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Holistic Disaster Risk Evaluation for the Urban Risk Management Plan of Manizales,Colombia

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International Journal of Disaster Risk Science 2017年第3期8卷 258-269页

作者： martha Liliana Carreno Omar-Darío Cardona Alex H.Barbat Dora Catalina Suarez mar.a del Pilar Perez Lizardo Narvaez Centre Internacional de Metodes Numerics en Enginyeria Universitat Politècnica de Catalunya Instituto de Estudios Ambientales (IDEA) Universidad Nacional de Colombia Sede Manizales INGENIAR Ltda

Disaster risk depends on both the physical vulnerability and a wide range of social, economic, and environmental aspects of a society. For a better risk understanding, a holistic or integrated perspective was considered when risk was assessed for the city of Manizales, Colombia. This assessment accounts not only for the expected physical damage and loss, but also for the socioeconomic vulnerability factors that favor secondorder effects in a disaster. This comprehensive approach allows the identification of different aspects related to physical vulnerability, social fragility, and lack of resilience that can be improved, thus enhancing integrated disaster risk management actions. The outcomes of this comprehensive assessment are currently being used as input to update the disaster risk management plan of Manizales.

关键词： Holistic risk assessment Manizales (Colombia) Probabilistic risk assessment Risk management plan Urban disaster risk index Urban resilience

Asterohyptis stellulata: Phytochemistry and wound healing activity

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Food Bioscience 2022年第6期50卷 2067-2076页

作者： Nallely Álvarez-Santos Edgar Antonio Estrella-Parra José del Carmen Benítez-Flores Rocío Serrano-Parrales Tomás Ernesto Villamar-Duque martha Angelica Santiago-Santiago mar.a del Rosario González-Valle José Guillermo Avila-Acevedo Ana mar.a García-Bores Phytochemistry Laboratory UBIPROSuperior Studies Faculty (FES)-IztacalaNational Autonomous University of Mexico (UNAM)Tlalnepantla de BazMexico State54090Mexico Postgraduate Biological Sciences Postgraduate Studies UnitNational Autonomous University of Mexico (UNAM)CoyoacanMexico City04510Mexico Histology Laboratory 1 UMFSuperior Studies Faculty (FES)-IztacalaNational Autonomous University of Mexico (UNAM)Tlalnepantla de BazMexico State54090Mexico Natural Products Bioactivity Laboratory UBIPROSuperior Studies Faculty (FES)-IztacalaNational Autonomous University of Mexico (UNAM)Tlalnepantla de BazMexico State54090Mexico Bioterium Superior Studies Faculty (FES)-IztacalaNational Autonomous University of Mexico (UNAM)Tlalnepantla de BazMexico State54090Mexico Plant Physiology Laboratory UBIPROFES-IztacalaUNAMTlalnepantla de BazMexico State54090Mexico

Wound healing is a fast and efficient process. However, several factors can inhibit healing, causing scars and chronic wounds. This affects patients in their physical integrity, economic and emotional stability. Many plants that are used in wound healing treatment have antioxidant/anti-inflammatory activity through ROS regulation and antibacterial activity. Asterohyptis stellulata is used for wound treatment. Nonetheless, this activity has not been evaluated and its secondary metabolites are unknown. Therefore, the objective of this study was to analyze its phytochemical composition and evaluate the healing activity of A. stellulata. For the identification of secondary metabolites, the following were carried out: phytochemical screening, quantification of total phenols, and HPLC/MS analysis. The antibacterial and antioxidant activities were also determined. Next, to evaluate the healing activity of topical application of A. stellulata, the extract was mixed with the Beeler base to form an emulsion and an irritability test was performed. The emulsion was evaluated on incisional wounds of CD1 et/et mice, with tests of tensile strength, total re-epithelialization time, wound closure speed, and histological analysis. The phytochemical analysis showed that A. stellulata has phenolic compounds, two quercetin derivatives and a glycoside rosmarinic acid as main compounds. The extract exhibited medium antibacterial and antioxidant activities. A. stellulata emulsion was non-irritating, promoted closure speed of wound (1.479 ± 0.043 mm/day), increased tensile strength (980 ± 89.44 g), and histological analysis showed it promoted mice skin regeneration, compared to the controls (Recoveron® and Beeler base). This study confirms the traditional use of the A. stellulata.

关键词： Asterohyptis stellulata Phytochemistry Skin regeneration Wound healing

Lymphomatous involvement of gastrointestinal tract: Evaluation by positron emission tomography with ^(18)F-fluorodeoxyglucose

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World Journal of Gastroenterology 2005年第46期11卷 7284-7289页

作者： Sith Phongkitkarun Vithya Varavithya Toshiki Kazama Silvana C Faria martha V mar Donald A Podoloff Homer A Macapinlac Departments of Diagnostic Radiology and Nuclear MedicineBox 057 The University of Texas MDAnderson Cancer Center1515 Holcombe Blvd.HoustonTXUnited States

AIM： To demonstrate the ^18F-fluorodeoxyglucose positron emission tomography （18F-FDG PET） findings in patients with non-Hodgkin＇s lymphoma （NHL） involving the gastrointestinal （GI） tract and the clinical utility of modality despite of the known normal uptake of FDG in the GI tract. METHODS： Thirty-three patients with biopsy-proven gastrointestinal NHL who had undergone FDG-PET scan were induded. All the patients were injected with 10-15 mCJ FDG and scanned approximately 60 min later with a CTI/ Siemens HR （＋） PET scanner. PET scans were reviewed and the maximum standard uptake value （SUVmax） of the lesions was measured before and after the treatment, if data were available and compared with histologic diagnoses. RESULTS： Twenty-five patients had a high-grade lymphoma and eight had a low-grade lymphoma. The stomach was the most common site of the involvement （20 patients）. In high-grade lymphoma, PET showed focal nodular or diffuse hypermetabolic activity. The average SUVmax＋SD was 11.58±5.83. After the therapy, the patients whose biopsies showed no evidence of lymphoma had a lower uptake without focal lesions. The SUVmax＋SD decreased from 11.58±5.83 to 2.21± 0.78. in patients whose post-treatment biopsies showed lymphoma, the SUVmax＋SD was 9.42±6.27. Low-grade follicular lymphomas of the colon and stomach showed diffuse hypermetabolic activity in the bowel wall （SUVmax= 8.2 and 10.3, respectively）. The SUVmax was 2.02-3.8 （mean 3.02） in the stomach lesions of patients with MALT lymphoma. CONCLUSION： ^18F-FDG PET contributes to the diagnosis of high-grade gastrointestinal non-Hodgldn＇s lymphoma, even when there is the normal background FDG activity. Furthermore, the SUV plays a role in evaluating treatment response. Low-grade NHL demonstrates FDG uptake but at a lesser intensity than seen in high-grade NHL.

关键词： Positron emission tomography Non-Hodgkin's lymphoma Gastrointestinal neoplasm

A Novel Method to Improve Quality of Drinking Water, Based on the Eye’s Biology

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Journal of Water Resource and Protection 2022年第4期14卷 318-333页

作者： Arturo Solís Herrera mar.a del Carmen Arias Esparza martha Patricia Solís Arias Human Photosynthesis^TM Research Centre Aguascalientes México

Water represents a critical nutrient, the absence of which will be lethal within days. Water’s importance for the prevention of nutrition-related noncommunicable diseases has received more attention recently. There are major gaps in knowledge related to the measurement of total fluid intake and hydration status at the population level. It is poorly understood the effects of chronic mild dehydration and fluid consumption on specific health outcomes including obesity. Urolithiasis is the only disorder that has been consistently associated with chronic low daily water intake. Water is an essential nutrient required for life, but until now, it was considered mainly as a universal solvent, which served to prepare the broth of life inside the cells, but the function of water now takes unusual importance with our discovery of the unsuspected ability of the human body to transform the power of light into chemical energy by dissociating the molecule from water, as it happens in plants. The process that we replicated in the laboratory for the first time in 2007, represents a light at the end of the tunnel, in the growing and serious problem of contamination of the mysterious and vital liquid that we call water.

关键词： Drinking Water Hydrogen Oxygen Dissolved Oxygen Pollution Human Eye

Study Nanostructure of a Biomaterial with Medicine Therapeutic Activity

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Microscopy Research 2016年第2期4卷 32-38页

作者： marilú Chávez-Castillo martha Lilia Domínguez-Patiño Rosa mar.a Melgoza-Alemán Centro de Investigación en Ingeniería y Ciencias Aplicadas Universidad Autónoma del Estado de Morelos Cuernavaca México Facultad de Ciencias Químicas e Ingeniería Universidad Autónoma del Estado de Morelos Cuernavaca México

In Mexico, the medicinal plants have been for used since ancient times and still continue to use by rural populations to treat conditions such as infectious diseases (skin, gastrointestinal or respiratory), metabolics, inflammatory problems, among others. This work includes a proposal that initiates the study and development of new biomaterials or vehicles with therapeutic application. The nanomolecular interaction of the organic extract of a plant (EOV) Distictis buccinatoria (dc) with different materials inert supports of inorganic type (bentonite, gel) determining their and combined anti-inflammatory activity is studied individually [1] [2]. The importance of the characterization of biomaterials by scanning electron microscopy (SEM) is ability to analyze the structure on the surface of materials (organic, inorganic and biological) in the micro and nanometrics levels in order to correlate it with the sample surface properties such as roughness, interfacial phenomena, etc. With this technique we can also perform the chemical analysis at different levels (micro and nano) for information on the nature and composition of the materials [3] [4]. The biomaterial shows that higher anti-inflammatory activity is to be generated through the combination of EOV-gel, the nanostructure interaction SEM shows integrated particles agglome-rated form and porous due to the presence of EOV and some flat areas indicated the gel preponderance situation generated by the low interaction between materials of organic type and polar type (gel).

关键词： Biomaterials Nanomolecular Anti-Inflamatory Vehicles

Comparison of Apigenin,Quercetin and Kaempferol Accumulation and Total Flavonoid Content in Leaves,Embryogenic Cultures and Cell Suspension Cultures of Parsley(Petroselinum crispum)

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Phyton-International Journal of Experimental Botany 2023年第10期92卷 2807-2823页

作者： Laura Isabel Arias-Rodríguez martha Alicia Rodríguez-Mendiola Carlos Arias-Castro Federico Antonio Gutiérrez Miceli Diana Reséndez Pérez mar.a Celina Luján Hidalgo Juan JoséVillalobos Maldonado Norma Alejandra Mancilla mar.alli Analytical Laboratory National Technological Institute of MexicoTuxtla Gutierrez CampusTuxtla GutierrezMexico Plant Biotechnology Laboratory Instrumental Analysis LaboratoryPlant Biochemistry LaboratoryNational Technological Institute of MexicoTlajomulco de ZunigaMexico Department of Cellular Biology and Genetics Faculty of Biological SciencesAutonomous University of Nuevo LeonSan Nicolas delos GarzaMexico

In recent years,there has been a growing interest in exploring alternative treatments for bone *** tissue engineering has turned its attention to plant extracts containing osteogenic flavonoids as potential promoters of bone *** our study,we specifically investigated the extract of Petroselinum crispum,a plant known for its abundance of osteogenic flavonoids such as apigenin,quercetin,and *** objective was to compare the total flavonoid content(TFC)and their accumulation in different *** obtained hydrolyzed aqueous extracts from the leaves of parsley plants(grown for 12 weeks in the field),weekly embryogenic cultures,and suspension cell *** TFC,measured in mg quercetin equivalent per gram of dry weight(QE mg/g dw),was found to be 53.81±0.97 for 52 g dw of leaves(1 kg plant fw),31.10±1.52 for 420 g dw of embryogenic cultures,and 11.80±0.76 for 210 g dw of cell ***,only the leaves and embryogenic cultures showed significant accumulation of osteogenic flavonoids,with apigenin levels of 1.8±0.3 and 0.32±0.02 mg/g dw,and kaempferol levels of 1.0±0.18 and 0.2±0.01 mg/g dw,*** findings indicate that embryogenic cultures have the potential to produce up to 40%more apigenin in 12 weeks compared to 1 kg of parsley plant,thanks to their superior biomass reproductive *** results present a promising biotechnological approach for generating extracts enriched with bioactive compounds,which can be further utilized in in vitro osteogenic testing.

关键词： Parsley(Petroselinum crispum)cultures osteogenic flavonoids bone regeneration aqueous extracts

Simulaccion Processes of a Mathematical Model to Determine the Growth of Tomato under Plastic Cover

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Agricultural Sciences 2015年第12期6卷 1532-1537页

作者： Luz Elva marín Vaca martha Lilia Domínguez Patino Nadia Lara Ruiz Miguel Aguilar Cortes Centro de Investigacion en Ingenieria y Ciencias Aplicadas Universidad Autonoma del Estado de MorelosCuernavacaMexico Facultad de Ciencias Quimicas e Ingenieria Universidad Autonoma del Estado de MorelosCuernavacaMexico

The tomato is one of the horticultural crops of the greatest economic value;for this reason, flexibility of management is usable. The population density in a crop of vegetables is determined by the distance between the plants and so it is necessary to choose the number of plants per square meter since the saturation of plants will lead to competition between sunlight, nutrients and weed. The objective of this work is to make the appropriate investigation for the use of the model proposed in order to describe the growth of tomato in greenhouse to high density of two plants per container to two bunches per plant, resulting in eight plants per square meter to grow, by means of a simulator of growth by computer. Of this work, it is concluded that it is possible to use the model to describe the growth of plants, and in the near future it will be possible to develop a simulator by computer of the growth of these crops in order to improve their quality and increase their production.

关键词： Simulation Plastic Cover Tomato

Anatomical characterization of central, apical and minimal corneal thickness

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International Journal of Ophthalmology(English edition) 2014年第4期7卷 668-672页

作者： Federico Saenz-Frances martha Cecilia Bermúdez-Vallecilla Lara Borrego-Sanz Luis Jaez J osé mar.a martinez-de-la-Casa Laura Morales-Fernandez Enrique Santos-Bueso Julián Garcia-Sanchez Julián Garcia-Feijoo Department of Ophthalmology Hospital Clínico San CarlosUniversidad Complutense de Madrid Instituto de Tecnologìa del Conocimiento Universidad Complutense de Madrid

·AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness(pupil center) in relation to the corneal apex.·METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex(AT),minimum corneal thickness(MT) and corneal thickness at the pupil center(PT) were determined using the pentacam. Distances from the corneal apex to MT(MD)and PT(PD) were calculated and their quadrant position(taking the corneal apex as the reference) determined:point of minimum thickness(MC) and point of central thickness(PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume(determined using the Pentacam)and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.·RESULTS: MT was located at a mean distance of 0.909 mm from the apex(79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume(B =-0.024; 95% CI:-0.043 to-0.004). No significant relations were identified in the linear regression model for PD or the multinomial logisticregressions for MC and PC.·CONCLUSION: MT was typically located at the inferiortemporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.

关键词： cornealthickness anatomy glaucoma

Nutritional Status, Food Consumption at Home, and Preference-Selection in the School

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Food and Nutrition Sciences 2012年第3期3卷 281-285页

作者： mar.a del Refugio López-Gamino martha Elba Alarcón-Armendáriz Xochitl Karina Torres-Beltrán Educación para la Salud FES IztacalaUniversidad Nacional Autónoma de MéxicoMéxico CityMéxico.

To assess the relationship between food consumption at home, nutritional status, gender preference and the preference-selection of natural products (fruits and vegetables) and industrialized (candies and chips) in a situation of free access for a population of Mexican schoolchildren. 115 children participated in the test, 59 boys and 56 girls from second, fourth and sixth grade of elementary school. We have taken measures of weight, size and the 24-hour consumption record during over five days, at which time also we evaluated the preference and selection of a group of ten products (naturals and industrialized). According to the results 60% of children had normal weight, 23.47% overweight, 14.8% risk of overweight an 1.73% underweight. There were no significant differences with X2 test between nutritional status and gender. Multivariate analysis was applied between gender, consumption by food groups and nutritional status, the interaction was significant in all cases. The Pearson correlation between preference and food choice in the situation of open access is high in the school students at risk of overweight. The preferred and selected products for consumption are those with the highest content of saturated fat, sugars and salt, the less preferred and selected products were fruits and vegetables. We could conclude that the population is at risk for their low consumption of fruits and vegetables;situation that is reflection of the home consumption this document.

关键词： Food Preferences Diet Schoolchild Nutritional Status