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GIS tools for preliminary debris-flow assessment at regional scale

Journal of Mountain Science 2017年第12期14卷 2498-2510页

作者： cavalli marco crema stefano trevisani sebastiano marchi lorenzo consiglio nazionale delle ricerche istituto di ricerca per la protezione idrogeologicaCorso Stati Uniti 435127 PadovaItaly universitàdi padova dipartimento territorio e sistemi agro-forestaliVia dell’Universita 1635020 Legnaro(PD)Italy universitàiuav di venezia dipartimento di architettura costruzione conservazioneDorsoduro 220630123 VeneziaItaly

The assessment of the areas endangered by debris flows is a major issue in the context of mountain watershed management. Depending on the scale of analysis, different methods are required for the assessment of the areas exposed to debris *** 2-D numerical models are advised for detailed mapping of inundation areas on individual alluvial fans, preliminary recognition of hazard areas at the regional scale can be adequately performed by less data-demanding methods, which enable priority ranking of channels and alluvial fans at risk by debris flows. This contribution focuses on a simple and fast procedure that has been implemented for regionalscale identification of debris-flow prone channels and prioritization of the related alluvial fans. The methodology is based on the analysis of morphometric parameters derived from Digital Elevation Models(DEMs). Potential initiation sites of debris flows are identified as the DEM cells that exceed a threshold of slope-dependent contributing area. Channel reaches corresponding to debris flows propagation, deceleration and stopping conditions are derived from thresholds of local slope. An analysis of longitudinal profiles is used for the computation of the runout distance of debris flows. Information on erosion-resistant bedrock channels and sediment availability surveyed in the field are taken into account in the applications. A set of software tools was developed and made available(https://***/Hydrogeomorphology Tools) to facilitate the application of the procedure. This approach, which has been extensively validated by means of field checks, has been extensively applied in the eastern Italian Alps. This contribution discusses potential and limitations of the method in the frame of the management of small mountain watersheds.

关键词： Debris flow Geographic information system Digital elevation models Runout Alluvial fan Watershed management Geomorphometry

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Hemodynamic monitoring during liver transplantation:A state of the art review

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World Journal of Hepatology 2015年第10期7卷 1302-1311页

作者： Mona Rezai Rudnick lorenzo De marchi Jeffrey S Plotkin Department of Anesthesiology Georgetown University Hospital

Orthotopic liver transplantation can be marked by significant hemodynamic instability requiring the use of a variety of hemodynamic monitors to aide in intraoperative management. Invasive blood pressure monitoring is essential,but the accuracy of peripheral readings in comparison to central measurements has been questioned. When discrepancies exist,central mean arterial pressure,usually measured at the femoral artery,is considered more indicative of adequateperfusion than those measured peripherally. The traditional pulmonary artery catheter is less frequently used due to its invasive nature and known limitations in measuring preload but still plays an important role in measuring cardiac output(CO) when required and in the management of portopulmonary hypertension. Pulse wave analysis is a newer technology that uses computer algorithms to calculate CO,stroke volume variation(SVV) and pulse pressure variation(PPV). Although SVV and PPV have been found to be accurate predicators of fluid responsiveness,CO measurements are not reliable during liver transplantation. Transesophageal echocardiography is finding an increasing role in the realtime monitoring of preload status,cardiac contractility and the diagnosis of a variety of pathologies. It is limited by the expertise required,limited transgastric views during key portions of the operation,the potential for esophageal varix rupture and difficulty in obtaining quantitative measures of CO in the absence of tricuspid regurgitation.

关键词： Intraoperative monitoring Physiologicmonitoring Liver transplantation

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Irritable bowel syndrome and chronic constipation: Fact and fiction

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World Journal of Gastroenterology 2015年第40期21卷 11362-11370页

作者： Massimo Bellini Dario Gambaccini Paolo Usai-Satta Nicola De Bortoli lorenzo Bertani Santino marchi Cristina Stasi Gastrointestinal Unit Department of GastroenterologyUniversity of Pisa Gastrointestinal Unit P. Brotzu Hospital Department of Experimental and Clinical Medicine University of Florence Epidemiological Observatory Regional Health Agency of Tuscany

Irritable bowel syndrome(IBS) and functional constipation(FC) are the most common functional gastrointestinal disorders. According to the Rome ⅢCriteria these two disorders should be theoretically separated mainly by the presence of abdominal pain or discomfort relieved by defecation(typical of IBS) and they should be mutually exclusive. However,many gastroenterologists have serious doubts as regards a clear separation. Both IBS-C and FC,often associated with many other functional digestive and non digestive disorders,are responsible for a low quality of life. The impact of the media on patients' perception of these topics is sometimes disruptive,often suggesting a distorted view of pathophysiology,diagnosis and therapy. These messages frequently overlap with previous subjective opinions and are further processed on the basis of the different culture and the previous experience of the constipated patients,often producing odd,useless or even dangerous behaviors. The aim of this review was to analyze the most common patients' beliefs about IBS-C and CC,helping physicians to understand where they should focus their attention when communicating with patients,detecting false opinions and misconceptions and correcting them on the basis of scientific evidence.

关键词： Irritable bowel syndrome Chronic constipation Func

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Barrett's esophagus in 2016: From pathophysiology to treatment

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2016年第2期7卷 190-206页

作者： Irene Martinucci Nicola de Bortoli Salvatore Russo lorenzo Bertani Manuele Furnari Anna Mokrowiecka Ewa Malecka-Panas Vincenzo Savarino Edoardo Savarino Santino marchi Division of Gastroenterology University of Pisa Division of Gastroen terology University of Genoa Department of Digestive Tract Diseases Medical University of Lodz Division of Gastroenterology University of Padua

Esophageal complications caused by gastroesophageal reflux disease(GERD)include reflux esophagitis and Barrett’s esophagus(BE).BE is a premalignant condition with an increased risk of developing esophageal adeno-carcinoma(EAC).The carcinogenic sequence may progress through several steps,from normal esophageal mucosa through BE to EAC.A recent advent of functional esophageal testing(particularly multichannel intraluminal impedance and pH monitoring)has helped to improve our knowledge about GERD pathophysiology,including its *** findings(when properly confirmed)might help to predict BE neoplastic *** the last few decades,the incidence of EAC has continued to rise in Western ***,only a minority of BE patients develop EAC,opening the debate regarding the cost-effectiveness of current screening/surveillance ***,major efforts in clinical and research practice are focused on new methods for optimal risk assessment that can stratify BE patients at low or high risk of developing EAC,which should improve the cost effectiveness of screening/surveillance programs and consequently significantly affect health-care ***,the area of BE therapeutic management is rapidly *** eradication therapies have been shown to be effective,and new therapeutic options for BE and EAC have *** aim of the present review article is to highlight the status of screening/surveillance programs and the current progress of BE ***,we discuss the recent introduction of novel esophageal pathophysiological exams that have improved the knowledge of the mechanisms linking GERD to BE.

关键词： Gastroesophageal reflux disease Barrett’s esophagus Esophageal adenocarcinoma Impedance and pH monitoring Endoscopy

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Esophageal testing: What we have so far

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World Journal of Gastrointestinal Pathophysiology 2016年第1期7卷 72-85页

作者： Nicola de Bortoli Irene Martinucci lorenzo Bertani Salvatore Russo Riccardo Franchi Manuele Furnari Salvatore Tolone Giorgia Bodini Valeria Bolognesi Massimo Bellini Vincenzo Savarino Santino marchi Edoardo Vincenzo Savarino Gastroenterology Unit Department of Translational Research and New Technologies in Medicine and SurgeryUniversity of Pisa Gastroenterology Unit Department of Internal MedicineUniversity of Genoa Surgery Unit Department of SurgerySecond University of Naples Gastroenterology Unit Department SurgeryOncology and GastroenterologyUniversity of Padua

Gastroesophageal reflux disease(GERD) is a common disorder of the gastrointestinal tract. In the last few decades, new technologies have evolved and have been applied to the functional study of the esophagus, allowing for the improvement of our knowledge of the pathophysiology of GERD. High-resolution manometry(HRM) permits greater understanding of the function of the esophagogastric junction and the risks associated with hiatal hernia. Moreover, HRM has been found to be more reproducible and sensitive than conventional water-perfused manometry to detect the presence of transient lower esophageal sphincter relaxation. Esophageal 24-h p H-metry with or without combined impedance is usually performed in patients with negative endoscopy and reflux symptoms who have a poor response to anti-reflux medical therapy to assess esophageal acid exposure and symptom-reflux correlations. In particular, esophageal 24-h impedance and p H monitoring can detect acid and non-acid reflux events. Endo FLIP is a recent technique poorly applied in clinical practice, although it provides a large amount of information about the esophagogastric junction. In the coming years, laryngopharyngeal symptoms could be evaluated with up and coming non-invasive or minimally invasive techniques, such as pepsin detection in saliva or pharyngeal p H-metry. Future studies are required of these techniques to evaluate their diagnostic accuracy and usefulness, although the available data are promising.

关键词： Gastroesophageal reflux disease Highresolution manometry Multichannel impedance and pH BRAVO EndoFLIP PEP-test Restech

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