检索结果-南通市图书馆

Self-assembly of highly ordered DNA origami lattices at solid-liquid interfaces by controlling cation binding and exchange

引用

Nano Research 2020年第11期13卷 3142-3150页

作者： Yang Xin Salvador Martinez Rivadeneira Guido Grundmeier mario castro Adrian Keller Technical and Macromolecular Chemistry Paderborn UniversityPaderborn33098Germany Grupo Interdisciplinar de Sistemas Complejos and Instituto de Investigación Tecnológica Universidad Pontificia Comillas de MadridMadrid28015Spain

The surface-assisted hierarchical self-assembly of DNA origami lattices represents a versatile and straightforward method for the organization of functional nanoscale objects such as proteins and ***,we demonstrate that controlling the binding and exchange of different monovalent and divalent cation species at the DNA-mica interface enables the self-assembly of highly ordered DNA origami lattices on mica *** development of lattice quality and order is quantified by a detailed topological analysis of high-speed atomic force microscopy(HS-AFM)*** find that lattice formation and quality strongly depend on the monovalent cation ***^(+)is more effective than Li^(+)and K^(+)in facilitating the assembly of high-quality DNA origami lattices,because it is replacing the divalent cations at their binding sites in the DNA backbone more *** regard to divalent cations,Ca^(2+)can be displaced more easily from the backbone phosphates than Mg^(2+)and is thus superior in guiding lattice *** independently adjusting incubation time,DNA origami concentration,and cation species,we thus obtain a highly ordered DNA origami lattice with an unprecedented normalized correlation length of *** the correlation length,we use computer vision algorithms to compute the time course of different topological observables that,overall,demonstrate that replacing MgCl_(2) by CaCl_(2) enables the synthesis of DNA origami lattices with drastically increased lattice order.

关键词： DNA origami self-assembly lattice formation high-speed atomic force microscopy topological analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The off-crust origin of granite batholiths

引用

Geoscience Frontiers 2014年第1期5卷 63-75页

作者： Antonio castro Unidad Asociada de Petrología Experimental CSIC-Universidad de Huelva.Campus El Carmen21071 Huelva Spain

Granitod batholiths of I-type features （mostly granodiorites and tonalites）, and particularly those forming the large plutonic associations of active continental margins and intracontinental collisional belts, represent the most outstanding magmatic episodes occurred in the continental crust. The origin of magmas, however, remains controversial. The application of principles from phase equilibria is crucial to understand the problem of granitoid magma generation. An adequate comparison between rock com- positions and experimental liquids has been addressed by using a projected compositional space in the plane F（Fe ＋ Mg）-Anorthite-Orthoclase. Many calc-alkaline granitoid trends can be considered cotectic liquids. Assimilation of country rocks and other not-cotectic processes are identified in the projected diagram. The identification of cotectic patterns in batholith implies high temperatures of magma segregation and fractionation （or partial melting） from an intermediate （andesitic） source. The com- parison of batholiths with lower crust granulites, in terms of major-element geochemistry, yields that both represent liquids and solid residues respectively from a common andesitic system. This is compatible with magmas being formed by melting, and eventual reaction with the peridotite mantle, of subducted mOlanges that are finally relaminated as magmas to the lower crust. Thus, the off-crust generation of granitoids batholiths constitutes a new paradigm in which important geological implica- tions can be satisfactorily explained. Geochemical features of Cordilleran-type batholiths are totally compatible with this new conception.

关键词： Batholith Granodiorite Andesite Relamination Granulite Lower crust

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unsuitable use of spin and pseudospin symmetries with a pseudoscalar Cornell potential

引用

Chinese Physics B 2014年第9期23卷 60-61页

作者： L.B.castro A.S.de castro Departamento de Física CFM Universidade Federal de Santa Catarina Departamento de Física Universidade Federal do Maranho Campus Universtitrio do Bacanga Departamento de Física e Química Campus de Guaratinguet Universidade Estadual Paulista

The concepts of spin and pseudospin symmetries has been used as mere rhetorics to decorate the pseudoscalar potential [Chin. Phys. B 22 090301 （2013）]. It is also pointed out that a more complete analysis of the bou... 详细信息

关键词： Dirac equation pseudoscalar Comell potential spin symmetry pseudospin symmetry

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Robotic-assisted placement of hepatic artery infusion pump for the treatment of colorectal liver metastases:Role of indocyanine green(with video)

引用

Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 387-391页

作者： mario Spaggiari Kiara A Tulla Gabriela Aguiluz Pierpaolo Di Cocco Lola castro Gil Enrico Benedetti Ivo G Tzvetanov Pier Cristoforo Giulianotti Division of Transplantation Department of SurgeryUniversity of Illinois at ChicagoChicagoILUSA Division of General Minimally Invasiveand Robotic SurgeryDepartment of SurgeryUniversity of Illinois at ChicagoChicagoILUSA

Surgical resection remains the only definitive treatment for colorectal liver metastasis(CRLM). However, only a minority of cases are deemed resectable at the time of diagnosis. Systemic chemotherapy along with hepatic artery infusion(HAI) is an effective and safe regional chemotherapy modality for the downstaging of patients with isolated unresectable CRLM [1].

关键词： chemotherapy liver artery treatment metastasis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The role of BRCA 1 and BRCA2 in prostate cancer

引用

Asian Journal of Andrology 2012年第3期14卷 409-414,I0006页

作者： Elena castro Rosalind Eeles Oncogenetics Team The Institute of Cancer Research Sutton SM2 5NG UK Academic Urology Unit The Royal Marsden NH Foundation Trust London SW3 6J J UK

One of the strongest risk factors for prostate cancer is a family history of the disease. Germline mutations in the breast cancer predisposition gene 2 （BRCA2） are the genetic events known to date that confer the highest risk of prostate cancer （8.6-fold in men ≤ 65 years）. Although the role of BRCA2 and BRCA1 in prostate tumorigenesis remains unrevealed, deleterious mutations in both genes have been associated with more aggressive disease and poor clinical outcomes. The increasing incidence of prostate cancer worldwide supports the need for new methods to predict outcome and identify patients with potentially lethal forms of the disease. As we present here, BRCA germline mutations, mainly in the BRCA2gene, are one of those predictive factors. We will also discuss the implications of these mutations in the management of prostate cancer and hypothesize on the potential for the development of strategies for sooradic cases with similar characteristics.

关键词： BRCA1 BRCA2 prostate cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recent progress on isospin breaking corrections and their impact on the muon g-2 value

引用

Chinese Physics C 2010年第6期34卷 712-717页

作者： Gabriel López castro Departamento de Física CinvestavApartado Postal 14-74007000 MxicoD.F Mxico

We describe some recent results on isospin breaking corrections which are of relevance for predictions of the leading order hadronic contribution to the muon anomalous magnetic moment aμ^*** when using τ lepton data. When these corrections are applied to the new combined data on the π^±π^0 spectral function, the prediction for aμ^*** based on τ lepton data gets closer to the one obtained using e^＋e^- data.

关键词： isospin breaking tau decays muon magnetic moment radiative corrections

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

引用

Chinese Annals of Mathematics,Series B 2009年第5期30卷 505-512页

作者： Angel castro Diego CóRDOBA Instituto de Ciencias Matemticas CSIC-UAM-UC3M-UCMConsejo Superior de Investigaciones Científicas

The authors construct self-similar solutions for an N-dimensional transport equation,where the velocity is given by the Riezs *** solutions imply nonuniqueness of weak *** addition,self-similar solution for a one-dime... 详细信息

关键词： Hilbert transform Riesz transform Transport equations Self-similar solutions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lagrangian Submanifolds Foliated by(n-1)-spheres in R^(2n)

引用

Acta Mathematica Sinica,English Series 2006年第4期22卷 1197-1214页

作者： Henri ANCIAUX Ildefonso castro Pascal ROMON PUC-RioDepartamento de Matemática Rua Marques de Sao Vicente225-GáveaRio de Janeiro-Brazil-CEP 22453-900 Departamento de Matemáticas Universidad de Jaén23071 JaénSpain Université de Marne-la-Vallée 5 bd DescartesChamps-sur-Marne77454 Marne-la- Vallée cedex 2France

We study Lagrangian submanifolds foliated by （n - 1）-spheres in R^2n for n ≥ 3. We give a general parametrization for such submanifolds, and refine that description when the submanifold is special Lagrangian, self-similar, Hamiltonian stationary or has mean curvature vector of constant length. In all these cases, the submanifold is centered, i.e. invariant under the action of SO（n）. It suffices then to solve a simple ODE in two variables to describe the geometry of the solutions.

关键词： Lagrangian submanifold special Lagrangian self-similar Hamiltonian stationary

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

alcohol drinking and mammary cancer: pathogenesis and potential dietary preventive alternatives

引用

World Journal of Clinical Oncology 2014年第4期5卷 713-729页

作者： Gerardo Daniel castro José A castro Centro de Investigaciones Toxicológicas CITEDEF B1603ALO Villa Martelli province of Buenos Aires Argentina Instituto de Investigación e Ingeniería Ambiental Universidad Nacional de General San Martín B1650ANQ San Martín province of Buenos Aires Argentina

Alcohol consumption is associated with an increased risk of breast cancer, increasing linearly even with a moderate consumption and irrespectively of the type of alcoholic beverage. It shows no dependency from other risk factors like menopausal status, oral contraceptives, hormone replacement therapy, or genetic history of breast cancer. The precise mechanism for the effect of drinking alcohol in mammary cancer promotion is still far from being established. Studies by our laboratory suggest that acetaldehyde produced in situ and accumulated in mammary tissue because of poor detoxicating mechanisms might play a role in mutational and promotional events. Additional studies indicated the production of reactive oxygen species accompanied of decreases in vitamin E and GSH contents and of glutathione transferase activity. The resulting oxidative stress might also play a relevant role in several stages of the carcinogenic process. There are reported in literature studies showing that plasmatic levels ofestrogens significantly increased after alcohol drinking and that the breast cancer risk is higher in receptor ERpositive individuals. Estrogens are known that they may produce breast cancer by actions on ER and also as chemical carcinogens, as a consequence of their oxidation leading to reactive metabolites. In this review we introduce our working hypothesis integrating the acetaldehyde and the oxidative stress effects with those involving increased estrogen levels. We also analyze potential preventive actions that might be accessible. There remains the fact that alcohol drinking is just one of the avoidable causes of breast cancer and that, at present, the suggested acceptable dose for prevention of this risk is of one drink per day.

关键词： Alcohol Ethanol Acetaldehyde Free radicals Mammary cancer Oxidative stress Estrogens Polyphenols

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

An overview on nucleation theories and models

引用

Journal of Rare Earths 2019年第10期37卷 1015-1022页

作者： Marcos Flavio de Campos Jose Adilson de castro Department of Mechanical Engineering Federal Fluminense University

Several different models for coercivity are discussed. There are two main situations: i) nanocrystalline magnets, with grain size bellow the single domain particle size, and ii) magnets with grain size above single domain particle size. The described theories and models are general, and can be applied in either NdFeB magnets, SmFeCoCuZr or strontium ferrite magnets. The spring effect observed in isotropic nanocrystalline magnets can be explained with the Stoner-Wohlfarth model. Modifications of the StonerWohlfarth model are necessary to take into account the effect of interaction between grains. When the grain size is above the single domain size, energy considerations show that nucleation should occur at the surface of grains. Nucleation is interpreted as a two-step process, where domain wall displacement occurs for grain size above single domain size, after a nucleus is first formed. The effect of grain size on the coercive field is discussed.

关键词： Coercivity Nucleation Grain size Spring effect Nd-Fe-B Permanent magnet

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：