检索结果-南通市图书馆

brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

引用

Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-Mañé Laia Just-borràs Marta balanyà-Segura Aleksandra Polishchuk Laura Nadal Marta Tomàs Carolina Silvera-Simón Manel M.santafé maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase b receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated Trkb/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorb

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Impact of Inoculum Preparation Media on Pollutant Removal through Phycoremediation of Agricultural Drainage Water by Desmodesmus sp.

引用

国际实验植物学杂志(英文) 2023年第10期92卷 2875-2890页

作者： Asmaa salah Hoda sany Abo el-Khair b.el.sayed Reham M.el-bahbohy Heba I.Mohamed Ayman Amin Plant Physiology Division Department of Agricultural BotanyFaculty of AgricultureCairo UniversityGizaP.O.Box 12613Egypt Algal biotechnology Unit National Research CentreDokkiGiza12622Egypt biological and Geological Science Department Faculty of EducationAin Shams UniversityCairo11341Egypt

Water is the most essential natural resource for the future *** production is extensively water-dependent and a significant polluter of water ***,this work investigated the effect of two different preparation media[bold’s basal Medium(bbM)and Domiati cheese whey(DCW)]for agricultural drainage water(ADW)*** treatments were incubated for 6 *** to the results of biomass productivity,specific growth rate,photosynthetic pigments,and biochemical composition,Desmodesmus *** grow in drainage water without *** two treatments significantly reduced the concentration of nitrate,phosphate,chemical oxygen demand,and sodium in ***,using cheese whey with bbM as inoculum preparation media enhanced the lipid accumulation in the algal biomass(25.4%w/w)and gave the best biodiesel properties among ***,combining remediation of drainage water with microalgae mass production can achieve the sustainability of agriculture.

关键词： Desmodesmus sp. drainage water nutrients recycle photosynthetic pigments phycoremediation water scarcity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microbial detoxification of metalaxyl in aquatic system

引用

Journal of Environmental Sciences 2008年第3期20卷 262-267页

作者： Ahmed H. Massoud Aly S. Derbalah el.sayed. b. belal Pesticides Department Faculty of Agriculture Kafr El-Sheikh University. Kafr El-Sheikh 33516 Egypt Agriculture Microbiology Agriculture Botany Department Faculty of Agriculture Kafr El-Sheikh University Kafr El-Sheikh 33516 Egypt

Four microorganisms, Pseudomonas sp. （ER2）, Aspergillus niger （ER6）, Cladosporium herbarum （ER4） and Penicilluim sp. （ER3）, were isolated from cucumber leaves previously treated with metalaxyl using enrichment technique. These isolates were evaluated for detoxification of metalaxyl at the recommended dose level in aquatic system. The effect of pH and temperature on the growth ability of the tested isolates was also investigated by measuring the intracellular protein and mycelia dry weight for bacterial and fungal isolates, respectively. Moreover, the toxicity of metalaxyl after 28 d of treatment with the tested isolates was evaluated to confirm the complete removal of any toxic materials （metalaxyl and its metabolites）. The results showed that the optimum degree pH for the growth of metalaxyl degrading isolates （bacterial and fungal isolates） was 7. The temperature 30℃ appeared to be the optimum degree for the growth of either fungal or bacterial isolates. The results showed that Pseudomonas sp. （ER2） was the most effective isolate in metalaxyl degradation followed by Aspergillus niger （ER6）, Cladosporium herbarum （ER4） and Penicilluim sp. （ER3）, respectively. There is no toxicity of metalaxyl detected in the supematant after 28 d of treatment with Pseudomonas sp. （ER2）. The results suggest that bioremediation by Pseudomonas sp. （ER2） isolate was considered to be effective method for detoxification of metalaxyl in aqueous media.

关键词： metalaxyl biodegradation microorganisms, toxicity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of Pumping Height and Repeated Pumping in Atlantic salmon salmo salar

引用

Natural Resources 2016年第6期7卷 377-383页

作者： Åsa maria Espmark Kjell Ø. Midling Jonatan Nilsson Odd-børre Humborstad Nofima AS Sunndals&oslash ra Norway Nofima AS Troms&oslash Norway Institute of Marine Research Bergen Norway

The aim of this study was to evaluate the effects of pumping height and repeated pumping on the generalized stress response and gross injuries in harvest sized Atlantic salmon. Fish pumped from a net pen at either high (5.2 m) or low (3.6 m) pumping heights showed an elevated, but not severe physiological stress response (pH, pCOb>2b>, lactate, potassium, haematocrit, and sodium) compared to fish netted (not pumped), while effects of different pumping heights were overall not demonstrated. Repeated pumping (either 3 or 6 times) also caused an increase in stress response (pH, pCOb>2b>, pOb>2b>, lactate, potassium and sodium) compared to control fish, and a positive dose-response relationship was found for lactate. No fish died as a result of pumping, nor were injuries observed that could exclusively be attributed to pumping. In conclusion, although elevated from the control groups, the stress response following increasing pumping height and repeated pumping as conducted in these experiments were not indicative of causing severe stress or injuries.

关键词： Handling Pumping Height Repeated Pumping Atlantic salmon Stress Welfare

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Development and Application of Detection Methods for Capture and Transcription elongation Rate of bacterial Nascent RNA

引用

生物化学与生物物理进展 2024年第9期51卷 2249-2260页

作者： LI Yuan-Yuan WANG Yu-Ting WU Zi-Chun LI Hao-Xuan FEI Ming-Yue SUN Dong-Chang GUALERZI O.Claudio FAbbRETTI Attilio GIULIODORI Anna maria MA Hong-Xia HE Cheng-Guang Engineering Research Center of the Chinese Ministry of Education for bioreactor and Pharmaceutical Development College of Life SciencesJilin Agricultural UniversityChangchun 130118China School of biosciences and Veterinary Medicine University of CamerinoCamerino(MC)62032Italy College of biotechnology and bioengineering Zhejiang University of TechnologyHangzhou 310014China

Objective Detection and quantification of RNA synthesis in cells is a widely used technique for monitoring cell viability,health,and metabolic *** exposure to environmental stimuli,both the internal reference gene and target gene would be *** a result,it is imperative to consider the accurate capture of nascent RNA and the detection of transcriptional levels of RNA following environmental *** study aims to create a Click Chemistry method that utilizes its property to capture nascent RNA from total RNA that was stimulated by the *** The new RNA was labeled with 5-ethyluridine(5-EU)instead of uracil,and the azido-biotin medium ligand was connected to the magnetic sphere using a combination of“Click Chemistry”and magnetic bead *** the new RNA was captured and the transcription rate of 16S rRNA was detected by fluorescence molecular beacon(M.b.)and quantitative reverse transcription PCR(qRT-PCR).Results The bacterial nascent RNA captured by“Click Chemistry”screening can be used as a reverse transcription template to form *** with the fluorescent molecular beacon M.b.1,the synthesis rate of rRNA at 37℃is 1.2 times higher than that at 15℃.The 16S rRNA gene and cspI gene can be detected by fluorescent quantitative PCR,it was found that the measured relative gene expression changes were significantly enhanced at 25℃and 16℃when analyzed with nascent RNA rather than total RNA,enabling accurate detection of RNA transcription *** Compared to other article reported experimental methods that utilize screening magnetic columns,the technical scheme employed in this study is more suitable for bacteria,and the operation steps are simple and easy to implement,making it an effective RNA capture method for researchers.

关键词： nascent RNA selection Click Chemistry fluorescence molecular beacon

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Congruence Pairs of Decomposable MS-Algebras

引用

Chinese Annals of Mathematics,Series b 2021年第4期42卷 561-574页

作者： sanaa el-ASsaR Abd el-Mohsen bADAWY Department of Mathematics Faculty of ScienceTanta UniversityTantaEgypt

In this paper,the authors first introduce the concept of congruence pairs on the class of decomposable MS-algebras generalizing that for principal MS-algebras(see[13]).They show that every congruence relationθon a decomposable MS-algebra L can be uniquely determined by a congruence pair(θ_(1),θ_(2)),whereθ_(1)is a congruence on the de Morgan subalgebra L^(∞)of L andθ_(2)is a lattice congruence on the sublattice D(L)of *** obtain certain congruence pairs of a decomposable MS-algebra L via central elements of ***,they characterize the permutability of congruences and the strong extensions of decomposable MS-algebras in terms of congruence pairs.

关键词： MS-Algebras Decomposable MS-algebras Congruence pairs Strong extension Permutability Congruence lattices

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improved Supervised and Unsupervised Metaheuristic-based Approaches to Detect Intrusion in Various Datasets

引用

Computer Modeling in Engineering & Sciences 2023年第10期137卷 265-298页

作者： Ouail Mjahed salah el Hadaj el Mahdi el Guarmah Soukaina Mjahed Faculty of Sciences and Technology Department of Computer SciencesCadi Ayyad UniversityMarrakech40000Morocco Mathematics and Informatics Department Royal Air SchoolMarrakech40000Morocco

Due to the increasing number of cyber-attacks,the necessity to develop efficient intrusion detection systems(IDS)is more imperative than *** IDS research,the most effectively used methodology is based on supervised Neural Networks(NN)and unsupervised clustering,but there are few works dedicated to their hybridization with metaheuristic *** intrusion detection data usually contains several features,it is essential to select the best ones *** Discriminant Analysis(LDA)and t-statistic are considered as efficient conventional techniques to select the best features,but they have been little exploited in IDS ***,the research proposed in this paper can be summarized as follows.a)The proposed approach aims to use hybridized unsupervised and hybridized supervised detection processes of all the attack categories in the CICIDS2017 ***,owing to the large size of the CICIDS2017 Dataset,only 25%of the data was used.b)As a feature selection method,the LDAperformancemeasure is chosen and combinedwith the t-statistic.c)For intrusion detection,unsupervised Fuzzy C-means(FCM)clustering and supervised back-propagation NN are adopted.d)In addition and in order to enhance the suggested classifiers,FCM and NN are hybridized with the seven most known metaheuristic algorithms,including Genetic Algorithm(GA),Particle Swarm Optimization(PSO),Differential Evolution(DE),Cultural Algorithm(CA),Harmony Search(HS),Ant-Lion Optimizer(ALO)and black Hole(bH)*** metrics extracted from confusion matrices,such as accuracy,precision,sensitivity and F1-score are *** experimental result for the proposed intrusion detection,based on training and test CICIDS2017 datasets,indicated that PSO,GA and ALO-based NNs can achieve promising ***-NN produces a tested accuracy,global sensitivity and F1-score of 99.97%,99.95%and 99.96%,respectively,outperforming performance concluded in several related ***,the best-p

关键词： Classification neural networks Fuzzy C-means metaheuristic algorithm CICIDS2017 intrusion detection system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

LINEAR SEARCH FOR A bROWNIAN TARGET MOTION

引用

Acta Mathematica Scientia 2003年第3期23卷 321-327页

作者： A.b.el-Rayes Abdel-MoneimA.Mohamed Hamdy M.Abou Gabal Military Technical College CairoEgyptMilitary Technical CollegeCairoEgyptDepartment of MathematicsFaculty of ScienceTanta UniversityTantaEgypt

A target is assumed to move according to a brownian motion on the real line. The searcher starts from the origin and moves in the two directions from the starting point. The object is to detect the target. The purpose of this paper is to find the conditions under which the expected value of the first meeting time of the searcher and the target is finite, and to show the existence of a search plan which made this expected value minimum.

关键词： brownian process expected value linear search optimal search plan

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

On Hawking Radiation of 3D Rotating Hairy black Holes

引用

Chinese Physics Letters 2015年第10期32卷 14-16页

作者： belhaj A Chabab M el Moumni H. Masmar K. SedraM. b. Departement de Physique Faculte Polydisciplinaire Universite Sultan Moulay Slimane Beni Mellal Morocco High Energy Physics and Astrophysics Laboratory FSSM Cadi A yyad University Marrakesh Morocco Ddpartement de Physique LHESIR Faeulte des Sciences Universitd Ibn Tofail Kdnitra Morocco

We study the Hawking radiation of 3D rotating hairy black holes. Specifically, we compute the transition probability of bosonic and fermionic particles in such backgrounds. Then, we show that the transition probability is independent of the nature of the particle. It is observed that the charge of the scalar hairy b and the rotation parameter a control such a probability.

关键词： exp On Hawking Radiation of 3D Rotating Hairy black Holes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SOLUTION OF THE RAYLEIGH PRObLEM FOR A POWER-LAW NON-NEWTONIAN CONDUCTING FLUID VIA GROUP METHOD

引用

Applied Mathematics and Mechanics(English Edition) 2002年第6期23卷 639-646页

作者： Mina b.Abd-el-Malek Nagwa A.badran Hossam S.Hassan Department of Engineering Mathematics and Physics Faculty of Engineering Alexandria University Alexandria Egypt Department of basic and Applied Science Arab Academy for Science and Technology and Maritime Transport Alexandria Egypt

An investigation is made of the magnetic Rayleigh problem where a semi_infinite plate is given an impulsive motion and thereafter moves with constant velocity in a non_Newtonian power law fluid of infinite extent. The solution of this highly non_linear problem is obtained by means of the transformation group theoretic approach. The one_parameter group transformation reduces the number of independent variables by one and the governing partial differential equation with the boundary conditions reduce to an ordinary differential equation with the appropriate boundary conditions. Effect of the some parameters on the velocity u(y,t) has been studied and the results are plotted.

关键词： Rayleigh problem group method non_linearity conducting fluid non_Newtonian power law fluid

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：