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Liver volumetric and anatomic assessment in living donor liver transplantation: The role of modern imaging and artificial intelligence

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World Journal of Transplantation 2023年第6期13卷 290-298页

作者： Mayara Machry Luis Fernando ferreira Angelica Maria Lucchese Antonio Nocchi Kalil Flavia Heinz Feier Department of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation Irmandade Santa Casa de Misericórdia de Porto AlegrePorto Alegre 90020-090Brazil Postgraduation Program in Medicine:Hepatology Federal University of Health Sciences of Porto AlegrePorto Alegre 90050-170Brazil

The shortage of deceased donor organs has prompted the development of alternative liver grafts for ***-donor liver transplantation(LDLT)has emerged as a viable option,expanding the donor pool and enabling timely transplantation with favorable graft function and improved long-term *** accurate evaluation of the donor liver’s volumetry(LV)and anatomical study is crucial to ensure adequate future liver remnant,graft volume and precise liver ***,ensuring donor safety and an appropriate graftto-recipient weight *** LV(MLV)using computed tomography has traditionally been considered the gold standard for assessing liver ***,the method has been limited by cost,subjectivity,and *** LV techniques employing advanced segmentation algorithms offer improved reproducibility,reduced variability,and enhanced efficiency compared to manual ***,the accuracy of automated LV requires further *** study provides a comprehensive review of traditional and emerging LV methods,including semi-automated image processing,automated LV techniques,and machine learning-based ***,the study discusses the respective strengths and weaknesses of each of the aforementioned *** use of artificial intelligence(AI)technologies,including machine learning and deep learning,is expected to become a routine part of surgical planning in the near *** implementation of AI is expected to enable faster and more accurate image study interpretations,improve workflow efficiency,and enhance the safety,speed,and cost-effectiveness of the *** preoperative assessment of the liver plays a crucial role in ensuring safe donor selection and improved outcomes in *** has inherent limitations that have led to the adoption of semi-automated and automated software ***,AI has tremendous potential for LV and segmentation;however,its widespread use is hindered

关键词： Liver transplantation Living-donor Diagnostic imaging Artificial intelligence Machine learning Deep learning

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Seasonal testicular changes in Dendropsophus minutus Peters, 1872 (Anura, Hylidae)

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BIOCELL 2012年第2期36卷 57-62页

作者： ADELINA ferreira MAHMOUD MEHANNA Universidade Federal de Mato Grosso(UFMT) Instituto de BiociênciasCuiabáMTBrasil Universidade Estadual Paulista Julio de Mesquita Filho(UNESP) Laboratório de Biologia de PeixesPós-graduação em ZoologiaBotucatuSPBrasil

The reproductive cycle in anurans may be either continuous or *** differences may be connected to seasonal climate changes and/or to anthropic *** adult male individuals of the Dendropsophus minutus species were collected during one year,in the municipality of Chapada dos Guimarães(Mato Grosso,Brazil).The testicles were studied under light and transmission electron *** variations were observed when the diameter of the seminiferous tubules and the thickness of the interstitial tissue were ***,changes in spermatogenesis were conspicuous and indicated that the reproductive cycle of *** in Chapada dos Guimarães is discontinuous and seems related to variations in air temperature and rainfall.

关键词： spermatogenesis reproduction anura ultrastructure Chapada dos Guimarães

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Evaluating seroprevalence to circumsporozoite protein to estimate exposure to three species of Plasmodium in the Brazilian Amazon

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Infectious Diseases of Poverty 2018年第1期7卷 448-459页

作者： Virginia Araujo Pereira Juan Camilo Sanchez-Arcila mariana Pinheiro Alves Vasconcelos Amanda Ribeiro ferreira Lorene de Souza Videira Antonio Teva Daiana Perce-da-Silva Maria Teresa Queiroz Marques Luzia Helena de Carvalho Dalma Maria Banic Luiz Cristovao Sobrino Porto Joseli Oliveira-ferreira Laboratory of Immunoparasitology Oswaldo Cruz Institute/FiocruzAv.Brasil 4365ManguinhosRio de JaneiroBrazil Institute of Infectology Emilio Ribas São PauloSao PauloBrazil Laboratory of Immunodiagnosis Departament of Biological SciencesNational School of Public Health/FiocruzRio de JaneiroBrazil Laboratory of Clinical Immunology Oswaldo Cruz Institute/FiocruzRio de JaneiroBrazil Laboratory of Histocompatibility and Cryopreservation–HLA of DHE/IBRAG/UERJ Rio de JaneiroBrazil Molecular Biology and Malaria Immunology Research Group Centro de Pesquisas Rene Rachou/FiocruzBelo HorizonteMinas GeraisBrazil

Background:Brazil has seen a great decline in malaria and the country is moving towards ***,for eventual elimination,the control program needs efficient tools in order to monitor malaria exposure and *** this study,we aimed to evaluate whether seroprevalence to the circumsporozoite protein(CSP)is a good tool for monitoring the exposure to and/or evaluating the burden and distribution of Plasmodium species in the Brazilian ***:Cross-sectional surveys were conducted in a rural area of Porto Velho,Rondônia *** infection was detected by microscopy and polymerase chain *** to the sporozoite CSP repeats of Plasmodium vivax,***,and ***(PvCS,PfCS,and PmCS)were detected using the enzyme-linked immunosorbent assay *** leukocyte antigen(HLA)-DRB1 and DQB1 genes were typed using Luminex®xMAP®***:The prevalence of immunoglobulin G against *** CSP peptide(62%)was higher than ***(49%)and ***(46%)CSP *** of the studied individuals had antibodies to at least one of the three peptides(72%),34%had antibodies to all three peptides and 28%were *** the majority of the population was not infected at the time of the survey,74.3%of parasite-negative individuals had antibodies to at least one of the ***,among individuals carrying the haplotypes DRB1*04~DQB1*03,there was a significantly higher frequency of PfCS responders,and DRB1*16~DQB1*03 haplotype for PvCS and PfCS *** contrast,HLA-DRB1*01 and HLA-DQB1*05 allelic groups were associated with a lack of antibodies to *** and *** CSP repeats,and the haplotype DRB1*01~DQB1*05 was also associated with non-responders,including non-responders to ***:Our results show that in low transmission settings,naturally acquired antibody responses against the CSP repeats of ***,***,and *** in a single cross-sectional study may n

关键词： Malaria Circumsporozoite protein Serological marker Human leucocyte antigen IgG antibody Porto Velho Rondônia Brazil

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Evidence-based Practice of Chinese Medicine in Physical Rehabilitation Science

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Chinese Journal of Integrative Medicine 2013年第10期19卷 723-729页

作者： Arthur de Sá ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Program of Rehabilitation ScienceCentro Universitario Augusto MottaRio de JaneiroRJBrazil(21041-021) Department of Physical Therapy UniversidadeSalgado de OliveiraNiteróiRJBrazil(21041-021)

Chinese medicine is among other traditional medical systems practiced either as a coadjutant intervention to Greek medicine or as the unique therapeutic intervention for illness prevention, treatment or rehabilitation. The complete spectrum from that traditional system includes acupuncture and moxibustion, herbal and food therapy, massage therapy （tuina）, physical exercises （taijiquan）, and breathing exercises （qigong）. In this article, it is presented several randomized controlled trials and systematic reviews on the application of all therapeutic modalities from Chinese medicine in the physical rehabilitation scenario. The discussed studies encompasses both ＂positive＂ and ＂negative＂ results of Chinese medicine intervention for disabilities due to illnesses of the nervous, musculoskeletal or cardiovascular systems. Additionally, the importance of the personalized approach for Chinese medicineand rehabilitation is emphasized together with the need for reproducible methods for pattern differentiation and intervention selection. Chinese medicine resources are recognized as promising methods for therapeutic rehabilitation and can be incorporated into the rehabilitation science. The wide variety of therapeutic resources explains why Chinese medicine is currently a multidisciplinary practice for health protection and promotion, early diagnosis and treatment as well as rehabilitation with roles in the public health care system.

关键词： rehabilitation physical therapy Chinese medicine

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Conflictive management of small mammals considered as pests： A long way to evidence-based policy making

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Current Zoology 2012年第2期58卷 353-357页

作者： Catarina ferreira Miguel DELIBES-MATEOS Instituto de Investigacion en Recursos Cinegeicos IREC （CSIC-UCLM-JCCM） Ronda de Toledo s/n E-13071 Ciudad Real SPAIN CIBIO Centro de Investigacao em Biodiversidade e Recursos Geneticos Campus Agrario de Vairao 4485-661 Vairao PORTUGAL

This paper discusses the controversial management decisions made by policy-makers worldwide regarding poisoning campaigns aimed to control small mammal populations, often considered harmful economic pests. Aside from considerations regarding the biological consequences of these campaigns, we argue that when society rejects all values of science and expertise then only badly supported and negligent decisions will be made about conservation and management issues. The extermination of small mammal species, some of which play crucial ecological roles in several regions of the world, is just an example of such discredit and misinformation. Without a strong commitment towards evidence-based policy-making, economic investments in research and development could be entirely compromised [Current Zoology58 (2): 353–357, 2012].

关键词：小型哺乳动物决策者管理所害虫基础证据宣传活动动物种群

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Investigation of possible relationship between atopic dermatitis and salivary biomarkers,stress,and sleep disorders

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World Journal of Clinical Cases 2023年第17期11卷 3958-3966页

作者： Juliany Estefan Dennis de Carvalho ferreira Fernanda Sampaio Cavalcante Kátia Regina Netto dos Santos Marcia Ribeiro Dermatologia Pediátrica Universidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil Faculdade de Enfermagem Departamento de Fundamentos de EnfermagemUniversidade do Estado do Rio de JaneiroRio de Janeiro 20551030Brazil Departamento de Clínica Médica Instituto de Ciências MédicasUniversidade Federal do Rio de JaneiroCampus MacaéRio de Janeiro 27930-560Brazil Departamento de Microbiologia Médica Instituto de Microbiologia Paulo de GóesUniversidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil Genética médica Instituto de Puericultura e Pediatria Martagão Gesteira/Universidade Federal do Rio de JaneiroRio de Janeiro 21941630Brazil

Atopic dermatitis(AD)is a chronic,relapsing,multifactorial inflammatory disease with genetic,environmental,and immunological *** quality of life and sleep of patients and their families are affected by AD,which triggers stress,described as one of the factors that worsens *** biomarkers such as cortisol,alpha-amylase,chromogranin A,and melatonin have been associated with stress and sleep ***,the evaluation of stress and sleep disorders using salivary biomarkers in AD patients is *** review aims to describe the possible relationship between atopic dermatitis and stress,sleep disorders,and salivary biomarkers,seeking to contribute to better understanding and clinical management of *** descriptive study is characterized as a narrative literature review.A literature search was conducted of studies published in English and Portuguese between January 2012 and October 2022 that are available in electronic media from various databases,such as Scientific Electronic Library Online,Latin American and Caribbean Literature on Health Sciences,and *** is associated with different degrees of impact on the lives of individuals who present with the *** stress may induce changes in saliva composition and worsen AD;at the same time,the severity of the disease may be associated with emotional *** studies are needed to assess and correlate AD severity,stress,and sleep disturbances with salivary biomarkers in order to better understand this association.

关键词： Atopic dermatitis Sleep Psychological stress Chromogranin A Melatonin Cortisol

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Evaluation of Geometric Quality of Weld Beads in the Joining of Carbon Steel Pipelines with Single Pass

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Journal of Power and Energy Engineering 2013年第7期1卷 1-5页

作者： José Eduardo Silveira leal Thonson ferreira Costa Rosenda Valdés Arencibia Federal Universityof Uberlandia Avenida Joao Naves de Avila2121Campus Santa MonicaBloco 5FCEP 38400-902Uberlandia-MGBrazil

This work presents the uncertainty evaluation associated with the measurement of linear parameters that define the weld geometry, specifically the width, using a profile projector, in order to meet the current technical standards. The following steps were proposed and implemented: identification of linear parameters that define the weld geometry;identification and study of variables that affect the measurement of these parameters;the adoption of the mathematical model to estimate the uncertainty;planning and execution of experiments for data collection, calculation of uncertainty and, finally, analysis and discussion of the results. Through the results analysis it was concluded that the weld in overhead position produces the lowest front bead width values and the vertical weld produces the largest width values. The expanded uncertainty values were between 0.016 mm and 0.075 mm for all measurements, and the overhead position showed, on average, the highest values.

关键词： Welding Weld Bead Geometry Profile Projector Uncertainty

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Lessons learnt from a deep excavation for future application of the observational method

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第3期10卷 468-485页

作者： Raul Fuentes Anton Pillai Pedro ferreira School of Civil Engineering University of LeedsLeedsLS2 9JTUK Ove Arup and Partners 13 Fitzroy StreetLondonW1T 4BQUK Department of Civil Environmental&Geomatic EngineeringUniversity College LondonChadwick BuildingGower StreetLondonWC1E 6BTUK

This paper draws lessons learnt from a comprehensive case study in overconsolidated clay. Apart from the introduction of the case study, including field measurements, the paper draws on the observations and a three-dimensional（3 D） numerical analysis to discuss the implications of observations in the application of the observational method（OM） in the context of the requirements of EUROCODE 7（EC7）.In particular, we focus on corner effects and time-dependent movements and provide initial guidance on how these could be considered. Additionally, we present the validation of a new set of parameters to check that it provides a satisfactory compliance with EC7 as a set of design parameters. All these findings and recommendations are particularly important for those who want to use the OM in similar future projects.

关键词： Deep excavation Basement Ground movements Wall movements Retaining wall Corner effects Time-dependent movements

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Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

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Bioactive Materials 2023年第1期19卷 268-281页

作者： Arwa Daghrery Jessica A.ferreira Jinping Xu Nasim Golafshan Darnell Kaigler Sarit B.Bhaduri Jos Malda Miguel Castilho Marco C.Bottino Department of Cariology Restorative Sciencesand EndodonticsSchool of DentistryUniversity of MichiganAnn ArborMIUnited States Department of Restorative Dental Sciences School of DentistryJazan UniversityJazanKingdom of Saudi Arabia Department of Orthopedics University Medical Center UtrechtUtrechtthe Netherlands Regenerative Medicine Center Utrechtthe Netherlands Department of Periodontics and Oral Medicine School of DentistryUniversity of MichiganAnn ArborMIUnited States Department of Mechanical Industrial and Manufacturing EngineeringUniversity of ToledoToledoOHUnited States EEC Division Directorate of EngineeringThe National Science FoundationAlexandriaVAUnited States Department of Clinical Sciences Faculty of Veterinary MedicineUtrecht UniversityUtrechtthe Netherlands Department of Biomedical Engineering Eindhoven University of TechnologyEindhoventhe Netherlands Institute for Complex Molecular Systems Eindhoven University of TechnologyP.O.Box 5135600 MB Eindhoventhe Netherlands Department of Biomedical Engineering College of EngineeringUniversity of MichiganAnn ArborMIUnited States

Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-supporting *** limited successful outcomes of clinically available approaches underscore the need for therapeutics that cannot only provide structural guidance to cells but can also modulate the local immune ***,three-dimensional melt electrowritten(i.e.,poly(ε-caprolactone))scaffolds with tissue-specific attributes were engineered to guide differentiation of human-derived periodontal ligament stem cells(hPDLSCs)and mediate macrophage *** investigated tissue-specific scaffold attributes comprised fiber morphology(aligned ***)and highly-ordered architectures with distinct strand spacings(small 250μm and large 500μm).Macrophages exhibited an elongated morphology in aligned and highly-ordered scaffolds,while maintaining their round-shape on randomly-oriented fibrous *** of periostin and IL-10 were more pronounced on the aligned and highly-ordered *** hPDLSCs on the scaffolds with 500μm strand spacing show higher expression of osteogenic marker(Runx2)over 21 days,cells on randomly-oriented fibrous scaffolds showed upregulation of M1 *** an orthotopic mandibular fenestration defect model,findings revealed that the tissue-specific scaffolds(i.e.,aligned fibers for periodontal ligament and highly-ordered 500μm strand spacing fluorinated calcium phosphate[F/CaP]-coated fibers for bone)could enhance the mimicking of regeneration of natural periodontal tissues.

关键词： Periodontitis Melt electrowriting 3D printing Inflammation Periodontal regeneration Scaffold

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Spent coffee grounds as a renewable source of energy: An analysis of bulk powder flowability

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Particuology 2019年第2期17卷 92-100页

作者： L. Massaro Sousa M.C. ferreira Drying Center for Pastes Suspensions and Seeds. Chemical Engineering Department Federal University of Sao Carlos. P.O. Box 676 13565-905 Sao Carlos Brazil

The main use for spent coffee grounds (SCG) produced in the soluble coffee industry is thermal energy generation in the industry itself. The SCG are processed using operations that are strongly dependent on powder flow behavior. In this study, we evaluated two classical flowability in dices of non-consolidated SCG powders: the angle of repose (AoR), and the Hausner ratio (HR). The influences of the mean particle diameter, particle size distribution (PSD), and water content on the AoR and HR values of SCG were analyzed for powders with a mean particle size range of 225-550 μm. For powders with a mean particle size close to 350 μm and for mixtures containing more than 40% fine particles, the HR (>1.35) and AoR (>45 °) values were characteristic of poor flowability. The AoR was sensitive to the powder PSD, and powders with similar mean particle sizes had higher AoR values when the PSD was larger. For powders w让h water contents up to 50%, the flowability indices were not greatly affected by the water content. A modified linear-mixture packing model was used to predict the packed bed void fractions for binary and ternary mixtures of the three base powders. The model was used to construct a ternary diagram to estimate the HR values of the mixtures. An equation was fitted to correlate HR and AoR. The proposed diagram and the equation provide insight into flow behavior and could be used for process design of industrial plants that handle SCG.

关键词： Spent coffee ground Biomass Flowability Hausner ratio Angle of repose

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