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Relationship of Density of Specific Prostate Antigen (DPSA) with Prostate Histopathology: A Comparative Study of Patients Addressed in a School Hospital

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Journal of Biosciences and Medicines 2017年第3期5卷 105-111页

作者： marcos benedito figueiredo brandã o Maria Benedita figueiredo brandã o Elias Sobreira Sathler Richard Raphael Borges Tavares Vieira Carolina Cadinelli Vieira Pedro Kozlowsky de Alencar Marcus Vinicius de Mello Pinto Lamara Laguardia Valente Rocha Lina Claudia Pereira Lopes Daniel Almeida da Costa Carlos Henrique Diniz Branco Luiz Gioseffi Jannuzzi School Hospital of the Dom Andre Arcoverde Foundation Valen&ccedil a Brazil Universidade Está cio de Sá Rio de Janeiro Brazil The Medical School at the Center of Higher Education of Valenç a Valen&ccedil a Brazil The Cellurare Institute Center of Laser Treatment and Cell Therapy Petr&oacute polis Brazil The Medical School at the Health Sciences Institute of the University Center of Caratinga Caratinga Brazil

Background: The prostate is the site of problems that have great clinical relevance. Beside this, the alterations in their volume can be divided into benign or malignant pathologies, but of multifactorial cause and there is no examination that alone is reliable for the diagnosis. Despite the evolution of the various methods of diagnostic imaging in the evaluation of pelvic diseases, the diagnosis of prostate cancer still requires histological confirmation obtained by transrectal ultrasound guided biopsy, a procedure that is generally safe and well tolerated by the patients. The most common histological type found in prostate biopsies is adenocarcinoma. Methodology: The objective of this study was to study the values of density of the prostate-specific antigen (DPSA) compared to histopathological results of prostate biopsy, patients attended at the Urology Outpatient Clinic of the Luiz Gioseffi Jannuzzi School Hospital from 1999 to 2007, using Exploratory, retrospective and documentary descriptive study. The sample was divided into groups of patients with adenocarcinoma and patients without adenocarcinoma, who presented only benign prostatic hyperplasia. Results: Of the 251 patients undergoing prostate biopsy, 124 were diagnosed with adenocarcinoma and 127 without adenocarcinoma. It was observed in this study that the DPSA was higher in adenocarcinoma than in the cases of patients with prostatic hyperplasia alone, and could therefore be used as an auxiliary tool in both diagnosis and follow-up of patients with adenocarcinoma. Conclusion: In this study, it can be observed that DPSA was higher in patients presenting with adenocarcinoma than in patients presenting only Benign Prostatic Hyperplasia (BPH), reinforcing its promising role to assist in the diagnosis and follow-up of patients with adenocarcinoma.

关键词： Prostate Cancer Adenocarcinoma Benign Prostatic Hyperplasia Prostate Biopsy

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Cataracting-centrifuging transition investigation using nonspherical and spherical particles in a rotary drum through CFD simulations

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Particuology 2022年第1期20卷 48-60页

作者： Wanessa M.benedito Claudio R.Duarte marcos A.S.Barrozo Dyrney A.Santos Institute of Chemistry Federal University of Goias-UFGCampus SamambaiaGoianiaGO74690-900Brazil School of Chemical Engineering Federal University of Uberlandia-UFUCampus Santa MonicaUberlandiaMG38408-144Brazil

This paper aims to systematically investigate the cataracting-centrifuging transition in a rotary drum involving spherical and nonspherical particles by using the Multiphase Granular Eulerian Model(MGEM).The effects of drum length and particle shape on the cataracting-centrifuging transition behavior were *** results showed that drum length plays an important role in the cataracting-centrifuging transition,although most related works in the literature do not consider *** particle shape also significantly affects the cataracting-centrifuging transition *** particles required lower rotation speeds than spherical particles to reach the centrifuging *** particle shape was shown to be related to the critical solid fraction(asc)from Schaeffer’s model,although further investigations are required to completely correlate particle spherecity with critical solid volume fractions.

关键词： Frictional viscosity MGEM model Particle shape Drum length Drum flow regimes

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