk and integrate that dimension into existing physical risk models have been made. A key component of internal displacement assessment is the quantification of its economic impacts, both direct and indirect, not only to make a figure available but to raise awareness and increase accountability among governments, stakeholders, policymakers, and decision *** article presents a novel and peril-agnostic methodology with which to estimate, using a scenario-based approach, the economic production lost because of internal population displacement. The methodology is applied by using as a triggering event the April 2015 Gorkha, Nepal M7.8 earthquake. The method quantifies the indirect cost caused by internal population displacement because of that event in terms of lost economic production and estimates the loss to be between USD 400 and 850 million.

关键词： Disability adjusted life years Disaster risk Internally displaced people Lost economic production Disaster risk assessment

Avian preference for close proximity to human habitation and its ecological consequences

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Current Zoology 2018年第5期64卷 623-630页

作者： Anders Pape MOLLER mario DiAZ Ecologie Systematique Evolution CNRS Universite Paris-Sud AgroParisTech Universite Pari-Saclay 0rsay Cedex F-91400 France Department of Biogeography and Global Change (BGC-MNCN-CSIC) National Museum of Natural Sciences CSIC c/Serrano 155bis Madrid E-28006 Spain

Human proximity often have negative consequences for wildlife. However, animals may also benefit from human proximity in terms of availability of resources and protection against predators and parasites. We recorded the distance between all birds detected during the breeding season along 18 5-km transects and the nearest inhabited house in three areas of 50 km in Spain, France, and Denmark. More than three quarters of birds were located closer than 100 m to the nearest house, while the null expectation was less than a third. Mean distance for species was correlated with degree of bird urbanization and with flight initiation distance. Habitat specialist species with small breeding territories tended to live closer to houses. Birds from species having more broods per year, larger annual fecundity and lower nest predation rate lived closer to human habitation. Breeding range size, population density, and continental breeding population sizes were larger for species living closer to human habitation. Most relationships between distance to houses and bird traits had a strong phylogenetic signal, but most additive trait effects remained after phylogenetic correction. Proximity to human habitation was a main driver of the distribution of birds, with most individuals and species tightly linked to inhabited houses. Living close to human habitation was associated with success in the colonization of urban habitats and with consistent changes in distribution, abundance, behavior, and life history. Replicated measurements of the spatial and temporal variation in these distributions may be useful for monitoring and analyzing the ongoing process of organisms' urbanization.

关键词：居住鸟偏爱生态繁殖季节野生动物人口密度种系发生

The impact of ancestral population size and incomplete lineage sorting on Bayesian estimation of species divergence times

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Current Zoology 2015年第5期61卷 874-885页

作者： Konstantinos ANGELIS mario DOS REIS Department of Genetics Evolution and Environment University College London Gower Street London WC 1E 6BT UK

Although the effects of the coalescent process on sequence divergence and genealogies are well understood, the virtual majority of studies that use molecular sequences to estimate times of divergence among species have failed to account for the coalescent process. Here we study the impact of ancestral population size and incomplete lineage sorting on Bayesian estimates of species divergence times under the molecular clock when the inference model ignores the coalescent process. Using a combination of mathematical analysis, computer simulations and analysis of real data, we find that the errors on estimates of times and the molecular rate can be substantial when ancestral populations are large and when there is substantial incomplete lineage sorting. For example, in a simple three-species case, we find that if the most precise fossil calibration is placed on the root of the phylogeny, the age of the internal node is overestimated, while if the most precise calibration is placed on the internal node, then the age of the root is underestimated. In both cases, the molecular rate is overestimated. Using simulations on a phylogeny of nine species, we show that substantial errors in time and rate estimates can be obtained even when dating ancient divergence events. We analyse the hominoid phylogeny and show that estimates of the neutral mutation rate obtained while ignoring the coalescent are too high. Using a coalescent-based technique to obtain geological times of divergence, we obtain estimates of the mutation rate that are within experimental estimates and we also obtain substantially older divergence times within the phylogeny.

关键词：贝叶斯估计分歧时间物种分化谱系种群大小祖先排序不完全

A case of obstructive azoospermia secondary to genitourinary tract infection caused by a prostatic utricle cyst

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Asian Journal of Andrology 2022年第5期24卷 558-559页

作者： Tomoki Saito Mitsuru Komeya Kimitsugu Usui Shinnosuke Kuroda Teppei Takeshima Kunitomo Takashima mario Ikeda Yoshihito Kondo Yasushi Yumura Department of Urology Yokohama City University Medical Center4-57 Urafune-choMinami-kuYokohama CityKanagawa 232-0024Japan Department of Urology Yokohama City University Graduate School of Medicine3-9 FukuuraKanazawa-kuYokohama CityKanagawa 236-0004Japan Ebina Ladies Clinic 3-3-1 ChuoEbina CityKanagawa 243-0432Japan

Dear Editor,Obstructive azoospermia(OA)is defined as the absence of spermatozoa in the sediment of a centrifuged sample of ejaculate and is usually caused by an obstruction anywhere along the posttesticular *** is diagnosed in 20%–40%of men with *** OA may be acquired congenitally,such as in Young’s syndrome that presents with bilateral vas deferens abnormalities,it commonly develops as a sequela of prostatic and ejaculatory duct cysts,childhood inguinal hernias,epididymitis,and vasectomy.

关键词： prostatic azoospermia urinary

Applying rock mass classifications to carbonate rocks for engineering purposes with a new approach using the rock engineering system

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 364-369页

作者： Gioacchino Francesco Andriani mario Parise Dipartimento di Scienze della Terra e Geoambientali Università degli Studi di Bari Aldo MoroVia E. Orabona n. 4Bari 70125Italy

Classical rock mass classification systems are not applicable to carbonate rocks,especially when these are affected by karst *** applications to such settings could therefore result in outcomes not representative of the real stress-strain *** this study,we propose a new classification of carbonate rock masses for engineering purposes,by adapting the rock engineering system(RES) method by Hudson for fractured and karstified rock masses,in order to highlight the problems of implementation of geomechanical models to carbonate *** new approach allows a less rigid classification for carbonate rock masses,taking into account the local properties of the outcrops,the site conditions and the type of engineering work as well.

关键词： Rock mass classification Carbonates Karst Rock engineering system(RES)

Heterogeneous catalysis under flow for the 21st century fine chemical industry

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Green Energy & Environment 2021年第2期6卷 161-166页

作者： Rosaria Ciriminna mario Pagliaro Rafael Luque Istituto per Io Studio dei Mate riali Nanostnuturati CNRwia U.La Malfa 15390146PulemoItaly Deparamento de Quimica Orginica Univeridad de CordobaCampus de RabonalesEdificio Marie Curie(C-3)Cra Nnal IV-Akm 396Cordoba14014Spain Peoples Friendship University of Russia(RUDN Universiy) 6 Miklukho Maklaya St117198MoscowRussia

Due to metal leaching and poor catalyst stability, the chemical industry's fine chemical and pharmaceutical sectors have been historically reluctant to use supported transition metal catalysts to manufacture fine chemicals and active pharmaceutical ingredients. With the advent of new generation supported metal catalysts and flow chemistry, we argue in this study, this situation is poised to quickly change. Alongside heterogenized metal nanoparticles, both single-site molecular and single-atom catalyst will become ubiquitous. This study offers a critical outlook taking into account both technical and economic aspects.

关键词： Fine chemical Heterogeneous catalysis Single atom catalysis Green chemistry Chemical industry

Both comorbidity burden and low testosterone can explain symptoms and signs of testosterone deficiency in men consulting for sexual dysfunction

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Asian Journal of Andrology 2020年第3期22卷 265-273页

作者： Giulia Rastrelli Giovanni Corona mario Maggi Sexual Medicine and Andrology Unit Department of Experimental and Clinical Biomedical SciencesUniversity of FlorenceViale Pieraccini 6Florence 50139Italy Endocrinology Unit Medical DepartmentMaggiore-Bellaria HospitalLargo Nigrisoli 2Bologna 40133Italy I.N.B.B. Biostructures and Biosystems National InstituteViale delle Medaglie d'Oro 305Rome(X)136Italy Endocrinology Unit Department of Experimental Clinical and Biomedical Sciences**Mario Serio"University of FlorenceViale Pieraccini 6Florence 50139Italy.

Low testosterone(T)is frequent in men with chronic *** clinical features of T deficiency(TD)overlap with those of chronic *** aim of this study is to evaluate the relative contribution of chronic disease score(CDS)and low T to the presenee of TD symptoms.A consecutive series of 3862 men(aged 52.1±13.1 years)consulting for sexual dysfunction were *** clinical and biochemical parameters were collected,in eluding the structured interview,ANDROTEST,for the assessme nt of TD *** color Doppler ultrasound(PCDU)was also *** on the medications taken,the CDS was *** a subset of 1687 men,information on mortality was collected(follow-up of 4.3±2.6 years).Higher CDS was associated with lower free and total T(TT)as well as with higher ANDROTEST *** introducing CDS and TT in multivariable models adjusted for age,severe erectile dysfunctio n and impaired morning erectio ns were associated with both CDS(odds ratio and 95%confide nee interaval,OR[95%Cl]=1.25[1.13;1.37]and 1.38[1.29;1.48],respectively)and low TT(OR[95%Cl]=1.11[1.00;1.23]and 1.13[1.06;1.21],respectively).Similar results were obtained for PCDU *** sexual desire was associated with low TT(OR[95%Cl]=1.21[1.13;1.30]),whereas it was inversely related with CDS(OR[95%Cl]=0.91[0.84;0.97]).When considering mortality for major cardiovascular events,TT<8 nmol I1,but not CDS,was a significant predictor(hazard ratio[95%Cl]=5.57[1.51;20.63]).Chronic illnesses are associated with an overt *** chronic diseases and low T can be invoIved in determining symptoms present in subjects complaining for sexual *** should be considered in the diagnostic workup for TD.

关键词： chronic diseases erectile dysfunction sexual symptoms testosterone deficiency

Investigation of radial heat conduction with 1D self-consistent model in helicon plasmas

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Plasma Science and Technology 2023年第1期25卷 28-42页

作者：田滨 mario MERINO 万杰胡远曹勇 School of Mechanical Engineering and Automation Harbin Institute of TechnologyShenzhenShenzhen 518055People's Republic of China Equipo de Propulsión Espacial y Plasmas EP2 Universidad Carlos Ⅲ de MadridLeganés 28911Spain Laboratory for Space Environment and Physical Sciences Harbin Institute of TechnologyHarbin 150001People's Republic of China State Key Laboratory of High Temperature Gas Dynamics Institute of MechanicsChinese Academy of SciencesBeijing 100190People's Republic of China

A 1D radially self-consistent model in helicon plasmas has been established to investigate the influence of radial heat conduction on plasma transport and wave *** kinds of 1D radial fluid models,with and without considering heat conduction,have been developed to couple the 1D plasma-wave interaction model,and self-consistent solutions have been *** is concluded that in the low magnetic field range the radial heat conduction plays a moderate role in the transport of helicon plasmas and the importance depends on the application of the helicon *** influences the local energy balance leading to enhancement of the electron temperature in the bulk region and a decrease in plasma *** power deposition in the plasma is mainly balanced by collisional processes and axial diffusion,whereas it is compensated by heat conduction in the bulk region and consumed near the *** role of radial heat conduction in the large magnetic field regime becomes negligible and the two fluid models show *** local power balance,especially near the wall,is improved when conductive heat is taken into account.

关键词： helicon discharge heat conduction model coupling plasma transport