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Uranium measurements using laser-induced breakdown spectroscopy in lithium chloride-potassium chloride salt of pyroprocessing

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Plasma Science and Technology 2020年第7期22卷 110-115页

作者： Seul-ki HAN Se-Hwan PARK Seong-Kyu AHN Korea Atomic Energy Research Institute Yuseong-guDaejeon 34057Republic of Korea

In pyroprocessing,uranium(U) is recovered from molten LiCl-KCl salt,and,for safeguard purposes,it is important to analyze the U and Plutonium(Pu) concentrations in a timely *** the present work,salt samples containing U were *** laser used in the present work was an Nd:YAG laser with a wavelength of 532 nm,a laser energy on the sample of11.5 mJ,and a pulse repetition rate of 10 *** plasma emission light was measured with an Echelle spectrometer.A total of 100 points on the sample surface were measured as the laser incident position was *** U and potassium(K) peaks in the spectrum were *** and multivariate analyzes were conducted to determine the accuracy and limit of detection(LOD) of the laser-induced breakdown spectroscopy.

关键词： LIBS uranium(U) safeguards LOD

massive hemoptysis after a bronchoscopic biopsy in patients with endobronchial tuberculosis

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Chinese medical Journal 2014年第21期127卷 3837-3838页

作者： Eun Seok Kang Young Rak Choi ki man Lee Kang Hyeon Choe Jin Young An Department of Internal medicine College of Medicine Chungbuk National University Cheongju Korea

Endobronchial tuberculosis （EBTB） is an infectious disease occurring in the trachea or the bronchus with microbiological and histological evidences of tuberculosis. It is assumed a specific form or complication of t... 详细信息

关键词： endobronchial tuberculosis bronchoscopy massive hemoptysis

Ferroptosis inhibitors reduce celastrol toxicity and preserve its insulin sensitizing effects in insulin resistant HepG2 cells

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Journal of Integrative medicine 2024年第3期22卷 286-294页

作者： Jia-jia Liu Xue Zhang Bang-lan Cai man-man Qi Yong-bin Chi Bin Peng Deng-hai Zhang School of medicine Shanghai UniversityShanghai 200444China Shanghai Health Commission Key Lab of Artificial Intelligence-Based management of Inflammation and Chronic Diseases Shanghai Pudong Gongli HospitalSecondary Military Medical UniversityShanghai 200135China School of Basic medicine Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina

Objective:Research has shown that celastrol can effectively treat a variety of diseases,yet when passing a certain dosage threshold,celastrol becomes toxic,causing complications such as liver and kidney damage and erythrocytopenia,among *** this dichotomy in mind,it is extremely important to find ways to preserve celastrol’s efficacy while reducing or preventing its ***:In this study,insulin-resistant Hep G2(IR-Hep G2)cells were prepared using palmitic acid and used for in vitro ***-Hep G2 cells were treated with celastrol alone or in combination with Nacetylcysteine(NAC)or ferrostatin-1(Fer-1)for 12,24 or 48 h,at a range of *** counting kit-8assay,Western blotting,quantitative reverse transcription-polymerase chain reaction,glucose consumption assessment,and flow cytometry were performed to measure celastrol’s cytotoxicity and whether the cell death was linked to ***:Celastrol treatment increased lipid oxidation and decreased expression of anti-ferroptosis proteins in IR-Hep G2 *** downregulated glutathione peroxidase 4(GPX4)m *** docking models predicted that solute carrier family 7 member 11(SLC7A11)and GPX4 were covalently bound by ***,we found for the first time that the application of ferroptosis inhibitors(especially NAC)was able to reduce celastrol’s toxicity while preserving its ability to improve insulin sensitivity in IR-Hep G2 ***:One potential mechanism of celastrol’s cytotoxicity is the induction of ferroptosis,which can be alleviated by treatment with ferroptosis *** findings provide a new strategy to block celastrol’s toxicity while preserving its therapeutic effects.

关键词： Celastrol Insulin resistance Ferroptosis N-Acetylcysteine Palmitic acid molecular docking

Recent developments of emerging inorganic, metal and carbon- based nanomaterials for pressure sensors and their healthcare monitoring applications

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Nano Research 2021年第9期14卷 3096-3111页

作者： Kyowon Kang Jaejin Park kiho kim ki Jun Yu School of Electrical and Electronic Engineering YU-KIST InstituteYonsei UniversitySeoul 03722Republic of Korea

Recently,flexible pressure sensors have gained substantial research interest in bioelectronics because they can monitor the conditions of various organs,enable early diagnosis of diseases,and provide precise medical treatment by applying them to various parts of the *** particular,inorganic materials,metal and carbon-based materials are broadly used in novel structured pressure sensors from wearable devices to implantable *** the excellent electronic properties,distinctive morphologies,and remarkable mechanical and chemical stability of these materials,it is expected that these flexible pressure sensors can be the basis for new methods for human *** article covers an extensive review of the inorganic,metal and carbon-based flexible pressure sensor design strategies and sensing mechanisms studied in recent years for diverse applications such as tactile sensors,arterial pulse sensors,intracranial pressure sensors,intraocular pressure sensors,and bladder pressure *** section provides an overview by introducing the recent progress in flexible pressure sensors.

关键词： nanomaterial inorganic carbon pressure sensor wearable device implantable device

Giant magnetoimpedance effect in stress-joule-heated Co-based amorphous ribbons

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Science China(Physics,mechanics & Astronomy) 2012年第12期55卷 2372-2377页

作者： CHEN ShuangQin man QiKui DUN ChaoChao SHEN BaoLong Zhejiang Province Key Laboratory of magnetic materials and Application Technology Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology&EngineeringChinese Academy of SciencesNingbo 315201China Department of Physics Wake Forest UniversityWinston SalemNC 27109USA materials Science and Engineering Southeast UniversityNanjing 211189China

Co-based Co63Fe4B22.4Si5.6Nb5 amorphous ribbons with a width of 150 μm and a thickness of 50 μm were prepared by single-roller melt-spinning *** giant magneto-impedance(GmI) effect of the stress-joule-heated ribbons under applied tensile stress ranging from 37 to 148 mPa was *** results show that the spectra of GmI ratio *** direct current(dc) field(Hex) of the samples changes dramatically with annealing tension() and driving *** single-peak(SP) GmI curve with maximum GmI ratio of 260% and magnetic field sensitivity of 52%/Oe was obtained in the sample applied tensile stress of 74 mPa at frequency of 3.6 mHz.A three-peak behaviour appeared in the samples under σ of 111 and 148 *** uncommon three-peak behaviour was attributed to several factors,which effectively originated from the balance between domain-wall movement and magnetization rotation.

关键词： giant magnetoimpedance effect stress-joule-heated ribbon three-peak behaviour

Development of herbicide resistance genes and their application in rice

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The Crop Journal 2022年第1期10卷 26-35页

作者： man Jin Lei Chen Xing Wang Deng Xiaoyan Tang Shenzhen Institute of molecular Crop Design Shenzhen 518107GuangdongChina Guangdong Provincial Key Laboratory of Biotechnology for Plant Development School of Life SciencesSouth China Normal UniversityGuangzhou 510631GuangdongChina Institute of Plant and Food Sciences Department of BiologySouthern University of Science and TechnologyShenzhen 518055GuangdongChina Shenzhen Agricultural Technology Promotion Center Shenzhen 518055GuangdongChina

Rice is one of the most important food crops in the *** seriously affect the rice yield and grain *** recent years,there are tremendous progresses in the research and application of herbicideresistant genes in rice *** article reviews the working mechanisms of six herbicides(glyphosate,glufosinate,acetolactate synthase inhibitor herbicides,acetyl-Co A carboxylase inhibitor herbicides,hydroxyhenylpyruvate dioxygenase(HPPD)inhibitor herbicides and dinitroaniline herbicides),the resistance mutations of the corresponding herbicide-target genes,and the herbicide detoxification mechanisms by non-target *** are provided on herbicide-resistant rice materials obtained by transformation of exogenous resistance genes,by artificial mutagenesis and mutant screening,and by modifying the target genes through gene *** paper also introduces the current application of herbicide-resistant rice,points out problems that may be caused by utilization of herbicide resistant rice and solutions to the problems,and discusses the future prospects for the development of herbicideresistant rice.

关键词： Rice Herbicides Herbicide resistant genes Gene editing mutant

A tactile and airflow motion sensor based on flexible double-layer magnetic cilia

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microsystems & Nanoengineering 2023年第1期9卷 127-135页

作者： Jiandong man Junjie Zhang Guangyuan Chen Ning Xue Jiamin Chen State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of Sciences100190BeijingPeople’s Republic of China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of Sciences100049BeijingPeople’s Republic of China

Inspired by the concept of bionics,a tactile and airflow motion sensor based on flexible double-layer magnetic cilia is developed,showing extremely high sensitivity in both force and airflow *** upper layer of the magnetic cilia is a flexible material mixed with magnetic particles,while the lower layer is a pure flexible *** double-layer structure significantly improves magnetism while maintaining cilia *** addition,a metal tube pressing(mTP)method is proposed to overcome the difficulties in preparing large aspect ratio(over 30:1)cilia,offering simplicity and avoiding the use of large-scale mEmS *** developed sensor has a detection range between 0 and 60µN with a resolution of 2.1µN for micro *** also shows great detection ability for airflow velocity with a sensitivity of 1.43µT/(m/s).Experiments show that the sensor could be applied in surface roughness characterization and sleep apnea monitoring.

关键词： layer double motion

Integral stormwater management master plan and design in an ecological community

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Journal of Environmental Sciences 2014年第9期26卷 1818-1823页

作者： Wu Che Yang Zhao Zheng Yang Junqi Li man Shi Key Laboratory of Urban Stormwater System and Water Environment Beijing University of Civil Engineering and ArchitectureMinistry of Education Beijing Yuren Rainwater Eco-technology Co. Ltd. China Aviation Planning and Construction Development Co. Ltd.

Urban stormwater runoff nearly discharges directly into bodies of water through gray infrastructure in China, such as sewers, impermeable ditches, and pump stations. As urban flooding, water shortage, and other environment problems become serious, integrated water environment management is becoming increasingly complex and challenging. At more than 200 ha, the Oriental Sun City community is a large retirement community located in the eastern side of Beijing. During the beginning of its construction, the project faced a series of serious water environment crises such as eutrophication, flood risk, water shortage, and high maintenance costs. To address these issues, an integral storrnwater management master plan was developed based on the concept of low impact development （LID）. A large number of LID and green stormwater infrastructure （GSI） approaches were designed and applied in the community to replace traditional stormwater drainage systems completely. These approaches mainly included bioretention （which captured nearly 85th percentile volume of the annual runoff in the site, nearly 5.4 x 10^5 m3 annually）, swales （which functioned as a substitute for traditional stormwater pipes）, waterscapes, and stormwater wetlands. Finally, a stormwater system plan was proposed by integrating with the gray water system, landscape planning, an architectural master plan, and related consultations that supported the entire construction period. After more than 10 years of planning, designing, construction, and operation, Oriental Sun City has become one of the earliest modem large-scale LID communities in China. moreover, the project not only addressed the crisis efficiently and effectively, but also yielded economic and ecological benefits.

关键词： Ecological communityOriental Sun CityIntegral stormwater managementmaster planGreen stormwater infrastructureLow impact development

High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and machine Learning Approach

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Research 2023年第1期2022卷 153-167页

作者： Letao Yang Brian m.Conley Jinho Yoon Christopher Rathnam Thanapat Pongkulapa Brandon Conklin Yannan Hou ki-Bum Lee Department of Chemistry and Chemical Biology Rutgers UniversityThe State University of New JerseyPiscatawayNJ 08854USA

A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based ***,high-throughput investigation of the cell-type-specific biophysical cues associated with stem cell-derived neural interfaces continues to be a significant obstacle to *** this end,we developed a combinatorial nanoarray-based method for high-throughput investigation of neural interface micro-/nanostructures(physical cues comprising geometrical,topographical,and mechanical aspects)and the effects of these complex physical cues on stem cell fate ***,by applying a machine learning(mL)-based analytical approach to a large number of stem cell-derived neural interfaces,we comprehensively mapped stem cell adhesion,differentiation,and proliferation,which allowed for the cell-type-specific design of biomaterials for neural interfacing,including both adult and human-induced pluripotent stem cells(hiPSCs)with varying genetic *** short,we successfully demonstrated how an innovative combinatorial nanoarray and mL-based platform technology can aid with the rational design of stem cell-derived neural interfaces,potentially facilitating precision,and personalized tissue engineering applications.

关键词： overcome neural rational