检索结果-南通市图书馆

Differential expression of the fractalkine chemokine receptor （CX3CR 1） in human rnonocytes during differentiation

Cellular & Molecular Immunology 2015年第6期12卷 669-680页

作者： Cecilia Analia Panek maria victoria ramos maria Pilar Mejias maria Iimena Abrey-Recalde Romina Iimena Fernandez-Brando maria Soledad Gori Gabriela Veronica Salamone2 Marina Sandra Palermo Laboratorio de Patogenesis e Inmunologfa de Procesos Infecciosos Instituto de Medicina Experimental (IMEX CONICET) Academia Nacional de Medicina Buenos Aires Argentina and Laboratorio de Celulas Presentadoras de Antfgeno y Respuesta Inflamatoria IMEX-CONICET Academia Nacional de Medicina Buenos Aires Argentina

Circulating monocytes （Mos） may continuously repopulate macrophage （MAC） or dendritic cell （DC） populations to maintain homeostasis. MACs and DCs are specialized cells that play different and complementary immunological functions. Accordingly, they present distinct migratory properties. Specifically, whereas MACs largely remain in tissues, DCs are capable of migrating from peripheral tissues to lymphoid organs. The aim of this work was to analyze the expression of the fractalkine receptor （CX3CR1） during the monocytic differentiation process. Freshly isolated Mos express high levels of both CX3CR1 mRNA and protein. During the Mo differentiation process, CX3CR1 is downregulated in both DCs and MACs. However, MACs showed significantly higher CX3CR1 expression levels than did DC. We also observed an antagonistic CX3CR1 regulation by interferon （IFN）-γ and interleukin （IL）-4 during MAC activation through the classical and alternative MAC pathways, respectively. IFN-γinhibited the loss of CX3CR1, but IL-4 induced it. Additionally, we demonstrated an association between CX3CR1 expression and apoptosis prevention by soluble fractalkine （sCX3CL1） in Mos, DCs and MACs. This is the first report demonstrating sequential and differential CX3CR1 modulation during Mo differentiation. Most importantly, we demonstrated a functional link between CX3CR1 expression and cell survival in the presence of sCX3CL1.

关键词： dendritic cells fractalkine receptor macrophages monocytes survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Investigation of electrophysical, photo- and gas-sensitive properties of ZnO–SnO_(2) sol–gel fflms

引用

Journal of Advanced Dielectrics 2024年第1期14卷 42-50页

作者： Irina A.Gulyaeva Alexandra P.Ivanisheva maria G.Volkova victoria Yu.Storozhenko Soslan A.Khubezhov Ekaterina M.Bayan Victor V.Petrov Research and Education Centre“Microsystem Technics and Multisensory Monitoring Systems”Southern Federal University Russia Department of Chemistry Southern Federal UniversityRussia Department of Physics North-Ossetian State University362025 VladikavkazRussia Department of Physics and Engineering ITMO University191002 PetersburgRussia

Thin nanocomposite fflms based on tin dioxide with a low content of zinc oxide(0.5–5 mol.%)were obtained by the sol–gel *** synthesized fflms are 300–600 nm thick and contains pore sizes of 19–29 *** resulting ZnO–SnO_(2) fflms were comprehensively studied by atomic force and Kelvin probe force microscopy,X-ray diffraction,scanning electron microscopy,and high-resolution X-ray photoelectron spectroscopy *** photoconductivity parameters on exposure to light with a wavelength of 470 nm were also *** study of the photosensitivity kinetics of ZnO–SnO_(2) fflms showed that the fflm with the Zn:Sn ratio equal to 0.5:99.5 has the minimum value of the charge carrier generation time *** of the activation energy of the conductivity,potential barrier,and surface potential of ZnO–SnO_(2) fflms showed that these parameters have maxima at ZnO concentrations of 0.5 mol.%and 1 mol.%.Films with 1 mol.%ZnO exhibit high response values when exposed to 5–50 ppm of nitrogen dioxide at operating temperatures of 200℃ and 250℃.

关键词： Sol–gel method,ZnO–SnO_(2) films gas-sensitive properties surface potential potential barrier conduction activation energy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Co-Optimization of Behind-the-Meter and Front-of-Meter Value Streams in Community Batteries

引用

Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 334-345页

作者： Carmen Bas Domenech Antonella maria De Corato Pierluigi Mancarella University of Melbourne Parkville 2010VictoriaAustralia Department of Electrical and Electronic Engineering The University of ManchesterManchesterU.K. IEEE

Community batteries(CBs)are emerging to support and even enable energy communities and generally help consumers,especially space-constrained ones,to access potential techno-economic benefits from storage and support local grid ***,the economic viability of CB projects is often *** this regard,typical feasibility studies assess CB value for behind-the-meter(BTM)operation or whole-sale market participation,i.e.,front-of-meter(FOM).This work proposes a novel techno-economic operational framework that allows systematic assessment of the different options and introduces a two-meter architecture that co-optimizes both BTM and FOM benefits.A real CB project application in Australia is used to demonstrate the significant two-meter co-optimization opportunities that could enhance the business case of CB and energy communities by multi-service provision and value stacking.

关键词： Behind-the-meter community battery distributed energy resource(DER) energy community front-of-meter value stacking

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison between Care Strategies for Patients with Osteoarthritis of the Hands Based on the Use of Joint Protection, Assistive Technology and Exercises

引用

Open Journal of Orthopedics 2024年第7期14卷 295-311页

作者： Daniele dos Santos Scarcella Talita Dias da Silva victoria Yanara Hernandes da Silva maria Cândida de Miranda Luzo Selma Lancman Marcia Uchoa de Rezende Carlos Bandeira de Mello Monteiro Instituto de Ortopedia e Traumatologia Hospital das Clnicas HCFMUSP Faculdade de Medicina Universidade de So Paulo So Paulo Brazil Programa de Ps-Graduao em Cincias da Reabilitao Faculdade de Medicina Universidade de So Paulo So Paulo Brazil Escola de Artes Cincias e Humanidades Universidade de So Paulo So Paulo Brazil

Background: Osteoarthritis (OA) is a disabling disease that can affect 6% to 12% of the adult population and more than a third of people over 65 years of age. Purpose: To assess whether a group of people with hand osteoarthritis (hOA) who received different types of treatment improved their function after two years of follow-up. Method: The entire sample (n = 97) underwent three follow-up assessments regarding anthropometric parameters of the upper limbs and ability to perform functional activities. Subsequently, the sample was divided into two groups for the intervention periods, called the First Period (n = 73) and the Second Period (n = 24);the First Period kept the same protocol with orientations, and the Second Period went to an intervention with orientation strength exercises and use of orthosis. Findings: In the separate analysis of the three questions of the DASH pain module, no differences were found between the assessment moments for groups of guidelines, treatment, or symptoms. Significant effects were observed for F(2, 162) = 3.5, p = 0.033, η2 = 0.04, and interaction for moments and intervention F(2, 162) = 4.3, p = 0.016, η2 = 0.05. Implications: It can be concluded that only guidance treatment does not benefit patients with hand osteoarthritis. In contrast, guidance, exercise, and orthosis treatment can significantly improve the disease.

关键词： Hand Osteoarthritis Hand Deformities Occupational Therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recent progress on bimetallic NiCo and CoFe based electrocatalysts for alkaline oxygen evolution reaction: A review

引用

Journal of Energy Chemistry 2022年第4期31卷 101-137页

作者： Gebrehiwet Abrham Gebreslase maria victoria Martínez-Huerta maria Jesus Lázaro Instituto de Carboquímica CSIC.Miguel LuesmaCastán 450018ZaragozaSpain Instituto de Catálisis y Petroleoquímica CSIC.Marie Curie 228049MadridSpain

The deployment of hydrogen as an energy carrier is found to be a vital alternative fuel for the future. It is expected that water electrolysis, powered by renewable energy sources, be able to scale-up hydrogen production. However, the reaction kinetic of oxygen evolution reaction(OER) is a sluggish process, which predominantly limits the efficiency of water electrolysis. This review recapitulates the recent progress and efforts made in the design and development of two selected earth-abundant bimetallic electrocatalysts(Ni Co and Co Fe) for alkaline OER. Each bimetal electrocatalyst is thoroughly outlined and discussed in five sub-sections, including bimetal(oxy) hydroxides, Layered double hydroxides(LDHs) structures,oxides, composites, alloy and nanostructured electrocatalysts, and assembled with ***, a brief introduction to an in situ/operando characterization techniques and advantages for monitoring the structure of the electrocatalysts is provided. Finally, a summary outlining the challenges and conceivable approaches to advance OER performance is highlighted and discussed.

关键词： Water electrolysis Oxygen evolution reaction Bimetallic electrocatalyst Nickel Cobalt and iron

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Redox regulation of the immune response

引用

Cellular & Molecular Immunology 2022年第10期19卷 1079-1101页

作者： Gerwyn Morris maria Gevezova victoria Sarafian Michael Maes Deakin University IMPACT-the Institute for Mental and Physical Health and Clinical TranslationSchool of MedicineBarwon HealthGeelongVICAustralia Department of Medical Biology Medical University-PlovdivPlovdivBulgaria Research Institute at Medical University-Plovdiv PlovdivBulgaria Department of Psychiatry Faculty of MedicineKing Chulalongkorn Memorial HospitalBangkokThailand Department of Psychiatry Medical University of PlovdivPlovdivBulgaria

The immune-inflammatory response is associated with increased nitro-oxidative *** aim of this mechanistic review is to examine:(a)the role of redox-sensitive transcription factors and enzymes,ROS/RNS production,and the activity of cellular antioxidants in the activation and performance of macrophages,dendritic cells,neutrophils,T-cells,B-cells,and natural killer cells;(b)the involvement of high-density lipoprotein(HDL),apolipoprotein A1(ApoA1),paraoxonase-1(PON1),and oxidized phospholipids in regulating the immune response;and(c)the detrimental effects of hypernitrosylation and chronic nitro-oxidative stress on the immune *** redox changes during immune-inflammatory responses are orchestrated by the actions of nuclear factor-κB,HIF1α,the mechanistic target of rapamycin,the phosphatidylinositol 3-kinase/protein kinase B signaling pathway,mitogen-activated protein kinases,5'AMP-activated protein kinase,and peroxisome proliferator-activated *** performance and survival of individual immune cells is under redox control and depends on intracellular and extracellular levels of ROS/*** are heavily influenced by cellular antioxidants including the glutathione and thioredoxin systems,nuclear factor erythroid 2-related factor 2,and the HDL/ApoA1/PON1 *** nitro-oxidative stress and hypernitrosylation inhibit the activity of those antioxidant systems,the tricarboxylic acid cycle,mitochondrial functions,and the metabolism of immune *** conclusion,redox-associated mechanisms modulate metabolic reprogramming of immune cells,macrophage and T helper cell polarization,phagocytosis,production of pro-versus anti-inflammatory cytokines,immune training and tolerance,chemotaxis,pathogen sensing,antiviral and antibacterial effects,Toll-like receptor activity,and endotoxin tolerance.

关键词： Oxidative and nitrosative stress Immune response Inflammation Antioxidants Physiological stres

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neotropical mustelids: fecal metabolome diversity and its potential for taxonomic discrimination

引用

Integrative Zoology 2023年第3期18卷 518-529页

作者： Lana Resende de ALMEIDA Marina Amaral ALVES Ana maria Obino MASTELLA Rafael GARRETT maria João ramos PEREIRA Bird and Mammal Evolution Systematics and Ecology LabPrograma de Pós-Graduação em Biologia AnimalUniversidade Federal do Rio Grande do SulPorto AlegreRio Grande do SulBrazil Programa de Pós-Graduação em Biologia Animal Universidade Federal do Rio Grande do SulPorto AlegreRio Grande do SulBrazil Chemistry Institute Metabolomics Laboratory(LabMeta–LADETEC/IQ–UFRJ)Avenida Horácio MacedoFederal University of Rio de JaneiroRio de JaneiroRJBrazil Walter Mors Institute of Research on Natural Products Universidade Federal do Rio de JaneiroRio de JaneiroRJBrazil

Chemical proﬁles of non-invasive biological material,such as feces,have great potential to study elusive animals or those with low population ***,we use a metabolomic approach to evaluate Neotropical mustelids as a biological model to describe the diversity of the metabolites present in fecal samples,as well as to evaluate the potential of chemical proﬁles for taxonomic *** collected fecal samples from captive individuals of 5 species of mustelids occurring in Brazil and analyzed them by liquid chromatography coupled to high-resolution mass *** 200 compounds have been annotated;“bile acids,alcohols and derivatives”was the most expressive class in the metabolome of all the *** successfully discriminated 3 taxonomic groups:1—tayra(Eira barbara);2—otters(Lontra longicaudis and Pteronura brasiliensis;1);and 3—grisons(Galictis vittata and Galictis cuja).Several compounds seemed to be associated with food intake and the digestive process,while others were found for theﬁrst time in Neotropical *** concluded that mustelids show high metabolome diversity and that species-speciﬁc identiﬁcation through metabolomic proﬁles is possible,thus contributing to the development and implementation of additional non-invasive approaches in the study of mustelids.

关键词： chemical proﬁles ecology high-resolution mass spectrometry metabolomics Mustelidae

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A comprehensive approach to the delayed treatment of post-burn facial scars

引用

中国整形与重建外科(英文) 2023年第3期5卷 159-162页

作者： victoria Ivanovna Polshina maria Cervatiuc Igor Vladimirovich Reshetov Alim Arsenovich Nebejev Eldor Jonnazarov Department of Oncology Radiotherapy and Plastic SurgeryI.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow 119435Russia Department of Oncology and Plastic Surgery Academy of Postgraduate Education of the FSBI FSCC Federal Medico-Biological Agency of RussiaMoscow 119435Russia Department of Ophthalmology I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow 119021Russia

Background:Damage to the skin and underlying tissues due to thermal burns is *** the success of modern medicine,repairing thermal damage to the skin is a difficult task in reconstructive plastic surgery because of the nature of the damage and the regenerative *** post-burn changes are associated with different depths of damage when areas of deep damage are combined with more superficial ***:We described a clinical case of the staged surgical treatment of a cicatricial deformity of the buccalperiorbital-perioral region resulting from a childhood burn injury from a hot *** 44-year-old patient complained of an aesthetic and functional deformity of the buccal-periorbital-perioral region and had previously undergone repeated nonsurgical ***:A comprehensive approach to the surgical treatment of a patient with post-burn deformities using a diplene adhesive membrane directly affected the stage of the surgical treatment and contributed to improved functional and aesthetic ***:The positive treatment results with preserved contraction and relaxation processes of the facial muscles as well as satisfactory aesthetic results allow us to recommend the use of a biodegradable diplene film during facial reconstructive operations.

关键词： Thermal burn Facial scarring Diplene film Buccal-periorbital-perioral region Adhesive membrane Deformation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nasal sill reconstruction with the Abbe flap after skin cancer resection:A case report

引用

Chinese Journal Of Plastic and Reconstructive Surgery 2023年第2期5卷 64-67页

作者： Renata Fernanda ramos Marcante Oona Tomiê Daronch Murilo Sgarbi Secanho maria Madalena Silva Department of Plastic Surgery State University of Sao PauloBotucatuSao Paulo 18618-687Brazil

Local flaps are widely known as the best option for partial nasal reconstructions depending on donor tissue laxity,vascularization,and defect shape and *** nasolabial flap is used more often in the nasal *** larger defects,greater tissue mobilization with larger scars or free flaps is ***,the Abbe flap has been used for lip reconstruction in patients with cleft lip *** allows less retraction than other local flaps or skin grafts in patients with large defect sizes and great defect *** study reported on the application of the Abbe flap for nasal sill reconstruction on a 71-year-old female patient with nasal sill basal cell carcinoma who had undergone resection surgery with a posterior lip switch operation with satisfactory *** application of the Abbe flap could be considered in patients with multiple previous surgeries and at risk for necrosis.

关键词： Surgical flaps Myocutaneous flap Nose Nasal diseases Nasal defects Neoplasms Basal cell

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Progress of the Modeling Approach on Land Change Science： Comments on Modelling the Dynamics and Consequences of Land System Change

引用

Journal of Geographical Sciences 2012年第3期22卷 575-576页

作者： maria victoria Ortega Espaldon School of Environmental Science and Management University of the Philippines

Land system change has never been out of human concerns. It is always one of the hottest themes in global environmental change research （Seto et al., 2002; Gutman et al., 2004）. With the development of research on land use change and the Global Land Project, it is necessary to explore the interactions and associations among various factors in the land system from a systematic perspective to recognize the causes and effects of land system change.

关键词：模型方法新进展动力学土地系统简评科学效应模拟

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：