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Journal of Sport and Health Science 2019年第6期8卷 579-584页

作者： Pedro ALatorre-Román Felipe García-Pinillos Víctor M.Soto-Hermoso marcos munoz-jiménez Department of Didactics of Corporal Expression University of JaénJaen 23071Spain Department of Sports Sciences University of GranadaGranada 18071Spain

Purpose:The purpose of this study was to determine the effects of 12 weeks of barefoot running on foot strike patterns,inversion-eversion and foot rotation in long-distance ***:Thirty-one endurance runners with no experience in barefoot running were randomized into a control group and an experimental group who received barefoot *** pre-test and post-test,all subjects ran at low and high self-selected speeds on a *** were collected by systematic observation of lateral and back recordings at 240 ***:McNemar’s test indicated significant changes(p <0.05) in the experimental group at both high and low speed running in foot strike patterns,reducing the percentage of high rearfoot strikers and increasing the number of midfoot strikers.A significant increase(p <0.05) of external rotation of the foot and a decrease of inversion occurred at comfortable speed in the experimental ***:Twelve weeks of barefoot running,applied progressively,causes significant changes in foot strike pattern with a tendency toward midfoot or forefoot strikes,regardless of running speed and significant changes in foot rotation at low speed,while the inversion was reduced in left foot at low speed with a tendency toward centered strike.

关键词： Endurance Footwear Kinematics Training Unshod

Investigation of pore geometry influence on fluid flow in heterogeneous porous media:A pore-scale study

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Energy Geoscience 2024年第1期5卷 72-88页

作者： Ramin Soltanmohammadi Shohreh Iraji Tales Rodrigues de Almeida Mateus Basso Eddy Ruidiaz munoz Alexandre Campane Vidal Ingram School of Engineering Texas State UniversitySan MarcosTX78666USA Department of Mechanical Engineering(FEM) State University of Campinas(UNICAMP)CampinasSP13083-855Brazil Department of Geology and Natural Resources Geosciences Institute(IG)State University of Campinas(UNICAMP)CampinasSP13083-855Brazil Center of Energy and Petroleum Study(CEPETRO) State University of Campinas(UNICAMP)CampinasSP13083-855Brazil

Brazilian pre-salt reservoirs are renowned for their intricate pore networks and vuggy nature,posing significant challenges in modeling and simulating fluid flow within these carbonate *** possessing excellent petrophysical properties,such as high porosity and permeability,these reservoirs typically exhibit a notably low recovery factor,sometimes falling below 10%.Previous research has indicated that various enhanced oil recovery(EOR)methods,such as water alternating gas(WAG),can substantially augment the recovery factor in pre-salt reservoirs,resulting in improvements of up to 20%.Nevertheless,the fluid flow mechanism within Brazilian carbonate reservoirs,characterized by complex pore geometry,remains *** study examines the behavior of fluid flow in a similar heterogeneous porous material,utilizing a plug sample obtained from a vugular segment of a Brazilian stromatolite outcrop,known to share analogies with certain pre-salt *** conducted single-phase and multi-phase core flooding experiments,complemented by medical-CT scanning,to generate flow streamlines and evaluate the efficiency of water ***,micro-CT scanning of the core sample was performed,and two cross-sections from horizontal and vertical plates were *** cross-sections were then employed as geometries in a numerical simulator,enabling us to investigate the impact of pore geometry on fluid *** of the pore-scale modeling and experimental data unveiled that the presence of dead-end pores and vugs results in a significant portion of the fluid remaining stagnant within these ***,the injected fluid exhibits channeling-like behavior,leading to rapid breakthrough and low areal swept ***,the numerical simulation results demonstrated that,irrespective of the size of the dead-end regions,the pressure variation within the dead-end vugs and pores is *** the stromatolite's favorable petrophysica

关键词： Pore-scale modeling Pore geometry Flow streamlines Computational modeling Digital rock analysis

利用采光井进行建筑通风的新型应用模型:基于案例研究评估的建议（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2018年第10期19卷 796-810页

作者： Miguel Angel PADILLA-marcos Alberto MEISS Jesus FEIJO-munoz Research Group of Architecture&Energy Universidad de ValladolidValladolid 47014Spain

目的:1.探究如何在有限的室外空间下简便地计算换气质量;2.建立利用采光井进行建筑通风的应用模型。创新点:1.案例研究评估的成熟方法论应用;2.得到采光井对室内空气通风促进度的速算图表。方法:1.采用风洞分析的两步确认法;2.对实际采... 详细信息

目的:1.探究如何在有限的室外空间下简便地计算换气质量;2.建立利用采光井进行建筑通风的应用模型。创新点:1.案例研究评估的成熟方法论应用;2.得到采光井对室内空气通风促进度的速算图表。方法:1.采用风洞分析的两步确认法;2.对实际采光井模型进行计算流体动力学应用。结论:1.高长比小于3的采光井表现出了不错的换气能力;2.对空气质量要求更高的居住空间(如卧室和起居室)而言,室内通风口必须被设在高度低于24米的采光井的上半部分或者其他采光井中距离顶部12米以内的位置。

关键词：室外空气质量采光井自然通风计算流体动力学换气效率

Electrocardiographic markers of cardiac resynchronization therapy response:delayed time to intrinsicoid deflection onset in lateral leads

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Journal of Geriatric Cardiology 2022年第1期19卷 21-30页

作者： Rubén KA Tapia-Orihuela S Michael Gharacholou Samuel J Asirvatham Freddy Del-Carpio munoz Department of Medicine Universidad Nacional Mayor de San MarcosFacultad de Medicina de San FernandoLimaPeru Department of Cardiovascular Diseases Mayo ClinicJacksonvilleFLUSA Department of Cardiovascular Diseases Mayo ClinicRochesterMNUSA

Cardiac resynchronization therapy(CRT)has emerged as an important intervention for patients with heart failure(HF)with reduced ejection fraction and delayed ventricular *** these patients,CRT has demonstrated to improve quality of life,promote reverse left ventricular(LV)remodeling,reduce HF hospitalizations,and extend ***,despite advancements in our understanding of CRT,a significant number of patients do not respond to this *** invasive and non-invasive parameters have been assessed to predict response to CRT,but the electrocardiogram(ECG)has remained as the prevailing screening method albeit with ***,an accurate,simple,and reproducible ECG marker or set of markers would dramatically overcome the current *** describe the clinical utility of an old ECG parameter that can estimate ventricular activation delay:the onset to intrinsicoid deflection(ID).Based on the concept of direct measurement of ventricular activation time(intrinsic deflection onset),time to ID onset measures on the surface ECG the time that the electrical activation time takes to reach the area subtended by the corresponding surface ECG *** on this principle,the time to ID on the lateral leads can estimate the delay activation to the lateral LV wall and can be used as a predictor for CRT response,particularly in patients with non-specific intraventricular conduction delay or in patients with left bundle branch block and QRS<150 *** aim of this review is to present the current evidence and potential use of this ECG parameter to estimate LV activation and predict CRT response.

关键词： deflection intrinsic synchronization

Transvaginal Approach for Nongynecologic Intraperitoneal Procedures

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International Journal of Clinical Medicine 2014年第21期5卷 1417-1429页

作者： Jose F.Noguera Gonzalo Martin Jose M.munoz Antonio Melero Raul Sanchez Javier Valdivia marcos Bruna Antonio Salvador Cristobal Zaragoza Minimally Invasive Therapies Unit Consorcio Hospital General Universitario de ValenciaValenciaSpain Department of Surgery Hospital Son LlatzerPalmaSpain Department of Surgery Consorcio Hospital General Universitario de ValenciaValenciaSpain Department of Surgery Hospital Virgen de las NievesGranadaSpain

The minimally invasive surgery through natural orifices has revolutionized the laparoscopic surgery for abdominal procedures. The use of the vaginal approach is not new for gynecologists but it is a new concept for the non-gynecological laparoscopic surgeons. The use of this new approach has been used to perform some procedures and to extract specimens after a laparoscopic surgery, but we don’t know exactly the number of procedures performed until today. There are few papers with clinical experience and a lot of philosophical papers about NOTES. Our aim is to know how and how often we are using this new approach for non-gynecological abdominal minimally invasive procedures. With the revision of the PubMed publications we obtained a total of 268 articles, of which 125 were included in the analysis (46.64%). Cholecystectomy was the procedure more usually performed: there is a large clinical experience with a total of 2432 transvaginal cholecystectomies. Bariatric surgery, colectomy and appendectomy have been other surgical procedures with some clinical experience in the use of the transvaginal approach. Analyzing the publications on transvaginal approach, we observed that the use of the vaginal route for non-gynecological abdominal surgery was not anecdotal, with accumulative experience of more than 3000 patients reported in published studies. The use of the vaginal route has shown its safety, obtaining some additional benefits such as the aesthetic and the faster functional recovery. Dyspareunia, one of the most feared, has not been reported in studies as a concern to consider.

关键词： Transvaginal Surgery Endoscopic Surgery Laparoscopy Flexible Endoscopy

欧盟联合研究中心参考文件玻璃制造业最佳适用技术参考文件工业排污指南

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欧盟联合研究中心参考文件玻璃制造业最佳适用技术参考文件工...

Rare germline copy number variants in colorectal cancer predisposition characterized by exome sequencing analysis

2014年全国玻璃窑炉技术研讨交流会

作者： SCALET Bianca Maria GARCIA munoz marcos SISSA Aivi Querol

5.5 BAT cpmc;isopms fpr dp,estoc g;ass,amifactiromg欧盟玻璃行业最佳适用技术的结论Unless otherwise stated,the BAT conclusions presented in this section can be applied to all domestic glass manufacturing installations.除非另有说明,本章中的结论适用于所有玻璃制造装置5.5.1 Dust emissions from melting furnaces熔窑的粉尘排放*** is to reduce dust emissions from the waste gases of the melting furnace by using one or a combination of the follwing techniques:采用下列一种或几种组合后的技术,能减少熔窑废气中的粉尘排放

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Journal of Genetics and Genomics 2018年第1期45卷 41-45页

作者： Sebastia Franch-Exposito Clara Esteban-Jurado Pilar Garre Isabel Quintanilla Saray Duran-Sanchon marcos Diaz-Gay Laia Bonjoch Miriam Cuatrecasas Esther Samper Jenifer munoz Teresa Ocana Sabela Carballal Maria Lopez-Ceron Antoni Castells Maria Vila-Casadesus Sophia Derdak Steven Laurie Sergi Beltran Jaime carvajal Luis Bujanda Clara Ruiz-Ponte Jordi Camps Meritxell Gironella Juan Jose Lozano Francesc Balaguer Joaquin Cubiella Trinidad Caldes Sergi Castellvi-Bel Gastroenterology Department Hospital Clinic de Barcelona August Pi i Sunyer Biomedical Research Institute CIBER of Hepatic and Digestive Diseases University of Barcelona Barcelona 08036 Spain Molecular Oncology Laboratory Hospital Clinico San Carlos Health Research Institute of the Hospital Clinico San Carlos Madrid 28040 Spain Department of Pathology Hospital Clinic de Barcelona Barcelona 08036 Spain EPICOLON consortium Bioinformatics Platform CIBER of Hepatic and Digestive Diseases Barcelona 08036 Spain National Center of Genomic Analysis Science Park of Barcelona Barcelona 08028 Spain Andalusian Developmental Biology Institute CSIC-Pablo de Olavide University-Andalusian Regional Government SeviUa 41013 Spain Gastroenterology Department Hospital Donostia-Biodonostia Institute CIBER of Hepatic and Digestive Diseases University of the Basque Country (UPV/EHU) San Sebastian 20080 Spain Galician Public Foundation of Genomic Medicine (FPGMX) CIBER of Rare Diseases Genomics Medicine Group Hospital Clinico Universitario University of Santiago de Compostela Santiago de Cornpostela 15706 Spain Castroenterology Department Complexo Hospitalario Universitario de Ourense Ourense Biomedical Research Institute Ourense 32005 Spain

Colorectal cancer （CRC） is one of the most common neoplasms and an important cause of mortality worldwide （http：//globocan. ***]）. Approximately 35% of the variation in CRC susceptibility is likely due to heritable factors （Lichtenstein et al., 2000}. Genetic variations in the human genome include single nucleotide variants （SNVs）, short insertions and deletions, and larger structural variants resulting in gain or loss of genomic DNA larger than 1 kb, such as copy number variants （CNVs）. Leaving aside the importance of CNVs in sporadic tumor development, these variants can also be present in the germline DNA of healthy individuals from the general population and be considered polymorphic.

关键词： WHOLE-EXOME GENE