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Global-in-time Uniform Convergence for Linear Hyperbolic-Parabolic Singular Perturbations

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Acta Mathematica Sinica,English Series 2006年第4期22卷 1161-1170页

作者： marina GHISI Massimo GOBBINO Universitàdegli Studi di Pisa Dipartimento di Matematicavia M.Buonarroti 256127 PISAItaly Universitàdegli Studi di Pisa Dipartimento di Matematica Applicata "Ulisse Dini"via Bonanno 25/B56126 PISAItaly

We consider the Cauchy problem εu^″ε ＋ δu′ε ＋ Auε = 0, uε（0） = uo, u′ε（0） = ul, where ε 〉 0, δ 〉 0, H is a Hilbert space, and A is a self-adjoint linear non-negative operator on H with dense domain D（A）. We study the convergence of （uε） to the solution of the limit problem ,δu＇＋ Au = 0, u（0） = u0. For initial data （u0, u1） ∈ D（A1/2）× H, we prove global-in-time convergence with respect to strong topologies. Moreover, we estimate the convergence rate in the case where （u0, u1）∈ D（A3/2） ∈ D（A1/2）, and we show that this regularity requirement is sharp for our estimates. We give also an upper bound for ｜u′ε（t）｜ which does not depend on ε.

关键词： Parabolic equations Damped hyperbolic equations Singular perturbations

The SO(3,1)-Gauge Invariant Approach to Fermions on Rindler Spacetime

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Chinese Physics Letters 2016年第2期33卷 1-4页

作者： Ciprian Dariescu marina-Aura Dariescu Faculty of Physics Alexandru Ioan Cuza University of Iasi

We try to explicitly derive the Lorentz-gauge covariant Dirac equation, in terms of pseudo-orthonormal bases, on Rindler spacetime and to work out, with all the necessary coefficients, the respective closed-form solut... 详细信息

关键词： in with as of form Gauge Invariant Approach to Fermions on Rindler Spacetime The SO on

Preoperative albumin-bilirubin score is a prognostic factor for gastric cancer patients after curative gastrectomy

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1125-1137页

作者： Daniel Jose Szor marina Alessandra Pereira Marcus Fernando Kodama Pertille Ramos Francisco Tustumi Andre Roncon Dias Bruno Zilberstein Ulysses ribeiro Jr Department of Gastroenterology Instituto do CancerHospital das Clinicas HCFMUSPFaculdade de MedicinaUniversidade de Sao PauloSao Paulo 01246000Brazil

BACKGROUND Albumin-bilirubin(ALBI)score is an indicator of liver dysfunction and is useful for predicting prognosis of hepatocellular ***,this liver function index has been used to predict prognosis in other ***,the significance of ALBI score in gastric cancer(GC)after radical resection has not been *** To evaluate the prognostic value of the preoperative ALBI status in patients with GC who received curative *** Patients with GC who underwent curative intended gastrectomy were retrospectively evaluated from our prospective *** score was calculated as follows:(log10 bilirubin×0.660)+(albumin×-0.085).The receiver operating characteristic curve with area under the curve(AUC)was plotted to evaluate the ability of ALBI score in predicting recurrence or *** optimal cutoff value was determined by maximizing Youden’s index,and patients were divided into low and high-ALBI *** Kaplan-Meier curve was used to analyze the survival,and the log-rank test was used for comparison between *** A total of 361 patients(235 males)were *** median ALBI value for the entire cohort was-2.89(IQR-3.13;-2.59).The AUC for ALBI score was 0.617(95%CI:0.556-0.673,P<0.001),and the cutoff value ***,211(58.4%)patients were classified as low-ALBI group and 150(41.6%)as high-ALBI *** age(P=0.005),lower hemoglobin level(P<0.001),American Society of Anesthesiologists classification III/IV(P=0.001),and D1 lymphadenectomy P=0.003)were more frequent in the high-ALBI *** was no difference between both groups in terms of Lauren histological type,depth of tumor invasion(pT),presence of lymph node metastasis(pN),and pathologic(pTNM)*** postoperative complication,and mortality at 30 and 90 days were higher in the high-ALBI *** the survival analysis,the high-ALBI group had worse disease-free survival(DFS)and overall survival(OS)compared to those with low-ALBI(P<0.001).

关键词： Stomach neoplasms Adenocarcinoma Albumin-bilirubin Biomarker Prognosis Survival

Chiral Fermion Conductivity in Graphene-Like Samples Subjected to Orthogonal Fields

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Chinese Physics Letters 2012年第1期29卷 20-23页

作者： Ciprian Dariescu marina-Aura Dariescu Faculty of Physics Alexandru Ioan Cuza University of IaşiBd.Carol I No.11700506 IaşiRomania

Starting with the U(1)-gauge covariant four-dimensional Dirac equation,we derive the analytic solutions describing the chiral massless fermions evolving in static orthogonal magnetic and electric *** in cylindric coordinates,we compute the electric current density essential component and the off-diagonal *** summing up the conductivities of the two distinct species of electrons connected to the orientation of spin,the well-known 4n-quantization law is restored.

关键词： Fermi diagonal Conductivity

Unsteady Inflow Effects on the Wake Shed from a High-Lift LPT Blade Subjected to Boundary Layer Laminar Separation

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Journal of Thermal Science 2012年第2期21卷 97-108页

作者： Francesca Satta marina Ubaldi Pietro Zunino Università degli Studi di Genova

An experimental investigation on the near and far wake of a cascade of high-lift low-pressure turbine blades subjected to boundary layer separation over the suction side surface has been carried out, under steady and unsteady inflows. Two Reynolds number conditions, representative of take-off/landing and cruise operating conditions of the real engine, have been tested. The effect of upstream wake-boundary layer interaction on the wake shed from the profile has been investigated in a three-blade large-scale linear turbine cascade. The comparison between the wakes shed under steady and unsteady inflows has been performed through the analysis of mean velocity and Reynolds stress components measured at midspan of the central blade by means of a two-component crossed miniature hot-wire probe. The wake development has been analyzed in the region between 2% and 100% of the blade chord from the central blade trailing edge, aligned with the blade exit direction. Wake integral parameters, half-width and maximum velocity defects have been evaluated from the mean velocity distributions to quantify the modifications induced on the vane wake by the upstream wake. Moreover the thicknesses of the two wake shear layers have been considered separately in order to identify the effects of Reynolds number and incoming flow on the wake shape. The self-preserving state of the wake has been looked at, taking into account the different thicknesses of the two shear layers. The evaluation of the power density spectra of the velocity fluctuations allowed the study of the wake unsteady behavior, and the detection of the effects induced by the different operating conditions on the trailing edge vortex shedding.

关键词： Wake-wake unsteady interaction high-lift blade profiles low-pressure turbine blade wake.

Gastric partitioning for the treatment of malignant gastric outlet obstruction

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World Journal of Gastrointestinal Oncology 2019年第12期11卷 1161-1171页

作者： Marcus Fernando Kodama Pertille Ramos Leandro Cardoso Barchi Rodrigo Jose de Oliveira marina Alessandra Pereira Donato Roberto Mucerino Ulysses ribeiro Jr Bruno Zilberstein Ivan Cecconello Department of Gastroenterology Hospital das Clinicas HCFMUSPFaculdade de MedicinaUniversidade de Sao Paulo

BACKGROUND Gastric outlet obstruction(GOO)is one of the main complications in stage IV gastric cancer *** condition is usually managed by gastrojejunostomy(GJ).However,gastric partitioning(GP)has been described as an alternative to overcoming possible drawbacks of GJ,such as delayed gastric emptying and tumor *** To compare the outcomes of patients who underwent GP and GJ for malignant *** We retrospectively analyzed 60 patients who underwent palliative gastric bypass for unresectable distal gastric cancer with GOO from 2009 to *** clinicopathological characteristics including age,nutritional status,body mass index,and performance status were *** symptoms were graded according to GOO score(GOOS).Surgical outcomes evaluated included duration of the procedure,surgical complications,mortality,and length of hospital *** of oral diet after the procedure,weight gain,and overall survival were the long-term outcomes *** GP was performed in 30 patients and conventional GJ in the other 30 *** mean follow-up was 9.2 ***-nine(81.6%)patients died during that *** variables were similar between groups,with the exception of worse performance status in GP *** mean operative time was higher in the GP group(161.2 vs 85.2 min,P<0.001).There were no differences in postoperative complications and surgical mortality between *** median overall survival was 7 and 8.4 mo for the GP and GJ groups,respectively(P=0.610).The oral acceptance of soft solids(GOOS 2)and low residue or full diet(GOOS 3)were reached by 28(93.3%)GP patients and 22(75.9%)GJ patients(P=0.080).Multivariate analysis demonstrated that GOOS 2 and GOOS 3 were the main prognostic factors for survival(hazard ratio:8.90,95%confidence interval:3.38-23.43,P<0.001).CONCLUSION GP is a safe and effective procedure to treat *** to GJ,it provides similar surgical outcomes with a trend to better solid diet accep

关键词： Stomach neoplasms Gastric outlet obstruction Palliative surgery Gastrojejunostomy Gastric cancer

跨媒介表征:论亚历山大·格林小说中的文学图像

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广东开放大学学报 2024年第2期33卷 64-69页

作者：布哈罗娃·玛丽娜天津师范大学天津300382

俄国白银时代重要作家亚历山大·格林在其小说中擅用绘画元素呈现浪漫主义的艺术审美,绘画成为小说文本的媒介呈现。拥有良好艺术功底的格林惯常以绘画作为介质实现小说文本的艺术追求,通过“文学图像”的活现,格林小说中语像和图像“... 详细信息

俄国白银时代重要作家亚历山大·格林在其小说中擅用绘画元素呈现浪漫主义的艺术审美,绘画成为小说文本的媒介呈现。拥有良好艺术功底的格林惯常以绘画作为介质实现小说文本的艺术追求,通过“文学图像”的活现,格林小说中语像和图像“以图言说”“语图互仿”与“语图互文”的动态关系呈现,使得小说人物塑造得更为丰满,推动了小说情节叙事,打通了文本空间与现实空间的桎梏,促使人们通过观赏感受到艺术再现以及艺术与现实之间的融合。亚历山大·格林以绘画植入小说文本,实现了跨媒介、跨文本的融合,从而形成了其创作的独特性。

关键词：亚历山大·格林文学图像绘画框架艺术再现

Autophagy inhibition: a new therapeutic target in spinal muscular atrophy

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Neural Regeneration Research 2018年第5期13卷 813-814页

作者： Antonio Piras marina Boido Neuroscience Institute Cavalieri Ottolenghi (NICO) Dept. Neuroscience University of Torino

Spinal muscular atrophy（SMA）is a hereditary pediatric motor neuron（MN）disease：survival motor neuron 1（SMN1）gene mutation determines MN degeneration and,consequently,muscle atrophy,breathing and swallowing difficulties,and,in the most severe cases,premature death.A second unaffected gene（SMN2）is present,but it can only produce a limited amount of functional protein,modulating the disease severity and progression.

关键词： Figure SMN a new therapeutic target in spinal muscular atrophy SMA

5-ASA in ulcerative colitis:Improving treatment compliance

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World Journal of Gastroenterology 2009年第35期15卷 4353-4355页

作者： Cosimo Prantera marina Rizzi Department of Gastroenterology Azienda Ospedaliera San Camillo-ForlaniniCirconvallazione Gianicolense 8700152 RomeItaly Department of Gastroenterology University Campus Bio Medicovia Alvaro del Portillo 20000128 Rome Italy

5-aminosalicylic acid(5-ASA)compounds are a highly effective treatment for ulcerative colitis(UC).While UC patient compliance in clinical studies is over 90%, only 40%of patients in every day life take their prescribed *** to medication has been emphasized recently by a Cochrane meta-analysis that has suggested that future trials of 5-ASA in UC should look at patient compliance rather than drug efficacy. Better compliance can be obtained by reducing the number of tablets and times of *** that the 5-ASA formulations have different delivery systems that split the active moiety in various regions of the intestine,it is particularly important that an adequate dose of the drug arrives at the inflamed part of the colon.5-ASA Multi matrix(MMx)is a novel,high strength(1.2 g),oral formulation designed for oncedaily *** releases the active moiety throughout the *** studies with this compound have shown that it is as effective as 5-ASA enema in the treatment of mild-to-moderate,left-sided UC,and is comparable to a pH-dependent,delayed release 5-ASA (Asacol ),even if given once ***,the effectiveness in the acute phase of UC has been confirmed also in *** conclusion,at present,5-ASA MMx seems theoretically the best agent for maintaining patient compliance,and consequently,treatment effectiveness.

关键词： 5-aminosalicylic acid Mesalamine Multi matrix Patient compliance Ulcerative colitis