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COVID-19 transmission and control in land public transport:A literature review

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Fundamental Research 2024年第3期4卷 417-429页

作者： Qiqi Luo Wenbing Liu Jiayuan Liao Zhongli Gu Xiaodan Fan Zhiwen Luo Xuelin Zhang Jian Hang Cuiyun ou School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong LaboratoryZhuhai 519082China Key Laboratory of Urban Meteorology China Meteorological AdministrationBeijing 100089China China Meteorological Administration Xiong'an Atmospheric Boundary Layer Key Laboratory Xiong'an 070001China Key Laboratory of Tropical Atmosphere-Ocean System(Sun Yat-sen University) Ministry of EducationZhuhai 519000China Guangdong Fans-tech Agro Co. LtdYunfu 527300China Welsh School of Architecture Cardiff UniversityCardiff CF103XQUnited Kingdom

Land public transport is an important link within and between cities,and how to control the transmission of COVID-19 in land public transport is a critical issue in our daily ***,there are still many inconsistent opinions and views about the spread of SARS-CoV-2 in land public transport,which limits our ability to implement effective *** purpose of this review is to overview the literature on transmission characteristics and routes of the epidemic in land public transport,as well as to investigate factors affecting its spread and provide feasible measures to mitigate the infection risk of *** obtained 898 papers by searching the Web of Science,Pubmed,and WHO global COVID database by keywords,and finally selected 45 papers that can address the purpose of this *** public transport is a high outbreak area for COVID-19 due to characteristics like crowding,inadequate ventilation,long exposure time,and environmental *** from surface touch transmission and drop spray transmission,aerosol inhalation transmission can occur not only in short distances but also in long *** ventilation is the most important factor influencing long-distance aerosol *** transmission factors(e.g.,interpersonal distance,relative orientation,and ambient conditions)should be noticed as well,which have been summarized in this *** address various influencing factors,it is essential to suggest practical and efficient preventive *** these,increased ventilation,particularly the fresh air(i.e.,natural ventilation),has proven to effectively reduce indoor infection *** preventive measures are also effective,such as enlarging social distance,avoiding face-to-face orientation,setting up physical partitions,disinfection,avoiding talking,and so *** research on the epidemic has intensified,people have broken down many perceived barriers,but more comprehensive studies on monitoring systems and preventi

关键词： Land transportation Infection risk Transmission route Mitigation measures COVID-19

Gut microbiota induced abnormal amino acids and their correlation with diabetic retinopathy

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 883-895页

作者： Sheng-Qun Jiang Su-Na Ye Yin-Hua Huang Yi-Wen ou Ke-Yang Chen Jian-Su Chen Shi-Bo Tang Aier Eye Hospital Jinan UniversityGuangzhou 510000Guangdong ProvinceChina Aier Eye Institute and Changsha Aier Hospital Changsha 410000Hunan ProvinceChina The First Affiliated Hospital of Bengbu Medical University Bengbu 233000Anhui ProvinceChina School of Public Health Anhui Medical UniversityHefei 230000Anhui ProvinceChina

AIM:To explore the correlation of gut microbiota and the metabolites with the progression of diabetic retinopathy(DR)and provide a novel strategy to elucidate the pathological mechanism of ***:The fecal samples from 32 type 2 diabetes patients with proliferative retinopathy(PDR),23 with nonproliferative retinopathy(NPDR),27 without retinopathy(DM),and 29 from the sex-,age-and BMI-matched healthy controls(29 HC)were analyzed by 16S rDNA gene *** fecal samples from PDR,DM,and HC groups were assayed by untargeted *** metabolites were measured using liquid chromatographymass spectrometry(LC-MS)*** between gut microbiota and fecal metabolites were ***:A cluster of 2 microbiome and 12 metabolites accompanied with the severity of DR,and the close correlation of the disease progression with PDR-related microbiome and metabolites were *** be specific,the structure of gut microbiota differed in four *** and richness of gut microbiota were significantly lower in PDR and NPDR groups,than those in DM and HC groups.A cluster of microbiome enriched in PDR group,including Pseudomonas,Ruminococcaceae-UCG-002,Ruminococcaceae-UCG-005,Christensenellaceae-R-7,was *** analysis showed that the glucose and nicotinate degradations were significantly higher in PDR group than those in HC ***,serine,ornithine,and arachidonic acid were significantly enriched in PDR group,while proline was enriched in HC *** analysis illustrated that arginine biosynthesis,lysine degradation,histidine catabolism,central carbon catabolism in cancer,D-arginine and D-ornithine catabolism were elevated in PDR *** analysis revealed that Ruminococcaceae-UCG-002 and Christensenellaceae-R-7 were positively associated with L-arginine,ornithine levels in fecal ***:This study elaborates the different microbiota structure in the gut from four *** relative abundance of

关键词： proliferative retinopathy gut microbiota Ruminococcaceae amino acid metabolism arginine

Programmable double-unlock nanocomplex self-supplies phenylalanine ammonia-lyase for precise phenylalanine deprivation of tumors

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Chinese Chemical Letters 2024年第8期35卷 455-459页

作者： Chunqing ou Meijia Xiao Xinyue Zheng Xianzhou Huang Suleixin Yang Yingying Leng Xiaowei Liu Xiuqi Liang Linjiang Song Yanjie You Shaohua Yao Changyang Gong Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu 610041China State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoAvenida da UniversidadeTaipaMacao 999087China School of Medical and Life Sciences Chengdu University of Traditional Chinese MedicineChengdu 611137China Department of Gastroenterology People’s Hospital of Ningxia Hui Autonomous RegionYinchuan 750002China

Essential amino acids(EAAs)deprivation is a potential antitumor approach because EAAs are critical for tumor *** efficiently inhibit tumor growth,continuous deprivation of EAAs is required,how-ever,continuous deprivation without precise control will introduce toxicity to normal ***,a programmable double-unlock nanocomplex(ROCK)was prepared,which could self-supply phenylalanine ammonia-lyase(PAL)to tumor cells for phenylalanine(Phe)*** was double-locked in physiological conditions when administered *** ROCK actively targeted to tumor cells by integrinαvβ3/5 and CD44,ROCK was firstly unlocked by cleavage of protease on tumor cell membrane,exposing CendR and R8 to enhance ***,hyaluronic acid was digested by hyaluronidase overexpressed in endo/lysosome of tumor cells,in which ROCK was secondly unlocked,resulting in pro-moting endo/lysosome escape and PAL plasmid(pPAL)*** pPAL could sustainably express PAL in host tumor cells until the self-supplied PAL precisely and successfully deprived Phe,thereby block-ing the protein synthesis and killing tumor cells ***,our precise Phe deprivation strategy effectively inhibited tumor growth with no observable toxicity to normal cells,providing new insights to efficiently remove intratumoral nutrition for cancer therapy.

关键词： Programmable double-unlock Essential amino acids deprivation Phenylalanine ammonia-lyase Self-supply Gene therapy

农业强国建设的历史逻辑、理论逻辑和实践逻辑

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经济纵横 2024年第9期 33-39页

作者：王欧农业农村部农村经济研究中心北京100810

农业强国是社会主义现代化强国的重要组成部分。我国自古以农立国,农业强国建设有着深厚的历史基础,重农兴农强农始终是国家治理的重要内容,也是历史演进的必然结果。在马克思主义唯物史观的指导下,农业强国建设注重发挥生产力在农业发... 详细信息

农业强国是社会主义现代化强国的重要组成部分。我国自古以农立国,农业强国建设有着深厚的历史基础,重农兴农强农始终是国家治理的重要内容,也是历史演进的必然结果。在马克思主义唯物史观的指导下,农业强国建设注重发挥生产力在农业发展中的核心作用,同时遵循生产关系适应生产力发展的客观规律,以实现农业现代化和农村经济的全面发展。在推进中国式现代化的进程中,中国共产党始终把农业作为国民经济的重要基础和支撑,围绕农业、农村、农民问题开展了一系列强国建设实践。脱贫攻坚取得全面胜利,乡村经济快速发展,乡村社会治理和生态文明建设不断进步,广大农民的综合素质日益提高,形成了以工补农、以城带乡、工农互促、城乡互补、协调发展、共同繁荣的新型工农城乡关系,为农业强国建设提供了坚实的实践基础。

关键词：农业强国历史逻辑理论逻辑实践逻辑

A novel small-animal locomotor activity recording device for biological clock research

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Animal Models and Experimental Medicine 2024年第1期7卷 71-76页

作者： Yi-Long Wu Ming Zhong Jun Yin Wei-Jie ou Yu-Bin Zhuang Nan-Wen Zhang Su Lin Yue-Yong Zhu Endoscopy Center The First Affiliated HospitalFujian Medical UniversityFuzhouChina Department of Endocrinology The First Affiliated HospitalFujian Medical UniversityFuzhouChina Chuangke Workshop Technology Co. LtdShenzhenChina Department of Digestive Nutrition Fujian Children's HospitalFuzhouChina Experimental Animal Center Fujian Medical UniversityFuzhouChina Department of Pharmacology Fujian Medical UniversityFuzhouChina Department of Hepatology Hepatology Research InstituteClinical Research Center for Liver and Intestinal Diseases of Fujian ProvinceThe First Affiliated HospitalFujian Medical UniversityFuzhouChina

The rodent running-wheel recording apparatus is a reliable approach for studying cir-cadian *** study demonstrated how to construct a simple and intelligent running-wheel recording *** running wheel was attached to the cage's base,whereas the Hall sensor was attached to the cage's ***,the RJ25 adaptor relayed the running signal to the main control ***,the main control board was connected to the USB port of the computer with the USB *** were collected using the online-accessible,self-created software *** Magturning,generated data were saved and exported in real ***,the device was validated by collecting data on the locomotor activities of mice under dif-ferent light *** conclusion,this new device can record circadian activity of *** device is appropriate for interdisciplinary investigations related to biological clock research.

关键词： biological clock circadian rhythm intelligent equipment locomotor activity running wheel

Tuning electronic properties of cobalt phthalocyanines for oxygen reduction and evolution reactions

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Science China Chemistry 2024年第1期67卷 398-407页

作者： Jianlin Jiang Zhen Liu Shuaijun Pan Xinnian Xia Bing Qin Yang Hu Xuxu Wang Jiamin Lan Yu Gu Encai ou Weijian Xu Joseph J.Richardson Rui Guo SINOPEC Research Institute of Petroleum Processing Co. Ltd.Beijing 100083China College of Chemistry and Chemical Engineering Hunan UniversityChangsha 410082China College of Chemistry and Materials Science Hunan Agricultural UniversityChangsha 410128China Department of Chemical Engineering The University of MelbourneParkville 3010Australia College of Environmental Science and Engineering Hunan UniversityChangsha 410082China School of Engineering RMIT UniversityMelbourneVictoria 3001Australia

Metal–phthalocyanines are a class of catalytically active materials promising in energy conversion and storage fields(e.g.,electrocatalysis).However,understanding and controlling the electrochemical properties in metal-phthalocyanine systems is ***,we elucidate the electrocatalytic origins of a series of cobalt-phthalocyanine molecular catalysts and finetune their electronic properties at the atomic level,both experimentally and *** interactions between the cobalt center and the local coordination environment are regulated by introducing either electron-donating or electron-withdrawing groups on the phthalocyanine ligand,and the spin-orbit splitting of cobalt is increased by~0.15 eV compared with the nonsubstituted ***,the aminated cobalt phthalocyanine-based electrocatalysts exhibit low free energies in the ratedetermining steps of the oxygen reduction(-1.68 eV)and oxygen evolution reactions(0.37 eV).This contributes to the high electrocatalytic activity(e.g.,a halfwave potential of 0.84 V and an overpotential of 0.30 V at 10 mAcm^(-2)),featuring a high selectivity of a four-electron pathway(i.e.,a negligible by-product of hydrogen peroxide).These catalysts also exhibit exceptional kinetic current density(Tafel slope of 100 mV dec^(-1))in oxygen reduction reactions,in addition to a superior power density(158 mWcm^(-2))and a high cycling stability(>1,300 cycles)in Zn-air batteries,outperforming the commercial Pt/C and/or RuO2counterparts.

关键词： interfacial wettability molecular catalysts carbon nanotubes density functional theory electrochemistry

Enhanced charge collection of AgNWs-based top electrode to realize high-performance,all-solution processed organic solar cells

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Science China Chemistry 2024年第10期67卷 3347-3356页

作者： Juanyong Wan Yang Chen Weijie Chen Jinfeng Xia Guang Zeng Jianlei Cao Chuang Jin Yunxiu Shen Xiaoxiao Wu Haiyang Chen Junyuan Ding Xue-mei ou Yaowen Li Yongfang Li Laboratory of Advanced Optoelectronic Materials Suzhou Key Laboratory of Novel Semiconductor-Optoelectronics Materials and DevicesCollege of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Soochow UniversitySuzhou 215123China State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials Jiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationCollege of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China Jiangsu Sidike New Materials Science and Technology Co. Ltd.Suqian 215400China

All-solution processed organic solar cells are the ultimate aim of printable photovoltaics,but their electrical losses arising from poor contact of top electrodes greatly limit efficiency *** solve the problem,a solution-processed hybrid top electrode was constructed using silver nanowires(AgNWs)as the skeleton and ZnO nanoparticles(ZnO-NPs)as the *** constructing the skeleton,a spin-rinsing treatment was first used to reduce the amount of the residual insulating polyvinylpyrrolidone wrapped around the AgNWs to promote intimate contact among the AgNWs in the ***,the ZnO-NPs matrix was deposited onto the AgNWs skeleton,bridging the AgNWs skeleton with the underlayer ZnO-NPs electron transporting layer(ETL).The underlayer ZnO-NPs ETL can also induce the growth of the ZnO-NPs matrix to minimize lattice mismatch,which creates additional transport channels from the ETL to the AgNWs skeleton for charge *** a result,the obtained electrode significantly enhances the electrical contact in the device,thus delivering record power conversion efficiencies of 16.04%and 14.54%for rigid and flexible all-solution processed OSCs,respectively.

关键词： solution-processed top electrode organic solar cells AgNWs electrical contact

参与式文化视角下图书馆阅读推广策略研究——基于小红书平台的调研

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图书馆学研究 2024年第6期 108-120页

作者：欧燕广西师范大学图书馆

以参与式文化视角研究图书馆阅读推广,有助于突破传统推广模式的限制,激发用户更积极地参与阅读推广过程。文章借助小红书平台调查图书馆阅读推广现状,分析“以馆找人”与“以人找馆”层面下图书馆阅读推广的基本情况,最后基于参与式生... 详细信息

以参与式文化视角研究图书馆阅读推广,有助于突破传统推广模式的限制,激发用户更积极地参与阅读推广过程。文章借助小红书平台调查图书馆阅读推广现状,分析“以馆找人”与“以人找馆”层面下图书馆阅读推广的基本情况,最后基于参与式生产、参与式互动、参与式营销3方面不足,提出以有意识的主动策略来提升参与式生产能力,从个体力量扩展至社群力量来增强参与式互动本领,拓展营销思维将受众转化为忠实用户等策略来推动图书馆阅读推广的进步与发展。

关键词：图书馆参与式文化阅读推广小红书

新生代农民工的家庭再生产与乡村发展——基于打工地和输出地的城乡多点研究

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中国农业大学学报（社会科学版） 2024年第1期41卷 151-171页

作者：王欧华中师范大学社会学院湖北省社会发展与社会政策研究中心

新生代农民工“离土出村”之后,其家庭再生产安排深刻影响乡村发展。基于打工地和输出地的城乡多点研究发现,由于打工城市的排斥,新生代农民工将家庭再生产嵌入乡村社会,形成代际联系紧密的直系留守家庭,通过拓展留守家庭经营、为下一... 详细信息

新生代农民工“离土出村”之后,其家庭再生产安排深刻影响乡村发展。基于打工地和输出地的城乡多点研究发现,由于打工城市的排斥,新生代农民工将家庭再生产嵌入乡村社会,形成代际联系紧密的直系留守家庭,通过拓展留守家庭经营、为下一代加盖房屋等促进了乡村发展。然而,近年来农民工输出地的县域城镇化提供了新的家庭再生产空间,很大一部分新生代农民工的家庭再生产发生上移,家庭劳动力和家庭经济资源从乡村抽离,造成留守家庭规模锐减、经营萎缩、盖房停滞等乡村空心化现象。与此同时,大量新生代大龄单身男工因难以实现家庭化而陷入家庭再生产残缺,与留守家庭的联系逐渐疏离,不愿参与留守家庭经营和房屋营建,导致农地抛荒、房屋破败、照护危机等乡村发展困境。本研究有助于修正新生代农民工“离土出村”造成乡村空心化的线性变革观点,突显家庭再生产分析对理解其与乡村发展的复杂关系的重要意义。

关键词：新生代农民工乡村发展家庭再生产县域城镇化