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入院时血CGA浓度:早期预测ICU患者严重程度的生物学指标

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入院时血CGA浓度:早期预测ICU患者严重程度的生物学指标

中华医学会第五次全国重症医学大会

作者： Dan Zhang Thierry Lavigne Vincent Castelain Dominique Aunis marie-Helene Metz-Boutigue Francis Schneider Reanimation Medicale Hopital de HautepierreStrasbourgFrance INSERM U 575StrasbourgF-67000 France First Hospital Chongqing University of Medical Science Chongqing China

研究背景嗜铬粒蛋白A(CGA),是由肾上腺髓质产生的,与儿茶酚胺一起分泌入血的应激标志物,至今还未有CGA在危重病人的炎症反应中的研究。研究目的本研究旨在了解在系统性炎症反应(SIRS)的危重病人中,CGA的血浆浓度与炎症反应标志物以及患...

研究背景嗜铬粒蛋白A(CGA),是由肾上腺髓质产生的,与儿茶酚胺一起分泌入血的应激标志物,至今还未有CGA在危重病人的炎症反应中的研究。研究目的本研究旨在了解在系统性炎症反应(SIRS)的危重病人中,CGA的血浆浓度与炎症反应标志物以及患者预后的关系。研究目的检测53例病人入院时和14例健康对照组的血浆CGA浓度,前降钙素原,C反应蛋白等炎症反应指标。计算简明急性生理功能评分(SAPS),Logistic器官功能障碍系统等评分(LODS)。研究结果CGA的血浆浓度在SIRS患者中明显增高,其中间值为115μg/L(68.0-202.8),和健康对照组的相比有统计学差异(P<0.001)。在SIRS合并感染的病人,患者CGA浓度显著增高,中间值为138.5μg/L(65-222.3)(p<0.001)。CGA的浓度和炎症介质前

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带呼吸器娱乐潜水时死亡的病理及其机制——法医学观点

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带呼吸器娱乐潜水时死亡的病理及其机制——法医学观点

第十五届国际法庭科学大会

作者： Paul Fomes marie-Claire Tortel Jacques Tortel Bertrand Ludes 杨玉璞任嘉诚刘华 Institute of Forensic Medicine 2Place Mazas 75012 Paris and Department of Forensic SciencesCollege of Medicine Cochin Port-RoyalUnitersity of Paris（v）Fance Institute of Forensic Medicine of Strasbourg France Institute of Forensic Medicine of Strasbourg France Institute of Forensic Medicine of Strasbourg France

＜正＞我们的研究提供了关于娱乐潜水时意外事故的病理及其机制,它对完成尸检的医学人员或相关的法医学应用均有帮助。对此种潜水的装备和心理上的某些情况亦有助于对此类事件的理解。

关键词：潜水溺死病理学

Antioxidant acitivity in vitro and in vivo of a water-soluble polysaccharide isolated from Cordyceps gunnii （berk.） ***

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Antioxidant acitivity in vitro and in vivo of a water-solubl...

2009 International Conference of Natural Products and Traditional Medicine(ICNPTM’ 09)

作者： Zhen-yuan ZHU*a b Rongqiang LIUa Chuan-ling SIc Chang-mei ZHUa Yue-ru ZHONGa Shengfeng LIa Jing YUANa Jiaoping Zhoua Yong-min ZHANGd aKey Laboratory of Food Nutrition and Safety Ministry of Education College of Food Science and Biotechnology Tianjin University of Science and Technology Tianjin 300457 China bState Key Laboratory of Natural and Biomimetic Drugs Peking University Beijing 100191 P.R.China cTianjin Key Laboratory of Pulp & Paper College of Material Science and Chemical Engineering Tianjin University of Science and Technology Tianjin 300457 P.R.China dUniversité Pierre & marie Curie-Paris 6 Institut Parisien de Chimie Moléculaire UMR CNRS 7201 Tour 44/45 C.181 4 place Jussieu 75005 Paris france

Cordyceps sinensis（***.） is a well known tonic food or invigorant with broad-spectrum medicinal properties that is widely used in *** gunnii（berk.）Berk（***）,is also widely known as the Chinese rare caterpillar fungus and has similar pharmacological activities to *** water-soluble polysaccharide CPS50-I was extracted from the mycelia of *** and further purified by DEAE-Sephadex A-25 and Sephadex ***50-1 is a white powder contained 94.57% carbohydrate and four kinds of monosaccharides including xylose,mannose,glucose and galactose with a molar ratio of 0.13:0.89:0.54:*** vitro antioxidant assay,CPS50-I showed strong antioxidant activities of hydroxyl radical,superoxide radical and DPPH free radical *** antioxidant testing in vivo,the protective effect of CPS50-I was investigated against oxidation resistance in D-galactose（Dgal）-induced aging *** results showed that CPS50-I had an obviously protective effect against D-gal-induced aging mice.

关键词： Cordyceps gunnii Polysaccharide Characteristic Antioxidant D-gal

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动物物语

疯狂英语（初中天地） 2003年第27期 22-22页

作者： marie

You know that a rooster goes cock-a-doodle-doo in most English-speaking countries. But do you know that roosters in other countries make all sorts of different "sounds"? In Russia, a rooster goes Kukuriki. In Japan, it goes Kokekock-kom; in france, it goes Cocorico and in Germany, it goes Kikeriki. In Singapore, we say a cat goes Meow. In Ja-

关键词：德国日本物语俄罗斯人动物叫声法国人语系声音公鸡

Report of the first international workshop on onchocerciasis-associated epilepsy

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Infectious Diseases of Poverty 2018年第1期7卷 238-242页

作者： Robert Colebunders Michel Mandro Alfred K.Njamnshi Michel Boussinesq An Hotterbeekx Joseph Kamgno Sarah O’Neill Adrian Hopkins Patrick Suykerbuyk Maria-Gloria Basanez Rory J.Post Belen Pedrique Pierre-marie Preux Wilma A.Stolk Thomas B.Nutman Richard Idro Global Health Institute University of AntwerpAntwerpBelgium Provincial Health Division of Ituri BuniaDemocratic Republic of the Congo Department of Neurology Yaounde Central Hospital/University of Yaounde 1Brain Research Africa Initiative(BRAIN)YaoundeCameroon Institut de Recherche pour le Developpement(IRD) MontpellierFrance Centre for Research on Filariasis and other Tropical Diseases(CRFilMT) and Faculty of Medicine and Biomedical SciencesUniversity of Yaounde 1YaoundeCameroon Department of Public Health Institute of Tropical MedicineAntwerpBelgium Neglected and Disabling Diseases of Poverty Consultant KentUK London Centre for Neglected Tropical Disease Research Imperial College LondonLondonUK London School of Hygiene&Tropical Medicine and Liverpool John Moores University LondonUK Drugs for Neglected Diseases initiative GenevaSwitzerland Preux Pierre-marie INSERMUniversity LimogesCHU LimogesUMR_S 1094Tropical NeuroepidemiologyInstitute of Neuroepidemiology and Tropical NeurologyCNRS FR 3503 GEIST87000 LimogesFrance Department of Public Health Erasmus MCUniversity Medical Centre RotterdamRotterdamThe Netherlands Laboratory of Parasitic Diseases National Institutes of HealthBethesdaMarylandUSA Makerere University College of Health SciencesKampalaUganda

Background:Recently,several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy(OAE)may constitute an important but neglected public health problem in many countries where onchocerciasis is still *** text:On October 12-14th 2017,the first international workshop on onchocerciasis-associated epilepsy(OAE)was held in Antwerp,*** workshop was attended by 79 participants from 20 different *** research findings strongly suggest that *** is an important contributor to epilepsy,particularly in meso-and hyperendemic areas for *** with *** is associated with a spectrum of epileptic seizures,mainly generalised tonic-clonic seizures but also atonic neck seizures(nodding),and stunted *** is characterised by an onset of seizures between the ages of 3-18 *** working groups discussed topics such as how to 1)strengthen the evidence for an association between onchocerciasis and epilepsy,2)determine the burden of disease caused by OAE,3)prevent OAE,4)improve the treatment/care for persons with OAE and affected families,5)identify the pathophysiological mechanism of OAE,and 6)deal with misconceptions,stigma,discrimination and gender violence associated with *** OAE Alliance was created to increase awareness about OAE and its public health importance,stimulate research and disseminate research findings,and create partnerships between OAE researchers,communities,advocacy groups,ministries of health,non-governmental organisations,the pharmaceutical industry and funding ***:Although the exact pathophysiological mechanism underlying OAE remains unknown,there is increasing evidence that by controlling and eliminating onchocerciasis,OAE will also ***,OAE constitutes an additional argument for strengthening onchocerciasis elimination *** the high numbers of people with epilepsy

关键词： Onchocerciasis Epilepsy Nodding syndrome Nakalanga syndrome Prevalence Burden of disease Africa

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法国地方公共团体概念的辨析

华北科技学院学报 2013年第4期10卷 112-120页

作者：让-玛丽.蓬蒂埃施思璐法国埃克斯-马赛大学法国巴黎第一大学

法国地方分权的发展不仅关系到法律基本制度的建设,如公法人制度的建立和以法律形式明确各个权限的分配,而且涉及到机构的独立化、普遍选举的推动等等,以及公务法人的多样化发展和合理分类,最后还涉及建立必要合理的监督手段使地方的积... 详细信息

法国地方分权的发展不仅关系到法律基本制度的建设,如公法人制度的建立和以法律形式明确各个权限的分配,而且涉及到机构的独立化、普遍选举的推动等等,以及公务法人的多样化发展和合理分类,最后还涉及建立必要合理的监督手段使地方的积极性在中央的监控下良性有序地发挥。因此,对地方公共团体概念的把握是了解法国地方分权制度的关键。

关键词：法国公法地方公共团体公务法人地方分权制度监督手段

Numerical Key Results for Studying the Performance of TCP Traffic under Class-Based Weighted Fair Queuing System

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通讯和计算机（中英文版） 2016年第4期13卷 195-201页

作者： Mohamed E1 Hedi Boussada Jean marie Garcia Mounir Frikha Mobile Network and Multimedia SUP 'COM University of Carthage Tunis Tunisia Services and Architectures for Advanced Networks LAAS-CNRS Toulouse France

Ce0.9Ni0.1OY催化剂上甲烷部分氧化制合成气

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Ce0.9Ni0.1OY催化剂上甲烷部分氧化制合成气

第五届全国环境催化与环境材料学术会议

作者：单文娟刘昭斌由万胜 Matthieu Fleys Francois Lapicque Paul-marie Marquaire 辽宁师范大学化学化工学院功能材料化学研究所辽宁师范大学化学化工学院功能材料化学研究所辽宁师范大学化学化工学院功能材料化学研究所 Département de Chimie Physique des Réactions CNRS-ENSICBP451F-54001 NancyFrance Laboratoire des Sciences du Génie Chimique CNRS-ENSICBP451F-54001 NancyFrance Département de Chimie Physique des Réactions CNRS-ENSICBP451F-54001 NancyFrance

采用喷气式反应器考察了络合-燃烧方法制备的Ce-Ni-O催化剂甲烷部分氧化制合成气的催化性能。表征结果表明该催化剂中Ce、Ni强相互作用有利于氧的活化和转移,加速了碳物种的转化,有效地抑制了积碳。

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Aberrant expression of CD56 by circulating Sézary syndrome malignant T lymphocytes

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World Journal of Immunology 2013年第3期3卷 68-71页

作者： Nicolas Thonnart Caroline Ram-Wolff Martine Bagot Armand Bensussan Anne marie-Cardine INSERM U976 Saint Louis Hospital 75010 Paris France University Paris Diderot Sorbonne Paris Cité 75013 Paris France AP-HP Department of Dermatology Saint Louis Hospital 75010 Paris France

Sézary syndrome(SS) is an aggressive variant of cutaneous T cell lymphoma characterized by the presence of malignant T cells in the skin, peripheral blood and lymph nodes. The tumoral population typically displays a CD3+ CD4+ CD45RO+ memory T cell phenotype. We report a case of SS with an aberrant CD56+ immunophenotype. This patient presented with a generalized erythroderma and palpable small axillary lymph ***(stage IVA) was diagnosed on histological criteria and by the detection of a major T cell clone in skin and blood, an elevated CD4/CD8 T cell ratio and Sézary cells count > 1000/mm3. Beside the Sézary cell marker KIR3DL2, immunostainings revealed that two third of the malignant cells expressed CD56 but no other natural killer(NK) cell marker such as CD16, CD160 or NKp46. This atypical expression was not linked to an activation-dependent process and remained stable during the time course of the disease. No loss of the panT-cell markers CD2, CD3 or CD4 was detected while a complete down-modulation of CD26 was observed. Despite several lines of treatment, no durable amelioration was observed and patient died after 10 mo of follow-up. Because this CD4+ CD56+ SS case is the only one reported so far, the functional significance of CD56 expression remained difficult to assess in terms of aggressiveness and prognosis.

关键词： Cutaneous T cell lymphomas Sézary syndrome CD56