检索结果-南通市图书馆

血液透析患者营养状况的评估、监测与评价及营养状况与透析充分性关系的研究

在线全文

学校读者我要写书评

暂无评论

血液透析患者营养状况的评估、监测与评价及营养状况与透析充分性...

作者： Niroj mali 昆明医科大学

学位级别：硕士

第一部分应用人体测量学指标、生化参数和改良主观定量评估法（MQSGA）评估血液透析患者营养支持的效果目的营养不良在血液透析患者中普遍存在,并与较高的发病率和死亡率有关。本研究采用人体测量学指标、生化参数和改良主观定量评估法... 详细信息

第一部分应用人体测量学指标、生化参数和改良主观定量评估法（MQSGA）评估血液透析患者营养支持的效果目的营养不良在血液透析患者中普遍存在,并与较高的发病率和死亡率有关。本研究采用人体测量学指标、生化参数和改良主观定量评估法（MQSGA）对维持性血液透析患者的营养支持效果进行评估。方法这个前瞻性观察研究共纳入62例患者（男32例,女30例;平均年龄49.81±13.86岁）,随机分为完全营养支持组（第1组）和部分营养支持组（第2组）,观察时间为2021年1月至2021年12月。在血液透析的第1个月和第12个月测量患者的人体测量学指标、MQSGA评分和生化参数。在完全营养支持和部分营养支持下维持性血液透析1年后,比较MQSGA评分;人体测量学指标包括:体重指数（BMI）、三头肌皮褶厚度（TSFT）、上臂围（MAC）和握力（HGS）及上臂肌围（MAMC）;生化指标包括:血清白蛋白（ALB）、血钙、血磷、甲状旁腺激素（IPTH）、血红蛋白（HGB）、甘油三酯（TG）、血清铁（Fe）、低密度脂蛋白（LDL）。结果本研究共纳入患者62例,其中男32例,女30例,年龄23～78岁,平均（49.81±13.86）岁。所有患者都完成了这项研究。表1显示了参与研究的患者的人口统计学数据。随机将患者分为完全营养支持组（40例）和部分营养支持组（22例）。第1组的中位年龄为51岁,相对年龄更大（范围:27-78岁）。第2组的中位年龄为47岁（范围:23-71岁）。在性别上,第1组和第2组患者分别为35%和81.8%的男性。MQSGA评分与MIS评分呈正相关（r=0.618,p:0.001）,而白蛋白（r=-0.282,p:0.027）、握力（r=-0.376,p:0.003）、干体重（r=-0.275,p:0.030）均与MQSGA评分呈负相关。治疗1年后,第1组iPTH、BMI、MQSGA评分、MIS降低,握力、干体重、白蛋白、Kt/Vurea、MAMC、TC、Hb升高,差异有统计学意义（P＜0.05）。第2组,MAMC、MAC、Hb、握力均下降,TC 升高（P＜0.05）。结论提供全面的营养支持能明显改善血液透析患者的整体营养状况,减少营养不良。同时,血液透析患者的营养状况可以通过MQSGA评分和人体测量学指标来评估。第二部分是否合并糖尿病对血液透析患者营养状况与透析充分性关系的研究目的根据血液透析患者是否合并糖尿病,分析其与营养状况、透析充分性的关系。为提高糖尿病肾脏病维持性血液透析患者的存活率和生活质量,分析透析充分性指数（Kt/V）与营养参数的关系。方法选取2021年1月至2021年12月在昆明医科大学第一附属医院肾内科血液净化中心进行维持性血液透析的患者121例。采用改良主观定量评估法（MQSGA）对两组患者进行营养评估。收集血清白蛋白（ALB）、总胆固醇（TC）、血肌酐（Scr）、血尿素氮（BUN）等实验室指标。人体测量包括体重指数（BMI）、三头肌皮褶厚度（TSFT）、上臂围（MAC）和握力（HGS）,测量工具包括握力计、软尺和皮下脂肪计。计算KT/V和尿素还原率（URR）。结果本研究共纳入121例患者,其中糖尿病肾病（DKD）组29例（23.96%）,非糖尿病肾病（NDKD）组 92 例（76.04%）。男 63 例,女 58 例,平均年龄（53.76±14.35）岁,75 例（61.98%）有不同程度的营养不良,仅46例（38.02%）营养良好。DKD组营养不良率为68.96%,明显高于NDKD组（59.7%）。DKD组与NDKD组比较,性别、年龄差异有统计学意义（P＜0.05）。DKD组MQSGA营养不良评分和营养不良发生率均高于NDKD组。DKD 组握力、MAC、MAMC 低于 NDKD 组,P＜0.05,SCr、ALB、TC、BUN 低于 NDKD组,差异有统计学意义（P＜0.05）。营养相关指标比较显示,透析充分组的ALB、TC、BUN、MIS（营养不良炎症评分）均高于透析不充分组（P＜0.05）。透析充分组的握力、TSF、MAC、MAMC、BMI、干体重、中性粒细胞/淋巴细胞比值（NLR）、血小板/淋巴细胞比值（PLR）均低于透析不充分组。握力、MAC、MAMC、BMI、干体重、NLR均有显著性差异（P＜0.05）。经Pearson相关分析,Kt/V与白蛋白（r=0.181）、总胆固醇（r=0.229）呈低度正相关,与白蛋白、总胆固醇呈显著正相关（P＜0.05）。结论维持性血液透析患者营养不良发生率较高,约61.98%的患者存在不同程度的营养不良。相较于非糖尿病肾病,维持性血液透析的糖尿病肾病患者营养不良发生率更高,营养不良更为严重,且透析充分性相对较差。透析充分性与营养状况评估指标显著相关。根据这些结果,应对维持性血液

关键词：营养评估人体测量 MQSGA 营养不良血液透析糖尿病肾病血液透析患者营养状况透析充分性

Comparative Study of Solubility of Tranquilizers(Alternative Date Rape Drugs)in Stomach Acid

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Journal of Pharmacy and Pharmacology 2021年第8期9卷 278-286页

作者： Aditya More Smitesh Nalage Anita mali Department of Forensic Science Yashavantrao Chavan Institute of ScienceSataraMaharashtraIndia(Autonomous)

Date Rape Drugs are the members of tranquilizers and sedative class of *** are the substances that make it easier for someone to rape or assault *** person who is administrated by these drugs can cause sleepiness,slow breathing,slow heartbeat rate,trouble in muscle coordination,loss of ***(gamma-hydroxybutyric acid),Rohypnol(flunitrazepam),Ketamine are generally considered as date rape *** Food and Drug Administration Department of Central Government of India considered this issue and placed these drugs under the schedule of Narcotic Drugs and Psychotropic Substances *** it is nearly impossible to get these drugs *** criminals have been searched new way through *** tranquilizers and sedatives are also being used for committing such *** drugs are also scheduled,but one can get them with prescription from a registered medical *** we carried out a comparative study of 3 tranquilizers from the benzodiazepine class that are Diazepam,Alprazolam,and Librium to check their dissolving rate in stomach *** of action time of drug can help an investigator to identify the class of drug and time of drug injected(early phase).In our study,we found that the dissolving period of Diazepam and Alprazolam is more than conventional drugs.

关键词： GHB(gamma-hydroxybutyric acid) Rohypnol(Flunitrazepam) Ketamine Narcotic Drugs Psychotropic Substances Act.

Broadband terahertz wave generation from an epsilon-near-zero material

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2021年第1期10卷 115-122页

作者： Wenhe Jia Meng Liu Yongchang Lu Xi Feng Qingwei Wang Xueqian Zhang Yibo Ni Futai Hu mali.Gong Xinlong Xu Yuanyuan Huang Weili Zhang Yuanmu Yang Jiaguang Han State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China Center for THz Waves and College of Precision Instrument and Optoelectronics Engineering Tianjin UniversityTianjin 300072China Shaanxi Joint Lab of Graphene International Collaborative Center on Photoelectric Technology and Nano Functional MaterialsInstitute of Photonics and Photon-TechnologyNorthwest UniversityXi'an 710069China School of Electrical and Computer Engineering Oklahoma State UniversityStillwaterOklahoma 74078USA

Broadband light sources emitting in the terahertz spectral range are highly desired for applications such as noninvasive imaging and ***,THz pulses are generated by optical rectification in bulk nonlinear crystals with millimetre thickness,with the bandwidth limited by the phase-matching *** we demonstrate broadband THz emission via surface optical rectification from a simple,commercially available 19nmthick indium tin oxide(ITO)thin *** show an enhancement of the generated THz signal when the pump laser is tuned around the epsilon-near-zero(ENZ)region of ITO due to the pump laser field enhancement associated with the ENZ *** bandwidth of the THz signal generated from the ITO film can be over 3 THz,unrestricted by the phasematching *** work offers a new possibility for broadband THz generation in a subwavelength thin film made of an ENZ material,with emerging physics not found in existing nonlinear crystals.

关键词： pump film matching

Observation of spectral modulation coupled with broadband transverse-mode-locking in an Yb:CALGO frequency-degenerate cavity

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Optics Letters 2019年第3期17卷 60-65页

作者： Yijie Shen Zhensong Wan Xing Fu mali.Gong State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instrument Tsinghua University

A frequency-degenerate cavity(FDC) is the resonator that the ratio of transverse and longitudinal mode frequency spacings is a simple rational number. When an optical resonator is close to the FDC, transverse-mode-locking(TML) takes place with drastic changes of laser mode. We report for the first time, to the best of our knowledge,the multi-frequency emission and spectral modulation effects coupled with TML in FDC. The Yb:CaGdAlO_4(Yb:CALGO) crystal with large gain bandwidth was used as a gain medium in an off-axis-pumped hemispherical FDC for realizing broadband emission. Interestingly, the spectrum can transform from a single smooth packet shape to a multi-peak structure; meanwhile, the transverse pattern accordingly transforms into some exotic wave-packet profiles through controlling off-axis displacement in a special degenerate state.

关键词： Observation spectral modulation frequency-degenerate cavity

A New Cyrtodactylus Species(Reptila:Gekkonidae)from Nan Province,Northern Thailand

在线全文

学校读者我要写书评

暂无评论

Asian Herpetological Research 2022年第2期13卷 96-108页

作者： Siriwadee CHOMDEJ Waranee PRADIT Parinya PAWANGKHANANT Chakkrapong KUENSAEN Apichaya PHUPANBAI mali.NAIDUANGCHAN Promporn PIBOON Korakot NGANVONGPANIT Zhiyong YUAN Yinpeng ZHANG Jing CHE Phuping SUCHARITAKUL Chatmongkon SUWANNAPOOM Department of Biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Research Center in Bioresources for Agriculture Industry and MedicineDepartment of BiologyFaculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Division of Fishery School of Agriculture and Natural ResourcesUniversity of PhayaoPhayao 56000Thailand International College of Digital Innovation Chiang Mai UniversityChiang Mai 50200Thailand Rabbit in the Moon Foundation Ratchaburi 70180Thailand Animal Bone and Joint Research Laboratory Department of Veterinary Biosciences and Public HealthFaculty of Veterinary MedicineChiang Mai UniversityChiang Mai 50100Thailand Excellence Center in Veterinary Bioscience Chiang Mai 50100Thailand Key Laboratory of Freshwater Fish Reproduction and Development Ministry of EducationSouthwest UniversityChongqing 400715China State Key Laboratory of Genetic Resources and Evolution and Center for Excellence in Animal Evolution and GeneticsKunming Institute of ZoologyChinese Academy of SciencesKunming 650223YunnanChina School of Environment Tsinghua UniversityBeijing 100084China

Here,a new species of bent-toed gecko,Cyrtodactylus phukhaensis ***.,is described from Doi Phu Kha,Nan province,Thailand based on molecular and morphological evidence.A phylogeny based on NADH dehydrogenase subunit 2(ND2)and its flanking tRNAs places the new species in the chauquangensis group as a sister taxon to Cyrtodact ylus *** new species can be differentiated from other members of the chauquangensis group by having a unique combina tion of 7 or 8 suprala bials,23-28 longitudinal rows of dorsal tubercles,8-10 infrala bials,9 femoral pores,7 precloacal pores,40-47 ventral scales,and a lack of bands crossingthe temporal *** addition,results from a chromosome study of *** *** that the new species has a diploid chromosome number of 40 with a fundamental number of *** formula of the karyotype was as follows:2n(40)=2m+4sm+*** findings suggest that further studies of Cyrtodactylus biodiversity in northern Thailand are needed.

关键词： bent-toed gecko Cyrtodactylus wayakonei Cyrtodactylus chauquangensis karyotype phylogeny taxonomy

在线全文

学校读者我要写书评

暂无评论

粤港澳大湾区区域一体化及其互动关系

地理学报 2019年第12期74卷 2455-2466页

作者：刘毅王云杨宇马丽粤港澳大湾区战略研究院广州510070 中国科学院地理科学与资源研究所中国科学院区域可持续发展分析与模拟重点实验室北京100101 中国科学院大学资源与环境学院北京100049

粤港澳大湾区一体化过程中存在跨社会制度、跨法律体系、跨行政等级的复杂性,必然会遭遇一系列的摩擦。发掘粤港澳之间合作与冲突的焦点与关键时间节点,是对粤港澳大湾区一体化研究的重要补充。本文通过GDELT全球新闻事件数据库梳理了... 详细信息

粤港澳大湾区一体化过程中存在跨社会制度、跨法律体系、跨行政等级的复杂性,必然会遭遇一系列的摩擦。发掘粤港澳之间合作与冲突的焦点与关键时间节点,是对粤港澳大湾区一体化研究的重要补充。本文通过GDELT全球新闻事件数据库梳理了粤港澳大湾区一体化发展的历史和现状,对粤港澳三地互动关系进行研究。结果发现:(1)内地与香港关系呈现出"M"型波动,两者之间的冲突被新闻媒体有所强化。(2)内地与澳门之间的政策与民意表现为较高的一致性,两者之间的言语合作是互动关系的主导因素。(3)内地与港澳之间的互动关系总体上变得更加紧密,合作与冲突的频率都在上涨,内地-香港关系在粤港澳互动关系中的重要性不断被凸显。(4)粤港澳大湾区一体化建设的推进过程中,实际合作项目相对短缺,缺少多元化的抓手。粤港的经济和科技的竞合关系和香港局势的发展是粤港澳互动关系的主要影响因素。未来,粤港澳大湾区区域协调发展不仅要关注区域政策在空间上的投影,更要关注其在社会舆论与新闻媒体上的投影,促进一体化建设从实体空间建设向虚拟、话语空间的综合引导转变,强化"硬联通"与"软联通"的互动。

关键词：粤港澳大湾区区域协同一体化 GDELT 互动一国两制

Syntheses and characterization of anti-thrombotic and anti-oxidative Gastrodin-modified polyurethane for vascular tissue engineering

在线全文

学校读者我要写书评

暂无评论

Bioactive Materials 2021年第2期6卷 404-419页

作者： Meng Zheng Jiazhi Guo Qing Li Jian Yang Yi Han Hongcai Yang mali.Yu Lianmei Zhong Di Lu Limei Li Lin Sun Yunnan Key Laboratory of Stem Cell and Regenerative Medicine Science and Technology Achievement Incubation CenterKunming Medical UniversityKunming650500China Department of Biomedical Engineering Materials Research InstituteThe Huck Institutes of the Life SciencesThe Pennsylvania State UniversityUniversity ParkPA16802USA Department of Neurology The First Affiliated HospitalKunming Medical UniversityKunming650500China Department of Cardiology The Second Affiliated HospitalKunming Medical UniversityKunming650032China

Vascular grafts must avoid negative inflammatory responses and thrombogenesis to prohibit fibrotic deposition immediately upon implantation and promote the regeneration of small diameter blood vessels(<6 mm inner diameter).Here,polyurethane(PU)elastomers incorporating anti-coagulative and anti-inflammatory Gastrodin were *** films had inter-connected pores with porosities equal to or greater than 86%and pore sizes ranging from 250 to 400μ*** of Gastrodin into PU films resulted in desirable mechanical properties,hydrophilicity,swelling ratios and degradation rates without *** released Gastrodin maintained bioactivity over 21 days as assessed by its anti-oxidative *** Gastrodin/PU had better anti-coagulation response(less observable BSA,fibrinogen and platelet adhesion/activation and suppressed clotting in whole blood).Red blood cell compatibility,measured by hemolysis,was greatly improved with 2Gastrodin/PU compared to other Gastrodin/PU ***,Gastrodin/PU upregulated anti-oxidant factors Nrf2 and HO-1 expression in H2O2 treated HUVECs,correlated with decreasing pro-inflammatory cytokines TNF-αand IL-1β in RAW 264.7 *** implantation in a subcutaneous pocket,PU was encapsulated by an obvious fibrous capsule,concurrent with a large amount of inflammatory cell infiltration,while Gastrodin/PU induced a thinner fibrous capsule,especially 2Gastrodin/***,enhanced adhesion and proliferation of HUVECs seeded onto films in vitro demonstrated that 2Gastrodin/PU could help cell recruitment,as evidenced by rapid host cell infiltration and substantial blood vessel formation in *** results indicate that 2Gastrodin/PU has the potential to facilitate blood vessel regeneration,thus providing new insight into the development of clinically effective vascular grafts.

关键词： Gastrodin Polyurethane Anti-coagulation Anti-inflammation Angiogenesis

Conception Innovation Design System Based on PDM Framework

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Aided Drafting,Design and Manufacturing 2004年第2期14卷 8-16页

作者： TANWu-zheng mali.zhuang ZHAOMing-xi XIAOShuang-jiu DepartmentofComputerScienceandEngineering ShanghaiJiaotongUniversityShanghai200030China

The system is based on the globally shared product model conforming to VRML Standard, and uses SmarTeam (PDM) system to integrate and encapsulate CAD, CAE and other application software for product development. The system takes sugarcane harvester? mobile telephone design analysis and evaluation as an example, and utilizes fuzzy evaluation principle to evaluate the design and simulation analysis results for decisions making. The platform provides a collaborative intelligent environment for the design of products, aiming at integrating people, process and data in the virtual product development. The multi-layered system architecture provides capability for KBM and conception innovation design process with a single unified data and process model so as to achieve true process streamlining and data integrity throughout the entire product development lifecycle, and hence improves enterprises efficiency.

关键词： PDM conception innovation design fuzzy reasoning system model I-DEAS

Wavefront sensing based on phase contrast theory and coherent optical processing

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2016年第7期25卷 179-184页

作者：黄磊边琪周晨露李腾浩巩马理 Center for Photonics and Electronics Department of Precision Instruments Tsinghua University

A novel wavefront sensing method based on phase contrast theory and coherent optical processing is proposed. The wavefront gradient field in the object plane is modulated into intensity distribution in a gang of patterns, making highdensity detection available. By applying the method, we have also designed a wavefront sensor. It consists of a classical coherent optical processing system, a CCD detector array, two pieces of orthogonal composite sinusoidal gratings, and a mechanical structure that can perform real-time linear positioning. The simulation results prove and demonstrate the validity of the method and the sensor in high-precision measurement of the wavefront gradient field.

关键词： wavefront gradients composite sinusoidal gratings phase contrast