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Pyeloplasty According to Küss-Anderson-Hynes: Results and Complications at the Urology-Andrology Department of the Sino-Guinean Friendship Hospital

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Open Journal of Urology 2022年第9期12卷 471-477页

作者： Alimou Diallo Thierno Mamaou Oury Diallo Thierno Oumar Diallo Demba Cissé Sory Naby Camara Alpha Oumar Barry mamadou Barry Ibrahima bah Abdoulaye Bobo Diallo Oumar Raphiou bah Department of Urology Sino-Guinean Friendship Hospital Faculty of Health Sciences and Technologies Gamal Abdel Nasser University of Conakry Conakry Guinea National Ignace Deen Hospital Faculty of Health Sciences and Technologies Gamal Abdel Nasser University of Conakry Conakry Guinea National Ignace Deen Hospital Faculty of Health Sciences and Technologies Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Urology Kolda Regional Hospital Cheick Anta Diop University Dakar Senegal

Objective: Evaluate pyeloplasty according to Küss-Anderson-Hynes at the urology-andrology department of the Sino-Guinean Friendship Hospital. Patient and Method: This is a 3-year prospective descriptive study from January 1, 2018 to December 31, 2020. It focused on a sample of 21 patients, who had undergone pyeloplasty according to Küss-Anderson-Hynes. Results: The averages age of the patients was 24.24 years. Lumbar pain was the main reason for consultation in 71.43% of cases. pyeloplasty according to Küss-Anderson-Hynes alone was performed in 76.20% of cases. It was associated with lower pole vessel uncrossing in 14.29% of cases and in 9.52% of cases with pyelolithotomy. The main Postoperative complications consisted of surgical site infections (23.81%) and fistula of the pyelo-ureteral junction (9.52%). The result of the pyeloplasty evaluated after three years, was qualified as good in 13 patients (86.67%), conversely the result was declared bad in 2 patients or 13.33%. During the follow-up period, postoperatively, we had lost sight of 6 patients. Conclusion: Pyeloplasty according to Küss-Anderson-Hynes in addition to its excellent results reported by the literature was the only therapeutic alternative performed during this study. However, its indications are considerably reduced with the advancement of laparoscopy.

关键词： Pyeloplasty Küss-Anderson-Hynes Parietal Suppuration

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Deep Vein Thrombosis Revealing Prostate Cancer about a Case in the Cardiology Department of the Ignace Deen National Hospital in Conakry

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World Journal of Cardiovascular Diseases 2020年第8期10卷 608-613页

作者： Ibrahima Sory Barry Hadj Yaya El Balde Diarra Koivogui Abdoulaye Camara Aly Samoura mamadou Bassirou bah mamadou Aliou Balde Alpha Kone Ibrahima Sory Sylla Souleymane Diakite Moussa Kourouma Kokoulo Koivogui Mariam Beavogui mamadou Dadhi Balde Mamadi Conde Cardiology Service of Ignace Deen National Hospital Conakry Guinea Cardiology Department of DONKA National Hospital Conakry Guinea Military Health Service at the Battalion of the Headquarters Camp Almamy Samory TOURE Conakry Guinea

Introduction: Deep vein thrombosis is a frequent disease, its origin is most often multifactorial. Venous thromboembolic disease (MVTE) and cancer are two frequently entangled pathologies. Here we report the diagnosis of deep vein thrombosis that discovered prostate cancer in an 88-year-old Guinean man. On clinical examination, there was a painful and hot swelling of the right leg, an absence of sloshing of the calf, a positive sign of Homans. The digital rectal examination revealed an enlarged prostate with an irregular surface. Cardiopulmonary auscultation was normal. The electrocardiogram showed a regular sinus rhythm at 65 cycles/min, with no sign of enlarged cavities or conduction disturbance. Venous Doppler ultrasound of the lower limbs showed the presence of an extensive acute deep venous thrombosis of the right sural vein extended to the popliteal and to the homolateral deep femoral. The reino-vesico-prostatic ultrasound concluded in a heterogeneous prostatic hypertrophy with projection of a median lobe associated with a bladder of fight with an important post voiding residue evaluated at 170 ml;the rate of specific antigen of the prostate PSA was at 84.87 ng/ml. The pathology analysis made after a prostate biopsy puncture concluded with an adenocarcinoma with a Gleason score of 3. Conclusion: The association of venous thromboembolic disease (MVTE) and neoplasia is frequent. The existence of active cancer in a patient is a known risk factor for MVTE and, conversely, the discovery of a first episode of deep vein thrombosis (DVT) or pulmonary embolism (PE) may be the mode of revelation of cancer.

关键词： Deep Vein Thrombosis Prostate Cancer Elderly Conakry

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Cardiac Amyloidosis: A Case Report of Seven Patients

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World Journal of Cardiovascular Diseases 2022年第3期12卷 160-167页

作者： Ngardjibem Djita Ibrahima Sory2 Sylla Aissatou Barry Murielle Ahodakin Djibril Sylla Elhadj Yaya Balde mamadou Bachir bah Houzeiph Abdou Lassissi Alpha Kone Sana Soumra mamadou Aliou Balde Mariame Beavogui mamadou Dadhi Balde Noura Feniche Cardiology Department Alen&#231 on-Mamers Intercommunal Hospital Alen&#231 on France Gamal Abdel Nasser University of Conakry Conakry Republic of Guinea

Introduction: Cardiac amyloidosis is a rare and under-diagnosed disease. The objective of this study was to collect cases of cardiac amyloidosis in patients hospitalized in the cardiology department of the Centre Hospitalier Intercommunal Alençon-Mamers (CHICAM). Patients and Methods: This was a retrospective descriptive study of the records of patients diagnosed with cardiac amyloidosis. The study took place in the cardiology department of the CHICAM over 12 months (from January 1, 2020 to December 31, 2020). We included the files of patients in whom the diagnosis of cardiac amyloidosis was confirmed on the basis of clinical, echocardiographic, biological, scintigraphic and cardiac MRI evidence. Results: Seven patients were included. The mean age was 86.71 years. Six men for one woman. Most of the patients were in heart failure. There was one case of periorbital ecchymosis. Troponinemia was increased in three patients, NTproBNP was always high with a mean of 1000 ng/L. Cardiac echography showed a hyperbright septum in four cases, concentric hypertrophy of the left ventricle with a mean interventricular septum in diastole of 13.85 mm. Six cases were senile transthyretin amyloidosis (TTR), one case was mutated transthyretin amyloidosis (TTRm). Two cases of death were noted. Conclusion: Cardiac amyloidosis has a poor prognosis due to delayed diagnosis.

关键词： Cardiac Amyloidosis Echocardiography Heart Failure Myocardial Scintigraphy

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Thyroid Disease at the University Hospital of Conakry, Guinea

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Open Journal of Internal Medicine 2019年第4期9卷 105-111页

作者： Amadou Kaké mamadou Mansour Diallo Djibril Sylla Alpha mamadou Diallo Ibrahima Camara Abdoulaye Keita Thierno Amadou Wann Kadija Dieng mamadou Alpha Diallo Elhadj Zaï noul bah Mohamed Yakharé Camara Abdoulaye Bayo Naby Moussa Baldé Department of Endocrinology and Metabolic Diseases Donka University Hospital Conakry Guinea Department of Internal Medicine Donka University Hospital Conakry Guinea Department of ENT Donka University Hospital Conakry Guinea.

Objectives: To describe the epidemiological, clinical and therapeutic characteristics of thyroid disease at the University Hospital of Conakry, Guinea. Methods: This was a descriptive study with prospective data collection, carried out over the period of December 2016 to April 2019 at the endocrinology outpatient consultation at the University Hospital of Conakry. All the epidemiological, clinical and therapeutic data of the patients followed-up for thyroid disease were collected, analyzed and classified according to the epidemiological, clinical and therapeutic profile. The functional, morphological and autoimmune aspects of the thyroid gland were studied. Results: Out of a total of 3.517 endocrinology consultations during the study period, 204 patients were diagnosed with thyroid disease (180 women and 24 men, F/H ratio: 7.5). The average age was 47 ± 16 years. A total of 90 patients (44.33%) had hyperthyroidism, including 52 cases of Graves-Basedow disease (57.6%) and 24 cases of toxic multi-nodular goiter (32.6%). Hypothyroidism was confirmed in 25 patients (11%);about half (48%) of them had a complete thyroid surgery. The treatment of hyperthyroidism was exclusively done by synthetic antithyroid drugs, except 5 cases of Hashimoto disease with transient initial hyperthyroidism phase. Hypothyroidism was treated by hormone replacement therapy. Thyroidectomy, partial (n = 5) or total (n = 12), was performed for aesthetic discomfort (n = 6), cervical compression (n = 8) and suspicion of thyroid cancer (n = 3). Follow-up was considered regular in 40 cases (44%). Conclusion: Thyroid disease was frequent in this study conducted in Conakry and its clinical features were very diverse, dominated by hyperthyroidism mainly due to Grave disease. However, diagnostic and therapeutic strategies were hindered by the limitation in availability of biological and morphological explorations.

关键词： Goiter Hyperthyroidism Hypothyroidism Guinea

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Right Heart Failure Indicative of Ebstein’s Disease in Adulthood about a Case

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World Journal of Cardiovascular Diseases 2023年第9期13卷 613-618页

作者： Sana Samoura Alpha Koné Ibrahima Sory 2 Sylla mamadou Bachir bah Morlaye Soumaoro Aly Samoura Aboulaye Camara Ibrahima Sory Barry Elhadj Yaya Balde Mariama Beavogui mamadou Dadhi Balde Department of Cardiology Sino-Guinean Friendship Hospital Guinea Conakry Department of Cardiology CHU Ignace Deen National Hospital Guinea Conakry

Ebstein disease is a rare congenital malformation whose clinical presentation differs according to the anatomical form and age of the patient. In adults, it presents mainly in the form of right or global heart failure or rhythm disorders. Survival is exceptionally long in some forms. We report the case of a 70-year-old patient with Ebstein’s disease in right heart failure.

关键词： Ebstein’s Disease Right Heart Failure

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Family Dyslipidemia Revealed by a Cornean Bow in a Guinean

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World Journal of Cardiovascular Diseases 2020年第7期10卷 455-459页

作者： bah mamadou Bassirou Balde El Hadj Yaya Balde Alpha Ibrahima Beavogui Mariame Camara Abdoulaye Barry Ibrahima Sory Balde mamadou Aliou Sylla Ibrahima Sory Kone Alpha Ngaide Alhassane Aliou Mamy Adrien Balde mamadou Dadh Ignace Deen National Hospital Cardiology Department Conakry Republic of Guinea Department of Ophthalmology Department of the Armed Forces Conakry Republic of Guinea Cardiology Department of Donka National Hospital Conakry Republic of Guinea Department of Hospital Cardiology of Grand Yoff Dakar Senegal

Object: The aim of this study was to describe a familial dyslipidemia revealed by a corneal arch. Familial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form. He was a 43-year-old patient admitted with visual disturbance, xanthomatous papule and orange coloring at the level evolving for 5 years, no personal history of cardiovascular disease, having a family history of lipid disorders in siblings, as a cardiovascular risk factor: age over 50 and the male gender, normal cardio pulmonary examination, blood pressure at 120/80 mmhg, heart rate 78 bpm, in whom the ophthalmological examination shows a yellowish spot on the cornea (Figure 1). We report the case of familial dyslipidemia revealed by a corneal spot in Guinea.More recent studies increasingly suggest that it is much more widespread than previously thought: 1/200 to 1/400. Familial dyslipidemia is a rare and severe metabolic abnormality. It should be screened as early as possible like any other cardiovascular risk factor for atheroma to avoi

关键词： Corneal Arch Familial Dyslipidemia Guinea

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Clinical, Therapeutic and Evolutionary Profiles of Hypertensive Emergencies in the Cardiology Department of the Ignace Deen National Hospital (Conakry)

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World Journal of Cardiovascular Diseases 2023年第12期13卷 827-836页

作者： Balde Elhadj Yaya bah mamadou Bassirou Barry Ibrahima Sory Kone Alpha Keita Fatoumata Binta Soumaoro Morlaye Toure Aboubacar Doumbouya Amadou Dioulde Sylla Ibrahima Sory Diakite Souleymane Balde mamadou Dadhi Cardiology Department of the Ignace Deen Hospital Conakry Guinea

Introduction: Hypertensive emergencies are a reality in the cardiology department of the Ignace Deen National Hospital. The aim of this study was to determine the clinical, therapeutic and evolutionary profile of hypertensive emergencies in the cardiology department of the Ignace Deen National Hospital. Methods: This was a longitudinal descriptive study of patients admitted to the cardiology department of the Ignace Deen National Hospital for hypertensive emergencies, over a period of six (6) months from 1 October 2020 to 31 March 2021. Results: Among the 638 patients admitted to the cardiology department during the study period, 102 cases of hypertensive emergencies were identified, representing a frequency of 15.99%. The mean age of the patients was 56.65 ± 13.33 years, with extremes of 23 and 90 years, and the sex ratio was 1.91 in favour of men. The associated cardiovascular risk factors were: age (76.47%), smoking (41.18%), sedentary lifestyle (31.37%), obesity (16.67%), dyslipidaemia (12.75%), diabetes (11.76%) and excessive alcohol consumption (11.76%). The various clinical pictures found were: acute pulmonary oedema 39 cases (38.23%), acute coronary syndrome 31 cases (30.39%), stroke 17 cases (16.67%), hypertensive encephalopathy 11 cases (10.78%), acute renal failure 3 cases (2.94%) and aortic dissection 1 case (0.98%). The drugs used on admission were calcium antagonists (Nicardipine 10mg) in 58 cases (56.86%), diuretics (Furosemide 20mg) in 44 cases (43.13%), nitrates (Risordan 20mg) in 39 cases (38.23%) and beta-blockers in 31 cases (30.39%). In terms of outcome, 88 (86.27%) patients had improved. However, 12 (11.76%) deaths were recorded. Conclusion: Hypertensive emergencies are a worrying condition with a high prevalence in the cardiology department of the Ignace Deen National Hospital.

关键词： Emergency Hypertension Prevalence National Hospital Ignace Deen

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Comparative Study between Patients Treated with Conventional Radiotherapy and IMRT with Chemotherapy for Stage III - IVA Nasopharyngeal Carcinoma: A Single Institution Retrospective Report

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Journal of Cancer Therapy 2023年第12期14卷 451-464页

作者： Mamady Keita Juan Li Malick bah mamadou Aliou Diallo Alhassane Ismaël Touré Abou Camara Bangaly Traoré Abdoulaye Keita Wenbing Shen Department of Radiotherapy The Fourth Affiliated Hospital of Hebei Medical University Shijiazhuang China Cancer Department of Donka National Hospital Conakry Guinea Faculty of Health Sciences and Techniques of Gamal Abdel Nasser University of Conakry Conakry Guinea Department of ENT-CFS Donka National Hospital Conakry Guinea

Introduction: Nasopharyngeal carcinomas are the most radiation-sensitive tumours, and radiotherapy alone provides better local control. Objectives: To evaluate the clinical efficacy and acute and late toxicities of two different treatment regimens for locally advanced nasopharyngeal carcinoma. Methods: From 2014 to 2017, 150 cases of stage III and 68 cases of stage IVA nasopharyngeal carcinoma were treated. Of these, 137 received conventional radiotherapy plus chemotherapy, and 81 received intensity-modulated radiotherapy plus chemotherapy. Chemotherapy was given either as induction, concurrent or adjuvant therapy. Survival rates were calculated according to Kaplan Meier and compared with the Log-rank test. The RTOG or EORTC criteria were used to assess acute and late toxicities. Results: The median follow-up time was 21.5 months, and the 2-year locoregional relapse-free survival, distant metastases-free survival, and overall survival rates in the conventional radiotherapy plus chemotherapy group were 76%, 71% and 77%, respectively;in the intensity-modulated radiotherapy plus chemotherapy group, they were 97%, 84%, and 100%, respectively. The difference in survival between the two groups was significant (χ2 = 5.06, P = 0.028). The incidence of grade 2 and 3 xerostomia one year after radiotherapy was 45.1% and 30.9% versus 33.3% and 0%. Conclusion: Compared with conventional radiotherapy plus chemotherapy, intensity-modulated radiotherapy plus chemotherapy offers better locoregional relapse-free survival and overall survival in patients with stage III and IVA nasopharyngeal carcinoma, and may significantly reduce the occurrence of radiation-induced xerostomia.

关键词： Nasopharyngeal Carcinoma Conventional Radiotherapy Intensity Modulated Radiotherapy Chemotherapy Prognosis

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Pronostic Factors of Cerebral Toxoplasmosis in Department of Infectious and Tropical Diseases at Donka National Hospital

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Advances in Infectious Diseases 2019年第3期9卷 243-251页

作者： mamadou Saliou Sow Karamba Sylla Diao Cissé Fodé Abass Cissé Ibrahima bah Kadiatou Cissé Kadio Jean Jaques Olivier Kadio Department of Infectious and Tropical Diseases at Donka National Hospital Conakry Guinea Chair of Public Health Conakry Guinea Neurology Department of Ignace Deen National Hospital Conakry Guinea

Objectives: To identify predictive factors for poor prognosis during cerebral toxoplasmosis at Donka Hospital. Methods: It was a retrospective study of descriptive and analytic type lasting one year six months (18 months) from January 1st, 2016 to June 30th, 2017 which involved patients admitted and hospitalized for cerebral toxoplasmosis in HIV field. Data enter was performed by Epi data 3.1 software and SPSS 21 software for statistical analysis. The threshold of significance was p Results: We observed 87 cases of cerebral toxoplasmosis (CT). The mean age was 38.53 ± 12.16. The clinical signs were mainly infectious syndrome (100%), headache (69.0%), confusion (46.0%) and meningeal syndrome (41.4%). The lethality was 37.9%. Living with a partner (p = 0.007), CD4 at initiation of antiretroviral therapy 3 (p = 0.009), and coma (p = 0.02) were the factors associated with death. Conclusion: This study showed that cerebral toxoplasmosis is associated with very high morbidity and mortality in the Infectious Diseases Department of Donka National Hospital. Living in a relationship, CD4 counts at baseline 3 and coma were independently associated with death. Special attention to these factors associated with infectious resuscitation and primary prevention in patients with a CD4 T lymphocyte count below 200 cells/mm may improve the prognosis of this pathology.

关键词： Cerebral Toxoplasmosis HIV/AIDS Donka

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Prevalence of Metabolic Syndrome in the Medical-Surgical Emergency Department of the Donka National Hospital

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Open Journal of Internal Medicine 2023年第2期13卷 85-94页

作者： Djibril Sylla Amadou Kake Thierno Amadou Wann Mohamed Lamine Yaya bah Mhamed Ciré Keita Alhassane Barry mamadou Diakhaby Lansana Diaby Internal Medicine Department of the Donka National Hospital Conakry Guinea Medical and Surgical Emergency Department of the Donka National Hospital Conakry Guinea

Introduction: The metabolic syndrome (MS) corresponds to the coexistence of several metabolic disorders including three (3) factors out of five (5) in the same individual. These five (5) major criteria are central or abdominal obesity, hypertriglyceridemia, low High-Density Lipoprotein cholesterol (HDLc), hyperglycemia, and elevated blood pressure. It has been the subject of various definitions over the past 10 years. It is a clinical-biological entity recognized by the World Health Organization (WHO) in 1998, the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) in 2001, the International Diabetes Federation (IDF) in 2005, then the IDF Harmonization Consensus in 2009. The objective of this study was to determine the prevalence of metabolic syndrome in the medico-surgical emergency department of the Donka national hospital. Methods: This was a descriptive study, data collection took place from February 5 to July 5, 2022 and, covering all patients aged 16 and over, without distinction of sex, origin received in consultation in the medical unit in the emergency department of Donka and having agreed to participate in the study. Anthropometric, clinical and biological data were recorded. Results: We recruited 107 patients whose age ranged from 20 to 94 years with a mean age of 58.92 ± 13.78 years. The prevalence of metabolic syndrome in our study population was 6.30% with a female predominance of 73.83%. The most frequent components of the metabolic syndrome were abdominal obesity (100%) followed by hyperglycemia (85.98%) and hypertension (85.05%). Among the complications related to the metabolic syndrome, diabetes was found with (46.73%), hypertension (43.93%) and stroke (16.93%). Conclusion: Our results show a significant prevalence of the metabolic syndrome and its main complications, which were diabetes, hypertension and stroke. These data justify early detection and treatment strategies.

关键词： Prevalence Metabolic Syndrome Medicine Unit Donka National Hospital

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