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Refractive outcomes after V4c Toric collamer lens implantation over 1y of follow-up

International Journal of Ophthalmology(English edition) 2024年第7期17卷 1322-1330页

作者： Humberto carre.as-díaz Josefina Reñones de.Abajo mar.a de. rosario carre.as-díaz Amalia Lorente-Velázquez Vithas Eurocanarias Las Palmas de Gran Canaria 35004Spain University Hospital of Girona doctor Josep Trueta Gerona 17007Spain de.artament of Optometry and Vision Faculty of Optics and OptometryComplutense University of MadridMadrid 28040Spain

AIM:To evaluate refractive outcomes and corneal astigmatism changes after Toric implantable collamer lens with a central port(V4c T-ICL)implantation over 1y of ***:A retrospective study was performed including 50 eyes of 50 patients that unde.went V4c T-ICL ***(UdVA)and corrected(CdVA)distance visual acuities,refraction,refractive and corneal astigmatism changes and corneal coupling correction were evaluated preoperatively,1 and 12mo *** analysis was used for astigmatism *** of adjustment(CAdj)was calculated for corneal coupling ***:The mean UdVA achieved was 0.03 logmar.at 1mo and remained unchanged throughout the whole follow-up(P=0.193).At the last visit,84%of the eyes achieved a CdVA of 0.00 logmar or *** spherical equivalent refraction(SEQ),96%of eyes were ranges of±1.00 d and 84%of them within±0.50 ***,94%of eyes had a remaining refractive cylinde. within±1.00 d and 78%of them within±0.50 ***,SEQ and refractive cylinde.,remain stable over the postoperative follow-up(P=1.000 and P=0.660,respectively).In terms of surgically induced astigmatism(SIA),no statistically significant differences were found over the follow-up(P=0.102)and unde. correction was found with a correction inde. lower than the unit at each visit.A keratometric astigmatism induced of 0.59±0.53(vector mean:0.26×73º)d was reached at the last *** significant changes in terms of corneal astigmatism orientation were reported over post-surgery visits(P=0.129 and P=0.097 at 1 and 12mo respectively).No clinical significance was found for CAdj on with-the-rule *** postoperative complications resulting from the surgery were ***:Refractive outcomes suggest that the V4c T-ICL implantation for correction of myopic astigmatism was satisfactory in terms of effectiveness,safety,and stability during 1y of *** astigmatism induced by the incision around 0.5 d is achieved

关键词： V4c Toric collamer lens corneal astigmatism surgically induced astigmatism corneal coupling

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University Corporate Governance in the Literature From 2019 to 2024

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Journalism and Mass Communication 2024年第3期14卷 179-188页

作者： mar.a de. rosario Molina González mar.a Teresa Gaxiola Sánchez mar.a de.Jesús Camargo Pacheco marco Antonio Velde.rain Rodríguez Rafael Campoy Mendoza Cruz García Lirios Universidad de.Sonora NavojoaMexico

Anti-pande.ic policies impacted the governance of Higher Education Institutions(HEIs)through confinement and distancing *** an impact was observed in the ide.tity,reputation,and image of the HEI in the face of the health *** objective of this work was to establish an empirical contrast between the theoretical structure consulted regarding the evaluations of summaries published from 2019 to 2024 by judges.A documentary,cross-sectional,and retrospective study was carried out with a sample of sources inde.ed in international *** results de.onstrate that image and age regulate the impact of ide.tity and income on *** relation to the state of the art,it is recommende. to extend the study to sociocultural,de.ographic,economic,and educational variables in orde. to anticipate the transition from university governance to corporate governance.

关键词： COVId governance mode. node. neural networks

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola Mavillard Javier Perez-Florido Francisco M.Ortuño Amador Valladares Miren L.Álvarez-Villegas Gema Roldán rosario Carmona Manuel Soriano Santiago Susarte Pilar Fuentes daniel López-López Ana mar.a Nuñez-Negrillo Alejandra Carvajal Yolanda Morgado daniel Arteaga Rosa Ufano Pablo Mir Juan F.Gamella Joaquín dopazo Carmen Paradas Macarena Cabrera-Serrano Instituto de.Biomedicina de.Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedade. Neurode.enerativas(CIBERNEd) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de.Medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de.medicina computacional de.sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de.Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedade. raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain de.artamento de.Ingeniería de.Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de.Urgencias de.Atención Primar.a Distrito SevillaSevillaSpain Centro de.Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain de.artamento de.Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain de.artamento de.Neurología Hospital Virgen de las NievesGranadaSpain de.artamento de.Neurología Hospital Virgen de ValmeSevillaSpain Centro de.Salud Utrera Sur SevillaSpain Centro de.Salud Polígono Sur SevillaSpain Unidad de.Trastornos de. Movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain de.artamento de.Medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain de.artamento de.Antropología Social Universidad de GranadaSpain Unidad Enfermedade. Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the wide.pread adoption of cost-effective massive parallel *** ide.tify new disease variants,especially in monogenic disorde.s,a frequen... 详细信息

关键词： Server filtering massive

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Glutaminolysis-ammonia-urea Cycle Axis,Non-alcoholic Fatty Liver disease Progression and de.elopment of Novel Therapies

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Journal of Clinical and Translational Hepatology 2022年第2期10卷 356-362页

作者： Ángela Rojas mar.a rosario García-Lozano Antonio Gil-Gómez Manuel Romero-Gómez Javier Ampuero de.artment of Unit of digestive diseases Virgen del Rocío University HospitalSevilleSpain SeLiver group at the Insti-tute of Biomedicine of Seville(IBIS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain Center for the Study of Liver and Gastrointestinal diseases(CIBERehd) Carlos III National Institute of HealthMadridSpain de.partment of Organic and Medicinal Chemistry Faculty of PharmacyUniversity of SevilleE-41071SevilleSpain

The prevalence of non-alcoholic fatty liver disease(NAFLd)is increasing worldwide.reflecting the current epide.ics of obesity,insulin resistance,type 2 diabetes mellitus,and metabolic *** is characterized by the accumulation of fat in the liver,and is known to be a cause of *** many pathways have been proposed,the cause of NAFLd-linked fibrosis progression is still unclear,which posed challenges for the de.elopment of new therapies to prevent NASH-related cirrhosis and hepatocellular *** is associated with activation of hepatic stellate cells(HSC)and accumulation of excess extracellular matrix proteins,and inhibiting the activation of HSCs would be expected to slow the progression of *** molecular signals and pathways such as oxidative stress and glutaminolysis have been reported to promote HSC *** mechanisms are plausible antifibrotic targets in NASH,as the activation of HSCs the proliferation of myofibroblasts de.end on those *** review summarizes the role of the glutaminolysis-ammonia-urea cycle axis in the context of NAFLd progression,and shows how the axis could be a novel therapeutic target.

关键词： Non-alcoholic fatty liver disease Cirrhosis Fibrosis Glutaminoly-sis Ammonia Urea

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ACE Score Ide.tifies HBeAg-negative Inactive Carriers at a Single-point Evaluation,Regardless of HBV Genotype

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1068-1076页

作者： Luisa Roade.mar Riveiro-Barciela Adriana Palom Francisco Rodríguez-Frías mar.a Bes Ariadna Rando mar.a Teresa Salcedo rosario Casillas Elena Vargas-Accarino david Tabernero Silvia Sauleda Rafael Esteban mar.a Buti Liver Unit Internal Medicine DepartmentHospital Universitari Vall d’HebronVall d’Hebron Barcelona Hospital CampusBarcelonaSpain Universitat Autònoma de.Barcelona(UAB) Department of MedicineBarcelonaSpain Universitat Au-tònoma de.Barcelona(UAB) Department of Biochemistry and Molecular BiologyBarcelonaSpain Centro de.Investigación Biomédica en Red de.Enfermedade. Hepáticas y digestivas(CIBERehd) Instituto de Salud Carlos IIIMadridSpain Liver Pathology Lab Biochemistry and Microbiology Departments(Clinical Laboratories)Hospital Universitari Vall d’HebronVall d’Hebron Barcelona Hospital CampusBarcelonaSpain Vall d’Hebron Institut de.Recerca(VHIR) Liver Diseases GroupBarcelonaSpain Transfusion Safety Laboratory Banc de Sang i TeixitsServei Catalàde la SalutBarcelonaSpain de.partment of Pathology Hospital Universitari Vall d’HebronUniversitat Autònoma de BarcelonaBarcelonaSpain

Background and Aims:Hepatitis B virus(HBV)biomark-ers have been used for a better categorization of patients,even though the lack of simple algorithms and the impact of genotypes limit their *** aim was to assess the usefulness of noninvasive markers for the ide.tification of HBV inactive carriers(ICs)in a single-point evaluation and to de.ign a predictive mode. for their ***-ods:This retrospective-prospective study include. 343 consecutive HBeAg-negative ***,analytical,and virological data were collected,and a liver biopsy was performed if *** were classified at the end of follow-up as ICs,chronic hepatitis B and gray zone.A pre-dictive mode. was constructed,and validated by 1000-boot-strap ***:After 39 months of follow-up,298 subjects were ICs,36 were chronic hepatitis B CHB,and nine were gray ***-nine(25.9%)individuals re-quired a liver *** HBV dNA hazard ratio(HR)6.0,pd antigen(HBcrAg)(HR 6.5,pd elastography(HR 4.6,pde.pende.tly associated with the IC *** ACE score(HBV dNA,HBcrAg,elastography),obtained by bootstrapping,yielde. an area unde. the receiver operating characteris-tics(AUROC)of 0.925(95%CI:0.880-0.970,pde.tification of *** AUROC for genotype d was 0.95,0.96 for A,0.90 for E,and 0.88 for H/*** ACE score ofd a positive predictive value of 99.5%,and a score≤12 points had a diagnostic accuracy of 93.8%.Conclusions:Low baseline HBV dNA,HBcrAg,and liver stiffness were in-de.ende.tly associated with the IC phase.A score including those variables ide.tified ICs at a single-point evaluation,and might be applied to implement less intensive follow-up strategies.

关键词： Hepatitis B virus Inactive carrier Liver stiffness HBV dNA Quan-titative HBsAg Core-related antigen.

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Mobility Habitus in the Literature From 2020 to 2024

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Journalism and Mass Communication 2024年第2期14卷 53-62页

作者： mar.a de. rosario Molina González Cruz García Lirios Julio E Crespo Isabel Cristina Rincón Rodríguez Jorge Enrique Chaparro Medina Francisco Rubén Sandoval Vázquez Enrique martínez Muñoz JoséAlfonso Aguilar Fuentes Alfredo Barrera Escobar Universidad de.Sonora NavojoaMéxico Universidad de.la Salud Ciudad de MexicoMéxico Universidad de.Los Lagos OsornoChile Universidad de.Santande. Ude. BucaramangaColombia Universidad de.Investigación y de.arrollo UdI BucaramangaColombia Universidad Autónoma de. Estado de.Morelos CuernavacaMéxico Universidad Autónoma de. Estado de.Hidalgo PachucaMéxico Universidad Autónoma de. Estado de.México HuehuetocaMéxico Universidad Fide. Velazquez EdomexMéxico

The objective of the present work is mode.ing the mobility habitus in the public transport system with low Co2 emission mechanics in the center of *** this sense,a documentary work was carried out with a review of sources inde.ed to national repositories,using the de.phi technique for the content analysis and the specification of the mode..A study was conducted with a selection of 100 stude.ts to establish the reliability,linearity,sphericity,ade.uacy,and validity of an instrument from which a relationship of de.ende.ce between income and mobility habitus was *** limits of the search,selection,and processing of information are recognized,and it is recommende. to extend the research to international repositories,as well as to employ a more sophisticated technique.

关键词： spatiality habitus capacities mode. complexity

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Soil organic carbon stocks in native forest of Argentina:a useful surrogate for mitigation and conservation planning unde. climate variability

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Ecological Processes 2024年第1期13卷 3-24页

作者： Pablo L.Peri Juan Gaitán Matías Mastrangelo marcelo Nosetto Pablo E.Villagra Ezequiel Balducci martín Pinazo Roxana P.Eclesia Alejandra Von Wallis Sebastián Villarino Francisco Alaggia marina González Polo Silvina Manrique Pablo A.Meglioli Julián Rodríguez-Souilla martín Mónaco Jimena E.Chaves Ariel Medina Ignacio Gasparri Eugenio Alvarez Arnesi mar.a Paula Barral Axel von Müller Norberto M.Pahr Josefina Uribe Echevarria Pedro Fernánde. marina Morsucci dardo López Juan Manuel Cellini Leandro Alvarez Ignacio Barberis Hernán Colomb Ludmila La Manna Sebastián Barbaro Cecilia Blundo Ximena Sirimarco Laura Cavallero Gualberto Zalazar Guillermo martínez Pastur Instituto Nacional de.Tecnología Agropecuaria (INTA) Universidad Nacional de.la Patagonia Austral (UNPA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Universidad Nacional de.Luján Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Grupo de.Estudio de.Agroecosistemas y Paisajes Rurales (GEAP) Universidad Nacional de Mar del Plata Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET ) CCT San Luis Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto Argentino de.Nivología Glaciología y Ciencias Ambientales (IANIGLA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Universidad Nacional de Cuyo Instituto de.Investigaciones en Biodiversidad y Medioambiente (INIBIOMA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Instituto de.Investigaciones en Energía No Convencional CCT Salta-JujuyConsejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Laboratorio de.Recursos Agroforestales Centro Austral de Investigaciones Científicas (CADIC) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) dirección Nacional de.Bosques Ministerio de Ambiente y Desarrollo Sostenible de la Nación Instituto de.Ecología Regional Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )Universidad Nacional de Tucumán Universidad Nacional de.rosario Instituto de Investigaciones en Ciencias Agrarias de Rosario Centro Científico Tecnológico CONICET Grupo de.Estudio de.Agroecosistemas y Paisajes Rurales (GEAP) Universidad Nacional de Mar del Plata Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Laboratorio de.Investigaciones en Made.as (LIMAd) Universidad Nacional de La Plata (UNLP) Administración de.Parques Nacionales (APN) Parque Nacional Los Alerces Centro de.Estudios Ambientales Integrados (CEAI) Universidad Nacional de la Patagonia San Juan Bosco (UNPASJB) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET )

Background The nationally de.ermined contribution（NdC） presented by Argentina within the framework of the Paris Agreement is aligned with the de.isions made.in the context of the United Nations Framework Conven-tion on Climate Change（UNFCCC） on the reduction of emissions de.ived from de.orestation and forest de.radation, as well as forest carbon conservation（REdd+）. In addition, climate change constitutes one of the greatest threats to forest biodiversity and ecosystem services. However, the soil organic carbon（SOC） stocks of native forests have not been incorporated into the Forest Reference Emission Levels calculations and for conservation planning unde. cli-mate variability due to a lack of information. The objectives of this study were:（i） to mode. SOC stocks to 30 cm of native forests at a national scale using climatic, topographic and vegetation as predictor variables, and（ii） to relate SOC stocks with spatial–temporal remotely sensed indices to de.ermine biodiversity conservation concerns due to threats from high inter-annual climate *** We used 1040 forest soil samples（0–30 cm） to generate spatially explicit estimates of SOC native forests in Argentina at a spatial resolution of approximately 200 m. We selected 52 potential predictive environmental covari-ates, which represent key factors for the spatial distribution of SOC. All covariate maps were uploade. to the Google Earth Engine cloud-based computing platform for subsequent mode.ling. To de.ermine the biodiversity threats from high inter-annual climate variability, we employed the spatial–temporal satellite-de.ived indices based on Enhanced Vegetation Inde.（EVI） and land surface temperature（LST） images from Landsat *** SOC mode.（0–30 cm de.th） prediction accounted for 69% of the variation of this soil property across the whole native forest coverage in Argentina. Total mean SOC stock reached 2.81 Pg C（2.71–2.84 Pg C with a probability of 90%） for a total area of 460,790 km2,

关键词： Soil organic carbon Biodiversity Native forest Climate change mitigation Mode.ling Resilience

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Enhancement of a foaming formulation with a zwitterionic surfactant for gas mobility control in harsh reservoir conditions

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Petroleum Science 2021年第5期18卷 1409-1426页

作者： Miguel Angel Roncoroni Pedro Romero Jesús Montes Guido Bascialla rosario Rodríguez Ramón Rodríguez Pons-Esparver Luis Felipe Mazadiego mar.a Flor García-Mayoral Universidad Politécnica de.Madrid MadridSpain CEPSA Research Center MadridSpain CEPSA E&P MadridSpain

This work presents the de.ign of a robust foam formulation that tolerates harsh reservoir conditions(high salinity,high divalent ion concentration,high temperature,light oil,and hydrocarbon injection gas)in a sandstone *** this,we selected anionic Alpha Olefin Sulfonate(AOS)surfactants and studied their synergistic effects in mixtures with zwitterionic betaines to enhance foam *** laboratory workflow used to de.ine the best formulation followed a de.risking approach in three consecutive ***,(phase 1)the main surfactant(AOS)was selected among a series of commercial candidates in static ***,(phase 2)the betaine booster to be combined with the previously selected AOS was chosen and their ratio optimized in static ***,(phase 3)the surfactant/booster ratio was optimized unde. dynamic conditions in a porous medium in the absence and the presence of *** a result of this study,a mixture of an AOS C14-C16 and cocamidopropyl hydroxysultaine(CAPHS)was selected as the one having the best *** de.igned formulation was proven to be robust in a wide.range of *** generated a strong and stable foam at reservoir conditions,overcoming variations in salinity and foam quality,and tolerated the presence of oil.

关键词： Gas mobility control Foam enhanced oil recovery(EOR) Foam stability High temperature high salinity reservoir Surfactant formulation

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Type XIX collagen: a promising biomarker from the basement membranes

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Neural Regeneration Research 2020年第6期15卷 988-995页

作者： Ana C.Calvo Laura Moreno Leticia Moreno Janne M.Toivonen Raquel Manzano Nora Molina Miriam de.la Torre Tresa López Francisco J.Miana-Mena mar.a J.Munoz Pilar Zaragoza Pilar Larrodé Alberto García-Redondo rosario Osta Laboratory of Genetics and Biochemistry(LAGENBIO) University of ZaragozaFaculty of Veterinary SciencesInstituto de Investigación Sanitaria de Aragón(IIS)IA2CIBERNEDZaragozaSpain Hospital Clínico Universitario Lozano Blesa ZaragozaSpain Neurology de.artment ALS UnitCIBERER U-723Health Research InstituteMadridSpain

Among collagen members in the collagen superfamily,type XIX collagen has raised increasing interest in relation to its structural and biological *** XIX collagen is a Fibril-Associated Collagen with Interrupted Triple helices member,one main subclass of collagens in this *** collagen contains a triple helix composed of three polypeptide.segments aligned in parallel and it is associated with the basement membrane zone in different *** molecular structure of type XIX collagen consists of five collagenous domains,COL1 to COL5,interrupted by six non-collagenous domains,NCI to *** most relevant domain by which this collagen exerts its biological roles is NCI domain that can be cleavage enzymatically to release matricryptins,exerting anti-tumor and anti-angiogenic effect in murine and human mode.s of *** physiological conditions,type XIX collagen expression de.reases after birth in different tissues although it is necessary to keep its basal levels,mainly in skeletal muscle and hippocampal and telencephalic interneurons in ***,in amyotrophic lateral sclerosis,altered transcript expression levels show a novel biological effect of this collagen beyond its structural role in basement membranes and its anti-tumor and anti-angiogenic *** XIX collagen can exert a compensatory effect to ameliorate the disease progression unde. neurode.enerative conditions specific to amyotrophic lateral sclerosis in transgenic SOd1 G93 A mice and amyotrophic lateral sclerosis *** novel biological role highlights its nature as prognostic biomarker of disease progression in and as promising therapeutic target,paving the way to a more precise prognosis of amyotrophic lateral sclerosis.

关键词： anti-tumor and anti-angiogenic properties C1 domain COL19A1 gene and protein levels compensatory effect FACIT collagens hippocampal interneurons matricryptins multiplexins NC1 domain regenerative response skeletal muscle type XIX collagen

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Assessment of Lipid Quality and Composition of Commercial Infant Milk Formulas in Mexico: Emphasis on Trans Fatty Acid Isomers

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Food and Nutrition Sciences 2016年第4期7卷 273-283页

作者： Ayala-Moreno mar.a de. rosario Fernánde.-Callejas José mar.a Salvador Maldonado-Hernánde. Jorge Food and Health Research Group School of Chemistry Universidad La Salle Mexico City Mexico Mass Spectrometry Laboratory Research Unit in Medical Nutrition Pediatric Hospital National Medical Center “Siglo 21” Mexican Institute of Social Security Mexico City Mexico

Objective: To assess the lipid quality focusing on trans fatty acids (TFA) content of standardized milk formulas marketed in Mexico for infants aged from 0 to 36 months. Material and Methods: A total of 27 infant formulas from eight different leading brands were analyzed. Nine of them belonged to stage 1 (age 12 months). Acquired products were treated by duplicate for extraction of total lipid content with the modified Folch method before their expiration date. Fatty acids were esterified in an alkaline medium followed by an acid-catalyzed esterification. Analysis was performed on a gas chromatograph (5890 Series II;Hewlett-Packard, USA) with a flame ionization de.ector. Results: Thirty-four fatty acids (C8 to C22) were ide.tified. Most products complied with ESPHAGAN compositional requirements. Only one product exceede. the suggested limit (>3%) for TFA. Long chain polyunsaturated fatty acids (LC-PUFAs) content was consistently meager (≈78%), with low amounts of arachidonic (Conclusion: Most milk formulas complied with ESPHAGAN global recommendations. The content of TFA and LC-PUFAs was scarce in the majority of samples.

关键词： Infant Formulas Milk Lipid Quality TransFatty Acids

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