检索结果-南通市图书馆

Influence of structural depth of laser-patterned steel surfaces on the solid lubricity of carbon nanoparticle coatings

引用

Friction 2023年第7期11卷 1276-1291页

作者： Timothy MACLUCAS Lukas DAUT Philipp GRÜTZMACHER maria agustina guitar Volker PRESSER Carsten GACHOT Sebastian SUAREZ Frank MÜCKLICH Chair of Functional Materials Saarland UniversitySaarbrücken 66123Germany Institute for Engineering Design and Product Development TU WienWien 1060Austria INM–Leibniz Institute for New Materials Saarbrücken 66123Germany Department of Materials Science&Engineering Saarland UniversitySaarbrücken 66123Germany Saarene-Saarland Center for Energy Materials and Sustainability Saarbrücken 66123Germany

Carbon nanoparticle coatings on laser-patterned stainless-steel surfaces present a solid lubrication system where the pattern's recessions act as lubricant-retaining *** study investigates the influence of the structural depth of line patterns coated with multi-walled carbon nanotubes(CNTs)and carbon onions(COs)on their respective potential to reduce friction and *** laser interference patterning(DLIP)with a pulse duration of 12 ps is used to create line patterns with three different structural depths at a periodicity of 3.5μm on AISI 304 steel ***,electrophoretic deposition(EPD)is applied to form homogeneous carbon nanoparticle coatings on the patterned *** ball-on-disc experiments are conducted on the as-described surfaces with an alumina counter body at a load of 100 *** results show that the shallower the coated structure,the lower its coefficient of friction(COF),regardless of the particle ***,with a minimum of just below 0.20,CNTs reach lower COF values than COs over most of the testing *** resulting wear tracks are characterized by scanning electron microscopy,transmission electron microscopy,and energy-dispersive X-ray *** friction testing,the CNTs remain in contact,and the immediate proximity,whereas the CO coating is largely *** of structural depth,no oxidation occurs on CNT-coated surfaces,whereas minor oxidation is detected on CO-coated wear tracks.

关键词： solid lubricant coatings carbon nanotubes carbon onions direct laser interference patterning(DLIP)surface structuring electrophoretic deposition(EPD)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Load dependent microstructural evolution in an as-cast 26%Cr high chromium cast iron during unlubricated sliding

引用

Friction 2022年第8期10卷 1258-1275页

作者： U.Pranav NAYAK Sebastian SUÁREZ Valentin PESNEL Frank MÜCKLICH María agustina guitar Department of Materials Science Saarland UniversitySaarbrücken 66123Germany Materials Engineering Center Saarland Saarbrücken 66123Germany Ecole Européenne d’ingénieurs en Génie des Matériaux Universitéde LorraineNancy 54000France

In the current study,an as-cast 26%Cr high chromium cast iron(HCCI)alloy was subjected to dry-sliding linear wear tests,under different *** loads were selected based on analytically computing the critical load(PC)i.e.,the load necessary to induce plastic *** PC was calculated to be 15 N and accordingly,a sub-critical load(5 N)and an over-critical load(20 N)were *** influence of increasing the load during the wear test was investigated in terms of the matrix microstructural behaviour and its ability to support the surrounding *** morphological aspects of the wear tracks,and the deformed matrix microstructure adjacent and underneath the track was analysed by confocal laser scanning microscope(CLSM)and scanning electron microscope(SEM),*** evidence of plastic deformation of the matrix was observed below *** the contrary,at loads equal to and higher than PC,the austenitic matrix plastically deformed as evidenced by the presence of slip *** backscattered diffraction(EBSD)measurements in terms of grain reference orientation deviation,and micro-Vickers hardness of the austenitic matrix indicated a deformation depth of about 40μm at the maximum applied load of 20 *** active wear mechanisms during sliding were a combination of both adhesive and abrasive wear,although increasing the load shifted the dominant mechanism towards *** was primarily attributable to the increased propensity for carbide cracking and fracturing,combined with the inability of the hardened austenitic matrix surface and sub-surface to adequately support the broken carbide ***,the shift in the dominant wear mechanism was also reflected in the wear volume and subsequently,the wear rate.

关键词： high chromium cast iron unlubricated sliding plastic deformation wear resistance carbide spallation matrix hardness

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nicotinic receptors modulate antitumor therapy response in triple negative breast cancer cells

引用

World Journal of Clinical Oncology 2022年第6期13卷 505-519页

作者： Alejandro Español Yamila Sanchez agustina Salem Jaqueline Obregon maria Elena Sales Laboratory of Immunopharmacology and Tumor Biology CEFYBO CONICET University of Buenos AiresBuenos Aires C1121ABGArgentina

BACKGROUND Triple negative breast cancer is more aggressive than other breast cancer subtypes and constitutes a public health problem worldwide since it has high morbidity and mortality due to the lack of defined therapeutic *** to chemotherapy complicates the course of patients’*** authors have highlighted the participation of nicotinic acetylcholine receptors(nAChR)in the modulation of conventional chemotherapy treatment in cancers of the ***,in breast cancer,less is known about the effect of nAChR activation by nicotine on chemotherapy treatment in smoking *** To investigate the effect of nicotine on paclitaxel treatment and the signaling pathways involved in human breast MDA-MB-231 tumor *** Cells were treated with paclitaxel alone or in combination with nicotine,administered for one or three 48-h *** effect of the addition of nicotine(at a concentration similar to that found in passive smokers’blood)on the treatment with paclitaxel(at a therapeutic concentration)was determined using the 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** signaling mediators involved in this effect were determined using selective *** also investigated nAChR expression,and ATP“binding cassette”G2 drug transporter(ABCG2)expression and its modulation by the different treatments with Western *** effect of the treatments on apoptosis induction was determined by flow cytometry using annexin-V and 7AAD *** Our results confirmed that treatment with paclitaxel reduced MDA-MB-231 cell viability in a concentration-dependent manner and that the presence of nicotine reversed the cytotoxic effect induced by paclitaxel by involving the expression of functionalα7 andα9 nAChRs in these *** action of nicotine on paclitaxel treatment was linked to modulation of the protein kinase C,mitogen-activated protein kinase,extracellular signal-regulated kinase,and NF-κB signaling pathways,

关键词： Breast cancer Paclitaxel Nicotinic acetylcholine receptors Drug therapy Signal transduction Drug transporter

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between Cancer and Environmental Exposure to Glyphosate

引用

International Journal of Clinical Medicine 2017年第2期8卷 73-85页

作者： Medardo Avila Vazquez Eduardo Maturano agustina Etchegoyen Flavia Silvina Difilippo Bryan Maclean Faculty of Medical Sciences National University of Cordoba Cordoba City Argentina Epidemiology Committee of Virology Institute Jose maria Vanella Faculty of Medical Sciences National University of Cordoba Cordoba City Argentina Center for Environmental Research Faculty of Exact Sciences National University of La Plata La Plata City Argentina

Background: Argentina, Brazil, Paraguay and Uruguay farm transgenic seeds glyphosate resistant. Argentina annually utilizes 240,000 tonnes of glyphosate in agriculture. A change in the profile of morbidity and mortality is perceived in agricultural areas;cancer seems to prevail. Monte Maíz is a typical argentine agricultural town with 8000 inhabitants;the Mayor and residents of Monte Maiz requested an environmental health study due to perceived increase in cancer frequencies. Methods: An exploratory ecological study was developed to assess the urban environmental contamination and the frequencies and distribution of cancer through an environmental analysis of pollution sources including measurements of pesticides in water, soil and grain dust, and a cross-sectional study of cancer patients that explore associations with different variables. Results: Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area. 650 tonnes are used annually in the region and manipulated inner town. We do not find other relevant sources of pollution. Cancer incidence, prevalence, and mortality are between two and three times higher than the reference values (Globocan 2012, WHO) for the entire nation (706/100,000 persons vs. 217/100,000;2123/100,000 persons vs. 883.82/100,000 and 383/100,000 persons vs. 115.13/100,000, respectively). Conclusion: This study detects high glyphosate pollution in association with increased frequencies of cancer in a typical argentine agricultural village, and by design, cannot make claims of causality. Other study designs are required, but if we corroborate the concrescence of high exposure to glyphosate and cancer.

关键词： Glyphosate Pesticides Cancer Environmental Health Environmental Exposure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Environmental Exposure to Glyphosate and Reproductive Health Impacts in Agricultural Population of Argentina

引用

Journal of Environmental Protection 2018年第3期9卷 241-253页

作者： Medardo Avila-Vazquez Flavia S. Difilippo Bryan Mac Lean Eduardo Maturano agustina Etchegoyen Chair of Pediatric Clinic Faculty of Medical Sciences National University of Cordoba Cordoba Argentina Epidemiology Committee of Virology Institute Jose maria Vanella Faculty of Medical Sciences National University of Cordo-ba Cordoba Argentina Center for Environmental Research Faculty of Exact Sciences National University of La Plata La Plata Argentina

Argentina annually utilizes 240,000 tones of glyphosate in industrial agriculture and a change in the profile of morbidity is perceived for physicians of agricultural areas;now reproductive disorders seem to prevail. The objective of this study is to determine concurrence of glyphosate exposure and reproductive disorders in a typical argentine agricultural town (Monte Maíz). An ecological study was developed with an environmental analysis of pollution sources including measurements of glyphosate and other pesticides and a cross-sectional study of spontaneous abortions and congenital abnormalities prevalence. Glyphosate was detected in soil and grain dust and was found to be at an even higher concentration in the village soil than in the rural area;650 tonnes of glyphosate are used annually in the region and manipulated inner town contaminating the soil and dust in suspension of the town creating an burden of environmental exposure to glyphosate of 79 kg per person per year. We do not find other relevant sources of pollution. The spontaneous abortion and congenital abnormalities rates are three and two times higher than the national average reported by the national health (10% vs. 3% and 3% - 4.3% vs 1.4% respectively). Our study verified high environmental exposure to glyphosate in association with increased frequencies of reproductive disorders (spontaneous abortion and congenital abnormalities) in argentine agricultural village, but is unable to make assertions cause-effect. Further studies are required with designs for such purposes.

关键词： Glyphosate Spontaneous Abortions Congenital Abnormalities Environmental Exposure Environmental Health

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：