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Limited cross-variant neutralization after primary Omicron infection:consideration for a variant-containing booster

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3174-3176页

作者： Harold marcotte Lennart Hammarstrom Qiang Pan-Hammarstrom Department of Biosciences and Nutrition Karolinska Institutet14157 HuddingeSweden

In a recent study published in Nature,Suryawanshi et *** that primary Omicron infection only elicits a mild humoral immune response and limited cross-variant neutralization in non-vaccinated individuals.1On the other hand,vaccinated individuals developed high neutralizing antibody titers against all variants of concern(VOCs)following breakthrough Omicron ***,Omicron infection can enhance existing immunity induced by vaccination but may not prevent reinfection by other VOCs in non-vaccinated individuals.

关键词： breakthrough immunity Omi

The formation of orthogonal joint systems and cuboidal blocks:New insights gained from flat-lying limestone beds in the region of Havre-Saint-Pierre(Quebec,Canada)

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第12期15卷 3079-3093页

作者： Shaocheng Ji Yvéric Rousseau Denis marcotte Noah John Phillips Département des Génies Civil Géologique et des MinesÉcole Polytechnique de MontréalMontréalQuébecH3C 3A7Canada Department of Geology Lakehead UniversityThunder BayOntarioP7B 5E1Canada

Vertical orthogonal joints are a common feature in shallow crustal *** are several competing theories for their formation despite the *** examined the exceptional exposures of orthogonal joints in flat-lying Ordovician limestone beds from the Havre-Saint-Pierre Region in Quebec,Canada(north shore of Saint-Lawrence River)to test conceptual models of joint formation in a natural *** the region,the spacing of cross-joints is consistently larger than the spacing of systematic joints by a factor of 1.5 *** joint-spacing-to-bed-thickness ratios(s/t)are much larger in these beds(s/t=4.3 for systematic joints,and 6.4 for cross-joints)than those in higher strained strata along the south shore of the Saint-Lawrence River(s/t=1),highlighting the effect of tectonic strain in decreasing fracture spacing and block *** high values of s/t indicate that cross-joint formation was unlikely caused by a switch from compression to tension once a critical s/t ratio for systematic joints was reached(as hypothesized in previous studies).We proposed a new model for the formation of orthogonal joint systems where the principal stress axes locally switch during the formation of systematic *** presence of ladder-shaped orthogonal joints suggests a state of effective stress withσ_(1)^(∗)≫0>σ_(2)^(∗)>σ_(3)^(∗)and whereσ_(2)^(∗)-σ_(3)^(∗)is within the range of fracture strength variability at the time of *** research provides a new mechanical model for the formation of orthogonal joint systems and cuboidal blocks.

关键词： Plato's cuboids Orthogonal joints Fracture spacing Limestone Layered rock mechanics Appalachian geology

Production of liquid bio-fuel from catalytic de-oxygenation:Pyrolysis of beech wood and flax shives

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燃料化学学报 2019年第2期47卷 153-166页

作者： Chetna Mohabeer Luis Reyes Lokmane Abdelouahed Stéphane marcotte Jean-Christophe Buvat Lucette Tidahy Edmond Abi-Aad Bechara Taouk Normandie Univ INSA Rouen NormandieUNIROUENLaboratoire de Sécurité des Procédés Chimiques Normandie Univ INSA Rouen NormandieUNIROUEN Université du Littoral Cte d'Opale Unité de Chimie Environnementale et Interactions sur le Vivant

This study presents a detailed analysis of the catalytic de-oxygenation of the liquid and gaseous pyrolytic products of two biomasses (beech wood and flax shives) using different catalysts (commercial HZSM-5 and H-Y,and lab-synthesised Fe-HZSM-5,Fe-H-Y,Pt/Al2O3 and CoMo/Al2O3). The experiments were all conducted in a semi-batch reactor under the same operating conditions for all feed materials. BET specific surface area,BJH pore size distribution and FT-IR technologies have been used to characterise the catalysts,while gas chromatography-mass spectrometry (GC-MS),flame ionisation detection (GC-FID) and thermal conductivity detection (GC-TCD) were used to examine the liquid and gaseous pyrolytic products. It was firstly seen that at higher catalyst-to-biomass ratios of 4∶1,de-oxygenation efficiency did not experience any further significant improvement. FeHZSM-5 was deemed to be the most efficient of the catalysts utilised as it helped reach the lowest oxygen contents in the bio-oils samples and the second best was HZSM-5. It was also found that HZSM-5 and H-Y tended to privilege the decarbonylation route(production of CO),whilst their iron-modified counterparts favoured the decarboxylation one (production of CO2) for both biomasses studied. It was then seen that the major bio-oil components (carboxylic acids) underwent almost complete conversion under catalytic treatment to produce mostly unoxygenated aromatic compounds,phenols and gases like CO and CO2. Finally,phenols were seen to be the family most significantly formed from the actions of all catalysts.

关键词： pyrolysis biomass catalytic treatment de-oxygenation bio-oil upgrading

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On the Ladder

小学生时代（大嘴英语） 2021年第3期 40-41页

作者： Kathleen marcotte 不详

美好的童年怎么能少得了一间可爱的树屋呢?和好朋友一起,在珍藏着很多秘密的树屋里玩耍,那会是怎样的一种快乐呀!

关键词： Ladder 快乐 On

WheatNet： a Genome-Scale Functional Network for Hexaploid Bread Wheat, Triticum aestivum

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Molecular Plant 2017年第8期10卷 1133-1136页

作者： Tak Lee Sohyun Hwang Chan Yeong Kim Hongseok Shim Hyojin Kim Pamela C. Ronald EdwardM. marcotte Insuk Lee Department of Biotechnology College of Life Science and Biotechnology Yonsei University Seou1120-749 Korea Center for Systems and Synthetic Biology Institute for Cellular and Molecular Biology University of Texas at Austin Austin TX 78712 USA Department of Biomedical Science College of Life Science CHA University Seongnam-si 13496 Korea Department of Plant Pathology University of California Davis CA 95616 USA Joint Bioenergy Institute Emeryville CA 94608 USA The Genome Center University of California Davis CA 95616 USA Department of Molecular Bioseiences University of Texas at Austin Austin TX 78712 USA

Dear Editor Gene networks provide a system-level overview of genetic organizations and enable the dissection of functional modules underlying complex traits. Integration of diverse genomics data based on the Bayesian statistics framework has been successfully applied to the construction of genome-scale functional networks for major crop species such as rice （Lee et al., 2011）, soybean （Kim et al., 2017）, and tomato （Kim et al.,

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渗透脱水蓝莓流化床干燥工艺的研究

食品与发酵工业 2006年第2期32卷 50-52页

作者：董全 Michèle marcotte 陈宗道西南大学食品科学学院加拿大食品研究与开发中心

经渗透脱水处理的蓝莓在流化床中用5种不同的干燥温度(50、60、70、80、90℃)进行干燥,结果显示, 干燥温度影响物料的水分散失,水分散失率随温度的提高而增加。随着干燥处理的进行水分含量和水分活度都呈下降趋势,且温度越高,两者下降... 详细信息

经渗透脱水处理的蓝莓在流化床中用5种不同的干燥温度(50、60、70、80、90℃)进行干燥,结果显示, 干燥温度影响物料的水分散失,水分散失率随温度的提高而增加。随着干燥处理的进行水分含量和水分活度都呈下降趋势,且温度越高,两者下降越多。根据费克第二不稳定扩散法则,计算出不同温度下的有效水分扩散率 (D_(eff))分别为(0．753 2～3．673 7)×10^(-10)m^2/s。在干燥脱水处理过程中 D_(eff)随处理温度升高而增加。

关键词：渗透脱水蓝莓有效水分扩散率流化床干燥

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蓝莓渗透脱水的研究

食品与发酵工业 2004年第7期30卷 1-5页

作者：董全 Michèle marcotte 陈宗道西南农业大学食品科学学院 Food Research and Development Centre Agriculture and Agri-Food CanadaSaint HyacintheQuebecCanada

在不同的渗透温度 ( 4 5～ 65℃ )条件下 ,高果糖浆和蔗糖的有效水分扩散率 (Dm)分别为( 4 90 60～ 5 2 3 66)× 1 0 - 10 m2 /s和 ( 3 5 5 1 8～ 4 0 1 0 9)× 1 0 - 10 m2 /s,有效固形扩散率 (Ds)分别为( 2 7740～ 3 691 5 )× 1... 详细信息

在不同的渗透温度 ( 4 5～ 65℃ )条件下 ,高果糖浆和蔗糖的有效水分扩散率 (Dm)分别为( 4 90 60～ 5 2 3 66)× 1 0 - 10 m2 /s和 ( 3 5 5 1 8～ 4 0 1 0 9)× 1 0 - 10 m2 /s,有效固形扩散率 (Ds)分别为( 2 7740～ 3 691 5 )× 1 0 - 10 m2 /s和 ( 1 3 1 63～ 2 691 5 )× 1 0 - 10 m2 /s的规律。在渗透脱水处理过程中Dm 和Ds 随处理温度升高而增加。经高果糖浆 ( 70°Brix)渗透脱水的蓝莓的平均体积比随温度升高而稍微下降。

关键词：蓝莓渗透脱水高果糖浆蔗糖有效水分扩散率有效固体扩散率

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真空、脉冲真空和常压下蓝莓渗透脱水的研究

食品科学 2007年第9期28卷 92-95页

作者：董全 Michèle marcotte 陈宗道西南大学食品科学学院重庆400716 Food Research and Development Centre Agriculture and Agri-Food CanadaSaint-HyacintheQuebecCanada

研究了真空渗透脱水、脉冲真空渗透脱水和常压渗透脱水下蓝莓水分含量和水分活度的变化规律,结果表明:真空渗透脱水时,蓝莓的水分含量和水分活度降低得最快。真空渗透脱水、脉冲真空渗透脱水、常压下渗透脱水蓝莓的有效水分扩散率分别为... 详细信息

研究了真空渗透脱水、脉冲真空渗透脱水和常压渗透脱水下蓝莓水分含量和水分活度的变化规律,结果表明:真空渗透脱水时,蓝莓的水分含量和水分活度降低得最快。真空渗透脱水、脉冲真空渗透脱水、常压下渗透脱水蓝莓的有效水分扩散率分别为1.6777×10-9、1.3629×10-9、0.5679×10-9m2/s。真空渗透脱水、脉冲真空渗透脱水、常压下渗透脱水的有效固性物扩散率分别为9.1705×10-10、6.3919×10-10、5.1007×10-10m2/s。

关键词：蓝莓真空渗透脱水脉冲真空渗透脱水常压下渗透脱水

Management of adults with coarctation of aorta

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World Journal of Cardiology 2020年第5期12卷 167-191页

作者： Pradyumna Agasthi Sai Harika Pujari Andrew Tseng Joseph N Graziano Francois marcotte David Majdalany Farouk Mookadam Donald J Hagler Reza Arsanjani Department of Cardiovascular Diseases Mayo ClinicScottsdaleAZ 85259United States Department of Cardiovascular Diseases Mayo ClinicRochesterMN 55905United States Division of Cardiology Phoenix Children's HospitalChildren's Heart CenterPhoenixAZ 85016United States

Coarctation of the aorta(CoA)is a relatively common congenital cardiac defect often causing few symptoms and therefore can be challenging to *** hallmark finding on physical examination is upper extremity hypertension,and for this reason,CoA should be considered in any young hypertensive patient,justifying measurement of lower extremity blood pressure at least once in these *** presence of a significant pressure gradient between the arms and legs is highly suggestive of the *** diagnosis and treatment are important as long-term data consistently demonstrate that patients with CoA have a reduced life expectancy and increased risk of cardiovascular *** repair has traditionally been the mainstay of therapy for correction,although advances in endovascular technology with covered stents or stent grafts permit nonsurgical approaches for the management of older children and adults with native CoA and *** hypertension and vascular dysfunction can lead to an increased risk of coronary disease,which,remains the greatest cause of long-term ***,blood pressure control and periodic reassessment with transthoracic echocardiography and threedimensional imaging(computed tomography or cardiac magnetic resonance)for should be performed regularly as cardiovascular complications may occur decades after the intervention.

关键词： Coarctation of aorta Cardiac surgery Cardiac catheterization Balloon angioplasty Stents