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Critical evaluation of transit policies in Lima,Peru;resilience of rail rapid transit(Metro)in a developing country

Green Energy and Intelligent Transportation 2024年第5期3卷 23-33页

作者： manuel jose martinez Representante Legal Instituto de Avance del Transporte Peruano EIRLCalle Schrader 179dpto.202Lima 41San BorjaLimaPeru

This paper evaluates rail transit within the context of the transit policies implemented in Lima,*** it reviews the implementation of rapid transit,and bus ***,it evaluates the outcomes of such policies by using Total Factor Productivity for policy effectiveness,Data Envelopment Analysis for rapid transit performance,and Generalized Cost of Travel for *** paper finds that implementation failed in enforcing key requirements for rail transit regarding penetration of CBD and short transfers to bus transit;and that the basic assumptions of bus reform did not hold regarding bus oversupply,bus congestion or bus *** paper also finds that outcomes of policies failed dramatically in achieving the planning goals;however,rail transit(Metro)shows high level of resilience in serving large ridership at high *** the other hand,bus reform was associated with a disproportionate increase of motorization,well over the effect of income growth or car attractiveness,and more related to the excessive reduction of bus transit capacity ill-advised from unproved bus reform *** paper recommends expanding rail rapid transit due to its intensive use of green renewable energy and its potential of demand growth if combined with modern Intelligent Transportation services,but this opportunity can be wasted without the proposed policy constraint to achieve lower Generalized Cost of Travel at any governmental intervention for bus reform,instead of just reducing bus transit capacity as ***,this paper recommends government to government contracts to build rail transit and to enforce proper planning.

关键词： Public transportation Bus rapid transit Rail transportation Bus transit Developing countries Resilient

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Non-redundant Contribution of the Plastidial FAD8 ω-3 Desatumse to Glycerolipid Unsatumtion at Different Temperatures in Arabidopsis

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Molecular Plant 2015年第11期8卷 1599-1611页

作者： Angela Roman Maria L. Hernandez Angel Soria-Garcia Sara Lopez-Gomollon Beatriz Lagunas Rafael Picorel jose manuel martinez-Rivas Miguel Alfonso Estacion Experimental de Aula Dei (EEAD-CSIC) Avda. Montanana 1005 50059 Zaragoza Spain Instituto de la Grasa (IG-CSIC) Campus Universidad Pablo de Olavide Building 46 Ctra. Utrera kin 1 41013 Seville Spain

Plastidial ω-3 desaturase FAD7 is a major contributor to trienoic fatty acid biosynthesis in the leaves of Arabidopsis plants. However, the precise contribution of the other plastidial ω-3 desaturase, FAD8, is poorly understood. Fatty acid and lipid analysis of several ω-3 desaturase mutants, including two insertion lines of AtFAD7 and AtFAD8, showed that FAD8 partially compensated the disruption of the AtFAD7 gene at 22℃, indicating that FAD8 was active at this growth temperature, contrasting to previous observations that circumscribed the FAD8 activity at low temperatures. Our data revealed that FAD8 had a higher selectivity for 18：2 acyl-lipid substrates and a higher preference for lipids other than galactolipids, particularly phosphatidylglycerol, at any of the temperatures studied. Differences in the mechanism controlling AtFAD7 and AtFAD8 gene expression at different temperatures were also detected. Confocal microscopy and biochemical analysis of FAD8-YFP over-expressing lines confirmed the chloroplast envelope localization of FAD8. Co-localization experiments suggested that FAD8 and FAD7 might be located in close vicinity in the envelope membrane. FAD8-YFP over-expressing lines showed a specific increase in 18：3 fatty acids at 22℃. Together, these results indicate that the function of both plastidial ω-3 desaturases is coordinated in a non-redundant manner.

关键词： Arabidopsis thaliana glycerolipid fatty acid FAD7 FAD8 plastid

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Unusual treatment of postoperative bleeding after cardiac surgery

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World Journal of Cardiovascular Diseases 2013年第5期3卷 377-379页

作者： José Rubio-Alvarez Juan Sierra-Quiroga Belén Adrio-Nazar Laura Reija López ángela Granda Bauza Carola Rubio Taboada jose manuel martinez-Cereijo Department of Cardiac Surgery Universitary Hospital Santiago de Compostela Santiago Spain Department of Vascular Surgery Universitary Hospital of Elche Alicante Spain

A young patient was presented to the emergency department with chest pain and palpitations. A transthoracic echocardiogram showed a right atrial mass. Coronary angiography showed a right coronary artery with collateral circulation to a large mass. The tumor could only be partially resected and the patient experienced persistent postoperative bleeding. We performed a new right coronary artery angiography which showed an important free extravasation of contrast into the pericardium through the collateral circulation. Using covered stents, the bleeding was controlled. The pathological examination performed later revealed a primary cardiac angiosarcoma. After asymptom-free survival of 14 months the patient presented bone metastases.

关键词： Angiosarcoma Coronary Stenting Postoperative Bleeding

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软组织封闭术在美学区域单颗牙缺失种植修复和引导骨组织再生中的应用

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中国口腔医学继续教育杂志 2018年第5期21卷 257-268页

作者： Bruno Negri Otto Zuhr Stefan Fickl Xavier Rodriguez Ciurana jose manuel Navarro martinez Victor Mendez Blanco 黎艳珊(译) 滕伟(审) 不详中山大学光华口腔医学院·附属口腔医院 510000

目的:即便是对牙拔除术后的生物学效应有全面的了解,前牙的种植修复仍被认为是十分复杂的。前牙美学种植修复的目标是唇侧的软组织和龈乳头保持稳定。如何处理新鲜拔牙创以最大限度保存牙槽嵴是临床医师在每天的临床实践中都要面对的一... 详细信息

目的:即便是对牙拔除术后的生物学效应有全面的了解,前牙的种植修复仍被认为是十分复杂的。前牙美学种植修复的目标是唇侧的软组织和龈乳头保持稳定。如何处理新鲜拔牙创以最大限度保存牙槽嵴是临床医师在每天的临床实践中都要面对的一个问题。保存牙槽嵴轮廓往往益于后续治疗的实施。材料与方法:本文将通过3个病例来进行讲述这些技术的应用。结果:软组织封闭术和位点保存技术结合即刻种植、早期种植、延期种植对于单颗牙的修复有重要意义。然而,在不同条件下选择牙槽嵴保存技术的效应仍需进一步明确。

关键词：种植修复前牙美学引导骨组织再生牙缺失软组织封闭术保存技术生物学效应

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Contributions to data transmission at critical moments on unmanned aerial vehicles

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Chinese Journal of Aeronautics 2023年第8期36卷 247-257页

作者： jose Enrique RODRIGUEZ David SEGURADO manuel SANCHEZ jose Javier martinez Rafael GONZALEZ National Institute of Aerospace Technology Madrid 28850Spain Department of Computer Science University of AlcalaAlcala de HenaresMadrid 28054Spain

As for unmanned aircraft, the knowledge of the aircraft performance is directly related with the navigation, guidance, and control system programming. Therefore, the measured data in each phase of the flight must be sufficiently precise to obtain a good characterization of *** article proposes new methods of sending information to ground, which make it possible to know the aircraft behavior accurately, and for this purpose, four contributions have been made for ALO(Avión Ligero de Observación, Spanish acronym for Light Observation Aircraft). Currently, the characterization is based on data obtained at ten samples per second, insufficient to acquire detailed knowledge of what happened during the whole flight of an aircraft. As a result of these contributions, many more samples per second of accelerations and angular velocities are obtained at the most critical moments of the flight, such as takeoff or landing. Among the improvements included are data compression techniques, providing references to locate the measured data in time and identifying labels of each parameter.

关键词： Critical moments Data transmission Datacompression tech-niques Radio-modem Recommended Standard 232(RS-232) Unmannedaerial vehicle

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Acoustic streaming and Sun's meridional circulation

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Research in Astronomy and Astrophysics 2016年第9期16卷 101-106页

作者： jose manuel Valverde Faculty of Physics University of Seville

A vast number of physical processes involving oscillations of a bounded viscous fluid are relevantly influenced by acoustic streaming. When this happens a steady circulation of fluid develops in a thin boundary adjacent to the interface. Some examples are refracted sound waves, a fluid inside a spherical cavity undergoing torsional oscillations or a pulsating liquid droplet. Steady streaming around circular interfaces consists of a hemispherically symmetric recirculation of fluid from the equatorial plane to the polar axes closely resembling the meridional circulation pattern observed in the Sun＇s convection zone that determines the solar cycle. In this paper, it is argued that the acoustic pulsations exhibited by the Sun would lead to acoustic streaming in the boundary of the convection zone. A simple estimation using a typical dominant frequency of 3 mHz and the observed surface oscillation amplitude yields a steady streaming velocity Us - 10 m s^-1, which is on the order of the meridional circulation velocity observed in the Sun＇s convection zone.

关键词： Sun general -- Sun helioseismology -- Sun granulation -- Sun oscillations -- Sun fun-damental parameters -- Sun activity

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Magnetic field assisted fluidization:A modified Richardson-Zaki equation

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China Particuology 2007年第1期5卷 61-70页

作者： jose manuel Valverde Antonio Castellanos Faculty of Physics Universidad de Sevilla Avenida Reina Mercedes s/n 41012 Sevilla Spain

Magnetic particles can be uniformly fluidized by coupling the gas flow with an externally imposed magnetic field. Interparticle forces generated by the magnetic field cause aggregation of the particles in chain-like structures preferentially oriented along the magnetic field lines. In the present paper, we study the implications of the formation of these special types of aggregates on the empirical Richardson-Zaki （RZ） equation, originally proposed to describe the expansion of fluidized beds of non-aggregated particles. We have addressed two important issues, namely the flow regime, which is a function of the size of the aggregates, and the effect of shape and orientation of the chain-like aggregates with respect to gas flow on fluid drag. We propose a modified RZ equation （MRZE） in which the velocity scale, given by the terminal settling velocity of the individual aggregates, and the RZ exponent are predetermined as a function of the chain length. The chain length depends on the ratio of the magnetic energy to gravitational energy, and is estimated from the magnetic field intensity, and particle magnetization, size and density. Predictions of the MRZE are successfully compared with published results in the literature on the expansion of magnetic particles in the presence of externally applied magnetic fields.

关键词： Fluidization Geldart B Magnetic particles Aggregation Richardson-Zaki equation

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Tropical tree community composition and diversity variation along a volcanic elevation gradient

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Journal of Mountain Science 2022年第12期19卷 3475-3486页

作者： Ruben martinez-CAMILO manuel martinez-MELENDEZ Nayely martinez-MIELENDEZ Derio Antonio JIMENEZ-LOPEZ Mauricio jose-RIOS Unidad Villa Corzo Facultad de IngenieríaUniversidad de Ciencias y Artes de Chiapas30520 Villa CorzoChiapasMexico Instituto de Ciencias Biológicas Universidad de Ciencias y Artes de Chiapas29039 Tuxtla GutiérrezChiapasMexico Eizia A.C. 29045 Tuxtla GutiérrezChiapasMexico Departamento de Conservación de la Biodiversidad El Colegio de la Frontera Sur29290 San Cristóbal de las CasasChiapasMexico Orquidiario y Jardín Botánico de Comitán Secretaría de Medio Ambiente e Historia Natural30106 Comitán de DomínguezChiapasMexico Instituto de Investigación en Gestión de Riesgos y Cambio Climático Universidad de Ciencias y Artes de Chiapas29039 Tuxtla GutiérrezChiapasMexico

Unraveling the factors that determine variation of diversity in tropical mountain systems is a topic for debate in plant *** is especially true in areas where topography is complex due to volcano elevational gradients and where forests are vulnerable to human *** this study we used a set of climatic(temperature,rainfall,and radiation solar),topographic(elevation,slope aspect,and slope orientation)and human disturbance variables to determine their effect on diversity and composition patterns of a tree community,considering three slope aspects of a tropical volcano in southeastern *** sampled trees in seventy 0.1-ha plots distributed on three slope aspects of the Tacanávolcano along an elevational gradient of 1500 to 2500 *** determined diversity patterns(general tree richness,exponential of Shannon index,and pioneer species richness)with linear regression models,and for beta diversity,we used a dissimilarity index(within and between elevational bands 100 m wide).The effect of a set of environmental and human disturbance variables on tree diversity and community composition was analyzed with general linear models and multivariate analyses,*** registered 2,949 individual trees belonging to 176 species and *** average species richness and alpha diversity per plot were 13(standard deviation±6)and 9(±5),*** tree richness and alpha diversity increased in the middle part(unimodal patterns)of the elevational gradient,but pioneer species richness decreased linearly with *** variance explained by general linear models was greater in richness(32%)than in alpha diversity(25.3%).The most important predictor variables were temperature(elevational gradient),which explained the unimodal pattern(richness and alpha diversity increase at intermediate levels of temperature),and slope orientation,which explained the increase in richness and alpha diversity toward the geographic *** temperature had a signific

关键词： Composition Environmental gradient Tree diversity patterns Tropical humid cloud forest Tropical volcanoes

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Liquid biopsy approach to pancreatic cancer

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World Journal of Gastrointestinal Oncology 2021年第10期13卷 1263-1287页

作者： Sonia Perales Carolina Torres Cristina Jimenez-Luna jose Prados Joaquina martinez-Galan jose manuel Sanchez-Manas Octavio Caba Department of Biochemistry and Molecular Biology I Faculty of SciencesUniversity of GranadaGranada 18071Spain Department of Biochemistry and Molecular Biology III and Immunology Faculty of SciencesUniversity of GranadaGranada 18071Spain Institute of Biopathology and Regenerative Medicine(IBIMER) Center of Biomedical Research(CIBM)University of GranadaGranada 18100Spain Department of Medical Oncology Hospital Universitario Virgen de las NievesGranada 18011Spain School for International Postgraduate Studies University of GranadaGranada 18071Spain

Pancreatic cancer(PC)continues to pose a major clinical *** has been little improvement in patient survival over the past few decades,and it is projected to become the second leading cause of cancer mortality by *** dismal 5-year survival rate of less than 10%after the diagnosis is attributable to the lack of early symptoms,the absence of specific biomarkers for an early diagnosis,and the inadequacy of available *** patients are diagnosed when the disease has already metastasized and cannot be *** interception is vital,actively intervening in the malignization process before the development of a full-blown advanced *** early diagnosis of PC has a dramatic impact on the survival of patients,and improved techniques are urgently needed to detect and evaluate this disease at an early *** is difficult to obtain tissue biopsies from the pancreas due to its anatomical position;however,liquid biopsies are readily available and can provide useful information for the diagnosis,prognosis,stratification,and follow-up of patients with PC and for the design of individually tailored *** aim of this review was to provide an update of the latest advances in knowledge on the application of carbohydrates,proteins,cell-free nucleic acids,circulating tumor cells,metabo-lome compounds,exosomes,and platelets in blood as potential biomarkers for PC,focusing on their clinical relevance and potential for improving patient outcomes.

关键词： Pancreatic cancer Biomarkers Liquid biopsy Clinical management Cancer interception Cancer monitoring

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Contrasting size-dependent life history strategies of an insular lizard

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Current Zoology 2020年第6期66卷 625-633页

作者： Andreu Rotger jose manuel Igual Giacomo Tavecchia Animal Demography and Ecology Unit GEDAIMEDEA(CSIC-UIB)c M.Marques 2101790EsporlesSpain

In many species with continuous growth,body size is an important driver of life-history tactics and its relative importance is thought to reflect the spatio-temporal variability of selective *** developed a deterministic size-dependent integral projection model for 3 insular neighboring lizard populations with contrasting adult body sizes to investigate how size-related selective pressures can influence lizard life-history *** each population,we broke down differences in population growth rates into contributions from size-dependent body growth,survival,and feeundity.A life table response experiment(LTRE)was used to compare the population dynamics of the 3 populations and quantify the contributions of intrinsic demographic coefficients of each population to the population growth rate(z).Perturbation analyses revealed that the largest adults contributed the most to the population growth rate,but this was not true in the population with the smallest adults and size-independent *** we were not able to identify a single factor responsible for this difference,the combination of the demographic model on a continuous trait coupled with an LTRE analysis revealed how individuals from sister populations of the same species follow different life strategies and showed different compensatory mechanisms among survival,individual body growth,and *** results indicate that body size can play a contrasting role even in closely-related and closely-spaced populations.

关键词： body size capture-recapture integral projection model Lilfords lizard size-dependent mortality

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