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Food and Nutrition Sciences 2023年第7期14卷 638-656页

作者： Mariama Ciré Kourouma malick Mbengue Abdoulaye Thioye Coumba Touré Kane Laboratoire de Microbiologie Appliquée et de Génie Industriel (MAGI) Ecole Supérieure Polytechnique (ESP) Université Cheikh-Anta-Diop Dakar Senegal Department of Molecular Biology Institute for Health Research Epidemiological Surveillance and Training (IRESSEF) Dakar Senegal

This study aimed to investigate optimal fermentation conditions of biological acetic acid fermentation for vinegar production. Optimization was performed on 3 acetic acid bacteria strains namely VMA1, VMA7 and VMAO using Response Surface Methodology (RSM). A Box-Behnken-Design (BBD) was achieved with three different independent process parameters involving: fermentation temperature, original alcohol concentration and original acetic acid concentration and one dependent variable (acetic acid yield). The results showed that the mathematical models describe correctly the relationship between responses and factors (F values of the models (p R2 (coefficient of correlation) respectively 0.96, 0.94, 0.98, and adjusted R2 0.95, 0.92, 0.98). The maximum acidity was obtained respectively at fermentation temperatures, original alcohol concentrations and original acetic acid concentrations ranging from [37.5°C - 45°C], [16% - 20% (v/v)], [1.5% - 2% (w/v)] for VMA1, [40°C - 45°C], [14.5% - 20% (v/v)], [1.7% - 2% (w/v)] for VMA7 and [42°C - 45°C], [17% - 20% (v/v)], [1.5% - 2% (w/v)] for VMAO. The use of these acetic strains in the production of vinegar may seriously lead to a decrease or even an ablation of the costs related to the cooling of bioreactors especially in warm and hot countries, in the context of global warming.

关键词： Vinegar Response Surface Methodology Box-Behnken-Design Optimization

Linear and Nonlinear Stokes Waves Theory: Numerical Hydrodynamic and Energy Studies

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Open Journal of Fluid Dynamics 2023年第1期13卷 61-79页

作者： Alpha malick Ndiaye Fadel Diop Samba Dia Cheikh Mbow Laboratoire de Mécanique des Fluides et Transferts Département de Physique Faculté des Sciences et Techniques Université Cheikh Anta Diop (UCAD) Dakar Sénégal

The increase of wave energy in electricity production is an objective shared by many countries to meet growing demand and global warming. To analyze devices capable of converting the energy of sea waves into electrical energy, it is important to master the various theories of gravity waves and generation. We will in our work consider a numerical waves tank for an amplitude A=0.5, a wavelength λ=0.25 , an average height He=10 and a Froude number fixed at 1 × 105. Numerical wave channel analysis is used to reproduce the natural phenomenon of wave propagation in an experimental model. Wave makers are usually used to generate waves in the channel. In theory, the influence of an incident wave can be considered, as in the case of our study. In this study, the evolution of the hydrodynamic parameters and the energy transported in one wavelength can be determined by calculation. A change of variable will be done in this work to facilitate the writing of the boundary conditions at the free surface and at the bottom. The nonlinear Stokes theory will be studied in this case in order to provide hydrodynamic solutions through the Navier-Stokes equations to finally deduce the energetic results. To do this, the finite difference method will be used for the hydrodynamic results such as the velocity potential and the free surface elevation and the trapezium method of Newton for the energetic results. Thus, we will determine the energetic potential according to the decrease in the slope of the tank. To do this, we will take as values of beta representing the inverse of the slope of the tank, β=100, β=105, β=110 and β=105. .

关键词： Waves Tank Energy Waves Gravity Waves Navier-Stokes Numerical Nonlinear Stokes Theory

Rare Etiology of Reversible Hypokinetic Dilatated Heart Disease in Infants: Bland-White-Garland Syndrome (ALCAPA)

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World Journal of Cardiovascular Diseases 2023年第2期13卷 73-91页

作者： malick Bodian Pêngd-Wendé Habib Boussé Traore Mohamed Leye Joseph Salvador Mingou Woula Sanou diallo Fatou Aw Simon Antoine Sarr Khadimu Rassoul Diop Awa Ndiaye Ababacar Mbengue Mouhamadou Bamba Ndiaye Adama Kane Maboury Diao Cardiology Department Aristide Le Dantec Hospital Dakar Senegal Cardiology Service Grand Mbour Hospital Mbour Senegal Paediatric Service Principal Hospital of Dakar Dakar Senegal Radiology Service Principal Hospital of Dakar Dakar Senegal

Bland-White-Garland syndrome or ALCAPA is an abnormality of birth of the left coronary artery from the pulmonary artery. It is a diagnostic and therapeutic emergency because it is a curable cause of hypokinetic dilated heart disease in infants. We report through this clinical case, the fourth case of infantile ALCAPA diagnosed in Senegal in a 7-month-old infant. The symptomatology began around the age of 2 months, with a grumpy state associated with more marked crying and moaning during feedings and bowel movements. The mother reported hospitalization for a severe lung infection when she was 6 months old. The examination noted an infant in poor general condition, retarded growth and weight, and a 3/6th holosystolic murmur at the apex. Troponinemia was positive at 43.90 ng/L. The electrocardiogram showed Q waves on the lower side, a sub endocardial lesion on the upper side and a ST segment elevation in aVR. Doppler echocardiography showed dilated cardiomyopathy with a mean alteration of systolic function of the left ventricle at 37%, a mean mitral insufficiency and a strong suspicion of a birth anomaly of the left coronary artery. The CT scan confirmed the diagnosis of ALCAPA. Surgicalreimplantation of the left coronary artery at the aortic level was performed at 10 months of life with a favourable outcome at D50 postoperative.

关键词： ALCAPA Infant Adult Epidemiology Physiopathology Clinic Diagnosis Echocardiography Treatment Surgery Evolution Senegal

Contribution to the Petrographic and Geochemical Study of the Karthala Massif Lavas in the Bangaani Area, Grande Comore, Indian Ocean

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Open Journal of Geology 2023年第5期13卷 312-336页

作者： Samba Cissokho Adinane Ahamada Abdoulaye Ndiaye Diomaye Yatte Papa malick Ngom Department of Geology Faculty of Sciences and Technics Cheikh Anta Diop University of Dakar (UCAD) Dakar Senegal

The Bangaani area is located in the northwestern part of the Karthala Massif on the island of Grande Comore, about 10 km from the capital Moroni. It is essentially constituted of basalt plateaus outcropping in the form of pahoehoe and aa lava flows or in the form of massive vesicular or non vesicular basalt flows. Petrographic analysis of the massive basalts studied shows a porphyritic microlitic texture marked by the successive crystallization of olivines, opaque minerals, clinopyroxenes and plagioclases in a relatively abundant mesostasis. This crystallization sequence is typical of a high pressure environment corresponding to primary alkaline magmas. The geochemical study of major and trace elements shows that the basalts studied are under saturated in silica (47.24%) but rich in alkali (2.26%) and titanium (2.66%). They correspond to intraplate alkaline basalts of type oceanic island basalts (OIB) and present a primary character marked by relatively high contents of magnesium (6.69%), chromium (151.23 ppm), nickel (107.53 ppm) and scandium (27.15 ppm). The REE and multi-element diagrams confirm that the Karthala basalts are alkaline basalts of type OIB by their enrichment in LILE and their depleted character in HREE and HFSE. In terms of isotopic ratios, they are comparable to HIMU and EM I.

关键词： Bangaani Karthala Comore Alkaline Basalts OIB

Modified Atomic Orbital Theory of the O⁺ Ion Originating from 2D⁰ and 4S⁰ Metastable States

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Journal of Applied Mathematics and Physics 2022年第6期10卷 1873-1886页

作者： malick Sow Fatou Ndoye Babou Diop Alassane Traoré Abdou Diouf Boubacar Sow Department of Physics Atoms Lasers Laboratory Faculty of Sciences and Technologies University Cheikh Anta Diop Dakar Senegal

We report in this paper energy positions of the 2D0_2s22p2(1D)nd(2F);2D0_2s22p2(1D)nd(2D);2D0_2s22p2(1D)nd(2P);2D0_2s22p2(1D)ns(2D);2D0_2s22p3(3D)np(2P);2D0_2s22p3(3D0)np(2F), and 4S0_2s22p3(5S0)np(4P) Rydberg series in the photoionization spectra originating from 2D0 and 4S0 metastable states of O+ ion. Calculations are performed up to n = 20 using the Modified Orbital Atomic Theory (MAOT) [1]. The present results are compared to the experimental data of Aguilar et al. [2] which are the only available values. The accurate data presented in this work may be a useful guideline for future experimental and other theoretical studies.

关键词： Semiempirical Calculations Modified Orbital Atomic Theory Electron Correlation Calculations Atoms and Ions Rydberg Series Quantum Defect

Vitreous haemorrhage as the first presentation of undiagnosed Waldenstrom macroglobulinemia

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International Journal of Ophthalmology(English edition) 2021年第10期14卷 1639-1641页

作者： Christina S Lim Huzaifa malick Somnath Banerjee Department of Ophthalmology University Hospitals of Leicester NHS TrustInfirmary SquareLeicester LE15WWUnited Kingdom

Dear Editor, Waldenstrom macroglobulinemia(WM) is a rare type of non-Hodgkin’s lymphoma, commonly associated with hyperviscosity syndrome. Unlike non-Hodgkin’s lymphoma, its ocular manifestations are less well described in the literature. Here we present the first case of undiagnosed WM presenting with dense vitreous haemorrhage. The study was conducted in accordance with the principles of the Declaration of Helsinki. The informed consent was obtained from the subject.

关键词： globulin lymphoma Waldenstr

Surgical Treatment of Hyperparathyroidism Secondary to Chronic Renal Failure: Our Experience with the 7/8 Subtotal Parathyroidectomy Technique

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第1期11卷 25-30页

作者： Ahmadou C. Sall Mame S. Diouf Houra Ahmed Ngor Ndour Ciré Ndiaye Abdou Sy Richard E. A. Deguenonvo Evelyne S. Diom malick Ndiaye Abdourahmane Tall Bay K. diallo Issa C. Ndiaye Raymond Diouf ENT Department Fann National University Hospital Dakar Senegal ENT and Cervico-Facial Surgery General Hospital Idrissa Pouye de Grand-Yoff Dakar S&#233 né gal ENT Department Diamniadio Children Hospital Dakar Senegal ENT Department Peace Hospital of Ziguinchor Ziguinchor Senegal ENT Department Albert Royer Children Hospital Dakar Senegal

Introduction: Surgical management takes place, after a certain period of evolution, on particularly severe forms of secondary hyperparathyroidism, resistant to medical treatment. Subtotal parathyroidectomy is an effective technique in the treatment of these disorders. Method: Our study is retrospective of 33 cases of hyperparathyroidism secondary to chronic renal failure in dialysis patients operated by the 7/8 technique. Identified over a period of 10 years (January 2010 to December 2019), in the ENT department of the Fann University Hospital. Results: Out of 33 cases of secondary hyperparathyroidism, the average age of our patients was 51.24 years with a sex ratio of 0.43. Causal nephropathy was dominated by nephro-angiosclerosis, which was found in 27.27% of cases. Bone pain found in 23 patients or 69.69% was the predominant clinical sign. The average calcemia was 92.7 mg/l. Parathormone was dosed in all our patients and the average was 1611.05 ng/l. The consequences were clinically marked by recurrent paresis in one patient. No case of hematoma or postoperative infection was found. On the biological level 10 patients or 30.30% had a transient hypocalcaemia. The results were marked by a drop in PTH in 23 patients or 78.78% of cases. Conclusion: Subtotal parathyroidectomy remains an effective and beneficial therapeutic method for kidney failure patients with secondary hyperparathyroidism.

关键词： Secondary Hyperparathyroidism 7/8 Parathyroidectomy Transient Hypocalcemia Persistent Hyperparathyroidism

Photoionization Study of Cl II, Ar II and Kr II Ions Using the Modified Atomic Orbital Theory

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Journal of Modern Physics 2018年第14期9卷 2594-2622页

作者： Abdourahmane diallo Mamadou Diouldé Ba Jean Kouhissoré Badiane Momar Talla Gning malick Sow Ibrahima Sakho Department of Physics UFR Sciences and Technologies University Assane Seck of Ziguinchor Ziguinchor Senegal Department of Physics Faculty of Sciences and Techniques University Cheikh Anta Diop of Dakar Dakar Senegal

Resonance energies of the Cl II-[3s23p3(2D5/2)]nd and [3s23p3(2P3/2)]nd, Ar II-3s23p4(1D2)ns, nd and of the Kr II [4s24p4(1D2)]ns, nd and 4s24p4(3P2,3P1)]ns, 4s24p4(3D2)]ns, nd and 4s24p4(3D2, 1S0)]ns, nd Rydberg series are reported. Natural widths of the Ar II-[3s23p4(1D2)]ns, nd series are also reported. Calculations are done in the framework of the Modified Atomic Orbital Theory (MAOT). Excellent agreements are obtained with available theoretical and experimental data. High lying accurate resonance energies up to n = 40 are tabulated. The possibility to use the MAOT formalism report rapidly with an excellent accuracy the position of the excitation resonances as well as their width within simple analytical formulae is demonstrated.

关键词： Resonance Energies Rydberg Series Natural Widths Modified Atomic Orbital Theory (MAOT)

Effect of glycyrrhizic acid and 18β-glycyrrhetinic acid on the differentiation of human umbilical cord-mesenchymal stem cells into hepatocytes

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World Journal of Stem Cells 2021年第10期13卷 1580-1594页

作者： Abiha Fatima Tuba Shakil malick Irfan Khan Aisha Ishaque Asmat Salim Stem Cell Laboratory Dr.Panjwani Center for Molecular Medicine and Drug ResearchICCBSUniversity of KarachiKarachi 75270SindhPakistan

BACKGROUND End-stage liver disease is a global health complication with high prevalence and limited treatment ***-based therapies using mesenchymal stem cells(MSCs)emerged as an alternative approach to support hepatic *** vitro preconditioning strategies have been employed to strengthen the regenerative and differentiation potential of MSCs towards hepatic *** compounds of the triterpene class;glycyrrhizic acid(GA)and 18β-glycyrrhetinic acid(GT)possess diverse therapeutic properties including hepatoprotection and anti-fibrosis *** are capable of modulating several signaling pathways that are crucial in hepatic *** with hepato-protective triterpenes may stimulate MSC fate transition towards *** To explore the effect of GA and GT on hepatic differentiation of human umbilical cord-MSCs(hUC-MSCs).METHODS hUC-MSCs were isolated and characterized phenotypically by flow cytometry and immunocytochemistry for the expression of MSC-associated surface *** cells were treated with GA,GT,and their combination for 24 h and then analyzed at three time points;day 7,14,and ***-PCR was performed for the expression of hepatic *** of hepatic proteins was analyzed by immunocytochemistry at day *** acid Schiff staining was performed to determine the functional ability of treated *** The fusiform-shaped morphology of MSCs in the treatment groups in comparison with the untreated control,eventually progressed towards the polygonal morphology of hepatocytes with the passage of *** temporal transcriptional profile of preconditioned MSCs displayed significant expression of hepatic genes with increasing time of *** cells showed positive expression of hepatocyte-specific *** results were further corroborated by positive periodic acid Schiff staining,indicating the presence of glycogen in their ***,bi-nuclea

关键词： Glycyrrhizic acid 18β-glycyrrhetinic acid Hepatocyte differentiation Human umbilical cord-MSCs Mesenchymal stem cells

Variational Calculations of Energies of the (2snl) 1,3Lπand (2pnl) 1,3 LπDoubly Excited States in Two-Electron Systems Applying the Screening Constant per Unit Nuclear Charge

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Journal of Modern Physics 2021年第3期12卷 328-352页

作者： Momar Talla Gning Ibrahima Sakho Maurice Faye malick Sow Babou Diop Jean Kouhissoré Badiane Diouldé Ba Abdourahmane diallo Department of Physics Chemistry UFR Sciences and Technologies University of Thies Thies Senegal Department of Physics Faculty of Sciences and Techniques University Cheikh Anta Diop of Dakar Dakar Senegal Department of Physics UFR Sciences and Technologies University Assane Seck of Ziguinchor Ziguinchor Senegal

In this paper, resonance energies and excitation energies of doubly 2sns 1,3Se, 2snp 1,3P0, 2pnp 1,3De, 2pnd 1,3F0 and 2pnf 1,3Ge excited states of the helium isoelectronic sequence with Z ≤ 10 are calculated. Calculations are carried out in the framework of the variational procedure of the formalism of the Screening Constant per Unit Nuclear Charge (SCUNC). New correlated wave function of Hylleraas type is used. Precise resonance and excitation energies are tabulated and good agreement is obtained when a comparison is made with available literature values.

关键词： Doubly Excited States Helium Isoelectronic Sequence Screening Constant per Unit Nuclear Charge (SCUNC) Correlated Wave Function Resonance Energy Excitation Energies