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Can We Capitalize on Central Nervous System Plasticity in Young Athletes to Inoculate Against Injury?

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Journal of Science in Sport and Exercise 2020年第4期2卷 305-318页

作者： Jed A.Diekfuss Jennifer A.Hogg Dustin R.Grooms Alexis B.Slutsky-Ganesh Harjiv Singh Scott Bonnette manish anand Gary B.Wilkerson Gregory D.Myer The SPORT Center Division of Sports MedicineCincinnati Children’s Hospital Medical Center3333 Burnet AvenueMLC 10001CincinnatiOH 45229USA Department of Health and Human Performance The University of Tennessee ChattanoogaChattanoogaTNUSA Ohio Musculoskeletal and Neurological Institute Ohio UniversityAthensOHUSA Division of Athletic Training School of Applied Health Sciences and WellnessCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Division of Physical Therapy School of Rehabilitation and Communication SciencesCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Department of Kinesiology The University of North Carolina GreensboroGreensboroNCUSA Department of Kinesiology and Nutrition Sciences University of NevadaLas VegasLas VegasNVUSA Departments of Pediatrics and Orthopaedic Surgery University of CincinnatiCincinnatiOHUSA The Micheli Center for Sports Injury Prevention WalthamMAUSA

There are numerous physical,social,and psychological benefits of exercise,sport and play for youth ***,dynamic activities come with a risk of injury that has yet to be abated,warranting novel therapeutics to promote injury-resistance and to keep an active lifestyle throughout the *** purpose of the present manuscript was to summarize the extant literature and potential connecting framework regarding youth brain development and neuroplasticity associated with musculoskeletal *** review provides the foundation for our proposed framework that utilizes the OPTIMAL(Optimizing Performance Through Intrinsic Motivation and Attention for Learning)theory of motor learning to elicit desir-able biomechanical adaptations to support injury prevention(injury risk reduction),rehabilitation strategies,and exercise performance for youth physical activity and play across all facets of sport(Prevention Rehabilitation Exercise Play;PREP).We conclude that both young male and females are ripe for OPTIMAL PREP strategies that promote desirable movement mechanics by leveraging a unique time window for which their heightened state of central nervous system plasticity is capable of enhanced adaptation through novel therapeutic interventions.

关键词： Musculoskeletal Motor learning Neuroplasticity Development

Practical Training Strategies to Apply Neuro-Mechanistic Motor Learning Principles to Facilitate Adaptations Towards Injury-Resistant Movement in Youth

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Journal of Science in Sport and Exercise 2021年第1期3卷 3-16页

作者： Jed A.Diekfuss Scott Bonnette Jennifer A.Hogg Christopher Riehm Dustin R.Grooms Harjiv Singh manish anand Alexis B.Slutsky-Ganesh Gary B.Wilkerson Gregory D.Myer The SPORT Center Division of Sports MedicineCincinnati Children’s Hospital Medical Center3333 Burnet AvenueMLC 10001CincinnatiOH 45229USA Department of Health and Human Performance The University of Tennessee ChattanoogaChattanoogaTNUSA Ohio Musculoskeletal and Neurological Institute Ohio UniversityAthensOHUSA Division of Athletic Training School of Applied Health Sciences and WellnessCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Division of Physical Therapy School of Rehabilitation and Communication SciencesCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Department of Kinesiology and Nutrition Sciences University of NevadaLas VegasNVUSA Department of Kinesiology The University of North Carolina at GreensboroGreensboroNCUSA Departments of Pediatrics and Orthopaedic Surgery University of CincinnatiCincinnatiOHUSA The Micheli Center for Sports Injury Prevention WalthamMAUSA

Youth may be particularly responsive to motor learning training strategies that support injury-resistant movement mechanics in youth for prevention programs that reduce injury risk,injury rehabilitation,exercise performance,and play more gener-ally(Optimizing Performance Through Intrinsic Motivation and Attention for Learning Prevention Rehabilitation Exercise Play;OPTIMAL PREP)One purpose of the present manuscript was to provide clinical applications and tangible examples of how to implement the proposed techniques derived from OPTIMAL theory into PREP strategies for youth.A secondary purpose was to review recent advances in technology that support the clinical application of OPTIMAL PREP strategies without extensive resources/programming knowledge to promote evidence-driven tools that will support practitioner feedback *** majority of examples provided are within the context of anterior cruciate ligament(ACL)injury rehabilitation,but we emphasize the potential for OPTIMAL PREP strategies to be applied to a range of populations and training scenarios that will promote injury resistance and keep youth active and healthy.

关键词： Rehabilitation Prevention Exercise performance Technology

Targeted Application of Motor Learning Theory to Leverage Youth Neuroplasticity for Enhanced Injury-Resistance and Exercise Performance: OPTIMAL PREP

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Journal of Science in Sport and Exercise 2021年第1期3卷 17-36页

作者： Jed A.Diekfuss Dustin R.Grooms Jennifer A.Hogg Harjiv Singh Alexis B.Slutsky-Ganesh Scott Bonnette Christopher Riehm manish anand Katharine S.Nissen Gary B.Wilkerson Gregory D.Myer The SPORT Center Division of Sports MedicineCincinnati Children’s Hospital Medical Center3333 Burnet AvenueMLC 10001CincinnatiOH 45229USA Ohio Musculoskeletal and Neurological Institute Ohio UniversityAthensOHUSA Division of Athletic Training School of Applied Health Sciences and WellnessCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Division of Physical Therapy School of Rehabilitation and Communication SciencesCollege of Health Sciences and ProfessionsOhio UniversityAthensOHUSA Deparatment of Health and Human Performance The University of Tennessee ChattanoogaChattanoogaTNUSA Department of Kinesiology and Nutrition Sciences University of NevadaLas VegasNVUSA Department of Kinesiology The University of North Carolina at GreensboroGreensboroNCUSA Departments of Pediatrics and Orthopaedic Surgery University of CincinnatiCincinnatiOHUSA The Micheli Center for Sports Injury Prevention WalthamMAUSA

Youth athletes are ideal candidates for novel therapeutic motor learning interventions that leverage the plasticity of the central nervous system to promote desirable biomechanical *** summarize the empirical data supporting the three pillars of the Optimizing Performance Through Intrinsic Motivation and Attention for Learning(OPTIMAL)theory of motor learning and expand on potential neurophysiologic mechanisms that will support enhanced movement mechan-ics in youth to optimize prevention programs for reduced injury risk,injury rehabilitation,exercise performance,and play(Prevention Rehabilitation Exercise Play;PREP).Specifically,we highlight the role of motivational factors to promote the release of dopamine that could accelerate motor performance and learning ***,we detail the potential for an external focus of attention to shift attentional allocation and increase brain activity in regions important for sensorimotor integration to facilitate primary motor cortex *** manuscript serves to provide the most current data in support of the application of OPTIMAL PREP training strategies of the future.

关键词： Dopamine Musculoskeletal Exercise performance Motor behavior

Stock Prediction Based on Technical Indicators Using Deep Learning Model

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Computers, Materials & Continua 2022年第1期70卷 287-304页

作者： manish Agrawal Piyush Kumar Shukla Rajit Nair anand Nayyar Mehedi Masud Department of Computer Science&Engineering University Institute of TechnologyRajiv Gandhi Proudyogiki VishwavidyalayaBhopal-462033Madhya PradeshIndia Faculty of Department of Computer Science&Engineering University Institute of TechnologyRajiv Gandhi Proudyogiki VishwavidyalayaBhopal-462033Madhya PradeshIndia Faculty of Department of Computer Science&Engineering School of Engineering and TechnologyJagran Lakecity UniversityBhopal462026Madhya PradeshIndia Graduate School Duy Tan UniversityDa Nang550000Vietnam Faculty of Information Technology Duy Tan UniversityDa Nang550000Vietnam Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

Stock market trends forecast is one of the most current topics and a significant research challenge due to its dynamic and unstable *** stock data is usually non-stationary,and attributes are non-correlative to each *** traditional Stock Technical Indicators(STIs)may incorrectly predict the stockmarket *** study the stock market characteristics using STIs and make efficient trading decisions,a robust model is *** paper aims to build up an Evolutionary Deep Learning Model(EDLM)to identify stock trends’prices by using *** proposed model has implemented the Deep Learning(DL)model to establish the concept of *** analysis of the dataset of three most popular banking organizations obtained from the live stock market based on the National Stock exchange(NSE)-India,a Long Short Term Memory(LSTM)is *** datasets encompassed the trading days from the 17^(th) of Nov 2008 to the 15^(th) of Nov *** work also conducted exhaustive experiments to study the correlation of various STIs with stock price *** model built with an EDLM has shown significant improvements over two benchmark ML models and a deep learning *** proposed model aids investors in making profitable investment decisions as it presents trend-based forecasting and has achieved a prediction accuracy of 63.59%,56.25%,and 57.95%on the datasets of HDFC,Yes Bank,and SBI,*** indicate that the proposed EDLA with a combination of STIs can often provide improved results than the other state-of-the-art algorithms.

关键词： Long short term memory evolutionary deep learning model national stock exchange stock technical indicators predictive modelling prediction accuracy

A Concise Review of Surgical exposures for Revision Knee Arthroplasty

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Surgical Science 2012年第5期3卷 256-260页

作者： Ashish anand Raviraj Adala manish Kumar J. Vijay Kumar Srinivas Gautam Kodikal Consultant Orthopedic Surgeon Center for Joint Replacement Fortis Hospitals Bangalore India Junior Resident Center for Joint Replacement Fortis Hospitals Bangalore India Senior Resident Center for Joint Replacement Fortis Hospitals Bangalore India

Revision knee arthroplasty is fraught with complications such as delayed wound healing, arthrofibrosis, increased chances of infection, instability and extensor mechanism disruption. The key to avoiding these complications is to handle the soft tissue with care and to have an adequate surgical exposure at the same time. As the number of revisions has gone up, there has been a renewed interest in getting the basics right to have an adequate surgical exposure. Numerous surgical approaches have been proposed and subsequently modified. We present a concise review of the various surgical approaches for a revision knee replacement.

关键词： Knee Arthroplasty Revision Exposures

Genetic gains with genomic versus phenotypic selection for drought and waterlogging tolerance in tropical maize(Zea mays L.)

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The Crop Journal 2021年第6期9卷 1438-1448页

作者： Reshmi Rani Das Madhumal Thayil Vinayan Kaliyamoorthy Seetharam manish Patel Ramesh Kumar Phagna Shyam Bir Singh Jai Prakash Shahi Akashi Sarma Nagendra Sarma Barua Raman Babu Pervez Haider Zaidi International Maize and Wheat Improvement Center(CIMMYT) ICRISAT CampusPatancheru 502324HyderabadIndia Main Maize Research Station Anand Agriculture UniversityAnand 388001GujaratIndia ICAR-Indian Institute of Maize Research Ludhiana141001BiharIndia Institute of Agricultural Sciences Banaras Hindu UniversityVaranasi 221005Uttar PradeshIndia Assam Agricultural University Jorhat 785013AssamIndia

Erratic rainfall often results in intermittent drought and/or waterlogging and limits maize(Zea mays L.)productivity in many parts of the Asian *** climate-resilient maize germplasm possessing tolerance to these key abiotic stresses without a yield penalty under optimal growing conditions is a challenge for breeders working in stress-vulnerable agro-ecologies in the *** stress-resilient maize for rainfed stress-prone ecologies is identified as one of the priority areas for CIMMYT-Asia maize *** applied rapid cycle genomic selection(RCGS)on two multiparent yellow synthetic populations(MYS-1 and MYS-2)to improve grain yield simultaneously under drought and waterlogging conditions using genomic-estimated breeding values(GEBVs).Also,the populations were simultaneously advanced using recurrent phenotypic selection(PS)by exposing them to managed drought and waterlogging and intermating tolerant plants from the two selection *** cycles per se(C1,C2,and C3)of the two populations developed using RCGS and PS approach and their test-cross progenies were evaluated separately in multilocation trials under managed drought,waterlogging,and optimal moisture *** genetic gains were observed with both GS and PS,except with PS in MYS-2 under drought and with GS in MYS-1 under *** genetic gains from GS were relatively higher under drought conditions(110 and 135 kg ha^(-1) year^(-1))compared to waterlogging(38 and 113 kg ha^(-1) year^(-1))in both MYS-1 and MYS-2,***,under waterlogging stress PS showed at par or better than GS as gain per year with PS was 80 and 90 kg ha^(-1),whereas with GS it was 90 and 43 kg ha^(-1) for MYS-1 and MYS-2,*** findings suggested that careful constitution of a multiparent population by involving trait donors for targeted stresses,along with elite highyielding parents from diverse genetic background,and its improvement using RCGS is an effe

关键词： Drought Genomic selection Maize Phenotypic selection Waterlogging

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