检索结果-南通市图书馆

Medical management of urolithiasis: Great efforts and limited progress

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Urology 2024年第2期11卷 149-155页

作者： Victoria Jahrreiss Christian seitz Fahad Quhal Department of Urology Comprehensive Cancer CenterMedical University of ViennaViennaAustria Department of Urology King Fahad Specialist HospitalDammamSaudi Arabia

Objective:To provide a comprehensive review on the existing literature on medical management of urolithiasis.Methods:A thorough literature review was performed using Medline,PubMed/PMC,Embase,and the Cochrane Database of Systematic Reviews up to December 2022 to identify publications on the medical management of urolithiasis.Studies that assessed dietary and pharmacologic management of urolithiasis were reviewed;studies on medical expulsive therapy were not included in this review.Results:Medical management of urolithiasis ranges from the prophylactic management of kidney stone disease to dissolution therapies.While most treatment concepts have been long established,large randomized controlled trials are scarce.Dietary modification and increased fluid intake remain cornerstones in the conservative management of urolithiasis.A major limitation for medical management of urolithiasis is poor patient compliance.Conclusion:Medical management of urolithiasis is more important in patients with recurrent urolithiasis and patients with metabolic abnormalities putting them at higher risk of developing stones.Although medical management can be effective in limiting stone recurrence,medical interventions often fail due to poor compliance.

关键词： Medicalmanagement Medical therapy Urolithiasis Kidneystonedisease

Macular vascularisation changes analysed using OCT angiography after successful rhegmatogenous retinal detachment repair

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2023年第1期16卷 81-87页

作者： Marie Hartmann Alaa Din Abdin Doris Fraenkel Christian Munteanu Berthold seitz Shady Suffo Department of Ophthalmology Saarland University Medical CenterHomburg/Saar 66421Germany

AIM:To analyse the macular vascularisation changes analysed using optical coherence tomography angiography(OCTA)after successful rhegmatogenous retinal detachment(RRD)repair by comparing gas vs silicone oil and macula-on vs macula-off.METHODS:This retrospective data collection included 77 eyes with RRD that underwent pars plana vitrectomy(PPV)and gas or silicone oil tamponade.We performed an OCTA during the postoperative control between 6 and 24mo after the last surgery and evaluated the main parameters measured by OCTA:foveal avascular zone(FAZ)and parafoveolar vascular density(PVD)in the superficial capillary plexus.The patients were divided into four groups:RRD with macular involvement treated with gas tamponade,RRD without macular involvement treated with gas tamponade,RRD with macular involvement treated with silicone oil tamponade and RRD without macular involvement treated with silicone oil tamponade.A one-way ANOVA test combined with post hoc Bonferroni corrections compared FAZ sizes and PVD in all four groups.RESULTS:The FAZ size was statistically significantly larger in eyes with RRD involving the macula than in those not involving it(P=0.005).There was no statistically significant difference in the FAZ sizes of the eyes treated with silicone oil tamponade compared to those treated with gas tamponade(P=0.54).There was no statistically significant difference in the PVD comparing all four groups.CONCLUSION:Despite the known risks associated with silicone oil,our findings suggest that the type of tamponade used during PPV to treat an RRD has no significant effect on the future integrity of the PVD or the size of the FAZ in the superficial capillary plexus as measured by OCTA.

关键词： retina vitrectomy optical coherence tomography angiography

Alcoholic liver disease and hepatitis C:A frequently underestimated combination

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第28期15卷 3462-3471页

作者： Sebastian Mueller Gunda Millonig Helmut K seitz Department of Medicine and Center for Alcohol Research Live Disease and Nutrition Salem Medical Center University of Heidelberg Zeppelinstraβe 11-33 69121 Heidelberg Germany

Alcoholic liver disease(ALD) and hepatitis C virus(HCV) infection represent, either alone or in combination, more than two thirds of all patients with liver disease in the Western world.This review discusses the epidemiology and combined impact of ALD and HCV on the progres sion of liver disease.ALD and HCV affect the progres sion of liver disease to liver cirrhosis and hepatocellular carcinoma(HCC) in a synergistic manner.Thus, the risk for HCC increases f ive times with a daily alcohol con sumption of 80 g;in the presence of HCV it is increased 20fold, and a combination of both risk factors leads to a more than 100fold risk for HCC development.Alcohol consumption also decreases the response to interferon treatment which is probably due to a lack of compliance than a direct effect on HCV replication.Several molecu lar mechanisms are discussed that could explain the synergistic interaction of alcohol and HCV on disease progression.They include modulation of the immune response and apoptosis, increased oxidative stress via induction of CYP2E1 and the hepatic accumulation of iron.Thus, both HCV and alcohol independently cause hepatic iron accumulation in > 50% of patients probably due to suppression of the liversecreted systemic iron hormone hepcidin.A better understanding of hepcidin regulation could help in developing novel therapeutic approaches to treat the chronic disease in the future.For now, it can be generally concluded that HCVinfect ed patients should abstain from alcohol and alcoholicsshould be encouraged to participate in detoxification programs.

关键词：丙型肝炎酒精性肝病

Evaluating metallic artefact of biodegradable magnesium-based implants in magnetic resonance imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2022年第9期7卷 382-391页

作者： Jonathan Espiritu Mostafa Berangi Christina Yiannakou Eduarda Silva Roberto Francischello Andre Kuehne Thoralf Niendorf Soren Konneker Regine Willumeit-Romer Jan-Marten seitz Syntellix AG HannoverGermany MRI.TOOLS GmbH BerlinGermany Charit´e-Universitatsmedizin Berlin Corporate Member of Freie Universitat Berlin and Humboldt Universitat zu BerlinBerlinGermany Berlin Ultrahigh Field Facility(B.U.F.F.) Max-Delbrueck Center for Molecular Medicine in the Helmholtz AssociationBerlinGermany Hannover Medical School HannoverGermany Institute of Clinical Physiology National Research CouncilPisaItaly Chemistry and Industrial Chemistry Department Universita di PisaVia Moruzzi 13PisaItaly Fondazione Toscana Gabriele Monasterio Via Moruzzi 1PisaItaly Institute for Materials Research Helmholtz Zentrum HereonGeesthachtGermany

Magnesium(Mg)implants have shown to cause image artefacts or distortions in magnetic resonance imaging(MRI).Yet,there is a lack of information on how the degradation of Mg-based implants influences the image quality of MRI examinations.In this study,Mg-based implants are analysed in vitro,ex vivo,and in the clinical setting for various magnetic field strengths with the aim to quantify metallic artefact behaviour.In vitro corroded Mg-based screws and a titanium(Ti)equivalent were imaged according to the ASTM F2119.Mg-based and Ti pins were also implanted into rat femurs for different time points and scanned to provide insights on the influence of soft and hard tissue on metallic artefact.Additionally,MRI data of patients with scaphoid fractures treated with CE-approved Mg-based compression screws(MAGNEZIX®)were analysed at various time points post-surgery.The artefact production of the Mg-based material decreased as implant material degraded in all settings.The worst-case imaging scenario was determined to be when the imaging plane was selected to be perpendicular to the implant axis.Moreover,the Mg-based implant outperformed the Ti equivalent in all experiments by producing lower metallic artefact(p<0.05).This investigation demonstrates that Mg-based implants generate significantly lower metallic distortion in MRI when compared to Ti.Our positive findings suggest and support further research into the application of Mg-based implants including post-operative care facilitated by MRI monitoring of degradation kinetics and bone/tissue healing processes.

关键词： Magnetic resonance imaging Magnesium Biodegradable implants Medical imaging Translational medicine

Detailing the influence of PEO-coated biodegradable Mg-based implants on the lacuno-canalicular network in sheep bone:A pilot study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2023年第8期26卷 14-23页

作者： Jonathan Espiritu Sandra Sefa Hanna Cwieka Imke Greving Silja Flenner Regine Willumeit-Römer Jan-Marten seitz Berit Zeller-Plumhoff Syntellix AG HannoverGermany Institute of Metallic Biomaterials Helmholtz-Zentrum HereonGeesthachtGermany Institute of Materials Physics Helmholtz-Zentrum HereonGeesthachtGermany

An increasing prevalence of bone-related injuries and aging geriatric populations continue to drive the orthopaedic implant market.A hierarchical analysis of bone remodelling after material implantation is necessary to better understand the relationship between implant and bone.Osteocytes,which are housed and communicate through the lacuno-canalicular network(LCN),are integral to bone health and remodelling processes.Therefore,it is essential to examine the framework of the LCN in response to implant materials or surface treatments.Biodegradable materials offer an alternative solution to permanent implants,which may require revision or removal surgeries.Magnesium alloys have resurfaced as promising materials due to their bone-like properties and safe degradation in vivo.To further tailor their degradation capabilities,surface treatments such as plasma electrolytic oxidation(PEO)have demonstrated to slow degradation.For the first time,the influence of a biodegradable material on the LCN is investigated by means of non-destructive 3D imaging.In this pilot study,we hypothesize noticeable variations in the LCN caused by altered chemical stimuli introduced by the PEO-coating.Utilising synchrotron-based transmission X-ray microscopy,we have characterised morphological LCN differences around uncoated and PEO-coated WE43 screws implanted into sheep bone.Bone specimens were explanted after 4,8,and 12 weeks and regions near the implant surface were prepared for imaging.Findings from this investigation indicate that the slower degradation of PEO-coated WE43 induces healthier lacunar shapes within the LCN.However,the stimuli perceived by the uncoated material with higher degradation rates induces a greater connected LCN better prepared for bone disturbance.

关键词： Nanotomography Lacuno-canalicular network Bone Magnesium Biodegradable implants

Radiofrequency induced heating of biodegradable orthopaedic screw implants during magnetic resonance imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2023年第7期25卷 86-94页

作者： Jonathan Espiritu Mostafa Berangi Hanna Cwieka Kamila Iskhakova Andre Kuehne D.C.Florian Wieland Berit Zeller-Plumhoff Thoralf Niendorf Regine Willumeit-Römer Jan-Marten seitz Syntellix AG HannoverGermany MRI.TOOLS GmbH BerlinGermany Charité-Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt Universität zu BerlinBerlinGermany Berlin Ultrahigh Field Facility(B.U.F.F.) Max-Delbrueck Center for Molecular Medicine in the Helmholtz AssociationBerlinGermany Institute of Metallic Biomaterials Helmholtz Zentrum HereonGeesthachtGermany

Magnesium(Mg)-based implants have re-emerged in orthopaedic surgery as an alternative to permanent implants.Literature reveals little information on how the degradation of biodegradable implants may introduce safety implications for patient follow-up using medical imaging.Magnetic resonance imaging(MRI)benefits post-surgery monitoring of bone healing and implantation sites.Previous studies demonstrated radiofrequency(RF)heating of permanent implants caused by electromagnetic fields used in MRI.Our investigation is the first to report the effect of the degradation layer on RF-induced heating of biodegradable orthopaedic implants.WE43 orthopaedic compression screws underwent in vitro degradation.Imaging techniques were applied to assess the corrosion process and the material composition of the degraded screws.Temperature measurements were performed to quantify implant heating with respect to the degradation layer.For comparison,a commercial titanium implant screw was used.Strongest RF induced heating was observed for non-degraded WE43 screw samples.Implant heating had shown to decrease with the formation of the degradation layer.No statistical differences were observed for heating of the non-degraded WE43 material and the titanium equivalent.The highest risk of implant RF heating is most pronounced for Mg-based screws prior to degradation.Amendment to industry standards for MRI safety assessment is warranted to include biodegradable materials.

关键词： Biodegradable implants Magnesium Medical imaging Magnetic resonance imaging Patient safety

The current performance of biodegradable magnesium-based implants in magnetic resonance imaging:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2021年第12期6卷 4360-4367页

作者： Jonathan Espiritu Martin Meier Jan-Marten seitz Syntellix AG HannoverGermany Hannover Medical School HannoverGermany

Magnesium-based implants are re-emerging as a substantial amendment to standard orthopaedic implants.A brief introduction of magnesium(Mg)as a biodegradable material and basic magnetic resonance imaging(MRI)principles are discussed.This review aims to highlight the current performance of these implants during examinations with MRI.We also aim to summarise comparisons between Mg-based implants with current standards to emphasise the promotion of biodegradable implants in clinical practice.A comprehensive search of current literature on Mg-based implants and the utilisation of MRI in the studies was performed.Additionally,recorded artefact behaviour of Mg-based implants during MRI was investigated.A total of nine studies were included in which MRI was employed to image Mg-based implants.Of those studies,four of the nine discuss artefact production caused by the implants.MRI successfully imaged regions of interest over all and produced fewer artefacts than other materials used in the studies.MRI was employed in contrast angiography,bone growth observation,bone infection healing,and blood perfusion.Imaging capabilities of an implant material are vital to translating products into clinical application.Positive findings presented in this review suggest and support the use of Mg-based implants due to their successful visual compatibility with MRI techniques.

关键词： Magnetic resonance imaging Magnesium Biodegradable implants Medical imaging Patient safety

Good Outcome after More Than a Million Troponin in Serum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Case Reports in Clinical Medicine 2022年第1期11卷 25-30页

作者： Mohamed Elbayomi Timo seitz Michael Weyand Department of Cardiac Surgery Friedrich-Alexander-University Erlangen-Nuremberg Erlangen Germany

A troponin in serum of more than one Million in vivo is rare insult. We report a case of 85-year-old woman who was transferred to our institution because of acute ST elevated myocardial infarction and the troponin level reached a peak of 1,032,904.2 pg/ml. She was discharged with highly reduced left ventricular function, however in the three months follow up after a coronary bypass operation she completely was free from heart failure symptoms and echocardiography showed a totally normal function of both ventricles. This case study highlights that the initial serum troponin in acute settings can mislead the long-term prognosis and gives prominence to the expeditious myocardial revascularization.

关键词： Cardiac Troponin Coronary Bypass Operation Heart Lung Machine

Believing processes during the COVID-19 pandemic in individuals with bipolar disorder:An exploratory study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2022年第7期12卷 929-943页

作者： Sophie Tietz Jolana Wagner-Skacel Hans-Ferdinand Angel Michaela Ratzenhofer Frederike T Fellendorf Eva Fleischmann Christof Körner Eva Z Reininghaus Rüdiger J seitz Nina Dalkner Institute of Psychology University of GrazGraz 8010Austria Department of Psychiatry and Psychotherapeutic Medicine Medical University of GrazGraz 8036Austria Department of Medical Psychology and Psychotherapy Medical University of GrazGraz 8036Austria Department of Catechetics and Religious Education University of GrazGraz 8010Austria Department of Neurology Centre of Neurology and Neuropsychiatry Heinrich-Heine-University DüsseldorfMedical FacultyDüsseldorf D-40629Germany

BACKGROUND Believing or“credition”refers to psychological processes that integrate the cognitions and emotions that influence our behavior.In the credition model by Angel and seitz,four parameters are postulated:proposition,certainty,emotion and mightiness.It is assumed that believing processes are influenced by both the individual as well as socio-cultural factors and external circumstances.External or environmental circumstances can include threatening situations such as the ongoing pandemic.It has been hypothesized that believing processes related to the pandemic differ between individuals with bipolar disorder(BD)and healthy controls(HC).AIM To investigate credition in individuals with BD during the coronavirus disease 2019(COVID-19)pandemic.METHODS Psychiatrically stable individuals with BD(n=52)and age-and sex matched HC(n=52)participated in an online survey during the first lockdown of the COVID-19 pandemic.The survey took place between April 9^(th) and June 4^(th),2020,in Austria.Participants completed the Brief Symptom Inventory-18,the Beck Depression Inventory-Ⅱ,the Altman Self-Rating Mania Scale,the Pittsburgh Sleep Quality Index and a dedicated Believing Questionnaire assessing four parameters of credition(proposition,certainty,emotion and mightiness).The MAXQDA software was used to analyze the qualitative data.Statistical analyses included analyses of variance,a multivariate analysis of variance and a multivariate analysis of co-variance.RESULTS Individuals with BD reported significantly more negative propositions[F(1,102)=8.89,P=0.004,η2 p=0.08]and negative emotions[Welch´s F(1,82.46)=18.23,P<0.001,η2 p=0.18],while HC showed significantly more positive propositions[F(1,102)=7.78,P=0.006,η2 p=0.07]and emotions[F(1,102)=14.31,P<0.001,η2 p=0.12].In addition,individuals with BD showed a higher incongruence between their propositions and their emotions[F(1,102)=9.42,P=0.003,η2 p=0.08]and showed strong correlations between the parameters of the Believing Questionnaire and their psychiatric symptoms(r=0.51

关键词： COVID-19 Bipolar disorder Cognition Emotions Judgement Evaluation study