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Use of simulated sunlight radiation and hydrogen peroxide in azithromycin removal from aqueous solutions:Optimization&mineralization analysis

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Emerging Contaminants 2020年第1期6卷 53-61页

作者： Pablo Andres Cano marcela jaramillo-baquero Henry Zúniga-Benítez Yudy A.Londono Gustavo A.Penuela Facultad de Ingeniería Tecnologico de Antioquia Institucion UniversitariaCalle 78B#72A-220MedellínColombia Departamento de Ingeniería Química Facultad de IngenieríaUniversidad de Antioquia UdeACalle 70#52-21MedellínColombia Grupo GDCON Facultad de IngenieríaSede de Investigacion Universitaria(SIU)Universidad de Antioquia UdeACalle 70#52-21MedellínColombia

Azithromycin(AZT)is a broad-spectrum antibiotic from the group of macrolides that acts against several Gram-positive and Gram-negative bacteria,which has promoted its use in the treatment of different respiratory and sexually transmitted ***,its presence in environmental matrices and in the effluents of conventional wastewater treatment plants has been evidenced in recent years,which reflects the need to develop new treatment alternatives that allow its total removal and minimize the eventual adverse effects,selection of resistant bacterial strains,associated with its presence in water *** sunlight radiation and H2O2 were used to remove AZT from water assessing the effects of operational parameters like the solution initial pH and the peroxide *** indicate that hydroxyl free radical is the main responsible for pollutant removal but acidic solution conditions and larger H2O2 doses negatively affect OHgeneration under the evaluated experimental *** removal was almost complete after 120 min of *** addition,reduction of the organic carbon content in the treated samples was^50.0%;and a significant increase of nitrates concentration in solution was evidenced.

关键词： Advanced oxidation Antibiotics Azithromycin Hydrogen peroxide Sunlight Wastewater treatment

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Effectiveness of an Secondary Prevention Program in Chronic Kidney Disease

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Open Journal of Nephrology 2013年第3期3卷 139-147页

作者： Carlos Enrique Yepes Delgado Yanett marcela Montoya jaramillo Beatriz Elena Orrego Orozco Paulina Bernal Ramírez Luz Denise González José Miguel Abad Echeverri María Patricia Arbeláez Montoya University of Antioquia Hospital Pablo Tobón Uribe EPS SURA Medellín Colombia

Background: There are many programs which focus on late-stage chronic kidney disease (CKD), and it is considered that further evidence needs to be generated regarding the effectiveness of the programs used before renal replacement therapy. Study Design: A cohort study. Settings & Participants: Patients over 15 years of age who had been diagnosed with CKD according to the KDOQI (Kidney Disease Outcomes Quality Initiative) guidelines and who had undergone conventional treatment (CT) or a renal protection program (RPP). These were patients of two Colombian health insurance companies. Predictors: Age, sex, marital status, comorbidities, CKD stage, and clinical indicators. Outcomes: First CKD progression, and need for renal replacement therapy (RRT). Measures: Clinical marker. Results: The RPP is structurally and functionally different from the CT. It offers the interdisciplinary management of patients, a greater number of medical appointments, and patients start to receive treatment at younger ages and at earlier stages of their condition. The clinical markers of the patients following the RPP are within adequate ranges, and their renal function is less impaired, despite the differences in basal conditions. Upon finishing the study, we found that patients who received CT had a higher risk of receiving nephrotoxic drugs and not receiving nephroprotective drugs. The explanatory variables for the first progression were age, stage, history of dyslipidemia, and hemoglobin, potassium, and albumin levels. These variables, together with glycemia levels were also valid for RRT, except for history of dyslipidemia, as it was not significant. Upon adjusting for the explanatory variables, it was found that belonging to the RPP and attending more appointments had a protective effect in the process of controlling renal damage. Limitations: A possible selection bias. Conclusions: Belonging to a structured renal protection program is an effective way to keeping the clinical markers asso

关键词： Chronic Kidney Disease Renal Protection Program Effectiveness Clinical Markers Progression of Renal Damage Renal Replacement Program

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