检索结果-南通市图书馆

Acta Mechanica Solida Sinica 2023年第2期36卷 230-240页

作者： Meng-yuan Hao Hu Ding Xiao-Ye mao Li-Qun Chen Shanghai Key Laboratory of Mechanics in Energy Engineering School of Mechanics and Engineering ScienceShanghai UniversityShanghai 200072China

Usually,the stability analysis of pipes with pulsating flow velocities is for rigidly constrained pipes or cantilevered *** this paper,the effects of elastic constraints on pipe stability and nonlinear responses under pulsating velocities are investigated.A mechanical model of a fluid-conveying pipe under the constraints of elastic clamps is established.A partial differentialintegral nonlinear equation governing the lateral vibration of the pipe is *** natural frequencies and mode functions of the pipe are ***,the stable boundary and nonlinear steady-state responses of the parametric vibration for the pipe are established ***,the analytical solutions are verified *** results of this work reveal some interesting *** is found that the elastic constraint stiffness in the direction perpendicular to the axis of the pipe does not affect the critical flow velocity of the ***,the constraint stiffness has a significant effect on the instability boundary of the pipe with pulsating flow ***,an increase in the stiffness of the constraint increases the instable region of the pipe under parametric ***,when the constraint stiffness is increased,the steady-state response amplitude of the nonlinear vibration for the pipe is significantly ***,the effects of the constraint stiffness on the instable region and vibration responses of the fluid-conveying pipe are different when the flow velocity is pulsating.

关键词： Pipe conveying fluid Elastic boundary Stability Nonlinear dynamics Parametric vibration Multi-scale method

Denosumab combined with immunotherapy,radiotherapy,and granulocyte-macrophage colony-stimulating factor for the treatment of metastatic nasopharyngeal carcinoma:A case report

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2025年第2期16卷 130-143页

作者： Wei-Wu Chen Yue-Hong Kong Li-yuan Zhang Center for Cancer Diagnosis and Treatment The Second Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Bone is a major site of metastasis in nasopharyngeal carcinoma(NPC).Recently,nuclear factor kappa-beta ligand(RANKL)inhibitors have garnered attention for their ability to inhibit osteoclast formation and bone resorption,as well as their potential to modulate immune functions and thereby enhance the efficacy of programmed cell death protein 1(PD-1)inhibitor *** SUMMARY We present a case of a patient with NPC who developed sternal stalk metastasis and multiple bone metastases with soft tissue invasion following radical chemoradiotherapy and targeted *** to chemotherapy,the patient experienced severe bone marrow suppression and opted out of further chemotherapy ***,the patient received combination therapy,including RANKL inhibitors(denosumab)alongside PD-1,radiotherapy,and granulocyte-macrophage colonystimulating factor(PRaG)therapy(NCT05435768),and achieved 16 months of progression-free survival and more than 35 months of overall survival,without encountering any grade 2 or higher treatment-related adverse *** Denosumab combined with PRaG therapy could be a new therapeutic approach for the second-line treatment in patients with bone metastases.

关键词： Nasopharyngeal carcinoma Bone metastasis Radiotherapy Programmed cell death protein 1 inhibitors Denosumab Case report

ON THE HOMOCLINIC ORBITS IN A CLASS OF TWO-DEGREE-OF-FREEDOM SYSTEMS UNDER THE RESONANCE CONDITIONS

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2001年第3期22卷 340-352页

作者： WANG mao-nan(王茂南) XU Zhen-yuan(徐振源) Mathematics and Physics Institute Wuxi University of Light Industry Wuxi 214036 P R China Mathematics and Physics Institute Wuxi University of Light Industry Wuxi 214036 P R China

A class of two-degree-of-freedom systems in resonance with an external, parametric excitation is investigated, the existence of the periodic solutions locked to Omega is proved by the use of the method of multiple scales. This systems can be transformed into the systems of Wiggins under some conditions. A calculating formula which determines the existence of homoclinic orbits of the systems is given.

关键词： a two-degree-of-freedom system method of multiple scales periodic solution homoclinic orbit chaos

Structural characteristics and mechanism of hydrogen-induced disproportionation of the ZrCo alloy

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2012年第11期19卷 1010-1015页

作者： xiu-mei Guo Shu-mao Wang Xiao-peng Liu Zhi-nian Li Jian-hua Ye Hui-ping yuan Li-jun Jiang Energy Material and Technology Institute General Research Institute for Nonferrous Metals Beijing 100088 China

The intermetallic compound ZrCo was prepared, and its hydrogen-induced disproportionation in hydrogen desorption processes was investigated. The hydrogenation-dehydrogenation thermodynamics of the ZrCo alloy was evaluated by pressure-composition isotherm measurements at different temperatures. The kinetic processes of hydrogen-induced disproportionation at different temperatures under certain pressures were detailedly studied. The disproportionation rate of the ZrCo alloy increased with the increases of temperature and initial hy- drogen pressure under experimental conditions. However, the maximum attainable extent of disproportionation did not change much with an increase in temperature or initial hydrogen pressure. The crystallographic structure analysis of the ZrCo alloy combining with its corre- sponding dehydrogenation kinetic curves under the conditions of an initial hydrogen pressure of 0.2 MPa and a temperature of 723 K indi- cated that the basic process of disproportionation reactions was composed of four stages： rapid dehydrogenation of ZrCoH3, equilibrium of dehydrogenation, simultaneity of dehydrogenation and disproportionation, and completion of disproportionation.

关键词： zirconium compounds cobalt compounds hydrogenation dehydrogenation structural analysis thermodynamics

Study on the performance of TEG with heat transfer enhancement using graphene-water nanofluid for a TEG cooling system

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2017年第8期60卷 1168-1174页

作者： LI YiHuai WU ZiHua XIE HuaQing XING JiaoJiao mao JianHui WANG yuan yuan LI Zhen School of Environmental and Materials Engineering College of EngineeringShanghai Polytechnic University School of Environmental and Chemical Engineering Shanghai University

Improvement of the heat transfer effect of cold side of a thermoelectric generator(TEG) is one of the approaches to enhance the performance of the TEG *** a new type of heat transfer media,nanofluids can enhance the heat transfer performance of working liquid *** this study,the performance of a commercial TEG with graphene-water(GW) nanofluid as coolants in a minichannel heat exchanger is investigated experimentally at low *** results show that the output power of TEG increases with the flow rate under 950 mL/***,the fluid flow rate has no influence on the output power of TEG with higher flow rate(larger than 950 mL/min) when the heat transfer dynamic balance state of the system is *** optimal concentration and flow rate of nanofluid are 0.1 wt%and 950 mL/min,*** the optimal conditions,the improved voltage,output power and conversion efficiency with GW nanofluid applied in the cooling system are increased by11.29%,21.55%and 3.5%in comparison with those with only water applied,respectively.

关键词： thermoelectric generation graphene-water nanofluid power generation

Modification of total and phosphorus mineralizing bacterial communities associated with Zea mays *** plant development and fertilization regimes

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2021年第11期20卷 3026-3038页

作者： XIN yuan-yuan Anisur RAHMAN LI Hui-xiu XU Ting DING Guo-chun LI Ji College of Resources and Environmental Sciences China Agricultural UniversityBeijing 100193P.R.China Organic Recycling Institute(Suzhou) China Agricultural UniversitySuzhou 215128P.R.China

Harnessing the rhizospheric microbiome,including phosphorus mineralizing bacteria(PMB),is a promising technique for maintaining sustainability and productivity in intensive agricultural ***,it is unclear as to which beneficial taxonomic group populations in the rhizosphere are potentially associated with the changes in soil microbiomes shifted by fertilization ***,we analyzed the diversity and community structure of total bacteria and PMB in the rhizosphere of maize(Zea mays L.)grown in soils under 25 years of four fertilization regimes(compost,biocompost,chemical,or nonfertilized)via selective culture and Illumina sequencing of the 16S rRNA *** development explained more variations(29 and 13%,respectively)in the composition of total bacteria and PMB in the rhizosphere of maize than the different fertilization *** those genera enriched in the rhizosphere of maize,the relative abundances of Oceanobacillus,Bacillus,Achromobacter,Ensifer,Paracoccus,Ramlibacter,and Luteimonas were positively correlated with those in the bulk *** relative abundance of Paracoccus was significantly higher in soils fertilized by compost or biocompost than the other *** results were also observed for PMB affiliated with Ensifer,Bacillus,and *** plant development was the major factor in shaping the rhizospheric microbiome of maize,fertilization regimes might have modified beneficial rhizospheric microbial taxa such as Bacillus and Ensifer.

关键词： organic fertilization bacterial diversity phosphorus mineralizing bacteria(PMB) Zea mays L. rhizosphere

Experimental study of hydraulic fracture propagation with multi-cluster in-plane perforations in a horizontal well

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第5期21卷 3258-3270页

作者： Xian Shi yuan-yuan Yang Xiang-Wei Kong Qi Gao Shu Jiang Hai-Jun mao College of Petroleum Engineering China University of Petroleum(East China) State Key Laboratory of Deep Oil and Gas China University of Petroleum(East China) School of Petroleum Engineering Yangtze University Key Laboratory of Drilling and Production Engineering for Oil and Gas School of Engineering The University of Western Australia Key Laboratory of Tectonics and Petroleum Resources of Ministry of Education School of Earth Resources China University of Geosciences State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil Mechanics Chinese Academy of Sciences

Tri-axial fracturing studies were carried out to understand the impact of lateral mechanical parameters on fracture propagation from multiple in-plane perforations in horizontal wells. Additionally, the discussion covered the effects of geology, treatment, and perforation characteristics on the non-planar propagation behavior. According to experimental findings, two parallel transverse fractures can be successfully initiated from in-plane perforation clusters in the horizontal well because of the in-plane perforation, the guide nonuniform fishbone structure fracture propagation still can be exhibited. The emergence of transverse fractures and axial fractures combined as complex fractures under low horizontal principal stress difference and large pump rate conditions. The injection pressure was also investigated, and the largest breakdown pressure can be also found for samples under these *** increase in perforation number or decrease in the cluster spacing could provide more chances to increase the complexity of the target stimulated zone, thus affecting the pressure fluctuation. In a contrast, the increase in fracturing fluid viscosity can reduce the multiple fracture complexity. The fracture propagation is significantly affected by the change in the rock mechanical properties. The fracture geometry in the high brittle zone seems to be complicated and tends to induce fracture reorientation from the weak-brittle zone. The stress shadow effect can be used to explain the fracture attraction, branch, connection, and repulsion in the multiple perforation clusters for the horizontal *** increase in the rock heterogeneity can enhance the stress shadow effect, resulting in more complex fracture geometry. In addition, the variable density perforation and temporary plugging fracturing were also conducted, demonstrating higher likelihood for non-uniform multiple fracture propagation. Thus, to increase the perforation efficiency along the horizontal well, it is

关键词： Heterogeneous rock In-plane perforation Stress shadowing Tri-axial fracturing Multiple perforation clusters

Two New Antibacterial Iridoids from Patrinia rupestris

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2006年第3期17卷 337-340页

作者： xiu Ping YANG Cheng Shan yuan Zhong Jian JIA State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000

Two new iridoids （1 and 2） were isolated from the roots of Patrinia rupestris （Pail.） Juss. Their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited strong antibacterial activities ag... 详细信息

关键词： Patrinia rupestris Valerianaceae iridoids antibacterial activity.

In situ generation of biodegradable poly(p-dioxanone)microparticles by polymerization in supercritical carbon dioxide

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2011年第12期22卷 1509-1512页

作者： Tian Qiang Wang xiu Li Zhao Jian yuan Hao State Key Lab of Electronic Films and Integrated Devices School of Microelectronics and Solid State Electronics University of Electronic Science and Technology of China Chengdu 610054 China Institute of Chemical Materials China Academy of Engineering Physics Mianyang 621900 China

Ring-opening suspension polymerization of p-dioxanone（PDO） in supercritical carbon dioxide（scCO_2） was investigated in the presence of poly（caprolactone）-perfluropolyether-poly（caprolactone）（PCL-PFPE-PCL）.The molecular weight,yield and particle morphology of poly（p-dioxanone）（PPDO） were *** stabilizer was effective to stabilize the ring-opening polymerization（ROP） of PDO in scCO_2,leading to the formation of resorbable microparticles in a＂one pot＂*** mean size of PPDO microparticles obtained from suspension polymerizations was sensitive to the rate of agitation and the stabilizer *** method to generate PPDO microparticles has overcome its unprocessable drawback with common organic solvents and provided new product form for biomedical applications.

关键词： Biodegradable Poly(p-dioxanone) Polymerization Stabilizer Microparticle

Effect of Sb dopant amount on the structure and electrocatalytic capability of Ti/Sb-SnO_2 electrodes in the oxidation of 4-chlorophenol

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2007年第11期19卷 1380-1386页

作者： KONG Jiang-tao SHI Shao-yuan ZHU xiu-ping NI Jin-ren Key Laboratory of Water and Sediment Sciences Ministry of Education of China Department of Environmental Engineering Peking University Beijing 100871 China State Key Laboratory of Biochemical Engineering Institute of Process Engineering Chinese Academy of Sciences Beijing 100080 China

Ti/Sb-SnO2 anodes were prepared by thermal decomposition to examine the influence of the amount of Sb dopant on the structure and electrocatalytic capability of the electrodes in the oxidation of 4-chlorophenol. The physicochemical properties of the Sb-SnO2 coating were markedly influenced by different amounts of Sb dopant. The electrodes, which contained 5% Sb dopant in the coating, presented a much more homogenous surface and much smaller mud-cracks, compared with Ti/Sb-SnO2 electrodes containing 10% or 15% Sb dopant, which exibited larger mud cracks and pores on the surface. However, the main microstructure remained unchanged with the addition of the Sb dopant. No new crystal phase was observed by X-ray diffraction （XRD）. The electrochemical oxidation of 4-chlorophenol on the Ti/SnO2 electrode with 5% Sb dopant was inclined to electrochemical combustion; while for those containing more Sb dopant, intermediate species were accumulated. The electrodes with 5% Sb dopant showed the highest efficiency in the bulk electrolysis of 4-chlorophenol at a current density of 20 mA/cm^2 for 180 min; and the removal rates of 4-chlorophenol and COD were 51.0% and 48.9%, respectively.

关键词： 4-chlorophenol cyclic voltammogram electrochemical oxidation Sb dopant Ti/Sb-SnO2 electrode