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Hydroxyethylstarch revisited for acute brain injury treatment

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Neural Regeneration Research 2021年第7期16卷 1372-1376页

作者： Martin A.Schick malgorzata burek Carola Y.Forster Michiaki Nagai Christian Wunder Winfried Neuhaus Department of Anesthesiology and Critical Care Medical Center-University of FreiburgFreiburgGermany Faculty of Medicine University of FreiburgFreiburgGermany Department of Anaesthesia and Critical Care University Hospital WürzburgWürzburgGermany Department of Internal Medicine General Medicine and CardiologyHiroshima City Asa HospitalHiroshimaJapan Robert-Bosch-Krankenhaus Department of Anesthesiology and Intensive Care MedicineStuttgartGermany Competence Unit Molecular Diagnostics Center Health and BioresourcesAustrian Institute of Technology GmbHViennaAustria

Infusion of the colloid hydroxyethylstarch has been used for volume substitution to maintain hemodynamics and microcirculation after e.g., severe blood *** the last decade it was revealed that hydroxyethylstarch can aggravate acute kidney injury, especially in septic *** of the serious risk for critically ill patients, the administration of hydroxyethylstarch was restricted for clinical *** studies and recently published in vitro experiments showed that hydroxyethylstarch might exert protective effects on the blood-brain *** the prevention of blood-brain barrier disruption was shown to go along with the reduction of brain damage after several kinds of insults, we revisit the topic hydroxyethylstarch and discuss a possible niche for the application of hydroxyethylstarch in acute brain injury treatment.

关键词： acute subarachnoid hemorrhage astrocyte chronic kidney disease delayed cerebral ischemia microglia neurovascular unit osmotic pressure pericyte stroke traumatic brain injury

Underwater explosion effects of 60 mm H.E. mortar bomb on a cylindrical concrete structure-PIT

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Defence Technology（防务技术） 2019年第1期15卷 65-71页

作者： Faruk Razic burek Miralem Defense Technologies Department University of Sarajevo Faculty of Mechanical Engineering University of Sarajevo Pretis d.d. Igmanska bb

PIT tests are usually performed when a mass distribution of High Explosive(H.E) projectile fragments is required. This paper shows the underwater detonation effects of 60 mm, M90 H.E. mortar bomb filled with Comp. B on cylindrical concrete structure(concrete pipe closed at one end-similar to a PIT test)which is 2 m high(inner height) with inner diameter of also 2 m. Thickness of both wall and bottom of a pipe is 0.35 m. Detailed characteristics of concrete which is used for manufacturing of a pipe are specified. Mortar bomb is submerged directly in to the water(no free airspace around the bomb) with the nose pointing to the bottom of a pipe. Number and mass of fragments after detonation are presented by table and photographs. Fragments of dummy fuze, through which blasting cap was protruded, are collected and reassembled to form a shape of a fuze after detonation where expanding of fuze material due to a detonation products is visualized. After underwater detonation, detonation of the same mortar bomb is performed in an empty pipe and the effects of this kind of detonation are observed. Distance at which fragments generated from submerged mortar bomb will not reach concrete pipes wall is also determined.

关键词： Underwater explosion Mortar bomb Blast Comp B Dummy fuze Fragments

Technologies to Support Community Flood Disaster Risk Reduction

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International Journal of Disaster Risk Science 2016年第2期7卷 198-204页

作者： Ian McCallum Wei Liu Linda See Reinhard Mechler Adriana Keating Stefan Hochrainer-Stigler Junko Mochizuki Steffen Fritz Sumit Dugar Miguel Arestegui Michael Szoenyi Juan-Carlos Laso Bayas Peter burek Adam French Inian Moorthy International Institute for Applied Systems Analysis (IIASA) Practical Action Consulting South Asia Practical Action Latin America Zurich Insurance Group

Floods affect more people globally than any other type of natural hazard. Great potential exists for new technologies to support flood disaster risk reduction. In addition to existing expert-based data collection and analysis, direct input from communities and citizens across the globe may also be used to monitor, validate, and reduce flood risk. New technologies have already been proven to effectively aid in humanitarian response and recovery. However, while ex-ante technologies are increasingly utilized to collect information on exposure, efforts directed towards assessing and monitoring hazards and vulnerability remain limited. Hazard model validation and social vulnerability assessment deserve particular attention. New technologies offer great potential for engaging people and facilitating the coproduction of knowledge.

关键词： Crowdsourcing Disaster risk reduction Flood resilience Social media Volunteered geographic information (VGI)

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某些非肿瘤性疾病

实验动物科学 1985年第4期 109-115+125页

作者： J.D.burek J.A.Molello S.D.Warner 范国雄

一、引言鼠是一种小动物,它给人以恐慌和杂乱的感觉。实际上,它对人类生存的每个时期都起到一定的影响。后来,由于重视用小鼠试验为人类造福从而使医学史更丰富了。近代,由于动物研究得到了广泛的宣传才获得成就。关于人和环境条件的关... 详细信息

一、引言鼠是一种小动物,它给人以恐慌和杂乱的感觉。实际上,它对人类生存的每个时期都起到一定的影响。后来,由于重视用小鼠试验为人类造福从而使医学史更丰富了。近代,由于动物研究得到了广泛的宣传才获得成就。关于人和环境条件的关系在动物研究资料中已被肯定。因此,如果实验资料很有意义,则必须全面了解实验动物和小鼠的现状。 Thelma Dunn和Margaret Deringer最早从事关于小鼠非肿瘤性病理学的讨

关键词：小鼠肺发生范围老龄小鼠病变老龄鼠肾上腺皮质