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内脏脂肪组织通过产生骨桥蛋白调控成纤维细胞衰老促进心脏衰老

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中华高血压杂志 2018年第3期26卷 299-299页

作者： Sawaki D Czibik G Pini M Ternacle J Suffee N Mercedes R Marcelin G Surenaud M marcos E Gual P Clément K Hue S Adnot S Hatem SN Tsuchimochi I Yoshimitsu T Hénégar C Derumeaux G 刘青叶鹏

老化通过增加包括骨桥蛋白（osteopontin，OPN）在内的细胞外基质（extracellular matrix，ECM）蛋白的沉积引起心脏结构和功能改变进而导致进行性间质纤维化。虽然已知OPN参与各种病理状况，但其在心肌衰老中的作用仍不清楚。

关键词：骨桥蛋白成纤维细胞衰老内脏脂肪组织心脏衰老调控 matrix 细胞外基质间质纤维化

肺动脉高压中骨桥蛋白是衰老肺血管细胞表达的重要介质

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中华高血压杂志 2016年第9期24卷 862-862页

作者：刘莉叶鹏 Saker M Lipskaia L marcos E Abid S Parpaleix A Houssaini A Validire P Girard P Noureddine H Boyer L Vienney N Amsellem V Marguerit L Maitre B Derumeaux G Dubois-Rande JL Jourdan-Lesaux C Delcroix M Quarck R Adnot S

衰老的肺动脉平滑肌细胞（pulmonaryarterysmoothmusclecells，PA-SMC）可通过产生分泌因子促进肺高血压的发病。该研究的目的是探讨由衰老的PA-SMC释放的细胞外基质蛋白在肺高血压中的作用。方法：对正进行复制的衰老的人类PA-SMC进行... 详细信息

衰老的肺动脉平滑肌细胞（pulmonaryarterysmoothmusclecells，PA-SMC）可通过产生分泌因子促进肺高血压的发病。该研究的目的是探讨由衰老的PA-SMC释放的细胞外基质蛋白在肺高血压中的作用。方法：对正进行复制的衰老的人类PA-SMC进行聚合酶链反应阵列分析，发现骨桥蛋白上调，其介导了衰老PA-SMC介质和基质的刺激作用，以及对PA-SMC生长和迁移的作用。

关键词：骨桥蛋白肺血管肺动脉高压衰老细胞表达介质细胞外基质蛋白肺动脉平滑肌细胞

Role of Cognitive Behavioral Therapy in Fibromyalgia: A Systematic Review

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Open Journal of Rheumatology and Autoimmune Diseases 2021年第4期11卷 169-187页

作者： Heloisa Lima Heller Aline Rizzo Borges Luís Otávio Amarante Franco João Pedro De Oliveira Aucelio marcos Igor Albanaz Vargas Rebeca Naoum Lorga Mirella Bastos Sales Natália Vargas Do Nascimento Gabriela Furlan Ribeiro Barbosa Netto Beatriz Carneiro Passos Beatriz Pires Paes Beatriz Toledo Mendes Bruna De Paula Gonçalves Sousa Lyra Ciro Moisés Oliveira Vieira Dos Santos Gustavo Araújo Do Nascimento Santos Maria Luiza Pimentel De Oliveira Matheus Macêdo Da Silva Maurício Silva De Jesus Paulo Ricardo Guimaraes Rocha Storni Tamires Martinelli De Oliveira Ferraz Viviane Cristina Uliana Peterle Ana Paula Monteiro Gomides Reis Centro Universitário de Brasília Brasília Brazil Universidade Católica de Brasília Brasília Brazil Centro Universitário Euro Americano Brasília Brazil

A literature search of articles from 2002-2019 was performed using Medline, Embase, Cochrane, LILACS, IBECS, CRD, and Epistemonikos databases, to analyze the effects of Cognitive-Behavioral Therapy (CBT) in the treatment of fibromyalgia. Twenty-seven articles were selected in which CBT was performed exclusively by specialist physicians, associated or not with conventional pharmacological treatment and/or physical exercise. In most articles, CBT worked with self-knowledge and cognitive restructuring, attempting to reduce pain perception, and it showed a general improvement in daily activities by decreasing patient’s limitations, such as morning stiffness. The literature showed significant correlations of CBT in pain processing over time. When CBT was compared to conventional pharmacological therapy, a certain superiority of CBT could be observed concerning the quality of life, catastrophizing, and acceptance of pain. However, when they were simultaneously applied, this improvement in quality of life was not observed.

关键词： Cognitive Behavioral Therapy Fibromyalgia Pain

欧洲青少年心血管代谢风险与能量摄入误报的关系:欧洲青少年营养健康生活方式研究

维普期刊数据库评论

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中华高血压杂志 2021年第3期29卷 214-214页

作者：袁源(摘译) 练桂丽(审校) González-Gil EM Huybrechts I Aguilera CM Béghin L Breidenassel C Gesteiro E Gonzalez-Gross M de Henauw S Kersting M Donne CL Manios Y marcos A Meirhaeghe A De Miguel-Etayo P Molina-Hidalgo C Molnar D Papadaki A Widhalm K Moreno LA Bel-Serrat S 不详

膳食误报是膳食评估的主要局限性,且与青少年体质量指数(body mass index, BMI)相关。然而,之前没有研究评估青少年膳食误报与心血管代谢风险(cardiometabolic risk, CMR)的相关性。该研究旨在评估青少年膳食误报与CMR因素的相关性,并... 详细信息

膳食误报是膳食评估的主要局限性,且与青少年体质量指数(body mass index, BMI)相关。然而,之前没有研究评估青少年膳食误报与心血管代谢风险(cardiometabolic risk, CMR)的相关性。该研究旨在评估青少年膳食误报与CMR因素的相关性,并评估膳食误报所致能量摄入与CMR相关性的潜在偏倚。

关键词：青少年营养心血管代谢风险能量摄入体质量指数误报健康生活方式 CMR 膳食评估

2015年巴西寨卡病毒感染与小头畸形之间可能存在的关联

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上海预防医学 2017年第1期29卷 82-84页

作者： Lavinia Schuler-Faccini Erlane M.Ribeiro Ian M.L.Feitosa Dafne D.G.Horovitz Denise P.Cavalcanti AndréPessoa Maria Juliana R.Doriqui Joao Ivanildo Neri Joao Monteiro de Pina Neto Hector Y.C.Wanderley Mirlene Cernach Antonette S.El-Husny marcos V.S.Pone Cassio L.C.Serao Maria Teresa V.Sanseverino 朱秋丽(译) 陆仁敏(校) Universidade Federal do Rio Grande do Sul Brazil Hospital Infantil Albert Sabin FortalezaCEBrazil Universidade Federal de Pernambuco Brazil Fundaqao Oswaldo Cruz Rio de JaneiroBrazil University of Campinas Sao PauloBrazil Hospital Infantil Juvencio Mattos MaranhaoBrazil Universidade Potiguar Rio Grande do NorteBrazil University of Sao Paulo Ribeirao PretoBrazil Secretaria de Estado da Saude do Espirito Santo Brazil Universidade Federal de Sao Paulo Brazil Centro Universitario do Estado do Para Brazil Universidade do Estado do Rio de Janeiro Brazil Hospital de Clinicas de Porto Alegre Brazil Brazilian Medical Genetics Society-Zika Embryopathy Task Force 不详

2015年初,通过伊蚊传播的寨卡病毒在登革热病毒流行地区巴西的东北部暴发,该病毒属于黄病毒属。2015年9月,寨卡病毒流行地区开始出现关于小头畸形患儿的报道,且报道数量呈现增加的趋势。与此同时,有2名妇女产前超声检查发现有胎儿畸形,... 详细信息

2015年初,通过伊蚊传播的寨卡病毒在登革热病毒流行地区巴西的东北部暴发,该病毒属于黄病毒属。2015年9月,寨卡病毒流行地区开始出现关于小头畸形患儿的报道,且报道数量呈现增加的趋势。与此同时,有2名妇女产前超声检查发现有胎儿畸形,在她们的羊水中也检测出寨卡病毒RNA。

关键词：小头畸形病毒感染报道数量登革热病毒产前超声检查胎儿畸形西寨黄病毒属病毒流行先天性异常

Design of N-11-Azaartemisinins Potentially Active against Plasmodium falciparum by Combined Molecular Electrostatic Potential, Ligand-Receptor Interaction and Models Built with Supervised Machine Learning Methods

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Designing Artemisinins with Antimalarial Potential, Combining Molecular Electrostatic Potential, Ligand-Heme Interaction and Multivariate Models

Journal of Biophysical Chemistry（生物物理化学） 2023年第1期

作者： Jeferson Stiver Oliveira de Castro José Ciríaco Pinheiro Sílvia Simone dos Santos de Morais Heriberto Rodrigues Bitencourt Antonio Florêncio de Figueiredo marcos Antonio Barros dos Santos Fábio dos Santos Gil Ana Cecília Barbosa Pinheiro Instituto de Educação Ciência e Tecnologia do Pará Castanhal PA Brasil

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Sub-percent precision measurement of neutrino oscillation parameters with JUNO

Computational Chemistry（计算化学） 2023年第1期

作者： Josué de Jesus Oliveira Araújo Ricardo Morais de Miranda Jeferson Stiver Oliveira de Castro Antonio Florêncio de Figueiredo Ana Cecília Barbosa Pinheiro Sílvia Simone dos Santos Morais marcos Antonio Barros dos Santos Andréia de Lourdes Ribeiro Pinheiro Fábio dos Santos Gil Heriberto Rodrigues Bitencourt Gustavo Nery Ramos Alves José Ciríaco Pinheiro

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

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阿梅格尔巴克/哥本山

城市环境设计 2019年第2期 172-183页

作者： Nanna Gyldholm M?ller Alberto Cumerlato Aleksander Wadas Alexander Codda Alexander Ejsing Alexandra Gustafsson Alina Tamosiunaite Armor Gutierrez Anders Hjortn?s Andreas Klok Pedersen Annette Jensen Ariel Wallner Ask Andersen Balaj IIulian Blake Smith Borko Nikolic Brygida Zawadzka Buster Christensen Chris Falla Chris Zhongtian Yuan Daniel Selensky Dennis Rasmussen Espen Vik Finn N?rkj?r Franck Fdida Gonzalo Castro Gül Ertekin George Abraham Helen Chen Henrick Poulsen Henrik R?mer Kania Horia Spirescu Jakob Ohm Laursen Jelena Vucic Jeppe Ecklon Ji-young Yoon Jing Xu Joanna Jakubowska Johanna Nenander Kamilla Heskje Katarzyna Siedlecka Krzysztof Marciszewski Laura W?tte Liang Wang Lise Jessen Long Zuo Maciej Zawadzki Mads Enggaard Stidsen Marcelina Kolasinska marcos Bano Maren Allen Mathias Bank Matti N?rgaard Michael Andersen Narisara Ladawal Schr?der Niklas A. Rasch Nynne Madsen ?ssur Nols? Pero Vukovic Richard Howis Ryohei Koike Se Hyeon Kim Simon Masson Sunming Lee Toni Mateu Xing Xiong Zoltan David Kalaszi Rasmus Hjortshoj 陈子钰

垃圾焚烧发电厂阿梅格尔巴克/哥本山位于工业区,多年来,该工业区已成为冒险者们的极限运动目的地。原始的工业设施为各种极限运动活动提供了场所,如缆绳滑水、卡丁车和攀岩等。阿梅格尔巴克/哥本山是该地区最重要的地标,其建筑亟须更新... 详细信息

垃圾焚烧发电厂阿梅格尔巴克/哥本山位于工业区,多年来,该工业区已成为冒险者们的极限运动目的地。原始的工业设施为各种极限运动活动提供了场所,如缆绳滑水、卡丁车和攀岩等。阿梅格尔巴克/哥本山是该地区最重要的地标,其建筑亟须更新。我们提出了一种新型的垃圾焚烧发电厂,这种工厂能产生经济、环保和社会效益。我们不将阿梅格尔巴克/哥本山视为一个孤立的对象,而是调动起建筑的

关键词：巴克本山