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Exploring overweight and obesity beyond body mass index:A body composition analysis in people with and without patellofemoral pain

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Journal of Sport and Health Science 2023年第5期12卷 630-638,F0003页

作者： Amanda Schenatto Ferreira Benjamin F Mentiplay Bianca Taborda marcella ferraz pazzinatto Fabio Mıcolis de Azevedo Danilo De Oliveira Silva Department of Physiotherapy School of Science and TechnologySao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil La Trobe Sport and Exercise Medicine Research Centre School of Allied HealthHuman Services and SportLa Trobe UniversityMelbourneVIC 3086Australia

Background:We compared body mass index(BMI),body fat,and skeletal muscle mass between(1) a mixed-sex nonathletic cohort of people with patellofemoral pain(PFP) and pain-free people,and(2) a nonathletic cohort of people with PFP and pain-free people subgrouped by sex(i.e.,men and women with PFP ***-free men and women).Methods:This cross-sectional study included 114 people with PFP(71 women,43 men) and 54 pain-free controls(32 women,22 men).All participants attended a single testing session to assess body composition measures,which included BMI,percentage of body fat(%BFBioimpedance),and skeletal muscle mass(both assessed by bioelectrical impedance analysis),and percentage of body fat(%BFskinfoid)(assessed by skinfold caliper analysis).A one-way univariate analysis of covariance(age and physical activity levels as covariates) was used to compare body composition measures between groups(i.e.,PFP ***-free group;women with PFP ***-free women;men with PFP ***-free men).Results:Women with PFP presented significantly higher BMI,%BFBiompedance,and %BFSkinfold,and lower skeletal muscle mass compared to pain-free women(p≤0.04;effect size:-0.47 to 0.85).Men with PFP and men and women combined had no differences in BMI,%BFBioimpedance,%BFSkinfold,and skeletal muscle mass compared to their respective pain-free groups(p> 0.05).Conclusion:Our findings indicate that BMI and body composition measures should be considered as part of the evaluation and management of people with PFP,especially in women,who have demonstrated higher BMI and body fat and lower skeletal muscle mass compared to pain-free *** studies should not assess body composition measures in a mixed-sex population without distinguishing men participants from women participants.

关键词： Body composition Body mass index Patellofemoral pain syndrome Skinfold thicknessTagedEnd

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Overweight and obesity in young adults with patellofemoral pain:Impact on functional capacity and strength

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Journal of Sport and Health Science 2023年第2期12卷 202-211页

作者： Amanda Schenatto Ferreira Benjamin FMentiplay Bianca Taborda marcella ferraz pazzinatto Fábio Mícolis de Azevedo Danilo de Oliveira Silva Department of Physiotherapy School of Science and TechnologySao Paulo State University(UNESP)Presidente Prudente19060-900Brazil La Trobe Sport and Exercise Medicine Research Centre School of Allied HealthHuman Services and SportLa Trobe UniversityMelbourneVIC 3086Australia

Purpose:This study aimed to(a)investigate the proportion of overweight/obesity in a cohort of young adults with patellofemoral pain(PFP)and(b)explore the association of body mass index(BMI),body fat,and lean mass with functional capacity and hip and knee strength in people with ***:We included a mixed-sex sample of young adults(18-35 years old)with PFP(n=100).Measurements for BMI,percentage of body fat,and lean mass(assessed by bioelectrical impedance)were *** capacity was assessed by the Anterior Knee Pain Scale,plank test,and single-leg hop *** of the knee extensors,knee flexors,and hip abductors was evaluated isometrically using an isokinetic *** proportion of overweight/obesity was calculated based on *** association between BMI,body fat,and lean mass and functional capacity and strength was investigated using partial correlations,followed by hierarchical regression analysis,adjusted for covariates(sex,bilateral pain,and current pain level).Results:A total of 38%of our cohort had their BMI categorized as overweight/*** BMI was associated with poor functional capacity(ΔR^(2)=0.06-0.12,p<0.001)and with knee flexion strength only(ΔR^(2)=0.04,p=0.030).Higher body fat was associated with poor functional capacity(ΔR^(2)=0.05-0.15,p≤0.015)and reduced strength(ΔR^(2)=0.15-0.23,p<0.001).Lower lean mass was associated with poor functional capacity(ΔR^(2)=0.04-0.13,p≤0.032)and reduced strength(ΔR^(2)=0.29-0.31,p<0.001).Conclusion:BMI,body fat,and lean mass should be considered in the assessment and management of young people with PFP because it may be detrimental to function and strength.

关键词： Body fat distribution Body mass index Patellofemoral pain syndrome Torque

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Clinical/Behavioral Monitoring of Rodents and Rabbits Undergoing Scientific Experiments

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Open Journal of Veterinary Medicine 2024年第5期14卷 91-109页

作者： Luiz Cesar Cavalcanti Pereira Jhônata Willy Rocha Coelho Hyago da Silva Medeiros Elidio Rita de Cássia dos Passos ferraz Da Silva João Gabriel Regis Sobral Bárbara Alves de Brito Soledade Leandro Thomaz Vilela Isabele Barbieri Dos Santos Institute of Science and Technology in Biomodels (ICTB) Oswaldo Cruz Foundation (FIOCRUZ) Rio de Janeiro Brazil Laboratory Animal Facility of the Carlos Chagas Pavilion of the Animal Experimentation Center (CEA) Oswaldo Cruz Institute (IOC) Oswaldo Cruz Foundation (FIOCRUZ) Rio de Janeiro Brazil

Background: We currently have international and national guidelines regarding the assessment and monitoring of clinical signs and humane endpoints in animals used in teaching and research, which make the performance of these activities mandatory for any experiment and professional working in this area. Assigning the severity of a research experiment is the result of an analysis of records of observations of the animal’s behavior, and clinical signs. The aim of this study was to describe the importance of carrying out a severity assessment associated with clinical and behavioral monitoring of rodents and rabbits during experimentation to maintain the welfare of these animals undergoing scientific research. Methods: The literature search was carried out using the following terms: “Monitoring”;“Humane endpoints”;“Animal welfare”, “Rodents”;“Rabbits”, and as connectors “and”;“or”, in the following databases: PubMed;LILACS/BIREME and SciELO. Results: A total of 987 articles were identified in the databases, and 20 of these studies were included in this review. Conclusions: Humane endpoint protocols and procedure severity tables are of the utmost importance, both from an ethical point and to refine the results of research conducted on laboratory animals. They should be drawn up jointly by the teams responsible for the project and the maintenance of the animals during the research period, and the data obtained should be published so that the scientific community can have access to it, helping to disseminate these practices, as well as helping to draw up new procedures. Monitoring and evaluating the welfare and clinical condition of animals undergoing scientific research procedures is the responsibility of the professors, researchers, veterinarians, and animal facility coordinators. The Ethics Committee on the Use of Animals must monitor all the activities conducted with the animals, by inspecting the experimental procedures and the physical environment of the laboratory an

关键词： Monitoring Humane Endpoints Animal Welfare Experimental Design Laboratory Animals’ Investigations

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Multi-planet extrasolar systems-detection and dynamics

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Research in Astronomy and Astrophysics 2012年第8期12卷 1044-1080页

作者： Cristian Beaug Sylvio ferraz-Mello Tatiana A.Michtchenko Instituto de Astronomía Teóricay Experimental Observatório Astronómico de CórdobaUniversidad de CórdobaArgentina Instituto de Astronomia Geofísica e Cie ncias AtmosfricasUniversidade de So PauloBrasil

20 years after the discovery of the first planets outside our solar system, the current exoplanetary population includes more than 700 confirmed planets around main sequence stars. Approximately 50% belong to multiple-planet systems in very diverse dynamical configurations, from two-planet hierarchical systems to multiple resonances that could only have been attained as the consequence of a smooth large- scale orbital migration. The first part of this paper reviews the main detection tech- niques employed for the detection and orbital characterization of multiple-planet sys- tems, from the （now） classical radial velocity （RV） method to the use of transit time variations （TTV） for the identification of additional planetary bodies orbiting the same star. In the second part we discuss the dynamical evolution of multi-planet systems due to their mutual gravitational interactions. We analyze possible modes of motion for hi- erarchical, secular or resonant configurations, and what stability criteria can be defined in each case. In some cases, the dynamics can be well approximated by simple ana- lytical expressions for the Hamiltonian function, while other configurations can only be studied with semi-analytical or numerical tools. In particular, we show how mean- motion resonances can generate complex structures in the phase space where different libration islands and circulation domains are separated by chaotic layers. In all cases we use real exoplanetary systems as working examples.

关键词： planetary systems -- planetary systems: formation

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Multidrug-resistant bacterial infections after liver transplantation: An ever-growing challenge

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World Journal of Gastroenterology 2014年第20期20卷 6201-6210页

作者： Guilherme Santoro-Lopes Erika ferraz de Gouvêa Infectious Diseases Clinic Hospital Universitário Clementino Fraga Filho Universidade Federal do Rio de Janeiro Rio de Janeiro RJ-CEP 21941-913 Brazil Department of Preventive Medicine School of Medicine Universidade Federal do Rio de Janeiro Rio de Janeiro RJ-CEP 21941-590 Brazil

Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant *** the last two decades,various multidrug-resistant(MDR)pathogens have emerged as relevant causes of infection in this *** this fact reflects the spread of MDR pathogens in health care facilities worldwide,several factors relating to the care of transplant donor candidates and recipients render these patients particularly prone to the acquisition of MDR bacteria and increase the likelihood of MDR infectious outbreaks in transplant *** awareness of this high vulnerability of transplant recipients to infection leads to the more frequent use of broad-spectrum empiric antibiotic therapy,which further contributes to the selection of drug *** vicious cycle is difficult to avoid and leads to a scenario of increased complexity and narrowed therapeutic *** by MDR pathogens is more frequently associated with a failure to start appropriate empiric antimicrobial *** lack of appropriate treatment may contribute to the high mortality occurring in transplant recipients with MDR ***,high therapeutic failure rates have been observed in patients infected with extensively-resistant pathogens,such as carbapenemresistant Enterobacteriaceae,for which optimal treatment remains *** such a context,the careful implementation of preventive strategies is of utmost importance to minimize the negative impact that MDR infections may have on the outcome of liver transplant *** article reviews the current literature regarding the incidence and outcome of MDR infections in liver transplant recipients,and summarizes current preventive and therapeutic recommendations.

关键词： Multidrug resistance Bacterial infections Organ transplantation Methicillin-resistant Staphylococcus aureus Liver transplantation

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The coppice-with-standards silvicultural system as applied to Eucalyptus plantations-a review

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Journal of Forestry Research 2014年第2期25卷 237-248页

作者： Antonio Carlos ferraz FILHO José Roberto Soares SCOLFORO Blas MOLA-YUDEGO Departamento de Ciências Florestais Universidade Federal de Lavras (UFLA) School of Forest Sciences University of Eastern Finland (UEF)

We review the management of Eucalyptus species under a coppice-with-standards （CWS） silvicultural system. CWS management results in product diversification, permitting production of small and large scale timber from the same stand. Eucalyptus species are suitable candidates for CWS management because： there are large worldwide plantation areas, sprouting capacity is high, and eucalypts are multipur- pose species. We discuss （1） short rotation Eucalyptus coppice manage- ment for energy and pulping and （2） Eucalyptus seedling management for solid wood products. We review the literature and discuss experi- ences with Eucalyptus managed under the CWS system. We also assess projects dealing with Eucalyptus coppice management, stand density regulation, pruning, and stand and wood quality. The growth environ- ment of the standard trees （heavy competition up to the first harvest, free growth afterwards） coupled with long rotations （〉20 years） results in high quality logs for solid wood products. Early pruning should be ap- plied to enhance wood quality. We propose a system for the silvicultural management of Eucalyptus under the CWS system, elaborating on the consequences of initial planting density, site productivity, and standard tree densities as well as timing of basic silvicultural applications.

关键词： stand density regulation coppice management pruning silvicultural system stand production diversification CWS

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The influence of different exercise intensities on kicking accuracy and velocity in soccer players

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Journal of Sport and Health Science 2017年第4期6卷 462-467页

作者： Ricardo ferraz Roland van den Tillar Mario C. Marques Department of Sports Sciences University of Beira Interior Convento de St Antonio Covilha 6200-001 Portugal Research Center in Sport Sciences Health Sciences and Human Development CIDESD Vila Real 5000-801 Portugal Department of Teacher Education Nord Trondelag University College Levanger 7600 Norway

Purpose: The aim of this study was to investigate the influence of different exercise intensities induced by a soccer specific protocol on kicking performance in soccer ***: Twelve semi-professional male soccer players participated in this study and performed maximal instep kicks before and after the implementation of an exercise protocol to determine the influence of different intensities upon kicking ball velocity and the target-hitting ***: Analysis of variance designs with repeated measures showed that maximal ball velocity was affected only after the most intense circuit(F(6, 66) = 2.3; p = 0.041; η2= 0.18), while accuracy was not affected in the protocol(F(6, 66) = 0.19; p = 0.98; η2= 0.02). Low and moderate intensities did not affect accuracy or kicking ball ***: These findings suggest that kicking ball velocity is influenced by high-exercise intensities. Low and moderate exercise intensities do not affect the performance of the kick, and intensity does not influence accuracy. Otherwise, it is possible that other mechanisms(not only physiological) may influence players during the exercise.

关键词： Exercise intensity Fatigue Kicking soccer Pacing

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Main visual symptoms associated with refractive errors and spectacle need in a Brazilian population

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International Journal of Ophthalmology(English edition) 2016年第11期9卷 1657-1662页

作者： Silvana Schellini Fabio ferraz Paula Opromolla Laryssa Oliveira Carlos Padovani Botucatu Medical School University of State of Sao Paulo

AIM： To determine the main visual symptoms in a Brazilian population sample, associated to refractive errors（REs） and spectacle need to suggest priorities in preventive ***： A cross-sectional study was conducted in nine counties of the southeast region of Brazil, using a systematic sampling of households, between March 2004 and July 2005. The population was defined as individuals aged between 1 and 96 y, inhabitants of 3600 residences to be evaluated and 3012 households were included,corresponding to 8010 subjects considered for participation in the survey, of whom 7654 underwent ophthalmic examinations. The individuals were evaluated according their demographic data, eye complaints and eye examination including the RE and the need to prescribe spectacles according to age. Statistical analysis was performed using SPSS software package and descriptive analysis using 95% confidence intervals（P〈0.05）. RESULTS： The main symptom detected was asthenopia, most frequent in the 2ndand 3rddecades of life, with a significant decline after the *** was the RE most associated with asthenopia. Reduced near vision sight was more frequent in those ≥40y with a progressive decline *** were most frequently required in subjects of≥40 years of ***： The main symptom related to the vision was asthenopia and was associated to astigmatism. The greatest need for spectacles prescription occurred after40＇s, mainly to correct near vision. Subjects of ≥40years old were determined to be at high risk of uncorrected REs. These observations can guide intervention programs for the Brazilian population.

关键词： population study visual symptoms refractive error spectacle need

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The neuroprotective effect of traditional Chinese medicinal plants--A critical review

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Acta Pharmaceutica Sinica B 2023年第8期13卷 3208-3237页

作者： Joao Moreira Mariana Machado Monica Dias-Teixeira Ricardo ferraz Cristina Delerue-Matos Clara Grosso REQUIMTE/LAQV Instituto Superior de Engenharia do PortoInstituto Politecnico do PortoPorto 4249-015Portugal Ciencias Químicas e das Biomoleculas/CISA Escola Superior de SaudedInstituto Politecnico do PortoPorto 4200-072Portugal NICiTeS-Nucleo de Investigacao em Ciencias e Tecnologias da Saude Escola Superior de Saude Ribeiro SanchesLisboa 1950-396Portugal REQUIMTE/LAQV Departamento de Química e Bioquímica Faculdade de CienciasUniversidade do PortoPorto 4169-007Portugal

Neurodegenerative and neuropsychiatric diseases are increasingly affecting individuals’quality of life,thus increasing their cost to social and health *** diseases have overlapping mechanisms,such as oxidative stress,protein aggregation,neuroinflammation,neurotransmission impairment,mitochondrial dysfunction,and ***,there is no cure for neurodegenerative diseases,and the available therapies have adverse effects and low *** neuropsychiatric disorders,such as depression,the current therapies are not adequate to one-third of the patients,the so-called treatmentresistant ***,searching for new treatments is *** plants appear as a strong alternative and complement towards new treatment protocols,as they have been used for health purposes for thousands of ***,the main goal of this review is to revisit the neuroprotective potential of some of the most predominant medicinal plants(and one fungus)used in traditional Chinese medicine(TCM),focusing on their proven mechanisms of action and their chemical compositions,to give clues on how they can be useful against neurodegeneration progression.

关键词： Neurodegeneration Alzheimer's disease Parkinson's disease Depression Medicinal plants Oxidative stress Toxicology Clinicaltrials

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Electrooxidation of sulfanilamide and its voltammetric determination in pharmaceutical formulation,human urine and serum on glassy carbon electrode

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Journal of Pharmaceutical Analysis 2018年第1期8卷 55-59页

作者： Bruno R.L.ferraz Tiago Guimaraes Demetrius Profeti Luciene P.R.Profeti Departamento de Biologia Universidade Federal do Espírito SantoAlegre 29.500-000ESBrazil Departamento de Química e Física Universidade Federal do Espírito SantoAlegre 29.500-000ESBrazil

For the first time, sulfanilamide(SFD) was determined in otologic solution, human urine and serum by electroanalytical techniques on glassy carbon electrode(GCE). The cyclic voltammetry(CV) experiments showed an irreversible oxidation peak at t 1.06 V in 0.1 mol/L BRBS(p H ? 2.0) at 50 m V/s. Different voltammetric scan rates(from 10 to 250 m V/s) suggested that the oxidation of SFD on the GCE was a diffusioncontrolled process. Square-wave voltammetry(SWV) method under optimized conditions showed a linear response to SFD from 5.0 to 74.7 μmol/L(R ? 0.999) with detection and quantification limits of 0.92 and3.10 μmol/L, respectively. The developed SWV method showed better results for detection limit and linear range than the chronoamperometry method. It has been successfully applied to determine SFD concentration in pharmaceutical formulation, human urine and serum samples with recovery close to 100%.

关键词： Square-wave voltammetry Sulfanilamide Glassy carbon electrode Biological fluids

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