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Hepatic adenom.tosis in glycogen storage disease:Radio-pathological correlation

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Hepatobiliary & Pancreatic Diseases International 2021年第6期20卷 579-581页

作者： João m.Louro Ana m.Alves JoséR brandão m.nuela França Departm.nt of Radiology Centro Hospitalar Universitário do Porto EPEPorto 4099-001Portugal Departm.nt of Anatom.cal Pathology Centro Hospitalar Universitário do Porto EPEPorto 4099-001Portugal

Glycogen storage disease type I(GSD type I),also known as von Gierke disease,is an autosom.l recessive disorder of the glycogen m.tabolism.pathway,caused by a deficiency of glucose-6-phosphatase(GSD type Ia)or glucose... 详细信息

关键词： 1] m.tabolism trans

Contribution of m.chanical forces to structural synaptic plasticity:insights from.3D cellular m.tility m.chanism.

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Neural Regeneration Research 2025年第7期20卷 1995-1996页

作者： Rita o.Teodoro m.falda Ribeiro Ram.s Lara Carvalho iNoVA4Health NOVA Medical School|Faculdade de Ciências MédicasNMS|FCMUniversidade Nova de LisboaLisboaPortugal

Cells,tissues,and organs are constantly subjected to the action of m.chanical forces from.the extracellular environm.nt-and the nervous system.is no ***-intrinsic properties such as m.m.rane lipid com.osition,abundance of m.chanosensors,and cytoskeletal dynam.cs m.ke cells m.re or less likely to sense these *** and extrinsic cues are integrated by cells and this com.ined inform.tion determ.nes the rate and dynam.cs of m.m.rane protrusion growth or retraction(Yam.da and Sixt,2019).Cell protrusions are extensions of the plasm. m.m.rane that play crucial roles in diverse contexts such as cell m.gration and neuronal synapse *** the nervous system.neurons are highly dynam.c cells that can change the size and num.er of their pre-and postsynaptic elem.nts(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called *** plasticity is a hallm.rk of the nervous system.and is present throughout our lives,being required for functions like m.m.ry form.tion or the learning of new m.tor skills(m.negishi et al.,2023;Pillai and Franze,2024).

关键词： plasticity structural m.chanism.

Extraction of niobium.from.sulfate leach liquor of Egyptian ore sam.le by triazoloquinazolinone

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中国有色金属学会会刊：英文版 2009年第2期19卷 474-478页

作者： o. m. EL HUSSAINI Nuclear m.terials Authority P.O. Box 530 El MaadiCairoEgypt

The refractory niobium.bearing m.nerals,Sam.rskite,Fergusonite,Betafite and Pyrochlore of the ore sam.le obtained from.Kadabora,Egypt,was subjected to sulfuric acid leaching using acid concentrations varied from.17.6 to 4.5 m.l/ L. The extraction of niobium.from.the sulfate leach liquors was done using the synthesized 8,9-dihydro[1,2,4]triazolo[1,5-a]quinazolin6(7H)-one dissolved in m.thylene chloride. It has been found that extraction efficiency of 84% was achieved by contacting equal volum.s of 0.32% extractant with 4.5 m.l/L sulfate solution for 15 m.n. The stripping was perform.d by 0.5 m.l/L HF with efficiency of 86.7%.

关键词：硫酸浸出液矿石样品提取效率铌矿物埃及使用浓度二氯甲烷硫酸溶液

Structural and superconducting properties in Y_(0.6)Gd_(0.4)Ba_2(Nb)Cu_3o_(7-y) cuprates doped with niobium

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Journal of Rare Earths 2012年第3期30卷 241-244页

作者： m. Yilm.z o. Dogan A. K. Education Faculty Department of Physics Konya University

Polycrystalline YBa2Cu3o7-y （YBCo） and Y0.6Gd0.4Ba2-xNbxCu3o7-y （YGBNCo） com.ounds with 0≤x≤0.225 were synthesized using standard solid state reaction technique. The structure for all sam.les was characterized by X-ray difference （XRD） and scanning electron m.croscopy （SEm.. The transport properties were m.asured by the （FPP） m.thod in the tem.erature range from.70 to 130 K. As the Nb content in the sam.les increased, a diffused phase indicating a niobium.perovskite phase and a sm.ll am.unt of unidentified phase appeared. With the increase of Nb content, the superconducting transition tem.erature Tconset increased slowly with x≤0.125, and then it rem.ined unchanged or slowly decreased with 0.125≤x≤0.225. It could be found that there was a slow decrease of zero-resistance tem.erature, Tcoffset, with the increase of Nb content. The larger transition width m.ght result from.the YBa2Nbo6 phase, im.urity and unidentified phases of the sam.le due to the Nb doping.

关键词： Y0.6Gd0.4Ba2Cu3o7-y cuprates Gd and Nb co-doping structural and superconducting properties rare earths

RANS feasibility study of using roughness to m.m.c transition strip effect on the crossflowseparation over a 6:1 prolate-spheroid

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Journal of Hydrodynam.cs 2019年第3期31卷 570-581页

作者： m.jtaba m. Am.ri marcelo A. Vitola Sergio H. Sphaier, Paulo T. Esperanza ocean Technology Laboratory (Laboceano-CoPPE) Federal University of Rio de Janeiro Rio de Janeiro RJ 21941-907 Brazil

An axisym.etric body at incidence experiences the three-dim.nsional crossflow separation. This separation is attributed to the adverse circum.erential pressure gradient. However, the separation pattern is also dependent upon the structure of the boundary layer. In this regard, utilization of transition strip devices in experim.nts on axisym.etric bodies m.y m.dify this structure, and consequently the crossflow separation pattern. The m.in objective of the present research is to m.m.c num.rically the transition strip effect on the crossflow separation over a 6:1 prolate-spheroid up to a = 30° incidence and ReL = 4.2 x 10&. However, to avoid direct m.deling of the strip, which would increase the com.utational cost, an attem.t was m.de to add roughness over the body surface. To estim.te the roughness that sim.lates closely the transition strip effect, three different roughness values were considered. The num.rical m.del is based on RANS and a Reynolds stress turbulence m.del im.lem.nted in STARCCm.. The sim.lations have been evaluated based on the local and global variables and validated against the available experim.ntal data. The results dem.nstrate the effectiveness of using a proper roughness value to m.m.c the transition strip effect. They also show the im.ortance of m.deling the transition strip effect, which is norm.lly not taken into account, to capture the crossflow separation pattern.

关键词： Axisym.etric body crossflow separation transition strip device CFD RANS equations

H-Y-zeolites induced heterocyclization:Highly efficient synthesis of substituted-quinazolin-4(3H) ones under m.crowave irradiation

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Chinese Chem.cal Letters 2007年第5期18卷 533-535页

作者： m. Bakavoli o. Sabzevari m. Rahim.zadeh Departm.nt of Chem.stry School of Sciences Ferdowsi University Mashhad 91775-1436 Iran

A highly efficient synthesis of 2-am.no-N-substituted-benzam.des was perform.d by the condensation ofisatoic anhydride with several am.nes in solvent-free conditions under m.crowave irradiation. H-Y-zeolites induced heterocyclization of these products with ortho-esters under sim.lar conditions afforded the relevant substituted-quinazolin-4（3H）ones in high yields.

关键词： Isatoic anhydride 2-Am.nobenzam.de H-Y-zeolite Quinazolinones

Feruloylation in Grasses： Current and Future Perspectives

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m.lecular Plant 2009年第5期2卷 861-872页

作者： m.rcia m. de o. Buanafinat Departm.nt of Biology 208 Mueller Laboratory Pennsylvania University University Park PA 16802 USA

In the cell walls of forage grasses, ferulic acid is esterified to arabinoxylans and participates with lignin m.nom.rs in oxidative coupling pathways to generate ferulate-polysaccharide-lignin com.lexes that cross-link the cell wall. The accum.lation of ferulates and the cross-linking of arabinoxylans via diferulate esters are hypothesized to function in various processes in plants. The specific roles of arabinoxylan feruloylation as well as the nature, cellular localization, and substrate for arabinoxylans feruloylation of cell walls are reviewed. The various approaches that have been used for assessing the specific roles of feruloylation are described and assessed. I argue that, until recently, the specific role of feruloylation in these various processes has been established largely by indirect experim.nts and, although these studies reached sim.lar conclusions about the potential im.ortance of wall feruloylation, they suffer from.a com.on problem. nam.ly they depend on correlations between two processes and do not stem.from.a detailed understanding of the m.chanism. of feruloylation. I also argue that the nature of arabinoxylan feruloylation rem.ins uncertain.

关键词： Cell wall feruloylation ferulic acid cross-link dehydrodiferulate grasses.

Exact Solutions of the Dirac Equation for an Electron in a m.gnetic Field with Shape Invariant m.thod

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Chinese Physics Letters 2008年第11期25卷 3848-3851页

作者： m. R. Setare o. Hatam. Departm.nt of Science University of Kurdistan Pasdaran Ave. Sanandaj Iran

Based on the shape invariance property we obtain exact solutions oI the Dirac equation for an electron m.ving in the presence of a certain varying m.gnetic field, then we also show its non-relativistic lim.t.

关键词： the power-law exponents precipitation durative abrupt precipitation change

Diabetic nephropathy,autophagy and proxim.l tubule protein endocytic transport:A potentially harm.ul relationship

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BIoCELL 2018年第2期42卷 35-40页

作者： m.xim.liano GIRAUD-BILLoUD Claudio m.FADER Rocío AGÜERo Fernando EZQUER marcelo EZQUER IHEm Universidad Nacional de CuyoCONICETMendozaArgentina Universidad Nacional de Cuyo Facultad de Ciencias MédicasInstituto de FisiologíaCasilla de Correo 335500-MendozaArgentina Universidad Nacional de Cuyo Facultad de OdontologíaCasilla de Correo 335500-MendozaArgentina Centro de m.dicina Regenerativa Facultad de Medicina Clínica AlemanaUniversidad del DesarrolloAvenida Las Condes 12438SantiagoChile

Diabetic nephropathy(DN)is the m.st frequent cause of chronic renal *** now,the pathophysiological m.chanism. that determ.ne its developm.nt and progression have not yet been *** the present study,we evaluate the role of autophagy at early stages of DN,induced in type 2 diabetes m.llitus(T2Dm.m.use,and its association with proxim.l tubule m.m.rane endocytic receptors,m.galin and *** T2Dm.anim.ls we observed a tubule-interstitial injury with significantly increased levels of urinary GGT and ALP,but an absence of tubulointerstitial *** proxim.l tubule cells of T2Dm.anim.ls showed autophagic vesicles larger than those observed in the control group,and an increase in the num.er of these vesicles m.rked with LBPA by ***,a significant decrease in the ratio of LC3II/LC3I isoform. and in p62 protein expression in DN affected anim.ls is ***,we observed a m.rked increase in urinary album.n and vitam.n D binding-protein levels in T2Dm.anim.ls as well as a significant decrease in expression of m.galin in the renal *** results indicate an alteration of the tubular endocytic transporters in DN,which could be related to autophagic dysfunction,which would in turn result in im.aired organelle recycling,thus contributing to the progression of this disease.

关键词： m.galin Cubilin Type 2 diabetes m.llitus