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Muscle force and movement variability before and after total knee arthroplasty: A review

World Journal of Orthopedics 2014年第2期5卷 69-79页

作者： Jessica W Smith Jesse C Christensen Robin l marcus Paul C laStayo Department of Bioengineering University of Utah Salt Lake City UT 84108-1290 United States Department of Physical Therapy University of Utah Salt Lake City UT 84108-1290 United States Department of Orthopedics University of Utah Salt Lake City UT 84108-1290 United States Department of Exercise and Sport Science University of Utah Salt Lake City UT 84108-1290 United States

Variability in muscle force output and movement variability are important aspects of identifying individuals with mobility deficits, central nervous system impairments, and future risk of falling. This has been investigated in elderly healthy and impaired adults, as well as in adults with osteoarthritis(OA), but the question of whether the same correlations also apply to those who have undergone a surgical intervention such as total knee arthroplasty(TKA) is still being investigated. While there is a growing body of literature identifying potential rehabilitation targets for individuals who have undergone TKA, it is important to first understand the underlying post-operative impairments to more efficiently target functional deficits that may lead to improvedlong-term outcomes. The purpose of this article is to review the potential role of muscle force output and movement variability in TKA recipients. The narrative review relies on existing literature in elderly healthy and impaired individuals, as well as in those with OA before and following TKA. The variables that may predict longterm functional abilities and deficits are discussed in the context of existing literature in healthy older adults and older adults with OA and following TKA, as well as the role future research in this field may play in providing evidence-based data for improved rehabilitation targets.

关键词： Osteoarthritis Elderly Total knee arthroplasty Movement variability

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3D Nonlinear Numerical Simulation of Intact and Debonded Reinforced Concrete Beams

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Journal of Southwest Jiaotong University(English Edition) 2004年第2期12卷 173-177页

作者：陈权 marcus l. School of Computer and Communication Engineering Southwest Jiaotong University Department of Civil and Environment University of Southampton

To study the behaviour of reinforced concrete (RC) structures with sections of concrete removed and the reinforcement exposed, 3D nonlinear numerical analysis was performed upon both intact and debonded RC beams by using finite element techniques. The deformational characteristics and the ultimate loads were obtained through numerical models, as well as crack and stress distributions. The failure modes can also be deduced from computational results. Compared with intact beams, the normal assumptions of plane section behaviour is not hold true and the patterns of stress and strain are different in debonded RC beams. The numerical results show good consistency with experimental data. This kind of numerical simulation is a supplement to existing codes.

关键词： Finite element Reinforced concrete Nonlinear Ultimate load

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多环芳烃的慢性暴露对人体皮肤微生物菌群的影响

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中华皮肤科杂志 2021年第4期54卷 368-369页

作者： marcus l Xinzhao T Philippe B 不详

多环芳烃(PAHS)是一类可通过吸入、食入和经皮吸收的方式进入体内和血液循环中的有机污染物,常常存在于大气的颗粒物中。虽然已知皮肤对PAHs的慢性暴露可能与皮肤的过早老化、色素沉着、痤疮和皮肤肿瘤有关,但我们对其确切机制仍缺乏了... 详细信息

多环芳烃(PAHS)是一类可通过吸入、食入和经皮吸收的方式进入体内和血液循环中的有机污染物,常常存在于大气的颗粒物中。虽然已知皮肤对PAHs的慢性暴露可能与皮肤的过早老化、色素沉着、痤疮和皮肤肿瘤有关,但我们对其确切机制仍缺乏了解。与此同时,随着皮肤表面微生物菌群对宿主皮肤健康影响的研究不断深人,有研究证实皮肤共生菌群可降解不同的PAHs及与其相关的外源性成分。由于PAHs暴露与皮肤微生态之间可能存在潜在关联,因此有必要进一步探索PAHs对皮肤微生物菌群的影响机制。

关键词：多环芳烃有机污染物微生物菌群皮肤肿瘤皮肤健康血液循环经皮吸收色素沉着

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儿童阻塞性睡眠呼吸暂停综合征手术干预后的相关问题

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中国循证儿科杂志 2016年第1期11卷 1-2页

作者： Carole l.marcus 申昆玲许志飞美国宾夕法尼亚大学费城儿童医院呼吸科首都医科大学附属北京儿童医院呼吸科

申昆玲教授很高兴在＂北京国际儿科发展论坛暨呼吸分论坛＂中与美国宾夕法尼亚大学费城儿童医院呼吸科睡眠中心的负责人Carole ***教授相聚,值此荣幸地邀请marcus教授参加儿童阻塞性睡眠呼吸暂停综合征（OSAS）手术干预后的相关问题的... 详细信息

申昆玲教授很高兴在＂北京国际儿科发展论坛暨呼吸分论坛＂中与美国宾夕法尼亚大学费城儿童医院呼吸科睡眠中心的负责人Carole ***教授相聚,值此荣幸地邀请marcus教授参加儿童阻塞性睡眠呼吸暂停综合征（OSAS）手术干预后的相关问题的专家对谈录。OSAS在儿童中较为常见,发病率3%~5%,可引起儿童生长发育落后、心血管和神经认知问题。腺样体、扁桃体肥大是儿童OSAS的主要病因,腺样体、扁桃体切除术是儿童OSAS的一线治疗方法。手术是有创的治疗方法,

关键词：手术干预腺样体费城儿童医院扁桃体肥大神经认知扁桃体切除术睡眠呼吸障碍呼吸科阻塞性呼吸暂停认知功能

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Robotic-assisted laparoscopic partial nephrectomy: A comparison of approaches to the posterior renal mass

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World Journal of Clinical Urology 2016年第1期5卷 60-65页

作者： Jessica J Wetterlin Robert H Blackwell Sarah Capodice Stephanie Kliethermes marcus l Quek Gopal N Gupta Department of Urology Loyola University Medical Center Stritch School of Medicine Loyola University Medical Center Department of Public Health Loyola University Medical Center

AIM: To evaluate outcomes of robotic-assisted laparoscopic partial nephrectomy performed for posterior renal tumors via a transperitoneal or retroperitoneal ***: Retrospective review was performed for patients who underwent robotic-assisted laparoscopic partial nephrectomy(RAlPN) for a posterior renal tumor between 2009-2015. Patient demographic characteristics, operative factors, pathology, oncologic outcomes, renal function, and tumor complexity were obtained. Radius of the tumor, exophytic/endophytic properties of the tumor, nearness of tumor to the collecting system, anterior/posterior position, location relative to the polar line(RENAl) nephrometry scores were calculated. nephrometry scores were calculated. The operative approach was determined by the primary surgeon. RESUlTS: A total of 91 patients were identified who underwent RAlPN for a posterior renal tumor. Fifty-four procedures were performed via the retroperitoneal(RP) approach, and 37 via the transperitoneal(TP) approach. There were no significant differences in patient factors(race, sex, age and body mass index), RENAl nephrometry scores, tumor size, conversion rates, or margin status. Among procedures performed on-clamp, therewas no significant difference in warm ischemia times. Total operative time(180.7 min for RP vs 227.8 min for TP, P le time(126.9 min for RP vs 164.3 min for TP, P lood loss(32.5 m l for RP vs 150 ml for TP, P ly lower via the RP approach. Off-clamp RAlPN was performed for 31(57.4%) of RP procedures vs 9(24.3%) of TP procedures. Oncologic and renal functional outcomes were ***: The RP approach to RAlPN for posterior renal tumors is superior with regard to operative time and blood loss and the ability to be performed off-clamp.

关键词： Retroperitoneal Transperitoneal Roboticassisted laparoscopic partial nephrectomy Posterior renal masses

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Perioperative outcomes and survival of radical cystectomy as a function of body mass index

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World Journal of Clinical Urology 2016年第1期5卷 53-59页

作者： Bethany K Burge Robert H Blackwell Andrew Wilson Robert C Flanigan Gopal N Gupta marcus l Quek Department of Urology Loyola University Medical Center Stritch School of Medicine Loyola University

AIM: To evaluate the perioperative and long term outcomes of cystectomy in obese ***: This is a retrospective review of 580 patients for whom radical cystectomy(RC) was performed for primary urothelial bladder cancer between November 1996-April 2013 at a single institution. Body mass index(BMI) was available for 424 patients who were categorized as underweight(l(18.5-24.9), overweight(25.0-29.9), and obese(≥ 30). Baseline demographics, perioperative outcomes, and survival were assessed. Overall survival(OS) and disease specific survival(DSS) was estimated by Kaplan-Meier method. Medians were compared using the Mann-Whitney U Test. Categorical variables were compared using the χ2 test. A P-value of lly significant. Statistical analyses were performed using the Software Package for the Social Sciences(SPSS), Version 20(International Business Machines SPSS, Chicago, Il, United States). RESUlTS: The median age of all patients was 69 years(inter-quartile range 60-75) and median followup was 23.4 mo(8.7-55.1). Patients were characterized as underweight [9,(2.1%)], normal [113,(26.7%)],overweight [160,(37.8%)], or obese [142,(33.5%)]. Estimated blood loss during RC was higher in the obese group(800 m l) as compared to the normal weight group(500 m l). However, need for transfusion(47.7% vs 52.1%), number of lymph nodes resected(32 vs 30), length of stay(9 d vs 8 d), and 30-d readmission(29.7% vs 25.2%) between obese and normal BMI patients were similar. Obese patients underwent ileal neobladder diversion in 42% of cases, compared to 24% of normal BMI patients(0.003). Normal BMI and obese patients had comparable urinary incontinence(21.4% vs 25.6%, P = 0.343), and need for intermittent catheterization(14.3% vs 5.2%, P = 0.685) at 2 years follow-up. Overall survival was better in obese compared to normal BMI patients on univariate analysis, with median survival of 67 mo vs 37 mo, respectively(P = 0.031). Disease spec

关键词： Urinary bladder neoplasms Body mass index Obesity Cystectomy Underweight

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图书馆步入摩登时代

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英语学习 2002年第8期 44-45页

作者：曾敬 David l. marcus

在网络资源极其丰富的今天,有人预测图书馆将成为书籍的坟墓。而事实正好相反,恰恰是互联网的优势和全新的管理方式吸引越来越多的人来到图书馆,把这里变为都市生活的又一个"好去处"。

关键词：图书馆都市生活摩登时代俄勒冈州

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湿空气环境对铝合金da/dN和J1c的影响

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东北大学学报(自然科学版) 1983年第1期 89-94+130页

作者：曾梅光 ,H.l.marcus 美国得克萨斯大学材料科学与工程系教授

湿空气促进铝合金疲劳裂纹生长和增加合金的脆性。对于不同热处理的合金,影响也是不同的。腐蚀疲劳降低铝合金的断裂韧性Jc,而Jc降低的百分数随真空和湿空气中da/dN的增加而增加。

关键词：铝合金湿空气疲劳裂纹断裂韧性轻有色金属合金破断韧性力学强度 J1c da/dN

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单试样测定铝合金JIc的新方法

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东北大学学报(自然科学版) 1983年第4期 5-11+129-130+154页

作者：曾梅光,H.l.marcus 东北工学院金属物理教研室美国得克萨斯大学

本文提出了一个根据载荷-载荷点位移曲线上的柔度变化测定铝合金JIC的单试样法和计算J积分公式: 实验结果表明:使用这种方法测得的JIC值与用多试样法测得结果符合。使用上述公式计算的JIC值和用J=（1+α）/（1+α2）-2A/B（w-α）计算... 详细信息

本文提出了一个根据载荷-载荷点位移曲线上的柔度变化测定铝合金JIC的单试样法和计算J积分公式: 实验结果表明:使用这种方法测得的JIC值与用多试样法测得结果符合。使用上述公式计算的JIC值和用J=（1+α）/（1+α2）-2A/B（w-α）计算的结果相一致。

关键词：多试样法位移曲线裂纹扩展量 Ic 铝合金轻有色金属合金单试样法柔度

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Adjuvant radiotherapy for pathologically advanced prostate cancer improves biochemical recurrence free survival compared to salvage radiotherapy

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World Journal of Clinical Urology 2016年第1期5卷 45-52页

作者： Robert H Blackwell William Gange Alexander M Kandabarow Matthew M Harkenrider Gopal N Gupta marcus l Quek Robert C Flanigan Department of Urology Loyola University Medical Center Stritch School of Medicine Loyola University Chicago Department of Radiation Oncology Loyola University Medical Center

AIM: To evaluate the long-term outcomes of patients receiving adjuvant and salvage radiotherapy following prostatectomy with adverse pathologic features and an undetectable prostate specific antigen(PSA).METHODS: A retrospective review was performed of patients who received post-prostatectomy radiation at loyola University Medical Center between 1992 and 2013. Adverse pathologic features(Gleason score ≥ 8, seminal vesicle invasion, extracapsular extension, pathologic T4 disease, and/or positive surgical margins) and an undetectable PSA following prostatectomy were required for inclusion. Adjuvant patients received therapy with an undetectable PSA, salvage patients following biochemical recurrence(BCR). Post-radiation BCR, overall survival, bone metastases, and initiation of hormonal therapy were assessed. Kaplan-Meier time-to-event analyses and stepwise Cox proportional hazards regression(HR) were performed. RESUlTS: Post-prostatectomy patients(n = 134) received either adjuvant(n = 47) or salvage(n = 87) radiation. Median age at radiotherapy(RT) was 63 years, and median follow-up was 53 mo. Five-year post-radiation BCR-free survival was 78% for adjuvant vs 50% salvage radiotherapy(SRT)(logrank P = 0.001). Patients with radiation administered following a detectable PSA had an increased risk of BCR compared to undetectable: PSA > 0.0-0.2: HR = 4.1(95%CI: 1.5-11.2; P = 0.005); PSA > 0.2-1.0: HR = 4.4(95%CI: 1.6-11.9; P = 0.003); and PSA > 1.0: HR = 52(95%CI: 12.9-210; P le difference in rates of overall survival, bone metastases or utilization of hormonal therapy between adjuvant and SRT patients. CONClUSION: Adjuvant RT improves BCR-free survival compared to SRT in patients with adverse pathologic features and an undetectable post-prostatectomy PSA.

关键词： Radiotherapy Adjuvant Radiotherapy Salvage therapy Recurrence Prostatic neoplasms

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