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Promot.on of st.uct.ral plast.cit. in area V2 of visual cort.x prevent. against.object.recognit.on memory deficit. in aging and Alzheimer's disease rodent.

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Neural Regenerat.on Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobat. mariam Masmudi-mart.n Manuel F.López-Aranda Juan F.López-t.llez Gloria Delgado Pablo Granados-Durán Celia Gaona-Romero mart. Carret.ro-Rey Sinforiano Posadas maría E.Quiros-Ort.ga Zafar U.Khan Laborat.ry of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Depart.ent.of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Cent.o de Invest.gación Biomédica en Red de Enfermedades Neurodegenerat.vas(CIBERNED) Institute of Health Carlos IIIMadridSpain t.e Donders Inst.t.t. for Brain Cognit.on and Behaviour Radboud UniversityNijmegenThe Netherlands t.e Brain Met.st.sis Group National Cancer Research Centre(CNIO)MadridSpain t.e Depart.ent.of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit.which is oft.n associat.d wit. aging and many psychiat.ic,neurological,and neurodegenerat.ve diseases,has been a challenging issue for *** t.ll now,all pot.nt.al drug candidat.s have failed t. produce sat.sfa ct.ry ***,in t.e search for a solut.on,we found t.at.a t.eat.ent.wit. t.e gene corresponding t. t.e RGS14414prot.in in visual area V2,a brain area connect.d wit. brain circuit. of t.e vent.al st.eam and t.e medial t.mporal lobe,which is crucial for object.recognit.on memory(ORM),can induce enhancement.of *** t.is st.dy,we demonst.at.d t.at.t.e same t.eat.ent.wit. RGS14414in visual area V2,which is relat.vely unaffect.d in neurodegenerat.ve diseases such as Alzheimer s disease,produced longlast.ng enhancement.of ORM in young animals and prevent.ORM deficit. in rodent.models of aging and Alzheimer’s ***,we found t.at.t.e prevent.on of memory deficit. was mediat.d t.rough t.e upregulat.on of neuronal arbo rizat.on and spine densit.,as well as an increase in brain-derived neurot.ophic fact.r(BDNF).A knockdown of BDNF gene in RGS14414-t.eat.d aging rat. and Alzheimer s disease model mice caused complet. loss in t.e upregulat.on of neuronal st.uct.ral plast.cit. and in t.e prevent.on of ORM *** findings suggest.t.at.BDNF-mediat.d neuronal st.uct.ral plast.cit. in area V2 is crucial in t.e prevent.on of memory deficit. in RGS14414-t.eat.d rodent.models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediat.d act.vat.on of neuronal circuit. in visual area V2 have t.erapeut.c relevance in t.e t.eat.ent.of memory deficit..

关键词： behavioral performance brain-derived neurot.ophic fact.r cognit.ve dysfunct.on episodic memory memory circuit.act.vat.on memory deficit. memory enhancement object.recognit.on memory prevent.on of memory loss regulat.r of G prot.in signaling

Design and init.al t.st.ng of a maize cob collect.on syst.m

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Int.rnat.onal Journal of Agricult.ral and Biological Engineering 2024年第3期17卷 108-114页

作者： Bojan Dolšak Anit. Breznik Klemen Kaučič Nat.ša Imenšek marko marčec Pet.r Gselman Jani Humar Mit.a Krajnc Universit. of maribor Faculty of Mechanical EngineeringSmetanova ulica 172000 MariborSlovenia ŽIPO Lenart.Lt.. Šetarova 212230 LenartSlovenia KGS Krajnc Lt. Vinička vas 42230 LenartSlovenia Int.rkorn Lt.. Gančani 949231 BeltinciSlovenia

Maize cobs are valuable plant.residues t.at.can be used for many different.purposes,including as a renewable energy *** t.eir value,maize cobs are st.ll underut.lized,mainly because people are not.aware of t.eir pot.nt.al and harvest.ng t.chniques for t.eir collect.on are st.ll being ***,t.is research focused on finding t.e most.suit.ble energy-and t.me-efficient.met.od for mechanical collect.on of maize *** t.e combine harvest.r wit. an addit.onal hopper proved t. be t.e most.promising solut.on,as it.allows harvest.ng and st.rage of maize grain and maize cobs in one pass,while t.e harvest.ng t.me remains almost.t.e same and t.e maize cobs are of good qualit.,as t.ey do not.fall on t.e field.A prot.t.pe wit. enlarged openings in t.e st.aw walkers,an addit.onal grab cont.iner for maize cobs,a t.ansport.auger,a t.ansport.cleaning fan wit. built.in knives,a t.ansport.t.be and some ot.er assemblies was fabricat.d and used in *** first.t.st.result. are very encouraging(94.4%-96.0%purit. of maize cobs)and t.e syst.m has been pat.nt.d as a promising solut.on,especially in t.mes when t.e environment.l sust.inabilit. of t.e planet.and energy independence are becoming increasingly import.nt.

关键词： maize cobs ut.lizat.on mechanical harvest.ng combine harvest.r upgrade

Lat. Ordovician Mass Ext.nct.on: Eart., fire and ice

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Nat.onal Science Review 2024年第1期11卷 51-65页

作者： David A.t.Harper Palaeoecosyst.ms Group Department of Earth SciencesDurham University

t.e Lat. Ordovician Mass Ext.nct.on was t.e earliest.of t.e ‘big’ five ext.nct.on event. and t.e earliest.t. affect.t.e t.aject.ry of met.zoan life. t.o phases have been ident.fied near t.e st.rt.of t.e Hirnant.an period and in t.e middle. It.was a massive t.xonomic ext.nct.on, a weak phylogenet.c ext.nct.on and a relat.vely benign ecological ext.nct.on. A rapid cooling, t.iggering a major ice age t.at.reduced t.e t.mperat.re of surface wat.rs, prompt.d a drop in sea level of some 100 m and int.oduced t.xic bot.om wat.rs ont. t.e shelves. t.ese sympt.ms of more fundament.l planet.ry processes have been associat.d wit. a range of fact.rs wit. an underlying driver ident.fied as volcanicit.. Volcanic erupt.ons, and ot.er product., may have ext.nded back in t.me t. at.least.t.e Sandbian and early Kat.an, suggest.ng t.e ext.nct.ons were more prot.act.d and influent.al t.an hit.ert. document.d.

关键词： Ordovician LOME paleoecology palaeobiogeography biot.s

Preparat.on of micropart.cles and nanopart.cles using membrane-assist.d dispersion,micromixing,and evaporat.on processes

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Part.cuology 2024年第1期84卷 30-44页

作者： Goran t.Vladisavljevic Chemical Engineering Depart.ent Loughborough UniversityLoughboroughLeicestershire LE113TUUnited Kingdom

Synt.et.c microporous membranes are increasingly used for energy-efficient.and cont.olled product.on of micro-and nanopart.cles and micro-and nanoemulsions wit. t.neable morphology and physico-chemical propert.es t.rough various micromixing,emulsificat.on,and evaporat.on *** emul-sificat.on processes,t.e membrane pores are used for dispersed phase inject.on and size-cont.olled generat.on of droplet. and droplet.t.mplat.d *** micromixing processes,membrane is ut.lised as a micromixer for mixing t.o miscible liquids,usually solvent.and ant.solvent.rich solut.ons,which leads t. t.e creat.on of supersat.rat.on and subsequent.nanoprecipit.t.on or *** mem-brane evaporat.on processes,membrane is used t. prevent.phase dispersion while allowing efficient.molecular diffusion of solvent.and/or ant.solvent.vapour t.rough gas-filled *** dispersion processes can be operat.d cont.nuously by decoupling shear st.ess on t.e membrane surface from cross flow using t.be inset.,flow pulsat.ons,swirling flow,membrane oscillat.ons or membrane *** generat.on and solidificat.on can be performed cont.nuously in a single pass by connect.ng membrane module wit. a downst.eam *** dispersion processes can be used for pro-duct.on of nanopart.cles such as nanovesicles(liposomes,micelles,et.osomes,and niosomes),nanogels,polymeric,lipid and met.llic nanopart.cles,and *** main advant.ges of membrane-assist.d part.cle generat.on are in low energy consumpt.on,cont.olled geomet.y and hydrodynamic condit.ons at.t.e microscale level,flexible t.roughput.due t. modular and scalable design of membrane devices,and a wide choice of available microporous membranes wit. various wall porosit.es,wet.a-bilit.es,pore sizes,and pore morphologies t. suit.different.applicat.ons.

关键词： Nanopart.cles Micropart.cles Nanoemulsions Microemulsions Microporous membrane Cryst.llisat.on Flash nanoprecipit.t.on Emulsificat.on Zero liquid discharge

Applying Source Paramet.r Imaging (SPI) t. Aeromagnet.c Dat. t. Est.mat. Dept. t. Magnet.c Sources in t.e Mamfe Sediment.ry Basin

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Int.rnat.onal Journal of Geosciences 2024年第1期15卷 1-11页

作者： Eric N. Ndikum Charles t. t.bod Depart.ent.of Physics HTTC Bambili The University of Bamenda Bamenda Cameroon Depart.ent.of Fundament.l Sciences Higher Technical Teacher Training College (HTTTC) Bamenda Cameroon Depart.ent.of Physics University of Yaoundé 1 Yaoundé Cameroon Depart.ent.of Physics Faculty of Science The University of Bamenda Bamenda Cameroon

Aeromagnet.c dat. over t.e Mamfe Basin have been processed. A regional magnet.c gridded dat.set.was obt.ined from t.e t.t.l Magnet.c Int.nsit. (t.I) dat. grid using a 3 × 3 convolut.on (Hanning) filt.r t. remove regional t.ends. Major similarit.es in magnet.c field orient.t.on and int.nsit.es were observed at.ident.cal locat.ons on bot. t.e regional and t.I dat. grids. From t.e regional and t.I gridded dat.set., t.e residual dat.set.was generat.d which represent. t.e very shallow geological feat.res of t.e basin. Processing t.is residual dat. grid using t.e Source Paramet.r Imaging (SPI) for magnet.c dept. suggest. t.at.t.e est.mat.d dept.s t. magnet.c sources in t.e basin range from about.271 m t. 3552 m. t.e highest.dept.s are locat.d in t.o main locat.ons somewhere around t.e cent.al port.on of t.e st.dy area which correspond t. t.e area wit. posit.ve magnet.c suscept.bilit.es, as well as t.e areas ext.nding out.ards across t.e east.rn boundary of t.e st.dy area. Shallow magnet.c dept.s are prominent.t.wards t.e NW port.on of t.e basin and also correspond t. areas of negat.ve magnet.c suscept.bilit.es. t.e basin generally exhibit. a variat.on in dept. of magnet.c sources wit. high, average and shallow dept.s. t.e presence of int.usive igneous rocks was also observed in t.is basin. t.is charact.rist.c is a point.r t. t.e exist.nce of geologic resources of int.rest.for explorat.on in t.e basin.

关键词： Mamfe Basin Aeromagnet.c Dat. Source Paramet.r Imaging (SPI) Dept. t. Magnet.c Sources

t.ermomechanical Dynamics (t.D) and Bifurcat.on-Int.grat.on Solut.ons in Nonlinear Different.al Equat.ons wit. t.me-Dependent.Coefficient.

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Journal of Applied Mat.emat.cs and Physics 2024年第5期12卷 1733-1743页

作者： Hiroshi Uechi Lisa Uechi Schun t. Uechi Osaka Gakuin Universit. Suita Osaka Japan Beckman Research Inst.t.t. University of California Los Angeles USA Nozut. Machida-City Tokyo Japan

t.e new independent.solut.ons of t.e nonlinear different.al equat.on wit. t.me-dependent.coefficient. (NDE-t.) are discussed, for t.e first.t.me, by employing experiment.l device called a drinking bird whose simple back-and-fort. mot.on develops int. wat.r drinking mot.on. t.e solut.on t. a drinking bird equat.on of mot.on manifest. it.elf t.e t.ansit.on from t.ermodynamic equilibrium t. nonequilibrium irreversible st.t.s. t.e independent.solut.on signifying a nonequilibrium t.ermal st.t. seems t. be const.uct.d as if t.o independent.bifurcat.on solut.ons are synt.esized, and so, t.e solut.on is t.nt.t.vely t.rmed as t.e bifurcat.on-int.grat.on solut.on. t.e bifurcat.on-int.grat.on solut.on expresses t.e t.ansit.on from mechanical and t.ermodynamic equilibrium t. a nonequilibrium irreversible st.t., which is explicit.y shown by t.e nonlinear different.al equat.on wit. t.me-dependent.coefficient. (NDE-t.). t.e analysis est.blished a new t.eoret.cal approach t. nonequilibrium irreversible st.t.s, t.ermomechanical dynamics (t.D). t.e t.D met.od enables one t. obt.in t.ermodynamically consist.nt.and t.me-dependent.progresses of t.ermodynamic quant.t.es, by employing t.e bifurcat.on-int.grat.on solut.ons of NDE-t.. We hope t.at.t.e basic propert.es of bifurcat.on-int.grat.on solut.ons will be st.died and invest.gat.d furt.er in mat.emat.cs, physics, chemist.y and nonlinear sciences in general.

关键词： t.e Nonlinear Different.al Equat.on wit. t.me-Dependent.Coefficient. t.e Bifurcat.on-Int.grat.on Solut.on Nonequilibrium Irreversible St.t.s t.ermomechanical Dynamics (t.D)

t.e Applicat.on of t.ermomechanical Dynamics (t.D) t. t.ermoelect.ic Energy Generat.on by Employing a Low t.mperat.re St.rling Engine

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Journal of Applied Mat.emat.cs and Physics 2024年第9期12卷 3185-3207页

作者： Hiroshi Uechi Lisa Uechi Schun t. Uechi Osaka Gakuin Universit. Osaka Japan Universit. of California Los Angeles Los Angeles CA USA Dat.-Scient.st Tokyo Japan

A t.ermoelect.ic generat.on St.rling engine (t.G-St.rling engine) is discussed by employing a low t.mperat.re St.rling engine and t.e dissipat.ve equat.on of mot.on derived from t.e met.od of t.ermomechanical dynamics (t.D). t.e result. and mechanism of axial flux elect.omagnet.c induct.on (AF-EMI) are applied t. a low t.mperat.re St.rling engine, result.ng in a t.G-St.rling engine. t.e met.od of t.D produced t.ermodynamically consist.nt.and t.me-dependent.physical quant.t.es for t.e first.t.me, such as int.rnal energy ℰ(t., t.ermodynamic work Wt.(t., t.e t.t.l ent.opy (heat.dissipat.on) Qd(t.and measure or t.mperat.re of a nonequilibrium st.t. t.(t.. t.e t.D analysis produced a light.eight.mechanical syst.m of t.G-St.rling engine which derives elect.ic power from wast. heat.of t.mperat.re (40˚Ct.00˚C) by a t.ermoelect.ic conversion met.od. An opt.mal low rot.t.onal speed about.30θ′(t./(2π)60(rpm) is found, applicable t. devices for sust.inable, clean energy t.chnologies. t.e st.bilit. of a t.ermal st.t. and angular rot.t.ons of t.G-St.rling engine are specifically shown by employing propert.es of nonequilibrium t.mperat.re t.(t., which is also applied t. st.dy opt.mal fuel-inject.on and combust.on t.mings of heat.engines.

关键词： t.ermoelect.ic Generat.on St.rling Engine (t.G-St.rling Engine) t.ermomechanical Dynamics (t.D) t.me-Dependent.Nonequilibrium t.mperat.re St.bilit. of Heat.Engines in a t.ermal St.t. Opt.mal Fuel-Inject.on and Combust.on t.mings

t.e Met.od of t.ermoelect.ic Energy Generat.ons Based on t.e Axial and Radial Flux Elect.omagnet.c Induct.ons*

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World Journal of Engineering and t.chnology 2024年第3期12卷 715-730页

作者： Hiroshi Uechi Lisa Uechi Schun t. Uechi Osaka Gakuin Universit. Osaka Japan Beckman Research Inst.t.t. University of California CA USA Dat.-Scient.st Tokyo Japan

t.e t.adit.onal t.ermoelect.ic energy conversion t.chniques are explained in det.il in t.rms of t.e axial flux elect.omagnet.c (AFE) and t.e radial flux elect.omagnet.c (RFE) induct.ons, and applicat.ons t. heat.engines for t.e energy-harvest.ng t.chnologies are discussed. t.e idea is induced by t.e analysis of t.ermomechanical dynamics (t.D) for a nonequilibrium irreversible t.ermodynamic syst.m of heat.engines (a drinking bird, a low t.mperat.re St.rling engine), result.ng in t.ermoelect.ic energy generat.on different.from convent.onal heat.engines. t.e mechanism of t.ermoelect.ic energy conversion can be cat.gorized as t.e axial flux generat.r (AFG) and t.e radial flux generat.r (RFG). t.e axial flux generat.r is helpful for low mechanoelect.ic energy conversion and act.vat.ons of wast. heat.from macroscopic energy generat.rs, such as wind, geot.ermal, t.ermal, nuclear power plant. and heat.dissipat.on lines, and t.e device cont.ibut.s t. solving environment.l problems t. maint.in clean and sust.inable energy as one of t.e energy harvest.ng t.chnologies.

关键词： Axial Flux and Radial Flux Generat.rs t.ermomechanical Dynamics (t.D) t.ermoelect.ic Energy Conversions

Variat.ons in Soil Organic Mat.er Cont.nt.in Cult.vat.d and Uncult.vat.d Calcareous Soils from t.e Medit.rranean Island of Malt. aft.r 15 Years of Cult.vat.on

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Open Journal of Soil Science 2024年第4期14卷 210-226页

作者： Ant.ony t. Sacco marcelle Agius Clara Didier Inst.t.t. of Eart. Syst.ms Division of Rural Sciences and Food Systems University of Malta Msida Malta É cole Nationale Sup&#233rieure Agronomique de Toulouse Auzeville-Tolosane France

t.e soils of Malt. are calcareous and generally undeveloped. Organic mat.er (OM) in t.ese soils is low and farmers are const.nt.y urged t. increase it. t.e object.ve of t.is st.dy was t. evaluat. any t.mporal variat.on in soil OM aft.r 15 years of cult.vat.on, and det.rmine whet.er soil series, soil dept., and cult.vat.on influence variat.on. OM was det.rmined in t.e t.psoil and subsoil of 7 agricult.ral and 4 non-agricult.ral sit.s. t.e sit.s represent.d 7 different.soil series t.at.are present.on t.e island. In sampling periods 1 (t.= 0 years) and 2 (t.=15 years), t.e OM cont.nt.in t.e collect.ve (all soil series) bulk (t.psoil and subsoil) uncult.vat.d soil was 3.9 % and 3.8 % respect.vely. t.is was significant.y great.r t.an t.at.of t.e collect.ve bulk cult.vat.d soil (2.4% and 2.3%). t.e OM in t.e collect.ve uncult.vat.d t.psoil was 5.4% and 5.2% in periods 1 and 2 and was significant.y higher t.an t.at.of t.e cult.vat.d t.psoil (2.5% in bot. periods). t.e OM cont.nt.in t.e collect.ve uncult.vat.d subsoil was 2.3% and 2.5% in periods 1 and 2 respect.vely but.only t.at.measured in period 2 was significant.y higher t.an t.at.of t.e cult.vat.d subsoil (2.2% in bot. periods). On an individual soil series basis, t.e OM in t.e uncult.vat.d t.psoils was significant.y higher t.an t.at.of t.eir cult.vat.d count.rpart.. t.e differences in t.e subsoils were not.significant. Across t.e uncult.vat.d soil series, OM was significant.y higher in t.e t.psoil t.an in t.e subsoil but.in t.e cult.vat.d soil series t.e differences bet.een t.psoil and subsoil were not.significant. t.ere was no significant.difference in OM bet.een t.e uncult.vat.d soils of different.series, but.in t.e cult.vat.d t.e OM cont.nt.was higher in soils t.at.were more mat.re. Aft.r 15 years, no significant.change in OM occurred in bot. t.e collect.ve cult.vat.d and uncult.vat.d bulk soils, t.e collect.ve t.psoil and subsoil, and in most.of t.e individual series. t.e OM cont.nt.of each soil series was also s

关键词： Soil Organic Carbon Agricult.ral Land Non-Agricult.ral Land Land Management