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International Relations and Diplomacy 2016年第10期4卷 641-649页

作者： malgorzata borkowska-nowak The John Paul II University of Lublin Lublin Poland

The title of this paper refers to Michael Oakeshott＇s distinction between the politics of faith and the politics of scepticism. The ＂faith＂ expresses a belief in the capacity of government to concentrate all the power and resources upon the project of human improvement and perfection, while the ＂scepticism＂ is the politics of the powerless in which government cannot produce perfection and enjoys only limited opportunity of directing the activities of its subjects. The aim of this article is to revise Oakeshott＇s distinction in order to apply it to the discussion on inequalities affecting Europe. This discussion held by Chantal Mouffe, Ulrich Beck and Anthony Giddens focused on issues such as： modern patterns of inequality, the coexistence of different ethnic, religious and political forms of life, ＂legitimization＂ of social inequalities, the institutionalization of norms of equality, the problem of recognition, the common identity and so on. The key question is： How the values of equality and justice are best realized in the structure of modern society？ To answer this question, it is necessary not only to assess critilically the authority of governments, but also to examine possible ways of development of the idea of liberal democracy and power relations in contemporary political socidtts. What is our perspective on the way to solve these problems--the reinvention of politics or democratizing democracy？ Even if this research will not help us to find the best political project, however we may be less often cheated in this discussion by irrelevant and ambiguous arguments.

关键词： human perfection human imperfection inequalities liberal democracy globalization

Health hazards related to conidia of Cladosporium—biological air pollutants in Poland, central Europe

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Journal of Environmental Sciences 2018年第3期30卷 271-281页

作者： Elzbieta Weryszko-Chmielewska Idalia Kasprzyk malgorzata nowak Aneta Sulborska Joanna Kaczmarek Agata Szymanska Weronika Haratym Miroslaw Gilski malgorzata Jedryczka Department of Botany Lublin University of Life Sciences Department of Environmental Biology University of Rzeszow Laboratory of Aeropalynology Faculty of Biology Adam Mickiewicz University Department and Clinic of Dermatology University of Medical Sciences Institute of Plant Genetics Polish Academy of Sciences Institute of Bioorganic Chemistry Polish Academy of Sciences Department of Crystallography Faculty of Chemistry Adam Mickiewicz University

The spores of Cladosporium Link. are often present in the air in high quantities and produce many allergenic proteins, which may lead to asthma. An aerobiological spore monitoring program can inform patients about the current spore concentration in air and help their physicians determine the spore dose that is harmful for a given individual. This makes it possible to develop optimized responses and propose personalized therapy for a particular sensitive patient. The aim of this study was to assess the extent of the human health hazard posed by the fungal genus Cladosporium. For the first time, we have determined the number of days on which air samples in Poland exceeded the concentrations linked to allergic responses of sensitive patients, according to thresholds established by three different groups（2800/3000/4000 spores per 1 m^3 of the air）. The survey was conducted over three consecutive growing seasons（April–September, 2010–2012） in three cities located in different climate zones of Poland（Poznan, Lublin and Rzeszow）. The average number of days exceeding 2800 spores per cubic meter（the lowest threshold） ranged from 61（2010） through 76（2011） to 93（2012）, though there was significant variation between cities. In each year the highest concentration of spores in the air was detected in either Poznan or Lublin, both located on large plains with intensive agriculture. We have proposed that an effective, science-based software platform to support policy-making on air quality should incorporate biological air pollutant data,such as allergenic fungal spores and pollen grains.

关键词： Environmental contaminant Biological air pollution Inhalant allergy AsthmaAllergen Conidium

ON A CURVATURE CHARACTERIZATION OF RICCI-PSEUDOSYMMETRIC HYPERSURFACES

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Acta Mathematica Scientia 2004年第3期24卷 361-375页

作者： malgorzata Glogowska Department of Mathematics Agricultural University of Wroclaw Grunwaldzka S3 50-357 Wroclaw POLANDhe author presents a curvature characterization of Ricci-pseudosymmetric hypersurfaces in semi-Riemannian space forms Nsn+1(c) n>4.

The author presents a curvature characterization of Ricci-pseudosymmetric hypersurfaces in semi-Riemannian space forms Nsn+1(c), n>4.

关键词： Ricci-pseudosymmetric manifold pseudosymmetric manifold hypersurface Cartan hypersurface Clifford torus

DISC1 genetics, biology and psychiatric illness

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Frontiers in Biology 2013年第1期8卷 1-31页

作者： Pippa A. THOMSON Elise L.V. MALAVASI Ellen GRüNEWALD Dinesh C. SOARES malgorzata borkowska J. Kirsty MILLA The Centre for Molecular Medicine at the Medical Research Council Institute of Genetics and Molecular Medicine The University of Edinburgh Western General Hospital Crewe Road Edinburgh EH4 2XU UK Division of Psychiatry The University of Edinburgh Royal Edinburgh Hospital Edinburgh EH10 5HF UK Centre for Integrative Physiology The University of Edinburgh Edinburgh EH8 9XD UK

Psychiatric disorders arc highly heritable, and in many individuals likely arise from the combined effects of genes and the environment. A substantial body of evidence points toward D1SCI being one of the genes that influence risk of schizophrenia, bipolar disorder and depression, and functional studies of DISC1 consequently have the potential to reveal much about the pathways that lead to major mental illness. Here, we review the evidence that DISC1 influences disease risk through effects upon multiple critical pathways in the developing and adult brain.

关键词： DISC1 schizophrenia depression genetics neural pathways

21世纪的中波关系——“一带一路”对两国关系的促进作用研究

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21世纪的中波关系——“一带一路”对两国关系的促进作用研究

作者： nowak malgorzata 北京外国语大学

学位级别：硕士

中波关系从一开始就复杂而含糊不清。到目前为止,只有少数研究者试图对两个国家间的相互关系与合作进行更深入地研究。在两国关系中从一开始就存在着一种障碍,像世界强国总是试图让其盟友间保持紧密关系,并且不让他们对世界强国的对手... 详细信息

中波关系从一开始就复杂而含糊不清。到目前为止,只有少数研究者试图对两个国家间的相互关系与合作进行更深入地研究。在两国关系中从一开始就存在着一种障碍,像世界强国总是试图让其盟友间保持紧密关系,并且不让他们对世界强国的对手奉行独立政策。在中国的全球倡议开始时——新丝绸之路——两国关系发生了巨大的变化。本论文《21世纪的中波关系——“一带一路”对两国关系的促进作用研究》的目的是描述中华人民共和国与波兰共和国互相关系发展过程、贸易交换并且分析“一带一路”倡议和《17+1合作》如何促进双方的合作。本文的主要假设是:“中国与波兰在“一带一路”合作下由于带来了波兰诸多盈利和提高它在国际舞台上的地位,因此会引起两个国家的关系将来很可能变得更密切”。为了寻找近年来中波关系快速发展的原因并且能够更好地理解这个话题本文在防御性现实主义理论的基础上采用文献研究法。然后为了更充分地研究这个假设,在这里两个问题被提出:一、波兰的地理位置如何影响它的外交政策?二、波兰在欧盟里提高自己的地位对中波的关系会带来什么影响?本文引用的参考文献基本上是波兰文和中文。在这两种语言中大多数文献的目的是从两个方面介绍相互关系,并将其融合到更全面的研究中。为了更深入地了解中波关系的各个方面以及西方国家对中波关系的分析,在这里几个英文文献也被提出。本文从一个全新的视角来分析中波关系及其未来,将对已有的研究做出重要贡献。同时,由于此话题的中文参考文献资源不足,所以本论文可以促进中国对整个中东欧地区和波兰的研究更加多元化。论文由导论、正文(分三个章节)、结论和参考文献组成。导论部分介绍本文的研究背景、研究内容和意义。第一章介绍波兰对西方和非西方国家奉行的外交政策,以及历史和地理位置是如何塑造它的外交政策的。第二章描述新丝绸之路和在此倡议下出现的区域合作。最后一章深入地研究了在新丝绸之路和区域合作下的双边关系以及这种的情况对两国经济和国际地位产生的影响。然后在结论里对最重要的问题给予了答案,并提供了证据表明随着新丝绸之路的发展和区域合作中波关系将在未来变得非常密切。

关键词：波兰双边关系新丝绸之路

The Impact of Bed Temperature on Heat Transfer Characteristic between Fluidized Bed and Vertical Rifled Tubes

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Journal of Thermal Science 2016年第5期25卷 476-483页

作者： Artur Blaszczuk Wojciech nowak Czestochowa University of Technology Institute of Advanced Energy Technologies Dabrowskiego 73 AGH University Science and Technology Faculty of Energy and Fuels Czarnowiejska 30

In the present work,the heat transfer study focuses on assessment of the impact of bed temperature on the local heat transfer characteristic between a fluidized bed and vertical rifled tubes(38mm-O.D.) in a commercial circulating fluidized bed(CFB) *** transfer behavior in a 1296t/h supercritical CFB furnace has been analyzed for Geldart B particle with Sauter mean diameter of 0.219 and 0.246 *** heat transfer experiments were conducted for the active heat transfer surface in the form of membrane tube with a longitudinal fin at the tube crest under the normal operating conditions of CFB boiler.A heat transfer analysis of CFB boiler with detailed consideration of the bed-to-wall heat transfer coefficient and the contribution of heat transfer mechanisms inside furnace chamber were investigated using mechanistic heat transfer model based on cluster renewal *** predicted values of heat transfer coefficient are compared with empirical correlation for CFB units in large-scale.

关键词： Cluster renewal approach heat transfer coefficient bed temperature suspension density circulating fluidized bed

Application of Nanocrystalline LaNi_5-type Hydrogen Absorbing Alloys in Ni-MH_x Batteries

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Journal of Rare Earths 2004年第5期22卷 596-599页

作者： Jurczyk M nowak M Institute of Materials Science and Engineering Poznan University of Technology 60-965 Poznan PolandInstitute of Materials Science and Engineering Poznan University of Technology 60-965 Poznan Poland

The structure and electrochemical properties of nanocrystalline LaNi_5-type alloys were studied. These materials were prepared by mechanical alloying (MA) followed by annealing. The properties of hydrogen host materials can be modified substantially by alloying to obtain the desired storage characteristics. It was found that the partial substitution of Ni by Al or Mn in LaNi_(5-x)M_x alloy leads to an increase in discharge capacity. The alloying elements such as Al, Mn and Co greatly improved the cycle life of LaNi_5 material. For example, in the nanocrystalline LaNi_(3.75)Mn_(0.75)Al_(0.25)Co_(0.25) powder, discharge capacity up to 258 mAh·g^(-1) was measured (at 40 mA·g^(-1) discharge current). Furthermore, the effect of the graphite coating on the structure of some nanocrystalline alloys and the electrodes characteristics were investigated. The mechanical coating with graphite effectively reduced the degradation rate of the studied electrode materials. The combination of a nanocrystalline LaNi_5-type hydride electrodes and a nickel positive electrode to form a Ni-MH battery, was successful.

关键词： hydrogen absorbing materials electrode materials nanocrystalline materials Ni-MH_x batteries rare earths

Hepatitis C virus infection in children in the era of directacting antiviral

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World Journal of Gastroenterology 2018年第24期24卷 2555-2566页

作者： malgorzata Pawlowska malgorzata Sobolewska-Pilarczyk Krzysztof Domagalski Department of Paediatric Infectious Diseases and Hepatology Faculty of MedicineCollegium MedicumNicolaus Copernicus University Centre For Modern Interdisciplinary Technologies Nicolaus Copernicus University

Hepatitis C virus(HCV) infection remains an important global health problem with chronic infection affecting approximately 11 million children worldwide. The emergence of direct-acting antiviral(DAA) therapies and the development of non-invasive methods for the determination of liver fibrosis will significantly improve the management of paediatric patients with chronic HCV infection in subsequent years. For paediatric patients, a new era of highly effective DAA agents is beginning, and the first results of available clinical trials are very promising. In this era, the identification and monitoring of patients continues to be an important issue. The availability of non-invasive serological and imaging methods to measure hepatic fibrosis enables the identification of patients with significant or advanced liver fibrosis stages. This article summarizes the current data on the epidemiology and progress of research aimed to evaluate the new therapies and non-invasive methods for liver injury in paediatric patients with chronic hepatitis C.

关键词： biomarkers of liver injury adolescents epidemiology direct-acting antiviral Hepatitis C virus non-invasive methods children

WNT/β-catenin signaling in hepatocellular carcinoma:The aberrant activation,pathogenic roles,and therapeutic opportunities

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Genes & Diseases 2024年第2期11卷 727-746页

作者： Anna Gajos-Michniewicz malgorzata Czyz Department of Molecular Biology of Cancer Medical University of LodzLodz 92-215Poland

Hepatocellular carcinoma(HCC)is a liver cancer,highly heterogeneous both at the histopathological and molecular *** arises from hepatocytes as the result of the accumulation of numerous genomic alterations in various signaling pathways,including canonical WNT/β-catenin,AKT/mTOR,MAPK pathways as well as signaling associated with telomere maintenance,p53/cell cycle regulation,epigenetic modifiers,and oxidative *** role of WNT/β-catenin signaling in liver homeostasis and regeneration is well established,whereas in development and progression of HCC is extensively ***,we review recent advances in our understanding of how WNT/β-catenin signaling facilitates the HCC development,acquisition of stemness features,metastasis,and resistance to *** outline genetic and epigenetic alterations that lead to activated WNT/β-catenin signaling in *** discuss the pivotal roles of CTNNB1 mutations,aberrantly expressed non-coding RNAs and complexity of crosstalk between WNT/β-catenin signaling and other signaling pathways as challenging or advantageous aspects of therapy development and molecular stratification of HCC patients for treatment.

关键词： Cancer stem cells CTNNB1 mutations Liver cancer Non-coding RNA Tumor heterogeneity

POTENTIAL OPERATORS AND LAPLACE TYPE MULTIPLIERS ASSOCIATED WITH THE TWISTED LAPLACIAN

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Acta Mathematica Scientia 2017年第1期37卷 280-292页

作者： Adam nowak Krzysztof STEMPAK Instytut Matematyczny Polska Akademia NaukSniadeckich 800-656 WarszawaPoland Wydziat Matematyki Politechnika WroctawskaWyb.Wyspianskiego 2750-370 WroclawPoland

We study potential operators and,more generally,Laplace-Stieltjes and Laplace type multipliers associated with the twisted *** characterize those 1 ≤ p,q ≤ ∞,for which the potential operators are Lp—Lq *** result is a sharp analogue of the classical Hardy-Littlewood-Sobolev fractional integration theorem in the context of special Hermite *** also investigate Lp mapping properties of the Laplace-Stieltjes and Laplace type multipliers.

关键词： twisted Laplacian special Hermite expansion negative power potential op-erator fractional integral potential kernel spectral multiplier singular oscil-latory integral