检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

蛋白酶和盐酸分离牦牛绒中黑色素的研究

纺织学报 2001年第6期22卷 348-351页

作者：阎克路宋心远 K.schaefer H.Hoecker 东华大学上海200051 Wool Research Institute

采用木瓜蛋白酶、盐酸搅拌和盐酸静置的方法，从牦牛绒中分离出黑色素。研究牦牛绒中黑色素的物理和化学性能；并对三种分离方法作了比较。

关键词：酶分离盐酸分离牦牛绒黑色素漂白

在线全文

学校读者我要写书评

暂无评论

牦牛绒选择性漂白工艺的研究

纺织学报 2002年第1期23卷 7-9页

作者：阎克路宋心远 K.schaefer H.Hoecker 东华大学上海200051 WoolResearch Institute

研究牦牛绒选择性漂白工艺中不同预处理条件对牦牛绒吸铁量的影响,提出最佳预处理工艺条件;研制新型清洗工艺,可较大程度降低漂白后纤维的损伤和改善手感。

关键词：牦牛绒选择性漂白工艺前处理吸铁量清洗工艺纤维损伤

Tuberculosis in kidney transplant recipients:A case series

在线全文

学校读者我要写书评

暂无评论

World Journal of Transplantation 2017年第3期7卷 213-221页

作者： Manish Anand Ekta Nayyar Beatrice Concepcion Megha Salani Heidi schaefer Department of Medicine Division of NephrologyUniversity of Cincinnati Trihealth Infectious Disease Good Samaritan Hospital De-partment of Medicine Division of NephrologyVanderbilt University

Solid organ transplant recipients have an elevated risk of tuberculosis(TB) with high mortality. Data about TB in this population in the United States is sparse. We present four cases of active tuberculosis in kidney transplant recipients at our center. All patients had possible TB exposure prior to transplant and all were diagnosed with active TB within the first year of transplant. Disseminated TB was seen in half of the patients with extra-pulmonary TB being more common affecting lymph nodes, pericardium, and the kidney allograft. Delay in diagnosis from onset of symptoms ranged from fifteen days to two months. Two patients died from TB. TB is a largely preventable and curable disease. However, challenges remain in the diagnosis due to most recipients presenting with atypical symptoms. Physicians should maintain a high degree of suspicion for TB to promptly diagnose and treat posttransplant thereby minimizing complications. A review of the literature including the epidemiology, pathogenesis, clinical presentation, diagnosis and treatment options are discussed.

关键词： Mycobacterium tuberculosis Kidney transplant Disseminated disease Tuberculosis

Structures and electronic properties of AUn-1Cu and AUn （n ≤ 9） clusters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2007年第6期16卷 1660-1664页

作者：王红艳李喜波唐永建 R.Bruce King Henry F.schaefer III Institute of Atomic and Molecular Physics Sichuan University Chengdu 610065 China Research Center of Laser Fusion China Academy of Engineering Physical Mianyang 621900 China Department of Chemistry and Center for Computational Chemistry University of Georgia Athens Georgia 30602 USA

A systematic study on the structure and electronic properties of gold clusters doped each with one copper atom has been performed using the density functional theory. The average bond lengths in the Aun-1Cu （n ≤ 9） bimetallic clusters are shorter than those in the corresponding pure gold clusters. The ionization potentials of the bimetallic clusters Aun-1Cu （n 〈 9） are larger than those of the corresponding homoatomic gold clusters except for Aus. The energy gaps of the Au-Cu binary clusters are narrower than those of the Aun clusters except AuCu and Au3Cu. No obvious even-odd effect exists in the variations of the electron affinities and ionization potentials for the Aun-1Cu （n ≤ 9） clusters, which is in contrast to the case of gold clusters Aun.

关键词： Au-Cu bimetallic cluster equilibrium geometry bond energy HOMO-LUMO gap

Arbuscular Mycorrhiza and Sustainable Agriculture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Circular Agricultural Systems 2021年第1期1卷 39-45页

作者： Douglas A.schaefer Heng Gui Peter E.Mortimer Jianchu Xu Centre for Mountain Futures(CMF) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina CAS Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanChina

Arbuscular mycorrhizal fungi(AMF)provide benefits to most crop species via enhanced nutrient uptake,increased drought and abiotic stress resistance,and reduced effects of pathogens and *** remains unclear regarding the specific mechanisms influencing these processes,and the critical roles of AMF are often overlooked in planning agroecological *** is growing consensus,however,around the important roles AMF play in improving plant resilience and crop yield while also enhancing the functioning of soil microbial *** practices across all scales complicate the successful integration of AMF in agroecological *** symbioses with crops are passive,or stimulated by incorporation of crop wastes in soil,soil inoculation with AMF spores,or the planting inoculated of *** we suggest that AMF can have highest beneficial impacts in areas with low levels of agrochemical *** argue that areas with intensive agrochemical inputs can also be made more sustainable with AMF enhancements.

关键词： soil crops planting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

游戏的力量

作者： (美)Charles E. schaefer，(美)Donna Cangelosi

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

生产聚丙烯短纤和薄膜带的挤压机生产线

国外纺织技术（化纤．染整．环境保护分册） 1994年第4期 20-25页

作者： Klaus schaefer 德国Barmag公司

一、简介聚丙烯在聚合物的家族中占有直越来越重要的地位,近十年来,由于聚合物和加工技术的不断发展使得聚丙烯与其它人造和天然纤维相比,处于有利的竞争地位,出于经济原因,以及聚丙烯的下列特性正在不断地开发出新的应用领域:易于加... 详细信息

一、简介聚丙烯在聚合物的家族中占有直越来越重要的地位,近十年来,由于聚合物和加工技术的不断发展使得聚丙烯与其它人造和天然纤维相比,处于有利的竞争地位,出于经济原因,以及聚丙烯的下列特性正在不断地开发出新的应用领域:易于加工、易于熔化染色、高绝缘性、不吸湿性、优良的吸油性以及其它许多特性。

关键词：聚丙烯短纤维薄膜带挤压机生产线

Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第45期22卷 9954-9965页

作者： Esperance AK schaefer James Meixiong Christina Mark Amy Deik Daniel L Motola Dahlene Fusco Andrew Yang Cynthia Brisac Shadi Salloum Wenyu Lin Clary B Clish Lee F Peng Raymond T Chung Gastrointestinal Unit Massachusetts General Hospital Bossston MA 02114 United States Department of Medicine Harvard Medical School Bossston MA 02114 United States both of the Broad Institute of Harvard and M.I.T. Cambridge MA 02115 United States Temple University Health System Cambridge MA 02142 United States

AIM To characterize the role of apolipoprotein B100(apoB 100) in hepatitis C viral(HCV) infection. METHODS In this study, we utilize a gene editing tool, transcription activator-like effector nucleases(TALENs), to generate human hepatoma cells with a stable genetic deletion of APOB to assess of apoB in HCV. Using infectious cell culture-competent HCV, viral pseudoparticles, replicon models, and lipidomic analysis we determined the contribution of apoB to each step of the viral lifecycle. We further studied the effect of mipomersen, an FDAapproved antisense inhibitor of apoB 100, on HCV using in vitro cell-culture competent HCV and determined itsimpact on viral infectivity with the TCID50 method. RESULTS We found that apo B100 is indispensable for HCV infection. Using the JFH-1 fully infectious cell-culture competent virus in Huh 7 hepatoma cells with TALENmediated gene deletion of apoB(APOB KO), we found a significant reduction in HCV RNA and protein levels following infection. Pseudoparticle and replicon models demonstrated that apo B did not play a role in HCV entry or replication. However, the virus produced by APOB KO cells had significantly diminished infectivity as measured by the TCID-50 method compared to wildtype virus. Lipidomic analysis demonstrated that these virions have a fundamentally altered lipidome, with complete depletion of cholesterol esters. We further demonstrate that inhibition of apoB using mipomersen, an FDA-approved anti-sense oligonucleotide, results in a potent anti-HCV effect and significantly reduces the infectivity of the virus. CONCLUSION Apo B is required for the generation of fully infectious HCV virions, and inhibition of apo B with mipomersen blocks HCV. Targeting lipid metabolic pathways to impair viral infectivity represents a novel host targeted strategy to inhibit HCV.

关键词： Apolipoprotein Lipid Hepatitis C virus Gene silencing Viral replication

COVID-19疫情期间成都市地面臭氧污染特征及气象成因分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

环境科学学报 2021年第10期41卷 4200-4211页

作者：祁宏张小玲康平 Klaus schaefer 向卫国邓中慈卢宁生雷雨成都信息工程大学大气科学学院高原大气与环境四川省重点实验室成都610225 成都平原城市气象与环境四川省野外科学观测研究站成都610225

受COVID-19疫情影响,我国各地采取了一系列封锁管控措施,由此导致大气污染物排放强度降低.本文以成都市为例,分析了2020年上半年的气象条件和大气污染浓度特征,并重点对臭氧浓度变化及同期对比结果进行了细致分析.结果表明:(1)与2019年... 详细信息

受COVID-19疫情影响,我国各地采取了一系列封锁管控措施,由此导致大气污染物排放强度降低.本文以成都市为例,分析了2020年上半年的气象条件和大气污染浓度特征,并重点对臭氧浓度变化及同期对比结果进行了细致分析.结果表明:(1)与2019年同期相比,除O_(3)外的5种污染物(NO_(2)、CO、SO_(2)、PM_(10)、PM_(2.5))浓度均降低,降幅分别为13.60%、8.96%、6.30%、4.56%、1.80%,而O_(3)浓度却异常升高,升幅最大值分别出现在2月(35.1%)和5月(36.1%).(2)2020年上半年,O_(3)浓度高值出现时间较2015—2019年提前,气象条件较有利于臭氧的生成.100 hPa和500 hPa位势高度为正距平,气温、日照时数较往年升高,相对湿度和降水量下降,以静小风为主.(3)2020年4月25日—5月6日臭氧污染持续时间长,主要是由于复工复产导致臭氧前体物排放增加,以及稳定的天气形势,使成都长时间处于高温(>30℃)、低湿(40%~60%)、静小风(1.3 m·s^(-1))等不利扩散的气象条件下.气团后向轨迹和污染潜在源区表明研究区受到来自成都偏东一带及川南地区高污染气团短距离输送的影响.

关键词：成都市新冠疫情气象条件后向轨迹潜在源分析