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Gut microbiota in preterm infants receiving breast milk or mixed feeding

World Journal of Clinical Pediatrics 2024年第2期13卷 135-145页

作者： sandra Gabriela sánchez-gonzález Bárbara Gabriela Cárdenas-del-Castillo Elvira Garza-gonzález Gerardo R Padilla-Rivas Isaías Rodríguez-Balderrama Consuelo Treviño-Garza Fernando Félix Montes-Tapia Gerardo C Palacios-saucedo Anthony Gutiérrez-Rodríguez Manuel Enrique de-la-O-Cavazos Department of Pediatrics Hospital Universitario“Dr.JoséEleuterio González”Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Departamento de Bioquímica y Medicina Molecular Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Department of Biochemistry and Molecular Medicine Universidad Autónoma de Nuevo LeónMonterrey 64460Nuevo LeónMéxico Department of Pediatric surgery Hospital Universitario"Dr.JoséEleuterio González"Monterrey 64460Nuevo LeónMéxico

BACKGROUND Preterm birth is the leading cause of mortality in newborns,with very-low-birthweight infants usually experiencing several *** milk is considered the gold standard of nutrition,especially for preterm infants with delayed gut colonization,because it contains beneficial microorganisms,such as Lactobacilli and *** To analyze the gut microbiota of breastfed preterm infants with a birth weight of 1500 g or *** An observational study was performed on preterm infants with up to 36.6 wk of gestation and a birth weight of 1500 g or less,born at the University Hospital ***éEleuterio gonzález at Monterrey,Mexico.A total of 40 preterm neonates were classified into breast milk feeding(BM)and mixed feeding(MF)groups(21 in the BM group and 19 in the MF group),from October 2017 to June *** samples were collected before they were introduced to any feeding *** full enteral feeding was achieved,the composition of the gut microbiota was analyzed using 16s rRNA gene *** variables were compared using student’s t-test or using the Mann–Whitney U test for nonparametric ***,evenness,equitability,Margalef’s index,Fisher’s alpha,chao-1 index,and shannon’s diversity index were also *** No significant differences were observed at the genus level between the *** comparison indicated higher counts of Alphaproteobacteria and Betaproteobacteria in the initial compared to the final sample of the BM group(Ps of Gammaproteobacteria were detected in the final than in the initial sample(P=0.040).According to the Margalef index,Fisher’s alpha,and chao-1 index,a decrease in species richness from the initial to the final sample,regardless of the feeding type,was observed(Ps,Actinobacteria,Firmicutes,and Proteobacteria,with Proteobacteria being the most ***,no significant differences were

关键词： Gut microbiota Human milk Preterm infant Proteobacteria Very low birth weight 16s rRNA

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Revisiting the theoretical prediction of the explosive performance found by the Trauzl test

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Defence Technology（防务技术） 2024年第6期36卷 163-174页

作者： Ivana Dobrilovic mario Dobrilovic Muhamed suceska Faculty of Mining Geology and Petroleum EngineeringDepartment of Mining Engineering and GeotechnicsUniversity of ZagrebPierottijeva 6Zagreb10000Croatia

The Trauzl lead block test allows the determination of the approximate performance of explosives in blasting applications by measuring the volume increase(expansion)that is produced by the detonation of an explosive charge in the cavity of a lead *** this paper,we reconsider the possibility of interpreting the Trauzl test results in terms of detonation parameters or *** detonation parameters used in the analysis are calculated using the thermochemical code EXPLO5,while the hydrocode AUTODYN is used to simulate the effect of explosive charge density and reaction rate on the results of the Trauzl *** increase in the volume of the lead block cavity was found to correlate best with the product of the detonation heat and the root of the volume of detonation *** simulation showed that the density of explosive charge and the rate of explosive decomposition affect the dynamics of the interaction of the detonation product and the lead block,and consequently the lead block cavity volume increase.

关键词： Trauzl lead block test Performance of explosives EXPLO5 AUTODYN Detonation heat

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Impact of payment source, referral site, and place of residence on outcomes after allogeneic transplantation in Mexico

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World Journal of Transplantation 2024年第2期14卷 76-87页

作者： andrés Gómez-De León Yesica A López-Mora Valeria García-Zárate Ana Varela-Constantino sergio U Villegas-De Leon Xitlaly J gonzález-Leal Raúl del Toro-Mijares Anna C Rodríguez-Zúñiga Juan F Barrios-Ruiz Victor Mingura-Ledezma Perla R Colunga-Pedraza Olga G Cantú-Rodríguez César H Gutiérrez-Aguirre Luz Tarín-Arzaga Elías E gonzález-López David Gómez-Almaguer Hematology service Universidad Autónoma de Nuevo LeónFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezMonterrey 64460Nuevo LeónMexico Hemato-logy service Clínica Gómez AlmaguerMonterrey 64710Nuevo LeónMexico Hematology service Instituto Tecnológico de Estudios Superiores de MonterreyTec SaludEscuela de Medicina Ignacio SantosMonterrey 64710Nuevo LeónMexico

BACKGROUND The impact of social determinants of health in allogeneic transplant recipients in low-and middle-income countries is poorly *** observational study analyzes the impact of place of residence,referring institution,and transplant cost coverage(out-of-pocket vs government-funded vs private insurance)on outcomes after allogeneic hematopoietic stem cell transplantation(alloHsCT)in two of Mexico's largest public and private *** To evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transplant recipients in *** In this retrospective cohort study,we included adolescents and adults≥16 years who received a matched sibling or haploidentical transplant from *** were selected without regard to their diagnosis and were sourced from both a private clinic and a public University Hospital in *** payment groups were compared:Out-of-pocket(OOP),private insurance,and a federal Universal healthcare program“seguro Popular”.Outcomes were compared between referred and institution-diagnosed patients,and between residents of Nuevo Leon and *** outcomes included overall survival(Os),categorized by residence,referral,and payment *** outcomes encompassed early mortality,event-free-survival,graft-versus-host-relapse-free survival,and non-relapse-mortality(NRM).statistical analyses employed appropriate tests,Kaplan-Meier method,and Cox proportional hazard regression *** software included sPss and R with tidycmprsk *** Our primary outcome was overall *** included 287 patients,n=164 who lived out of state(57.1%),and n=129 referred from another institution(44.9%).The most frequent payment source was OOP(n=139,48.4%),followed by private insurance(n=75,26.1%)and universal coverage(n=73,25.4%).No differences in Os,event-free-survival,NRM,or graft-versus-host-relapse-free survival were observed for patients dia

关键词： Hematopoietic cell transplant social determinants of health Geography Haploidentical Out-of-pocket Financial toxicity survival Health services and outcomes Hematopoietic malignancy Aplastic anemia

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solid-liquid extraction for yttrium recovery using porous polymeric resin（XAD-7） functionalized with D2EHPA

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Journal of Rare Earths 2024年第9期42卷 1764-1773页

作者： P.A.Martínez-Montoya R.G.sanchez-Alvarado D.Y.Medina-Velazquez M.L.Carrera-Jota P.Garnica-chávez A.de J.Morales-Ramirez Higher school of chemical Engineering and Extractive Industries ESIQIEIPNDepartment of Metallurgical Engineering Metropolitan Autonomous University Department of MaterialsBasic Sciences and Engineering Center for Research and Technological Innovation CIITECIPN

The recovery of yttrium is proposed by applying a solid-liquid extraction process using di-2-ethyl hexylphosphoric acid（D2EHPA） as extracting *** extracting agents were supported on a macro porous polymeric resin XAD-7（solid phase）.Yttrium ions extraction and discharge tests were performed,firstly from a synthetic aqueous solution of 100 mg/L Y（liquid phase） at 25℃ with *** effects of pH of aqueous solutions bearing yttrium,volume fraction of extracting agents and the solid/liquid（s/L）ratio on the yttrium recovery were *** most favorable conditions for yttrium ions extraction are;20 vol% D2EHPA functionalized resin,pH=1.5 and an s/L ratio of 10 mg/mL The discharge of yttrium ions was done under the same conditions of extraction stage,using a 2 mol/L [H2sO4] as stripping *** to 80% yttrium is extracted,while 75% yttrium is recovered in the striping *** all experiments,the reaction equilibrium is reached after 20 min,and the kinetics for the extraction stage was determined as a second-order ***,experiments were carried out to discharge the yttriumloaded resins,and it has been determined that the best pH value to strip the Y ions is *** tests of extraction and discharge for yttrium ions show that the functionalized resin can work at least five cycles without decreasing its ***,the proposed process was tested in a real solution with Y ions fro m a waste fluorescent la mp powder leached in H2sO4,demonstrating the ability to effectively recover yttrium,separating it from various metals from the studied residue.

关键词： Fluorescent lamps recycling Rare earth solid-liquid extraction solid-liquid kinetics extraction XAD-7 resin Yttrium recovery

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Developing biophilic intermediate spaces for Arctic housing:Optimizing the thermal,visual,and energy performance

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Building simulation 2024年第6期17卷 857-875页

作者： Tarlan Abazari andréPotvin Louis Gosselin Claude MH Demers GRAP(Groupe de recherche en ambiance physiques) School of ArchitectureLaval UniversityQuébecCanada Department of Mechanical Engineering Faculty of Science and EngineeringLaval UniversityQuébecCanada

Connecting occupants to the outdoor environment and incorporating biophilic design principles are challenging in extreme Arctic climatic *** Arctic housing models do not provide efficient thermal and daylight transitions which are essential for the well-being and cultural needs of their *** address these challenges,this research develops free-running biophilic intermediate spaces,integrated into an existing Arctic housing *** simulation methods are employed to optimize the primary and secondary architectural design variables for 26 case studies of intermediate *** variables include volume,transparency ratio,and *** variables include materials and physical ***,Daylight Factor/Autonomy,and Energy Use are evaluated as performance *** reveal that free-running intermediate spaces with 6 meters depth and a transparency ratio above 50%provide efficient indoor–outdoor transitions regarding thermal,visual,and energy *** architectural configurations contribute to an approximately 5%reduction in energy consumption within the housing unit compared to the *** side windows prevents the risk of overheating during the summer by reducing the average indoor temperature of intermediate spaces by 7°C but increases the overall energy *** a potential alternative to double-glazing,polycarbonate sheets enable efficient thermal performance by increasing the average indoor temperature of intermediate spaces by approximately 15°C during the cold Arctic *** polycarbonate sheets results in a 16.6%reduction in energy consumption compared to using double-glazing material in intermediate space,and a 26%reduction from the *** outcomes contribute to efficient indoor–outdoor connections and energy efficiency in Arctic housing.

关键词： Arctic housing intermediate spaces biophilic design positive thermal transitions daylight availability energy efficiency

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自推进胶囊在小肠中移动时的优化控制

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机械工程学报 2024年

作者：廖茂林李智朱佳鹏王泽旭 JOsEPHPáez chávez 北京科技大学机械工程学院北京科技大学井下智能控制研究院德累斯顿工业大学动力学研究中心

在消化道检测领域，传统的管线式内镜常给患者带来极大的心理负担与生理不适，胶囊内镜则因驱动方式和控制复杂等原因而难以对小肠部位开展全面而高效的检测。为此，考虑以双边约束的激振胶囊为研究对象，根据小肠结构的变化分别建立了... 详细信息

在消化道检测领域，传统的管线式内镜常给患者带来极大的心理负担与生理不适，胶囊内镜则因驱动方式和控制复杂等原因而难以对小肠部位开展全面而高效的检测。为此，考虑以双边约束的激振胶囊为研究对象，根据小肠结构的变化分别建立了扩张段和狭窄段的小肠-胶囊耦合动力学模型，并以小肠多变的摩擦环境以及对胶囊的包裹程度不同作为不稳定因素，分析了自推进胶囊的动力学行为规律。基于此，同时以胶囊的移动速度、单位能耗和对小肠壁冲击力作为优化目标，采用(six-sigma+NsGA-II+Monte-Carlo)组合优化算法获取胶囊可控移动对应的参数组合区间。最终，结合ADAMs动力学仿真与实验测试验证了当采用优化后的参数组合控制自推进胶囊时，可使其实现低能耗低冲击的定速定向移动。

关键词：小肠胶囊非光滑多目标优化运动控制

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Geochemistry and mineral chemistry of the armoor granitoids,eastern dharwar craton: implications for the redox conditions and tectono-magmatic environment

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Acta Geochimica 2024年第1期43卷 110-133页

作者： A.Ajay Kumar ch.Ashok Department of Geology Osmania UniversityHyderabad 500007India CsIR-National Geophysical Research Institute UppalHyderabad 500007India

The mineralogical and geochemical characteristics of the K-rich granites from the Armoor granitic rocks in the northeastern portion of the Eastern Dharwar Craton(EDC) are *** order to understand its physicochemical conditions,the petrogenesis of the granitoid was explained from biotite chemistry and geochemical *** of mineral chemistry expose that compositionally,K-feldspar and plagioclase in Armoor granite rocks range from An0,Ab_(3-5.9),Or_(94-96.9) and An_(5-29,-Ab71.9-94.9),Or_(0-1.5),*** mineral chemistry of biotite crystals exhibits composition that varies from primary to re-equilibrated primary *** biotites from the Armoor granites generally exhibit an I-type trend,with calc-alkaline parental magma in a subduction *** chemistry of granites displays magnetite(oxidized)series nature,which has oxygen fugacity(fO_(2))=-15.1 to-16.7(log_(10) bar),under high oxidizing *** and pressure estimates for the crystallization of Armoor granites based on biotite composition are T=612-716 ℃ and 1.0-0.4 kbar,***,these rocks are metaluminous to slightly peraluminous and magnesian,with calc-alkaline potassiumrich *** the chondrite normalized REE diagram,the granites have positive europium anomalies;rich sr/Y,(Dy/Yb)_(N) ratios and reduced Mg#,Rb/sr,Rb,sr indicate that the melting of earlier rocks,crystal accumulation and residual garnet source formed at high *** examined granites show that they are produced from the melting of crustal ***,the extensive analyses of the described Armoor granite suggest that they were produced by crust sources and developed under oxidizing conditions in subduction setting.

关键词： Armoor granites Oxygen fugacity Crystal accumulation Remelting subduction

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A multi-platform analysis of human gingival crevicular fluid reveals ferroptosis as a relevant regulated cell death mechanism during the clinical progression of periodontitis

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International Journal of Oral science 2024年第2期16卷 265-279页

作者： Alfredo Torres M.Angélica Michea Ákos Végvári marion Arce Valentina Pérez Marcela Alcota Alicia Morales Rolando Vernal Mauricio Budini Roman A.Zubarev Fermín E.gonzález Laboratory of Experimental Immunology&Cancer Faculty of DentistryUniversity of ChileSantiagoChile Department of Conservative Dentistry Faculty of DentistryUniversity of ChileSantiagoChile Division of chemistry I Department of Medical Biochemistry and BiophysicsKarolinska InstitutetStockholmSweden Periodontal Biology Laboratory Faculty of DentistryUniversidad de ChileSantiagoChile Laboratory of Cellular and Molecular Pathology Institute for Research in Dental SciencesFaculty of DentistryUniversity of ChileSantiagoChile

Ferroptosis is implicated in the pathogenesis of numerous chronic-inflammatory diseases,yet its association with progressive periodontitis remains *** investigate the involvement and significance of ferroptosis in periodontitis progression,we assessed sixteen periodontitis-diagnosed *** progression was clinically monitored over twelve weeks via weekly clinical evaluations and gingival crevicular fluid(GCF)collection was performed for further *** metrics,proteomic data,in silico methods,and bioinformatics tools were combined to identify protein profiles linked to periodontitis progression and to explore their potential connection with *** western blot analyses validated key ***,a single-cell RNA sequencing(scRNA-seq)dataset(GsE164241)for gingival tissues was analyzed to elucidate cellular dynamics during periodontitis *** progression was identified as occurring at a faster rate than traditionally *** samples from progressing and non-progressing periodontal sites showed quantitative and qualitatively distinct proteomic *** addition,specific biological processes and molecular functions during progressive periodontitis were revealed and a set of hub proteins,including sNCA,CA1,HBB,sLC4A1,and ANK1 was strongly associated with the clinical progression status of ***,we found specific proteins-drivers or suppressors-associated with ferroptosis(sNCA,FTH1,HsPB1,CD44,and GCLC),revealing the co-occurrence of this specific type of regulated cell death during the clinical progression of ***,the integration of quantitative proteomic data with scRNA-seq analysis suggested the susceptibility of fibroblasts to *** analyses reveal proteins and processes linked to ferroptosis for the first time in periodontal patients,which offer new insights into the molecular mechanisms of progressive periodontal *** findings may le

关键词： finding progression faster

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Effect of thermo-mechanical conditions during constrained friction processing on the particle refinement of AM50 Mg-alloy phases

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Journal of Magnesium and Alloys 2024年第6期12卷 2298-2311页

作者： Camila Caroline de Castro andréMartins Neves Benjamin Klusemann Helmholtz-Zentrum Hereon Institute of Material and Process DesignSolid-State Materials Processing21502 GeesthachtGermany Helmholtz-Zentrum Hereon Institute of Hydrogen TechnologySystem Design for Mobility21502 GeesthachtGermany Helmut schmidt University/University of the German Federal Armed Forces Hamburg Department of Mechanical and Civil Engineering22043 HamburgGermany Leuphana University Lüneburg Institute for Production Technology and Systems21335 LüneburgGermany

Constrained Friction Processing(CFP)is a novel solid-state processing technique suitable for lightweight materials,such Mg-and *** technique enables grain size refinement to fine or even ultrafine *** this study,the effect of CFP on the microstructural refinement of AM50 rods is investigated in terms of particle size and morphology of the eutectic and secondary phases originally present in the base material,in particular the eutecticβ-Mg_(17)Al_(12)and Al-Mn *** that purpose,as-cast and solution heat-treated base material and processed samples were *** Al8Mn5 intermetallic phase was identified as the main secondary phase present in all samples before and after the processing.A notorious refinement of these particles was observed,starting from particles with an average equivalent length of a few micrometers to around 560 nm after the *** refinement of the secondary phase refinement is attributed to a mechanism analogous to the attrition comminution,where the combination of temperature increase and shearing of the material enables the continuous breaking of the brittle intermetallic particles into smaller *** for the eutectic phase,the results indicate the presence of the partially divorcedβ-Mg_(17)Al_(12)particles exclusively in the as-cast base material,indicating that no further phase transformations regarding the eutectic phase,such as dynamic precipitation,occurred after the *** the case of the processed as-cast material analyzed after the CFP,the thermal energy generated during the processing led to temperature values above the solvus limit of the eutectic phase,which associated with the mechanical breakage of the particles,enabled the complete dissolution of this ***,CFP was successfully demonstrated to promote an extensive microstructure refinement in multiple aspects,in terms of grain sizes of theα-Mg phase and presence and morphology of the Al-Mn and eutecticβ-Mg_(17)Al_(12).

关键词： Constrained friction processing AM50 Refill friction stir spot welding Extrusion β-Mg_(17)Al_(12) Al-Mn phases

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Pollen analysis reveals the effects of uncovered interactions,pollen-carrying structures,and pollinator sex on the structure of wild bee-plant networks

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Insect science 2024年第3期31卷 971-988页

作者： Clément Tourbez Carmelo Gómez-Martínez MiguelÁngel gonzalez-Estévez Amparo Lazaro Mediterranean Institute for Advanced studies(UIB-CsIC) Global Change Research GroupEsporlesBalearic IslandsSpain Department of Biology Ecology AreaUniversity of the Balearic/slandsPalmaSpain

Pollination networks are increasingly used to model the complexity of interactions between pollinators and flowering plants in *** methods exist to sample these interactions,with direct observations of plant-pollinator contacts in the field being by far the most *** the identification of pollen carried by pollinators allows uncovering interactions and increasing sample sizes,the methods used to build pollen-transport networks are variable and their effect on network structure remains *** understand how interaction sampling influences the structure of networks,we analyzed the pollen found on wild bees from eight communities across Mallorca Island and investigated the differences in pollen loads between bee body parts(scopa ***)and *** then assessed how these differences,as well as the uncovered interactions not detected in the field,influenced the structure of wild bee-plant *** identified a higher quantity and diversity of pollen in the scopa than in the rest of the female body,but these differences did not lead to differences in structure between plant-pollination(excluding scopa pollen)and bee-feeding interaction(including scopa pollen)***,networks built with pollen data were richer in plant species and interactions and showed lower modularity and specialization(H2'),and higher nestedness than visitation networks based on field *** interactions with plants were stronger compared to those of males,although not ***,females were more generalist(low d')and tended to be more central in interaction networks,indicating their more key role structuring pollination networks in comparison to *** study highlights the importance of palynological data to increase the resolution of networks,as well as to understand important ecological questions such as the differences between plant-pollination and bee-feeding interaction networks,and the role of sexes in pollination.

关键词： palynology pollen-transport networks pollination role of bee sexes sampling methodology visitation networks

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