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A Very Severe Obstructive Sleep Apnea Syndrome: In a Cause of Resistant Hypertension with One Sample Case

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World Journal of Cardiovascular Diseases 2021年第3期11卷 223-229页

作者： Baldé Elhadj Yaya Bah mamadou Bassirou Barry Ibrahima Sory Béavogui Mariama Sylla Ibrahima Sory Baldé mamadou aliou Koné Alpha Diallo mamadou Camara Abdoulaye Baldé Siradiou Baldé mamadou Dadhi Dièye Ousmane Condé Mamady Cardiology Department of the Ignace Deen Hospital Conakry Guinea Cardiology Department of Donka Hospital Conakry Guinea Sakina Clinic in Dakar Dakar Senegal

When blood pressure values remain above the target in a hypertensive patient treated concomitantly with three anti-hypertensive drugs including a diuretic, maximum well-tolerated doses, this is a resistant arterial hypertension. In this case, it is advisable to look for a secondary cause such as a drug intake that influencing the blood pressure or the presence of obstructive sleeping syndrome (OSAS). We report a clinical case of a patient with a high cardiovascular risk at the age of 50, hypertensive and diabetic, with dyslipidemia and obesity. He was on anti-hypertensive triple therapy at an optimal dose. Her diabetes was balanced with 6.4% glycated hemoglobin. Dyslipidemia has being treated. Despite healthy diet including a low sodium diet and weight loss, blood pres- sure target was not reached. With self-measurement, the mean arterial pressure was 180/110 mmHg and on ABPM it was 167/113 mmHg. The ventilatory polygraphy finds a severe OSA with an IAH = 56.6. Treatment with PCP (Con- tinuous positive pressure) allowed this patient to control blood pressure. The search for OSA should be systematic in face of resistant hypertension, in par- ticular in overweight or obese patients.

关键词： Obstructive Sleep Apnea Syndrome (OSAS) Resistant Hypertension Continuous Positive Airway Pressure (CPAP)

Frequency of Group A Beta-Hemolytic Streptococcal Angina in Children in the Department of Pediatrics of Donka National Hospital

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Open Journal of Pediatrics 2020年第4期10卷 610-616页

作者： mamadou Moustapha Diop Aissata Barry Emmanuel Camara Mohamed Lamine Diallo M’mah Aminata Bangoura Hasmiou Dia Saliou Bella Diallo mamadou aliou Doukouré Moustapha Kouyaté Narcisse Viani Gateu Tadjom mamadou Pathé Diallo Pediatrics Department Donka National Hospital Conakry Republic of Guinea Paediatric Medical Emergency Donka National Hospital Conakry Republic of Guinea Institute of Nutrition and Child Health Conakry Republic of Guinea Paediatrics Department Ignace Deen National Hospital Conakry Republic of Guinea Medical Centre and Health Counselling Conakry Guinea

Background: Angina is a common paediatric condition. It has certain peculiarities in children, particularly with regard to the frequency of bacterial germs and the use of diagnostic tests. The aim of this study was to determine the place of the rapid diagnostic test in the management of group A beta-hemolytic streptococcal angina in children in the paediatric ward at Donka National Hospital. Methods: This was a prospective descriptive study lasting 6 months from 1st February to 31st July 2019 concerning children aged between 3 and 15 years old who were diagnosed with angina. Epidemiological, clinical, para-clinical and therapeutic variables were studied. Results: Out of 1494 registered children, we collected 116 cases of angina (7.76%). Out of 52 patients who benefited from the rapid diagnostic test, we recorded 13 cases of angina due to group A beta-hemolytic strptococcus. The male sex was the most dominant with 31 cases (59.69%) and a G/F sex ratio of 1.47. The age group most affected was between 3 and 5 years old (50%). The average age of ou

关键词： Angina Frequency Clinic Treatment Pediatrics Donka

Ebstein Anomaly: A Clinical Case Series among Adolescents in Guinea

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World Journal of Cardiovascular Diseases 2023年第4期13卷 228-235页

作者： mamadou Bassirou Bah Elhadj Yaya Baldé mamadou aliou Baldé Thierno Siradjo Baldé Mariama Djalakhan Diallo Amadou Diouldé Doumbouya Ibrahima Sory Sylla Alpha Koné Ibrahima Sory Barry Souleymane Diakité Sana Samoura mamadou Diallo Abdoulaye Camara mamadou Dadhi Baldé Cardiology Department Ignace Deen Hospital Conakry Guinea Cardiology Department Donka Hospital Conakry Guinea

Ebstein’s anomaly is a rare congenital heart disease. We report a series of 4 cases of Ebstein’s anomaly discovered in adolescents. The mean age was 13.75 ± 0.96, with 3 boys and one girl. Three were in heart failure. The EKG showed atrial hypertrophy (1 case), right bundle branch block (1 case), Wolff-Parkinson-White (1 case), and atrial fibrillation (1 case). Cardiomegaly was present in all patients with a mean cardiothoracic index of 0.77 ± 0.03. On echocardiography, the mean apical displacement of the tricuspid septal leaflet was 22.5 ± 3.30 mm/m2, the Celermajer index was Grade 2 in 2 patients and Grade 4 in 2 patients. Depletive medical treatment was prescribed to 3 patients. Anticoagulant therapy was initiated in one patient. Two are awaiting surgery. One death was recorded, it was at Grade 4 of the Celermajer index.

关键词： Ebstein Anomaly Adolescent Congenital Heart Disease Guinea

Arterial and Venous Thrombosis following Vaccination against COVID-19 with Astra-Zeneca Vaccine Revealing Thrombophilia

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World Journal of Cardiovascular Diseases 2023年第4期13卷 198-204页

作者： Bah mamadou Bassirou Doumbouya Amadou Dioulde Balde mamadou aliou Balde Thierno Hamidou Sylla Ibrahima Sory Balde Elhadj Yaya Kone Alpha Barry Ibrahima Sory Samoura Sana Beavogui Mariam Diakité Souleymane Balde mamadou Dadhi Cardiology Department Ignace Deen Hospital Conakry Guinea Imaging Department Ignace Deen Hospital Conakry Guinea

Vaccination against COVID-19 is the most recognised means of containing the pandemic. Vaccines are not without side effects, particularly vascular thrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K, and the clinical evolution was favourable.

关键词： Thrombophilia Thrombosis Vaccine AstraZeneca

Dyspnea in a 26-Year-Old Woman with Fatal Left Atrial Myxoma

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World Journal of Cardiovascular Diseases 2023年第6期13卷 309-312页

作者： Ibrahima Sory Sylla mamadou aliou Baldé mamadou Bassirou Bah Sana Samoura Souleymane Diakité Alpha Koné Ibrahima Sory Barry Mariame Béavogui Djibril Sylla Elhadj Yaya Baldé Mamadi Condé mamadou Dadhi Baldé Department of Cardiology Ignace Deen National Hospital Conakry Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Cardiology Sino-Guinean Hospital Conakry Guinea Department of Internal Medicine CHU Conakry Guinea

Cardiac myxoma is one of the primary intracardiac tumours. We report the case of a left atrial myxoma in a 26-year-old female patient admitted for investigation of dyspnoea. Echocardiography led to the diagnosis of a giant hypermobile myxoma prolapsing into the left ventricle. The patient died before being evacuated for surgical treatment.

关键词： Myxoma Left Atrium Echocardiography

Myocardial Perfusion Abnormalities in Patients with Hereditary Hypertrophic Cardiomyopathy: A Study of Three Cases and Review of the Literature

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World Journal of Cardiovascular Diseases 2023年第6期13卷 289-296页

作者： Ngardjibem Djita Ibrahima Sory Sylla mamadou Bassirou Bah Felix Collard Sana Samoura mamadou aliou Baldé Souleymane Diakité Ibrahima Sory Barry Alpha Koné Elhadj Yaya Baldé Mariame Béavogui mamadou Dadhi Baldé Philippe Chevalier Department of Cardiology Alen&ccedilon Hospital Alen&ccedilon France Department of Cardiology CHU Ignace Deen Conakry Guinea Department of Cardiology Sino-Guinean Friendship Hospital Conakry Guinea Department of Cardiology CHU Lyon Lyon France

Introduction: Hypertrophic cardiomyopathy (HCM) belongs to the very heterogeneous group of cardiomyopathies. This study aimed to study myocardial perfusion abnormalities on scintigraphy and assess the risk of sudden death from ventricular arrhythmia in hereditary sarcomeric HCM. Patients and Methods: This is a retrospective and prospective descriptive study over 18 months (January 01, 2021, to July 31, 2022) on the records of patients over 18 with the diagnosis of hypertrophic sarcomeric cardiomyopathy with or without ventricular rhythm disorders and who have undergone myocardial scintigraphy. Results: Three patients were included. The average age of our patients was 66 years old. Dyspnea is the primary symptomatology found in our patients. One patient presented with syncope and unsustained ventricular tachycardia. His risk score for sudden death from ESC at five years is estimated at 6.45%, and the patient received an ICD in primary prevention. The average sudden death risk score of our patients was 3.78%. The mean LV wall thickness was 20 mm. The mean maximum left intraventricular gradient was 39 mmHg. Myocardial fibrosis was present in all our patients. Myocardial scintigraphy was normal in all cases. Conclusion: Hypertrophic cardiomyopathy is a very heterogeneous group of cardiomyopathies. The rhythmic risk is multifactorial and constitutes a significant prognostic factor.

关键词： Hypertrophic Cardiomyopathy Myocardial Scintigraphy Sudden Death Ven-tricular Arrhythmia

Ruptured Sub-Annular Mitral Aneurysm in the Pericardium: Report of a Case

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World Journal of Cardiovascular Diseases 2021年第9期11卷 458-463页

作者： Elhadj Yaya Baldé mamadou Bassirou Bah Amadou Djouldé Doumbouya Aissatou Tiguidanké Baldé mamadou Cellou Guissé Ibrahima Sory Barry Alpha Koné Mariam Béavogui Souleymane Diakité Ibrahima Sory 2 Sylla mamadou aliou Baldé Abdoulaye Camara mamadou Diallo Thierno Siradjo Baldé mamadou Dadhi Baldé Mamady Condé Cardiology Department of the Ignace Deen Hospital Conakry Guinea Cardiology Department of Donka Hospital Conakry Guinea

The sub-mitral annular aneurysm is a rare cardiac pathology. The etiologies are diverse, ranging from the congenital form to the idiopathic form, including the acquired form. The clinical case we report is that of a 27-year-old young man, with no particular history, admitted with a picture of global heart failure. A cardiac ultrasound diagnosed a ruptured mitral sub-annular aneurysm in the pericardium. The difficulty lies in the surgical management of this condition, due to the lack of an adequate cardiac surgery service in most of the countries in Africa south of the Sahara.

关键词： Sub-Annular Aneurysm Mitral Valve Intrapericardial Rupture

Otorhinolaryngology Diseases in HIV-Positive Patients: 208 Cases at the Donka National Hospital

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International Journal of Otolaryngology and Head & Neck Surgery 2023年第1期12卷 1-7页

作者： Abdoulaye Keita Ibrahima Diallo mamadou aliou Diallo mamadou Mouctar Ramata Diallo Sayon Kourouma Fofana Mamady Alpha Oumar Barry Mohamed Casimir Kaman Abdoulaye 1 Bayo Mohamed Karfalla Kaba Fodé Alpha Doumbouya mamadou Saliou Sow Department of ENT and HNS Donka University Hospital Conakry Guinea Department of ENT and HNS Mamou Regional Hospital Mamou Guinea Department of ENT and HNS Camp Samory Touré Conakry Guinea Department of ENT and HNS Kankan Regional Hospital Kankan Guinea Department of Infectious Diseases Donka University Hospital Conakry Guinea

Introduction: Otorhinolaryngology (ENT) diseases in patients living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/ AIDS) are relatively common and of concern to ENT specialists and other health professionals. Aim: It was to describe the epidemiological and diagnostic aspects of ENT and cervicofacial diseases in patients living with HIV/ AIDS. Material and Methods: This was a descriptive study with prospective data collection, conducted over a period of six months (September 16, 2019 to March 16, 2020), carried out at the ENT and Infectious Diseases Departments of the Donka National Hospital. Results: Of 522 HIV-positive patients, 208 (39.8%) presented with ENT diseases. Women represented 62.5% with a sex ratio of 0.6. The mean age was 42.21 years with extremes of 16 and 64 years. Housewives were the most represented (29.8%). Married people were the most affected (76.4%). Cervical involvement was present in 7.7% of patients. Otologic involvement accounted for 43.7%. Oral cavity and pharyngolaryngeal involvement accounted for 50.9%. Nasosinus involvement accounted for 55.7%. HIV type I was the most common (99.5%). Conclusion: Otorhinolaryngology diseases were frequent in HIV positive patients. They may constitute the first reason for consultation. However, these ENT diseases remain in appendix of the opportunistic diseases of HIV/AIDS taking the front stage.

关键词： Otorhinolaryngology Diseases Epidemiology HIV/AIDS Diagnosis Sub-Saharan Africa

Evaluation of the Knowledge, Attitudes and Practices of the Hospital Staff in the Management of High Blood Pressure in Conakry

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World Journal of Cardiovascular Diseases 2019年第5期9卷 354-359页

作者： Ibrahima Sory 2 Sylla Djibril Sylla Elhadj Yaya Baldé Aissatou Barry Mabintou Condé mamadou Bachir Bah mamadou aliou Baldé Sana Samoura Ibrahima Sory Barry Mariame Béaovogui mamadou Dadhi Baldé Mamadi Condé Cardiology Department Hospital Conakry Conakry Guinea Medico-Surgical Emergencies Department Hospital Donka Conakry Guinea

Introduction: High blood pressure is a real public health problem affecting more than one in three adults. The objective of this study was to evaluate the level of knowledge, attitudes and practices of health care personnel in the management of hypertension in Conakry. Methods: Descriptive transversal study of 6 months, from April 20, 2018 to September 20, 2018, which took place in the internal medicine departments of the two university hospital centers (CHU) of Conakry (Donka and Ignace Deen). The study population consisted of general practitioners and specialists, practicing in both departments for at least two years and who agreed to submit to our questionnaire. Results: At the end of the study, we included 140 doctors, 61% at Donka University Hospital and 39% at Ignace Deen University Hospital. The predominance was male with 113 men for 27 women with a sex ratio H/F = 4.18. General practitioners were the most represented with 95% against 5% specialists. Sixty-four percent of physicians gave an exact definition of hypertension, 56% of physicians confirmed the diagnosis of hypertension after 2 to 3 consultations. 19% offered monotherapy as first-line treatment, only 72% said that the duration of Antihypertensive treatment was for life. Conclusion: Theseresults demonstrate that it is essential to reflect on our daily practices for a good improvement in the quality of care for patients.

关键词： High Blood Pressure Knowledge Attitudes and Practices Conakry