检索结果-南通市图书馆

化工矿山译丛 1992年第2期 49-51页

作者： marin.,d 王尔哲

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

用于球磨机控制的新型传感器系统

大冶科技 1992年第3期 21-24页

作者： marin.,d 朝明修

Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & diseases 2024年第3期11卷 311-323页

作者： david Sanchez-marin.Macrina Beatriz Silva-Cazares Fany Iris Porras-Reyes Rebeca Garcia-Roman Alma d.Campos-Parra Posgrado en Ciencias Biologicas Facultad de MedicinaUniversidad Nacional Autonoma de MexicoCiudad de MexicoC.P.04360Mexico Unidad Academica Multidisciplinaria Region Altiplano Universidad Autonoma de San Luis Potost(UASLP)Carretera a Cedral Km 5+600Ejido San Jose de la TrojesMatehualaSan Luis PotosiC.P.78760Mexico Servicio de Anatomia Patologica Instituto Nacional de Cancerologia(INCan)Nino JesuisTlalpanCiudaddeMexicoC.P.14080Mexico Instituto de Salud Publica Universidad Veracruzana(UV)Av.Dr LuisDr.Castelazo Ayala s/nCol.Industrial AnimasXalapaVeracruzC.P.91190Mexico

Long non-coding RNAs(lncRNAs)are non-coding RNAs longer than 200 nucleotides with dynamic regulatory *** interact with a wide range of molecules such as dNA,RNA,and proteins to modulate diverse cellular functions through several mechanisms and,if deregulated,they can lead to cancer development and ***,it has been described that IncRNAs are susceptible to form gene fusions with mRNAs or other IncRNAs,breaking the paradigm of gene fusions consisting mainly of protein-coding ***,their biological significance in the tumor phenotype is still ***,their recent identification opens a new line of research to study their biological role in tumor-igenesis,and their potential as biomarkers with clinical relevance or as therapeutic *** present study aimed to review the IncRNA fusions identified so far and to know which of them have been associated with a potential *** address the current challenges to deepen their study as well as the reasons why they represent a future therapeutic window incancer.

关键词： Cancer Genefusions IncRNAs ncRNAs Therapy

Growth differentiation factor-15 serum concentrations reflect disease severity and anemia in patients with inflammatory bowel disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第13期30卷 1899-1910页

作者： Ante Tonkic Marko Kumric Ivna Akrapovic Olic doris Rusic Piero marin.Zivkovic daniela Supe domic Zeljko Sundov Ivan Males Josko Bozic Biology of Neoplasms University of Split School of MedicineSplit 21000Croatia department of Pathophysiology University of Split School of MedicineSplit 21000Croatia department of Gastroenterology University Hospital of SplitSplit 21000Croatia department of Pharmacy University of Split School of MedicineSplit 21000Croatia department of Medical Laboratory diagnostics University Hospital of SplitSplit 21000Croatia department of Health Studies University of SplitSplit 21000Croatia department of Internal Medicine University of Split School of MedicineSplit 21000Croatia department of Surgery University Hospital of SplitSplit 21000Croatia

BACKGROUNd Population of patients with inflammatory bowel disease(IBd)is burdened by various extraintestinal manifestations which substantially contribute to greater morbidity and ***-differentiation factor-15(GdF-15)is often overexpressed under stress conditions,such as inflammation,malignancies,heart failure,myocardial ischemia,and many *** To explore the association between GdF-15 and IBd as serum concentrations of GdF-15 were shown to be an independent predictor of poor outcomes in multiple *** additional aim was to determine possible associations between GdF-15 and multiple clinical,anthropometric and laboratory parameters in patients with *** This cross-sectional study included 90 adult patients diagnosed with IBd,encompassing both Crohn’s disease(Cd)and ulcerative colitis(UC),and 67 healthy age-and sex-matched *** patients underwent an extensive workup,including colonoscopy with subsequent histopathological *** activity was assessed by two independent gastroenterology consultants specialized in IBd,employing well-established clinical and endoscopic scoring ***-15 serum concentrations were determined following an overnight fasting,using electrochemiluminescence *** In patients with IBd,serum GdF-15 concentrations were significantly higher in comparison to the healthy controls[800(512-1154)pg/mL vs 412(407-424)pg/mL,Pdifference in GdF-15 was found between patients with Cd and UC[807(554-1451)pg/mL vs 790(509-956)pg/mL,P=0.324].Moreover,multiple linear regression analysis showed that GdF-15 levels predict Cd and UC severity independent of age,sex,and C-reactive protein levels(P=0.016 and P=0.049,respectively).Finally,an association between GdF-15 and indices of anemia was ***,negative correlations were found between GdF-15 and serum iron levels(r=-0.248,P=0.021),as well as GdF-15 and hemoglobin(r=-0.351,P=0.021).Accordingly,in comparison to I

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Growth-differentiation factor-15 Anemia Extraintestinal manifestations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

时间隔离——一种新的控制交尾模式

中国蜂业 2024年第5期75卷 22-23页

作者： Aleksandar Uzunov marin.Kovacic 陈超单金琼中国农业科学院蜜蜂研究所资源昆虫高效养殖与利用全国重点实验室北京100193 北马其顿圣基里尔·麦托迪大学农业科学与食品学院斯科普里1000 克罗地亚奥西耶克大学农业生物技术科学学院奥西耶克31000

控制交尾是蜜蜂育种项目中遗传改良和保护的关键因素。在上一期文章中,我们讨论了控制交尾的四种可选的模式及其相关性,即地理隔离、生物隔离、人工授精和时间隔离。实际上,最后一种模式在近几十年刚刚发展起来,可以作为传统模式的一种... 详细信息

控制交尾是蜜蜂育种项目中遗传改良和保护的关键因素。在上一期文章中,我们讨论了控制交尾的四种可选的模式及其相关性,即地理隔离、生物隔离、人工授精和时间隔离。实际上,最后一种模式在近几十年刚刚发展起来,可以作为传统模式的一种替代模式。在本文中,我们更加详细的介绍时间隔离的概念及其变体,这种模式吸引了蜜蜂育种人员和育王人员的高度关注。

关键词：地理隔离时间隔离育王遗传改良替代模式蜜蜂育种交尾人工授精

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

时间隔离——控制交尾的替代方案及新发展

中国蜂业 2024年第6期75卷 26-27页

作者： Aleksandar Uzunov marin.Kovacic 段宇杰陈超中国农业科学院蜜蜂研究所资源昆虫高效养殖与利用全国重点实验室北京100193 北马其顿圣基里尔·麦托迪大学农业科学与食品学院斯科普里1000 克罗地亚奥西耶克大学农业生物技术科学学院奥西耶克31000

时间隔离的第二种方法被称为“迷宫”,这个装置可以将蜂王限制在交尾箱中或将其释放。该方法不需要黑暗和寒冷的环境,并且配备该装置的交尾箱可以始终放置在室外。这让蜂农的工作变得更简单,而且由于无需制冷设备,该装置的成本也会较低... 详细信息

时间隔离的第二种方法被称为“迷宫”,这个装置可以将蜂王限制在交尾箱中或将其释放。该方法不需要黑暗和寒冷的环境,并且配备该装置的交尾箱可以始终放置在室外。这让蜂农的工作变得更简单,而且由于无需制冷设备,该装置的成本也会较低。然而,交尾箱需要安装迷宫进行改装。下面简要介绍一下迷宫这种装置以及操作步骤。

关键词：交尾箱时间隔离制冷设备替代方案迷宫操作步骤蜂王蜂农

Non-Abelian generalizations of the Hofstadter model:spin-orbit-coupled butterfly pairs

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2020年第1期9卷 302-314页

作者： Yi Yang Bo Zhen John d.Joannopoulos marin.Soljacic department of Physics and Research Laboratory of Electronics Massachusetts Institute of TechnologyCambridgeMA 02139USA department of Physics and Astronomy University of PennsylvaniaPhiladelphiaPA 19104USA

The Hofstadter model,well known for its fractal butterfly spectrum,describes two-dimensional electrons under a perpendicular magnetic field,which gives rise to the integer quantum Hall *** by the real-space building blocks of non-Abelian gauge fields from a recent experiment,we introduce and theoretically study two non-Abelian generalizations of the Hofstadter *** model describes two pairs of Hofstadter butterflies that are spin–orbit *** contrast to the original Hofstadter model that can be equivalently studied in the Landau and symmetric gauges,the corresponding non-Abelian generalizations exhibit distinct spectra due to the non-commutativity of the gauge *** derive the genuine(necessary and sufficient)non-Abelian condition for the two models from the commutativity of their arbitrary loop *** zero energy,the models are gapless and host Weyl and dirac points protected by internal and crystalline ***(8-fold),triple(12-fold),and quadrupole(16-fold)dirac points also emerge,especially under equal hopping phases of the non-Abelian *** other fillings,the gapped phases of the models give rise to topological *** conclude by discussing possible schemes for experimental realization of the models on photonic platforms.

关键词： generalization gauge Abelian

The Plane WavesMethod for Numerical Boundary Identification

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Applied Mathematics and Mechanics 2017年第6期9卷 1312-1329页

作者： A.Karageorghis d.Lesnic L.marin department ofMathematics and Statistics University of CyprusP.O.Box 205371678 NicosiaCyprus department of AppliedMathematics University of LeedsLeeds LS29JTUK department of Mathematics Faculty of Mathematics and Computer ScienceUniversity of Bucharest14 Academiei010014 Bucharestand Institute of Mathematical Statistics and Applied MathematicsRomanian Academy13 Calea 13 Septembrie050711 BucharestRomania

We study the numerical identification of an unknown portion of the boundary on which either the dirichlet or the Neumann condition is provided from the knowledge of Cauchy data on the remaining,accessible and known part of the boundary of a two-dimensional domain,for problems governed by Helmholtz-type *** inverse geometric problem is solved using the plane wavesmethod(PWM)in conjunction with the Tikhonov *** value for the regularization parameter is chosen according toHansen’s L-curve *** stability,convergence,accuracy and efficiency of the proposedmethod are investigated by considering several examples.

关键词： Plane waves method collocation inverse problem regularization

New opportunities for light-based tumor treatment with an“iron fist”

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2022年第4期11卷 457-459页

作者： Riccardo marin.Erving Ximendes daniel Jaque Nanomaterials for Bioimaging Group(NanoBIG) Departamento de Ffsica de MaterialesFacultad de CienciasUniversidad Aut6noma de MadridMadrid 28030Spain

The efficacy of photodynamic treatments of tumors can be significantly improved by using a new generation of nanoparticles that take advantage of the unique properties of the tumor microenvironment.

关键词： protective light treatment

A Simple and Efficient Structural Topology Optimization Implementation Using Open-Source Software for All Steps of the Algorithm:Modeling, Sensitivity Analysis and Optimization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2023年第8期136卷 1371-1397页

作者： Rafael marin.Ferro Renato Pavanello Coordination of Mechanical Engineering Federal Institute of Science and Technology of ES-IFESAracruz-ES29192-733Brazil department of Computational Mechanics Faculty of Mechanical EngineeringUnicampCampinas-SP13083-860Brazil

This work analyzes the implementation of a continuous method of structural topology optimization(STO)using open-source software for all stages of the topology optimization problem:modeling,sensitivity analysis and *** implementation involves three main components:numerical analysis using the Finite Element Method(FEM),sensitivity analysis using an Adjoint method and an optimization *** order to allow the automated numerical solution of Partial differential Equations(PdEs)and perform a sensitivity analysis,FEniCS and dolfin Adjoint software are used as tools,which are open-source *** the optimization process,Ipopt(Interior Point OPTimizer)is used,which is a software package for nonlinear optimization scale designed to find(local)solutions of mathematical optimization *** topological optimization method used is based on the SIMP-Solid IsotropicMaterial with Penalization *** considered problem is the minimization of compliance/maximization of stiffness,considering the examples of recurrent structures in the literature in 2d and 3d.A density filtering algorithm based on Helmholtz formulation is *** complete code involves 51 lines of programming and is presented and commented in detail in this article.

关键词： Structural topology optimization finite element method FEniCS dolfin Adjoint