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Spinal Analgesia with Intrathecal Morphine versus Conventional Analgesia after Laparoscopic Colectomy: A Retrospective Cohort Study

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Open Journal of Anesthesiology 2024年第7期14卷 159-174页

作者： Lionel Diyamona Manon Colin marc Léone Laurent Zieleskiewicz Joseph Nsiala Wilfrid Mbombo Rachel Mbala Bruno Pastene Chris Nsituavibidila Dan Kankonde Gracia Likinda Jean Claude Mubenga Khazy Anga Noelly Mukuna Christel Isengingo Department of Anaesthesia and Intensive Care University Clinics of Kinshasa University of Kinshasa Kinshasa Democratic Republic of the Congo Department of Anaesthesia and Intensive Care Marseilles Nord Hospital Marseille France General Hospital of Kinshasa ex Mama Yemo Kinshasa Democratic Republic of the Congo Department of Anaesthesia and Intensive Care Monkole Hospital Centre Kinshasa Democratic Republic of the Congo

Objective: Postoperative pain (POP) following abdominal surgery can vary from a few hours to several days. This acute, unrelieved pain can become chronic, requiring patients to take analgesics on an almost daily basis for comfort. Analgesia using general opioids has many side effects and intrathecal morphine is a good alternative. This study was conducted to evaluate the efficacy of intrathecal morphine (ITM) versus conventional analgesia in the management of postoperative pain in colectomy performed by laparoscopic surgery. Methods: Cohort study conducted at the Hôpital Nord in Marseille, from 01 January to 31 July 2021 in patients aged at least 18 years undergoing anaesthesia for scheduled colectomy by laparoscopic surgery. The primary endpoint was postoperative pain intensity and the secondary endpoints were morphine consumption, treatment side effects and length of hospital stay. Statistical analysis was performed using XLSTAT software. Results: We included 193 patients: 131 in the control group (conventional analgesia) and 62 in the ITM group. We observed: a significant decrease in pain (assessed by numerical scale) in favour of the ITM group in the post-anaesthetic care room, i.e. 3 (±4) vs 1 (±2), p 0 and H2: 2 (±2) vs. 1 (±2);p Conclusion: These results suggest that intrathecal morphine (ITM) in laparoscopic colectomy provides effective postoperative analgesia with low morphine consumption, and a reduction in morphine side-effects compared with conventional analgesia.

关键词： Intrathecal Morphine Colectomy Laparoscopy Conventional Analgesia

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Neural prostheses for restoring functions lost after spinal cord injury

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Neural Regeneration Research 2015年第10期10卷 1594-1595页

作者： marc Fakhoury Department of Neurosciences Faculty of Medicine University of Montreal

Spinal cord injury（SCI）is a debilitating condition that affects more than 2.5 million individuals worldwide（Thuret et al.,2006）.In addition to its devastating effects on the individual,this disease is a heavy burden to the society in terms of health care costs, which are estimated in billions of dollars annually in most developed countries （Cadotte and Fehlings, 2011）.

关键词： more SCI Neural prostheses for restoring functions lost after spinal cord injury

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Bacteriological Profile of Infections Encountered in a Pneumology Service in a Moderate-Income Country [Pneumology Department of CHU Cocody (Côte d’Ivoire)]

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Open Journal of Respiratory Diseases 2024年第1期14卷 1-11页

作者： Brou Jean marcel Ahui Alitonde Eudoxie Djegbeton Alima Kone marc-Olivier Koffi Kouame Clarisse Elogne Mobio Nancy Hermine Benjamin Kouraogo Erick Akouatia Constante Virginie Brou-Gode Kigninlman Horo Boko Alexandre Kouassi Ngoran Koffi Pneumology Service Teaching Hospital of Cocody Abidjan C&#244te d’Ivoire Medical School of Abidjan University Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire Pasteur Institute of Cô te d’Ivoire Abidjan C&#244te d’Ivoire

Introduction: Infections represent a real public health problem aggravating the morbidity and mortality of hospitalized patients. Methods: This was a retrospective study with descriptive purposes over a period of 05 years, in the Pneumology Department of the University Hospital of Cocody. Results: The average age in our population was 42 years. We observed a male predo- minance of 64.5%, with a sex ratio of 1.8. Medical history was dominated by HIV infection (23.5%), followed by tuberculosis (15.6%). Concerning lifestyle, smoking was found in 38% of cases. Symptoms progressed chronically in 80% of cases. An infectious syndrome was found in 75% of cases. Microbial culture was positive in 42% of cases. Pseudomonas aeruginosa and Klebsiella pneumoniae were encountered in 26.4% of cases each, followed by Echerichia coli in 10.4% of cases. Klebsiella pneumoniae in the first three years topped the list, but gradually. Pseudomonas aeruginosa maintained its leadership over the last three years. Pseudomonas aeruginosa isolates expressed a resistance rate of 9.8% to ceftazidime and 8.1% to imipenem;to aztreonam (36%), ticarcillin (33.3%) and levofloxacin. These strains were susceptible to fosfomycin (100%), mero- penem (96.6%) and amikacin (96%). For isolated strains of Entero- bacteria- ceae, resistance was observed about ticarcillin (83.3%) and amoxicillin clavula- nic acid (71.2%). Streptococcaceae showed resistance to tetracycline (69.2%) and erythromycin (50%). Over the years there has been an increase in re- sistance to amoxicillin-clavulanic acid ceftriaxone. The death rate was 14%. Conclusion: The bacterial profile of infections is dominated by germs respon- sible for nosocomial infection with significant mortality.

关键词： Bacterial Pleural Pneumonia Nosocomial Infection Sub-Saharan Africa Antibiotic Therapy

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Impact of pre-existing cardiometabolic diseases on metastatic cancer stage at diagnosis:a prospective multinational cohort study

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Cancer Communications 2024年第5期44卷 593-597页

作者： Anna Jansana Aviane Auguste Marina Kvaskoff Agnès Fournier Emma Fontvieille Laia Peruchet-Noray Carine Biessy Reynalda Cordova Kristina Elin Nielsen Petersen Anne Tjoneland Verena Katzke Rudolf Kaaks Fulvio Ricceri Salvatore Panico Paolo Contiero Maria-Jose Sánchez Jesus Castilla Marta Crous-Bou Alicia Heath Elom Kouassivi Aglago Elisabete Weiderpass marc James Gunter Pietro Ferrari Elio Riboli Vivian Viallon Heinz Freisling International Agency for Research on Cancer(IARC-WHO) LyonFrance Paris-Saclay University University of Versailles-Saint-Quentin-en-YvelineUniversity Paris-SudFrench National Institute for Health and Medical Research(Inserm)Gustave Roussy“Exposome and Heredity”TeamCESPVillejuifFrance Department of Nutritional Sciences University of ViennaViennaAustria Danish Cancer Society Research Center CopenhagenDenmark Department of Public Health University of CopenhagenCopenhagenDenmark Division of Cancer Epidemiology German Cancer Research CentreHeidelbergGermany Department of Clinical and Biological Sciences University of TurinTurinItaly Unit of Epidemiology Regional Health Service ASL TO3GrugliascoTurinItaly Department of Clinical Medicine and Surgery Federico II UniversityNaplesItaly Environmental Epidemiology Unit Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)-Istituto Nazionale dei TumoriMilanItaly Cancer Registry of Granada Institute for Biosanitary Research of Granada(ibs.GRANADA)GranadaSpain Epidemiology and Control of Chronic Diseases Group Epidemiology and Public Health Networking Biomedical Research CentreMadridSpain Navarra Public Health Institute PamplonaSpain Unit of Nutrition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of Oncology(ICO)-Bellvitge Biomedical Research Institute(IDIBELL)L’Hospitalet de LlobregatBarcelonaSpain Department of Epidemiology Harvard Tseng-Hsi Chan School of Public HealthBostonMassachusettsUSA Department of Epidemiology and Biostatistics School of Public HealthImperial College LondonSt Mary’s CampusNorfolk PlaceLondonUK

Owing to shared risk factors between cardiometabolic diseases(CMDs)and cancer,coupled with population aging,the lifetime risk of an individual developing cancer after a CMD is ***,biological mechanisms such as insulin resistance or inflammation may not only predispose individuals withCMDto an elevated risk of certain types of cancer but also to a diagnosis of cancer at an advanced stage[1,2].

关键词： diagnosis diseases cancer

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Generalized Backward Doubly Stochastic Differential Equations Driven by Lévy Processes with Continuous Coefficients

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Acta Mathematica Sinica,English Series 2012年第10期28卷 2011-2020页

作者： Auguste AMAN Jean marc OWO UFR de Mathématiques et Informatique Université de Cocody

A new class of generalized backward doubly stochastic differential equations （GBDSDEs in short） driven by Teugels martingales associated with Levy process are investigated. We establish a comparison theorem which al... 详细信息

关键词： Backward doubly stochastic differential equations L@vy processes Teugels martingales comparison theorem continuous and linear growth conditions

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Functionally Graded Dual-nanoparticulate-reinforced Aluminium Matrix Bulk Materials Fabricated by Spark Plasma Sintering

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Journal of Materials Science & Technology 2014年第8期30卷 736-742页

作者： Hansang Kwon marc Leparoux Akira Kawasaki Department of Materials System Engineering Pukyong National University365 Sinsenro608-759 BusanKorea Empa Swiss Federal Laboratories for Materials Science and TechnologyAdvanced Materials ProcessingFeuerwerkerstrasse 39CH-3602 ThunSwitzerland Department of Materials Processing Engineering Graduate School of EngineeringTohoku University980-8579 SendaiJapan

Functionally graded（FG） carbon nanotubes（CNT） and nano-silicon carbide（nSiC） reinforced aluminium（Al）matrix composites have been successfully fabricated using high-energy ball milling followed by solid-state spark plasma sintering *** CNTs were well-dispersed in the Al particles using the nSiC as a solid mixing *** different types of multi-walled CNTs were used to add different amounts of CNTs in the same *** ball milled Al—CNT—nSiC and Al—CNT powder mixtures were fully densified and demonstrated good adhesion with no serious microcracks and pores within an FG multilayer *** layer contained different amounts of the CNTs,and the nSiC additions showed different microstructures and *** is possible to control the characteristics of the FG multilayer composite through the efficient design of an Al—CNT—nSiC gradient *** concept offers a feasible approach for fabricating the dualnanoparticulate-reinforced Al matrix nanocomposites and can be applied to other scenarios such as polymer and ceramic systems.

关键词： Carbon nanotubes(CNT) Silicon carbide High-energy ball milling Spark plasma sintering(SPS) Functionally graded materials(FGM)

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Alien calculus and non perturbative effectsin Quantum Field Theory

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Frontiers of physics 2016年第6期11卷 31-34页

作者： marc P. Bellon Sorbonne Universites UPMC Univ Paris 06 UMR 7589 LPTHE 75005 Paris France CNRS UMR 7589 LPTHE 75005 Paris France

In many domains of physics, methods for dealing with non-perturbative aspects are required. Here, I want to argue that a good approach for this is to work on the Borel transforms of the quantities of interest, the singularities of which give non-perturbative contributions. These singularities in many cases can be largely determined by using the alien calculus developed by Jean Écalle. My main example will be the two point function of a massless theory given as a solution of a renormalization group equation.

关键词： Schwinger–Dyson equations, series resommation, alien calculus

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Wear Behavior of a Bio-inspired Bearing for off-center Loads

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Journal of Bionic Engineering 2020年第6期17卷 1251-1262页

作者： Delphine Sysaykeo Jean-marc Linares Emmanuel Mermoz Alix-Marseile Universite CNRSCentre National de la Recherche ScientifiqueISMInstitut des Sciences du MouvementMarseille 13009France Advanced concepts and Dynamic systems architecture department Airbus HelicoptersAeroport International Marseille ProvenceMarignane 13700France

Misalignment is one of the most common causes of wear in bush *** improvements have been proposed by many ***,it did not efficiently reduce the *** geometrical designs sometimes reach their *** this reason,a bio-inspired design is proposed to solve the *** this article,a bio-inspired bearing suited to misalignment was tested and compared to a classical bush *** contact pressures of both bearings were compared with static Finite Element(FE)simulations for off-center *** to the complex shape of the involved contact,the performances of both bearings were also studied over *** wear behaviors were predicted with a numerical *** methodologies emplaced to simulate the wear were described in this ***,the wear coefficient determination obtained by experimental testing was *** pressure value,the contact zone and the wear depth were compared and *** wear results for the classical bearing are in accordance with the *** simulations show a deeper wear on the classical bush bearing than on the bio-inspired *** leads to a longer period of service life for the bio-inspired bearing.

关键词： biologically inspired design bush bearing wear simulation

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When is a varicocele repair indicated： the dilemma of hypogonadism and erectile dysfunction？

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Asian Journal of Andrology 2016年第2期18卷 213-216,J0004页

作者： Ali A Dabaja marc Goldstein Department of Male Reproductive Medicine Weill Cornell Medical College New York USA Department of Urology Henry Ford Health System Detroit MI USA.

In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain. The surgical treatment of varicocele for hypogonadism is controversial and debated. Recently, multiple reports in the literature have suggested that varicocele is associated with hypogonadism and varicocele repair can increase testosterone levels. Men with hypogonadal symptoms should have at least two serum testosterone levels. Microsurgical varicocelectomy may be beneficial for men with clinically palpable varicoceles with documented hypogonadism. In this review, we summarize the most recent literature linking varicocele to hypogonadism and sexual dysfunction and the impact of repair on serum testosterone levels. We performed a search of the published English literature. The key words used were ＂varicocele and hypogonadism＂ and ＂varicocele surgery and testosterone.＂ We included published studies after 1998. We, also, evaluated the effect of surgery on the changes in the serum testosterone level regardless of the indication for the varicocele repair.

关键词： erectile dysfunction hypogonadism varicocele varicocelectomy

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Microsurgical varicocelectomy： a review

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Asian Journal of Andrology 2013年第1期15卷 56-60页

作者： Akanksha Mehta marc Goldstein Department of Urology and Center for Male Reproductive Medicine and Surgery Weill Cornell Medical College New York NY 10021 USA

Varicocelectomy is the most commonly performed surgical procedure for the treatment of male infertility. Although several different techniques for varicocele repair have been described in the literature, microsurgical varicocelectomy performed through a subinguinal or inguinal incision is recognized as the gold-standard approach for varicocelectomy, due to high success rates with minimal complications. Standard indications for varicocelectomy include palpable varicocele（s）, with one or more abnormal semen parameters, and, for the couple trying to conceive, in the setting of normal or correctable female infertility. However, varicocele repair is often recommended and undertaken for reasons other than infertility, including low serum testosterone, testicular pain, testicular hypotrophy and poor sperm DNA quality. This article reviews the technical aspects of microsurgical varicocelectomy, and its indications in adults and adolescents.

关键词： DNA fragmentation hypogonadism infertility microsurgical varicocelectomy orchalgia varicocele repair

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