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Digital Text Document Watermarking Based Tampering Attack Detection via Internet

Computer Systems Science & Engineering 2024年第3期48卷 759-771页

作者： manal Abdullah Alohali Muna Elsadig Fahd N.Al-Wesabi Mesfer Al Duhayyim Anwer Mustafa Hilal Abdelwahed Motwakel Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Computer Science College of Science&Art at MahayilKing Khalid UniversityAbha62217Saudi Arabia Department of Computer Science College of Sciences and Humanities-AflajPrince Sattam bin Abdulaziz UniversityAl-Aflaj16733Saudi Arabia Department of Computer and Self Development Preparatory Year DeanshipPrince Sattam bin Abdulaziz UniversityAlKharjSaudi Arabia

Owing to the rapid increase in the interchange of text information through internet networks,the reliability and security of digital content are becoming a major research *** detection,Content authentication,and integrity verification of digital content interchanged through the Internet were utilized to solve a major concern in information and communication *** authors’difficulties were tampering detection,authentication,and integrity verification of the digital *** study develops an Automated Data Mining based Digital Text Document Watermarking for Tampering Attack Detection(ADMDTW-TAD)via the *** DM concept is exploited in the presented ADMDTW-TAD technique to identify the document’s appropriate characteristics to embed larger watermark *** presented secure watermarking scheme intends to transmit digital text documents over the Internet *** the watermark is embedded with no damage to the original document,it is then shared with the *** watermark extraction process is performed to get the original document *** experimental validation of the ADMDTW-TAD technique is carried out under varying levels of attack volumes,and the outcomes were inspected in terms of different *** simulation values indicated that the ADMDTW-TAD technique improved performance over other models.

关键词： Content authentication tampering attacks detection model security digital watermarking

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Rhabdomyosarcoma in Children: About 10 Cases

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Open Journal of Pediatrics 2024年第3期14卷 522-530页

作者： Ayad Ghanam manal Azizi Hind Zahiri Houssain Benhaddou Imane Kamaoui Amal Bennani Aziza El Ouali Abdeladim Babakhouya Maria Rkain Noufissa Benajiba Department of Pediatrics Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed First University Oujda Morocco Department of Pediatric Surgery Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed First University Oujda Morocco Department of Radiology Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed First University Oujda Morocco Department of Anatomopathology Mohammed VI University Hospital Faculty of Medicine and Pharmacy Mohammed First University Oujda Morocco

Introduction: Rhabdomyosarcoma (RMS) is a malignant soft-tissue tumor arising from striated muscle cells. It accounts for 60% - 70% of malignant mesenchymal tumors and 5% of pediatric cancers. Two-thirds of these cancers are diagnosed in children under 6 years of age, with a slight male predominance. Materials and Methods: This is a retrospective descriptive study of 10 cases of RMS collected in the pediatric hematology and oncology department of the Oujda university hospital, over a 5-year period, running from January 2018 to December 2022. Results: The median age at diagnosis was 3 years, with a sex ratio of 1. The mean time to diagnosis was 2 months. The most common site was the head and neck (50%), followed by the genitourinary tract (20%), the extremities (20%) and finally the abdomen (10%). The most frequent mode of discovery was a mass or swelling found in 90% of patients (all sites included), followed by exophthalmos in 30% of cases. At the diagnostic stage, CT scans were performed in 70% of cases and MRI in 5 patients (50%). Histological diagnosis was determined by immunohistochemical pathology in all our patients, with a predominance of embryonal (70%) versus alveolar (20%) and spindle cell types (10%). All patients underwent an extension workup, and a cervico-thoraco-abdominopelvic CT was performed in all patients (100%);MRI was performed in 2 patients (20%);lymph node involvement was present in 5 patients (50%). Metastases at the time of diagnosis were noted in only 1 patient (10%), who simultaneously presented with two metastatic sites;testicular and abdominal wall. Sixty percent of patients presented with advanced disease (high risk) and 40% with standard risk. Chemotherapy was used in all patients (100%), with upfront tumor resection performed in 40%. Fifty percent of patients received radiotherapy at a mean dose of 43 Gy, with the orbit the most frequently irradiated area (30%). All patients underwent CTscan and/or MRI and/or ultrasound surveillance.

关键词： Rhabdomyosarcoma Child Chemotherapy Surgery Radiotherapy

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Safety and effi cacy of hepatitis A vaccine in children with chronic liver diseas

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World Journal of Gastroenterology 2006年第45期12卷 7337-7340页

作者： Hanaa mostafa El-Karaksy manal Ismail El-Hawary Nehal Mohammad El-Koofy Rokaya El-Sayed Mona Al-Saeed El-Raziky Samah Asaad mansour Gamal Mohammad Taha Fatma El-Mougy Department of Pediatrics Cairo University Egypt Department of Pediatrics Fayoum University Egypt Department of Pediatrics Beni-Swaif University Egypt Department of Chemical Pathology Cairo University Egypt

AIM： To study the safety and efficacy of hepatitis A vaccine （HAV） in children with chronic liver disease of various etiologies. METHODS： Eleven children with chronic liver disease and thirteen age- and sex-matched controls negative for HAV antibodies were vaccinated against hepatitis A after they gave their informed consent. Children with uncontrolled coagulopathy or signs of hepatic decompensation were excluded. The vaccine （Havrix： 720 ELISA units in 0.5 mL, from GlaxoSmithKline Biologicals） was given intramuscularly in the deltoid in 2 doses 6 mo apart. Children were tested for HAV antibodies one and six months after the ist dose and one month after the 2^nd dose. Total serum bilirubin, alanine aminotransferase （ALT）, and aspartate aminotransferase （AST） were determined immediately before and after one month of the 1st dose of the vaccine. RESULTS： Only 7 out of the 11 patients were positive for HAV antibodies after the 1^st dose of the vaccine, as compared to 100% of the controls. One month after the 2nd dose, all patients tested were positive for HAV antibodies. No deterioration in liver functions of patients was noted after vaccination. No adverse events, immediate or late, were reported by the mothers after each dose of the vaccine. CONCLUSION： Hepatitis A vaccine is both safe and effective in this small studied group of children with chronic liver disease. Given the high seroconversion rate, post-vaccination testing for HAV antibodies is not needed.

关键词： Children Chronic liver disease Hepatitis A Hepatitis A vaccine

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Efficacy of extract from Ononis spinosa *** ethanol-induced gastric ulcer in rats

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Journal of Traditional Chinese Medicine 2021年第2期41卷 270-275页

作者： manal Ahmad Abbas Yasser Ibrahim Kandil manal Mohammad Abbas Faculty of Allied Medical Sciences Al-Ahliyya Amman UniversityAmman 19328Jordan Biochemistry Department Faculty of PharmacyAl-Azhar UniversityCairo 11884Egypt

OBJECTIVE:To investigate the efficacy of the extract from Ononis spinosa L.(***)on ethanol-induced gastric ulcer in ***:Phytochemical constituents of the extract from *** were analyzed using liquid chromatography-mass *** were classified into 4 equal groups;ulcer control received oral vehicle;positive control was administered with 40 mg/kg esomeprazole(standard drug)and 2 groups received 0.5 and 1 g/kg of *** extract,*** ulcer was induced by absolute ethanol(5 mL/kg)orally to all *** of ulcer index,cyclooxygenase-2(COX-2)expression and determination of total glutathione level in gastric mucosa were ***:Oral administration of the extract from *** at doses 0.5 and 1 g/kg lowered the ulcer indices by 80.39%and 98.71%,respectively,compared to 67.89%by esomeprazole(40 mg/kg).Histologically,treatment with the extract decreased necrosis and hemorrhage in mucosa and edema and infiltration by inflammatory cells in *** immunohistochemical technique,it was demonstrated that COX-2 expression increased in mucosa of animals treated with the extract as well as by *** and esomeprazole increased total glutathione level in the stomach compared to *** was the major compound of the extract followed by trifolirhizin,myricitrin,gentisic acid,cycloartenol and ***:The present study demonstrated that the extract from *** was able to protect gastric mucosa from ethanol injury by at least 2 mechanisms,namely the induction of COX-2 and decreasing oxidative stress in the stomach.

关键词： Ononis Stomach ulcer Cyclooxygenase 2 Ethanol Ulcer index

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Network Intrusion Detection Based on Feature Selection and Hybrid Metaheuristic Optimization

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Computers, Materials & Continua 2023年第2期74卷 2677-2693页

作者： Reem Alkanhel El-Sayed M.El-kenawy Abdelaziz A.Abdelhamid Abdelhameed Ibrahim manal Abdullah Alohali mostafa Abotaleb Doaa Sami Khafaga Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Communications and Electronics Delta Higher Institute of Engineering and TechnologyMansoura35111Egypt Department of Computer Science Faculty of Computer and Information SciencesAin Shams UniversityCairo11566Egypt Department of Computer Science College of Computing and Information TechnologyShaqra University11961Saudi Arabia Computer Engineering and Control Systems Department Faculty of EngineeringMansoura UniversityMansoura35516Egypt Information Systems Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of System Programming South Ural State UniversityChelyabinsk454080Russia Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia

Applications of internet-of-things(IoT)are increasingly being used in many facets of our daily life,which results in an enormous volume of *** computing and fog computing,two of the most common technologies used in IoT applications,have led to major security *** are on the rise as a result of the usage of these technologies since present security measures are *** artificial intelligence(AI)based security solutions,such as intrusion detection systems(IDS),have been proposed in recent *** technologies that require data preprocessing and machine learning algorithm-performance augmentation require the use of feature selection(FS)techniques to increase classification accuracy by minimizing the number of features *** the other hand,metaheuristic optimization algorithms have been widely used in feature selection in recent *** this paper,we proposed a hybrid optimization algorithm for feature selection in *** proposed algorithm is based on grey wolf(GW),and dipper throated optimization(DTO)algorithms and is referred to as *** proposed algorithm has a better balance between the exploration and exploitation steps of the optimization process and thus could achieve better *** the employed IoT-IDS dataset,the performance of the proposed GWDTO algorithm was assessed using a set of evaluation metrics and compared to other optimization approaches in 2678 CMC,2023,vol.74,no.2 the literature to validate its *** addition,a statistical analysis is performed to assess the stability and effectiveness of the proposed *** results confirmed the superiority of the proposed approach in boosting the classification accuracy of the intrusion in IoT-based networks.

关键词： Feature selection grey wolf optimization dipper throated optimization intrusion detection internet-of-things(IoT)

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Anomaly Detection for Internet of Things Cyberattacks

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Computers, Materials & Continua 2022年第7期72卷 261-279页

作者： manal Alanazi Ahamed Aljuhani College of Computing and Information Technology University of TabukTabuk71491Saudi Arabia

The Internet of Things(IoT)has been deployed in diverse critical sectors with the aim of improving quality of service and facilitating human *** IoT revolution has redefined digital services in different domains by improving efficiency,productivity,and *** service providers have adapted IoT systems or plan to integrate them as integral parts of their systems’operation;however,IoT security issues remain a significant *** minimize the risk of cyberattacks on IoT networks,anomaly detection based on machine learning can be an effective security solution to overcome a wide range of IoT *** various detection techniques have been proposed in the literature,existing detection methods address limited cyberattacks and utilize outdated datasets for *** this paper,we propose an intelligent,effective,and lightweight detection approach to detect several IoT *** proposed model includes a collaborative feature selection method that selects the best distinctive features and eliminates unnecessary features to build an effective and efficient detection *** the detection phase,we also proposed an ensemble of learning techniques to improve classification for predicting several different types of IoT *** experimental results show that our proposed method can effectively and efficiently predict several IoT attacks with a higher accuracy rate of 99.984%,a precision rate of 99.982%,a recall rate of 99.984%,and an F1-score of 99.983%.

关键词： Anomaly detection anomaly-based IDS cybersecurity feature selection Internet of Things(IoT) intrusion detection

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Association of E-cadherin (CDH1) gene polymorphisms and gastric cancer risk

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World Journal of Gastroenterology 2010年第27期16卷 34332-3436页

作者： mansour S Al-Moundhri manal Al-Khanbashi Mohammed Al-Kindi Maryam Al-Nabhani Ikram A Burney Abdulaziz Al-Farsi Bassim Al-Bahrani Medical Oncology Unit Department of MedicineCollege of Medicine and Health SciencesSultan Qaboos University Department of Clinical Genetics College of Medicine and Health SciencesSultan Qaboos University Department of Biochemistry College of Medicine and Health SciencesSultan Qaboos University National Oncology Center Royal Hospital

AIM:To investigate the associations between CDH1 gene polymorphisms and gastric cancer(GC) risk ***:We analyzed four CDH1 polymorphisms(+54 T>C,-160 C>A,-616 G>C,-3159 T>C) in an Omani population,by extraction of genomic DNA from the peripheral blood of 192 patients with GC and 170 control participants and performed CDH1 genotyping using DNA ***:CDH1-160-AA genotype was associated with an increased risk of GC(OR = 3.6,95% CI:1.1-11.8)(P = 0.03).There was no significant association between the other polymorphisms and GC *** haplotype analysis of +54 T>C,-160 C>A,-616 G>C,-3159 T>C genotypes revealed that the OR of CCGC and CAGC haplotypes was 1.5(95% CI:0.7-3.5) and 1.5(95% CI:0.2-3.0),but did not reach statistical ***:The current study suggests that the-160 AA genotype was associated with an increased risk of GC in Oman.

关键词： Gastric cancer Polymorphism CDH1

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Predictive control of a chaotic permanent magnet synchronous generator in a wind turbine system

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Chinese Physics B 2015年第1期24卷 177-183页

作者： manal Messadi Adel Mellit Karim Kemih Malek Ghanes LRE Laboratory Jijel University BP 98 ouled Aissa Jijel Algeria L2EI laboratory Jijel University BP 98 ouled Aissa Jijel Algeria ECS-ENSEA cergy-pontoise France 6 avenue du Ponceau 95014 Cergy-Pontoise Cedex

This paper investigates how to address the chaos problem in a permanent magnet synchronous generator（PMSG） in a wind turbine system. Predictive control approach is proposed to suppress chaotic behavior and make operating stable;the advantage of this method is that it can only be applied to one state of the wind turbine system. The use of the genetic algorithms to estimate the optimal parameter values of the wind turbine leads to maximization of the power ***, some simulation results are included to visualize the effectiveness and robustness of the proposed method.

关键词： permanent magnet synchronous generator chaotic system genetic algorithm predictive control

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Administration of tacrolimus in 50 liver transplantation patients

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Hepatobiliary & Pancreatic Diseases International 2002年第4期1卷 492-494页

作者： manal Abdel Ruzig the Institute of Organ Transplantation and Tongji

Objective: To present a good tacrolimus (FK506) administration protocol in liver transplantation. Methods: Fifty liver transplantation patients were classified into FK506 high-concentration (20 pa- tients), FK506 mid-concentration (20), CsA-FK506 (5) and FK506-CsA (5) groups. Clinical manifesta- tions, FK506 side-effects and pathological changes were observed. Results: The FK506 high-concentration group show- ed complications such as infection and liver function damage. The FK506 mid-concentration group show- ed excellent therapeutic results and some complica- tions easy to deal with. Conclusion: FK506 is a highly effective immunosup- pressive agent and the mid-concentration protocol is a better one.

关键词： tacrolimus liver transplantation

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Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach

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World Journal of Gastroenterology 2022年第2期28卷 242-262页

作者： Abeer Babiker Idris Alaa B Idris manal A Gumaa Mohammed Babiker Idris Amanda Elgoraish Mohamed mansour Dalia Allam Bashir MO Arbab Nazar Beirag El-Amin M Ibrahim Mohamed A Hassan Department of Agricultural Science and Technology Institute of Natural and Applied SciencesErciyes UniversityKayseri 38039Turkey Department of Medical Microbiology Faculty of Medical Laboratory SciencesUniversity of KhartoumKhartoum 11111Sudan Department of Neurosurgery Ribat University HospitalKhartoum 11111Sudan BioMérieux Clinical and Application Advisor Al-Jeel Medical Co.Riyadh 11422Saudi Arabia Department of Epidemiology Tropical Medicine Research InstituteKhartoum 11111Sudan Department of Gastroenterology Ibn Sina Specialized HospitalKhartoum 11111Sudan Department of Gastroenterology Modern Medical CentreKhartoum 11111Sudan Biosciences College of HealthMedicine and Life SciencesBrunel UniversityLondon UB83PHUxbridgeUnited Kingdom Department of Translation Bioinformatics Detavax BiotechKayseri 38350Turkey

BACKGROUND Helicobacter pylori(***)is a ubiquitous bacterium that affects nearly half of the world’s population with a high morbidity and mortality *** within the tumor necrosis factor-alpha(TNF-A)promoter region are considered a possible genetic basis for this *** To functionally characterize the genetic variations in the TNF-A 5’-region(-584 to+107)of Sudanese patients infected with *** using in silico *** An observational study was carried out in major public and private hospitals in Khartoum state.A total of 122 gastric biopsies were taken from patients who had been referred for *** DNA was *** of the TNF-A-1030 polymorphism was performed using PCR with confronting two-pair primer to investigate its association with the susceptibility to *** infection in the Sudanese ***,Sanger sequencing was applied to detect single nucleotide polymorphisms in the 5’-region(-584 to+107)of TNF-A in ***-infected *** analyses were used to predict whether these mutations would alter transcription factor binding sites or composite regulatory elements in this region.A comparative profiling analysis was conducted in 11 species using the ECR browser and multiple-sequence local alignment and visualization search engine to investigate the possible ***,a multivariate logistic regression model was constructed to estimate odds ratios and their 95%confidence intervals for the association between TNF-A-1030,sociodemographic characteristics and *** *** were statistically significant if PA,-76)was located at the in silico-predicted promoter region(-146 to+10),and it was predicted to alter transcription factor b

关键词： 5’-region Promoter TNF-A Helicobacter pylori In silico analysis Sudan

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